Tablets from pressure: a list of the best drugs, no side effects

Table of contents of the article:

• The most effective drugs for high blood pressure
• Tablets against pressure with a fast effect
• Tablets against prolonged action
• Rating of drugs( in tablets) with their description
• Combined drugs
• Combination of several drugs
• Summary

Increase in blood pressureA / D) affects almost everyone after 45-55 years. Unfortunately, hypertension can not be completely cured, so hypertensive patients need to constantly take tablets from pressure to prevent hypertensive crises( pressure-boosting episodes-or hypertension) that endure a lot of consequences: from severe headaches to heart attacks or strokes.

Monotherapy( taking one drug) gives a positive result only at the initial stage of the disease. A greater effect is achieved with a combined intake of two or three agents from different pharmacological groups that need to be taken regularly. It should be borne in mind that the body becomes accustomed to any antihypertensive tablets and their effect weakens. Therefore, for stable stabilization of the normal A / D level, periodic replacement is necessary, which is performed only by the doctor.

The hypertensive patient should be aware that medications that reduce blood pressure are rapid and prolonged( prolonged) action. Preparations from different pharmaceutical groups have different mechanisms of action, i.e. to achieve an antihypertensive effect affect different processes in the body. Therefore, for different patients with hypertension, the doctor can prescribe different means, for example, atenolol is better for one to normalize the pressure, and the other is undesirable because of the reduction in the heart rate together with the hypotensive effect. In addition to directly reducing the pressure( symptomatic), it is important to influence the cause of its increase: for example, to treat atherosclerosis( if there is such a disease), to prevent the secondary diseases - infarction, cerebral circulation disorders, etc.

The table shows the general list of drugs from differentPharmgroups assigned for hypertension:

Pharmacological group	Names of preparations
Angiotensin receptor blockers, or sartans	Losartan, Valsartan, Eprosartan, Candesartan, Cardosal
Selective and nonselective β-blockers	atenolol, metoprolol, practolol, propranolol, pindolol, Bisaprolol
Alpha-blockers	terazosin Artezin, Doxazosin, Proksodolol, Urorek
ACE( angiotensin converting enzyme)	enalapril, captopril, Kizinopril, Prestarium, Zokardis
Diuretics( diuretics)	Indapamide, Furosemide, Torasemide, hydrochlorothiazide, Triamterene, Veroshpiron.
Calcium antagonists	Verapamil, Amlodipine, Diltiazem

Drugs that are prescribed for hypertension

These drugs are indicated for the treatment of hypertension( persistent increase in pressure) of any degree. The stage of the disease, age, the presence of concomitant diseases, the individual characteristics of the organism are taken into account when choosing a remedy, selecting a dosage, the frequency of administration, and the combination of drugs.

Tablets from the Sartan group are today considered to be the most promising and effective in the treatment of hypertension. Their therapeutic effect is due to the blocking of receptors to angiotensin II - a potent vasoconstrictor that causes a steady and rapid increase in A / D in the body. Tablets with long-term admission give a good therapeutic effect without the development of any undesirable consequences and withdrawal syndrome.

Important: Only a cardiologist or a district therapist is required to prescribe drugs for hypertension, as well as to monitor the patient's condition during therapy. An independently taken decision to start taking a hypertensive drug that helps a friend, neighbor or relative, can lead to disastrous consequences.

Further in the article we will talk about what drugs are most often prescribed from high blood pressure, about their effectiveness, possible side effects, and also about the schemes of combined reception. You will get acquainted with the description of the most effective and popular drugs - Losartan, Lisinopril, Renipril GT, Captopril, Arifon-retard and Veroshpiron.

list of the most effective drugs for

pressurized Valium the international name	preparation Trade name different drugmakers
Losartan	Lozap, Lorista
Valsartan	Nortivan, Teveten, Nortivan
Indopamid	Arifon retard, Lorvas CP
Hydrochlorothiazide	Hypothiazid
enalapril	Enap, Berlipril
Captopril	Kapoten
Nifedipine	Cordaflex
Lisinopril	Diroton, Lysinoton
Verapamil	Finoptin, Isoting, Flamon
Amlodipine	Norvasc, Amlodak, Amlokor
Metoprolol	Metokard, Egilok
Diltiazem	cardio Diakordin

tablets for hypertension with rapid effect

List antihypertensives quick action:

Drugs for fast acting hypertension

At high pressure, it is enough to put half the tongue or a whole tablet of Captopril or Adelfan and dissolve. The pressure will drop in 10-30 minutes. But it is worthwhile to know that the effect of taking such funds is short-lived. For example, Captopril the patient is forced to take up to 3 times a day, which is not always convenient.

