From this article you will learn: why can there be high upper blood pressure at the normal lower blood pressure. At what age does it often occur, how to establish the diagnosis, how dangerous such a pathology is, and how to treat it.
Contents of the article:
- Causes of pathology
- Classification of
- Characteristic symptoms of
- Diagnosis
- Treatment methods
- Forecast
Elevated only upper pressure is called isolated systolic hypertension( abbreviated ISAH).Isolation of such hypertension into a separate species is associated with the difference in the mechanism of its development( in comparison with the "classical" one), in the effect on the target organs( kidneys, heart, retina, brain) and in the prognosis.
The incidence of ISAH is 2.4-14%, the main contingent of cases is over 60 years old. The increase in the percentage of this form of hypertension directly depends on age, and by 70-80 years more than 80% of patients with hypertension are diagnosed.
The reason for increasing the upper( systolic) pressure, while maintaining a normal lower( diastolic) pressure is a decrease in the dilatability of the main arterial vessels, especially the aorta, as the main one. At the physiological norm, the central arteries, due to their elasticity, accept and suppress the force of the cardiac output, evenly passing the blood further along the body. If the aortic wall becomes rigid, a higher pressure is required to "push" blood from the heart, while the function of small vessels does not suffer and the level of diastolic tension remains the same.
Increased pressure in the central arteries leads to a number of pathological changes:
- The expansion of left ventricular muscle( hypertrophy) in the left ventricle with a gradual decrease in its function is a failure of the heart.
- Disturbance of "smoothness" and speed of blood circulation on large arteries( reduction of blood supply to organs).
- Traumatisation of the inner layer of blood vessels( endothelium) by high blood pressure current leads to replacement of the damaged area with a connective tissue, increasing vessel stiffness and aggravating the disease.
- Development of active enzymes( renin, angiotensin, nitric oxide, etc.).Their action on the vascular wall under conditions of the disease leads to an increase in pressure and forms a pathological circle.
Why is this dangerous? Increased blood pressure - cause of insufficient blood flow in target organs:
| Body | Pathology |
|---|---|
| Heart | Chronic failure does not fully cope with simple physical activity( climbing stairs, cleaning the house, etc.) Acute insufficiency( infarct) with extensivedefeat leads to rapid death, and treated to chronic heart muscle failure |
| Brain | Chronic failure is the cause of a gradual decline in mental abilities( intelligence,memory, etc.) Acute insufficiency( stroke) can lead to death or severe disability with loss of ability to care for themselves |
| Kidney | Chronic failure leads to proliferation of connective tissue with a gradual decrease in function of Acute form is erased, provided the functionality of both kidneys |
| Retina | The chronic form is characterized by a gradual decrease in visual acuity Acute form is the cause of complete blindness for a short period of time |
In hypertension, when the upper pressure is raised, and the lower normal pressure, the risk of severe or fatal complications is 2-5 times higher in comparison with the form where both indicators are increased. But any type of arterial hypertension without treatment in 83% of cases leads to acute damage to the heart and brain - the main causes of death of the adult population of the world.
Given the mechanism of development of ISAH, there is no complete cure for the disease, but with constant therapy, with good control of pressure, the risk of death from complications is reduced by 25%.
Therapists and cardiologists are engaged in the diagnosis, treatment and supervision of patients with arterial hypertension. The development of complications requires the intervention of neurologists, nephrologists and oculists.
Causes of pathology
Secondary form of ISAg
Secondary ISAH is a complication of a number of pathologies:
| Disease group | Specific diseases |
|---|---|
| Hereditary and congenital disorders | Aortic coarctation Open arterial duct Polycythemia( increased erythrocyte count) |
| Cardiac and vascular disorders | Completeatrioventricular block( violation of cardiac contraction) Aortic valve deficiency Arteriosclerosis atherosclerosis Aortoarteriitisvascular lining) |
| Other disorders | Anemia Fever Thyrotoxicosis( high level of thyroid activity) |
Primary form ISAg
Primary or essential ISAH develops when two or more risk factors interact( these risk factors are the same for any form of hypertension):
- genetic defect;
- age-related changes in the vascular wall( decreased elasticity) and metabolic disorders( increased activity of pressure-stimulating hormones);
- atherosclerosis;
- smoking;
- overweight with impaired fat metabolism;
- diabetes;
- female sex( the incidence is two times higher).
Classification
| Classification by change in diastolic pressure level | Classification by |
|---|---|
| 1 type( 60%) - no increase. type 2( 40%), or "burnt out hypertension" - a gradual transition of the form with increased numbers of upper and lower pressure in ISAH. | Stable - fluctuations in the upper pressure are insignificant, a cryogenic increase is extremely rare. Labile or crisis - marked fluctuations in systolic pressure with frequent hypertensive crises. |
Characteristic symptoms of
ISAG in 50% of cases is asymptomatic until signs of impaired blood flow in the heart and brain. Manifestations are the same for all forms of hypertension:
- headaches of different localization and intensity;
- discomfort, pain in the projection of the heart;
- nonspecific symptoms of chronic cerebral blood flow insufficiency: fatigue, mood changes, memory problems, etc.;
- decreased vision, "flies" and darkening in the eyes.
In case of a crisis course at the height of pressure, severe headache, changes in vision, nosebleeds, dizziness may occur. But more than half of the patients have no specific clinical manifestations. A high level of pressure is an accidental finding at a doctor or at home;often the general state of health does not suffer, allowing to carry out usual loadings.
Secondary changes in blood flow in the main organs gradually reduces the ability to perform routine tasks and leads to disability.
Diagnosis
Diagnosis ISAG can deliver if the top pressure is stable ≥ 140 mm.gt;and the lower ≤ 90 mm.gt;Art. For an accurate assessment, daily monitoring of pressure outside the medical facility is performed.
In addition to meeting the criteria for diagnosis( other forms of hypertension are diagnosed by the same method), the type and form of ISAH are established during daily monitoring.
Methods of treatment
In cases of secondary ISAH, the disease that causes the pressure increase is treated.
Primary form of therapy is carried out by a combination of drugs from several groups:
| Group preparations | Examples |
|---|---|
| Diuretics | Indapamide Hypothiazid |
| Beta-blockers | Atenolol bisoprolol |
| Antagonists Calcium | Amlodipine verapamil |
| Angiotensin converting enzyme | enalapril Lisinopril |
| Angiotensin receptor blockers | Losartan Valsartan |
In the case of primary forms - treatment prolonged(sometimes lifelong).
Prognosis
Arterial hypertension, when the upper pressure is high, and the lower normal in 68% is combined with diabetes, lipid metabolism and coronary artery disease, which significantly increases the risk of vascular and cardiac complications.
In 75% of people in the older age group, the pressure increase is diagnosed, of which 52-87% have been diagnosed with ISAH.84% of the population dies every year from vascular pathology against the background of a constant form of high blood pressure.
Treatment of hypertension reduces mortality by 17%, and the risk of fatal complications( sudden death, stroke, heart attack) - by 32%.
There is no complete cure for the disease - hypertension requires constant, lifelong therapy, but carrying it out is the key to prolonging the quality and life span.