The action of Furosemide related to loop diuretics is the rapid occurrence of severe diuresis. Within an hour after taking 20-40 mg of the drug and in the next 3-6 hours you will often urinate. Arterial pressure will be reduced by removing excess fluid, relaxing the smooth muscles of blood vessels and reducing the volume of circulating blood.

Tablets against prolonged-on hypertension

List of antihypertensive drugs of prolonged action:

• Metoprolol,
• Diroton,
• Losartan,
• Cordaflex,
• Prestarium,
• Bisoprolol,
• Propranolol.

Long-acting hypertension drugs

They have an extended therapeutic effect, designed for the convenience of treatment. These medicines are enough to take only 1 or 2 times a day, which is very convenient, because hypertension maintenance therapy is shown constantly until the end of life.

These drugs are used for long-term combination therapy for hypertension of 2-3 degrees. Features of the reception are a long-term cumulative effect. To obtain a stable result, you need to take these drugs for 3 or more weeks, so do not stop taking the medication if the pressure does not decrease instantly.

Rating of tablets against hypertension with their description

The list of antihypertensive drugs is composed, starting from the most effective with a minimum of undesirable consequences to drugs with more frequent side effects. Although in this regard everything is individual, it is not in vain to carefully select and, if necessary, adjust antihypertensive therapy.

Losartan

A drug from the Sartan group. The mechanism of action is to prevent the potent vasoconstrictive action of angiotensin II on the body. This substance, which has a high activity, is obtained by transformations from renin, produced by the kidneys. The drug blocks the receptors of the AT1 subtype, thereby preventing vasoconstriction.

Systolic and diastolic A / D decreases after the first oral administration of Losartan, the largest after 6 hours. The effect persists for 24 hours, after which it is required to take the next dose. Stance of stabilization of pressure should be expected after 3-6 weeks from the beginning of admission. The drug is suitable for the treatment of hypertension in diabetics with diabetic nephropathy - the defeat of blood vessels, glomeruli, renal tubules due to a metabolic disorder caused by diabetes.

Pros	Cons
Strong and persistent antihypertensive effect	More expensive drug compared with, for example, atenolol
Good tolerability with minimal or no side effects	Adverse effects: headache, dizziness, heart rhythm disturbance, dryness and nasal congestion, unreasonable weakness. Frequency of occurrence of effects is 1%, sometimes slightly more
Convenience of reception( only once a day with a gradual increase in the dose from 50 mg to 100 mg per day until stable stabilization of A / D level)

What are its analogues:

Valsartan, Eprosartan, Telmisartan are preparations from the same group, but more productive are Losartan and its analogues. Clinical experience has shown its high efficacy in eliminating elevated A / D, even in patients with complicated form of hypertension.

Lisinopril

Refers to the ACE inhibitor group. Antihypertensive effect is observed as early as 1 hour after taking the desired dose, increases in the next 6 hours to a maximum and persists for 24 hours. It is a drug with a long-term accumulation effect. The daily dosage is from 5 to 40 mg, taken once a day in the morning. In the treatment of hypertension, patients who undergo a pressure reduction are noted from the first days of admission.

Action	Possible side effects
Steadily maintains A / D level at normal values ​​	Dry cough
Increases myocardial tolerance to loads in heart failure	Dryness in the oral cavity
Prevents the progression of myocardial enlargement and an increase in the volume of left ventricular heart chambers in patients with severe formhypertension or post-infarction	Lowering A / D below normal
Well suited for treating high blood pressure in people with heart failureatochnostyu, diabetes( diabetic nephropathy), heart attack, without a history of hypotension
Sweating Dizziness

analogues List:

• Diroton,
• Renipril,
• Lipri,
• Lizinovel,
• Dapril,
• Lizakard,
• Lizinoton,
• Sinopril,
• Lizigamma.

Renipril GT

This is an effective combined preparation consisting of enalapril maleate and hydrochlorothiazide. In combination, these components have a more pronounced hypotensive effect than each individually. The pressure decreases gently and without loss of potassium by the body.

Advantages	Contraindications	High efficacy	Allergy to active ingredients
Good tolerability of most hypertensive patients	Pregnancy
Maximum concentration of the drug in the blood is reached after 2 hours and persists throughout the day	Primary hyperaldosteronism
Addison's disease
Regression of hypertrophy with unloading of the left ventricle of the heart	Stenosis of the renal arteries

What are the analogues of the agent:

Captopril

Perhaps the most common drug from the group of ACE inhibitors. It is intended for emergency help with the purpose of arresting hypertensive crisis. For prolonged treatment is undesirable, especially in elderly people with atherosclerosis of cerebral vessels, because it can provoke a sharp decrease in pressure with loss of consciousness. Can be administered along with other hypertensive and nootropic drugs, but under strict A / D control.

Pros	Cons
quickly normalized A / D	frequent dosing( up to 4 times / day)
improves blood circulation of the heart muscle during ischemia	Contraindications: aortic stenosis, narrowing of the mitral valve, kidney transplantation, breastfeeding, cardiomyopathy.
Reduces platelet aggregation - gluing blood cells to form thrombus	Undesirable side effects: dizziness, rapid heartbeat, orthostatic hypotension, increased transaminase in blood, etc.
With prolonged use, it can reduce the severity of myocardial hypertrophy	Use with caution in diseaseskidney, systemic autoimmune diseases
Cheapness

The list of analogues:

• Kopoten,
• Kaptopres,
• Alkadil,
• Katopil,
• Blokordil,
• Captopril AKOS,
• Angiopril,
• Rylakton,
• Capofarm.

Arifon-retard( indopamide)

Diuretic and hypotensive agent from the group of sulfonamide derivatives. In complex therapy, the treatment of arterial hypertension is used in minimal doses that do not exert a pronounced diuretic effect, but stabilize the pressure during the day. Therefore, when it is taken, it is not worth waiting for an increase in diuresis, it is appointed to lower the pressure.

Advantages of	Contraindications and special instructions
Convenience of use( once a day in the morning before meals)	Prohibited with hypokalemia, severe renal failure or severe liver dysfunction, allergic to active substance
One of the safest means of high blood pressure	Not recommended for people with lactose intolerance
Harmless to people with endocrine disorders( diabetes, obesity), because it does not affect lipid and blood glucose levels
Has a minimum of side effects and is well tolerated by virtually all patients.
Reduces left ventricular hypertrophy
Reasonable price

Analogues:

Veroshpiron

Potassium-sparing diuretic. Take from 1 to 4 times a day courses. Has a pronounced diuretic effect, while not removing the potassium from the body, which is important for the normal operation of the heart. They are used only in combined therapy for the treatment of arterial hypertension. With respect to the prescribed dose, the doctor does not cause side effects, with a rare exception. Long-term treatment in large doses( more than 100 mg / day) can lead to hormonal disorders in women and impotence in men.

Combined drugs against hypertension

To achieve the maximum antihypertensive effect and convenient reception, combined preparations are developed, consisting of several optimally selected components. These are:

• Noliprel( indopamide + perindopril arginine).
• Aritel plus( bisoprolol + hydrochlorothiazide).
• Exforge( valsartan + amlodipine).
• Renipril GT( enalapril maleate + hydrochlorothiazide).
• Lorista N or Lopaz plus( losartan + hydrochlorothiazide).
• Tonorm( triamterene + hydrochlorothiazide).
• Enap-H( hydrochlorothiazide + enalapril) and others.

The combined use of several drugs against increased pressure

Combination therapy is the most effective in the treatment of hypertension. To achieve persistent positive results, simultaneous reception of 2-3 drugs is mandatory from different pharmacological groups.

As combinedly taking pills from high blood pressure:

Therapeutic	combination preparations
Diuretic + beta blocker	chlorthalidone + atenolol hydrochlorothiazide + bisoprolol
ACE inhibitor + diuretic	Hydrochlorothiazide + captopril Indopamid + perindopril
Diuretic + Sartan	Losartan + hydrochlorothiazide Valsartan + hydrochlorothiazide
β-blocker + calcium channel blocker from the dihydropyridine group	Metoprolol + felodipine
ACE inhibitor + ancalcium agonist	Amlodipine + benazepril Enalapril + diltiazem

Summary of

Tablets from high blood pressure are large. With hypertension of 2 and 3 degrees, patients are forced to take medication at all times to keep their blood pressure normal. For this purpose, combined therapy is preferred, which achieves a stable antihypertensive effect without hypertensive crises. Prescribe any drug from the pressure should only the doctor. Before making a choice, he will take into account all the features and nuances( age, the presence of concomitant diseases, the stage of hypertension, etc.) and only then select a combination of drugs.

For each patient an individual treatment regimen is prepared, which he must adhere to and regularly monitor his A / D.If the effectiveness of the prescribed treatment is inadequate, you need to contact the doctor again to adjust the dosages or replace the drug with another. Self-administration of medications, based on the responses of neighbors or acquaintances, most often not only does not help, but also leads to the progression of hypertension and the development of complications.