Orthofen: instructions for the use of injections and gel

Instructions for the use of injections Orthofen

Intramuscular administration of drugsis considered an emergency and effective method of treatmentdue to rapid and uniform absorption of the active substance.

The use of this method of therapy is especially important for the relief of inflammatory foci and in the pain syndrome with which Orthofen's prizes are productively combated.

The direction of the drug

Orthofen -medicinal product based on the active substance diclofenac. The drug has a strong anti-inflammatory effect for the affected muscles and joints, lowers the overall low-grade and febrile temperature, reducing the hyperthermia of the affected area.

Due to the inhibition of certain receptors and prostaglandins in the focus of inflammation, the analgesic properties of diclofenac are realized.

Forms of implementation

The most effective and fast-acting form of Orthofen release is injection solution, more often produced by Russian pharmaceutical companies "Moshimfarmpreparaty na NA.

Semashko "and" Biochemist "for 10 ampoules in a cardboard package. Each ampoule contains 25 mg of diclofenac sodium.

The price fluctuates around 44 rubles per package for the intramuscular injection of Moskhimpharmpreparaty and 34 rubles for Biokhimik.

Since the use of painful injections is not always justified,The pharmaceutical market also offers other forms of output- ointments 2%, gels 5% and tablets, 25 mg of active ingredient.

Often the treatment regimen is such that in the acute period injections of the drug are prescribed, and then - tablets for a long time to complete cure under the control of biochemical indicators.

Application Scheme

A solution of diclofenacis administered exclusively by intramuscular injectionin a dosage of not more than 75 mg at a time.

It should be noted that Orthofen in ampoules can be used no longer than two consecutive days, with the difference between injections should exceed 12 hours.

The injections are prescribed solely for the relief of acute pain or inflammation, followed by a transition to the oral form of the drug.

Indications for use

Orthophenehas proved itself in the treatment of acute inflammatory processes of the musculoskeletal system, including in the defeat of muscles, joints and bones. The injections can be shown with an aggravation of the following chronic diseases:

• neuralgic amyotrophy;
• ostearthrosis;
• Bechterew's disease (spondylitis);
• radiculitis;
• rheumatism;
• various types of arthritis (with psoriatic, gouty, rheumatoid, with Reiter's disease)
• myalgia;
• myositis;
• neuralgia of different genesis;
• lumbago;
• arthralgia.

Meanscan be used for analgesiaafter surgical operations on the locomotor apparatus. There are also positive reviews about the use of gynecological and otolaryngological interventions, oncology, severe headache and toothache.

Application for analgesia is possible with adnexitis, otitis, pharyngitis.

Contraindications

Before using ampoulesit is necessary to familiarize with the instruction on applicationto clarify the updated version of contraindications. At this time, the drug is not used when:

• individual intolerance to diclofenac;
• "Aspirin asthma
• gastrointestinal ulcerative lesions;
• hemophilia and other serious hemopoiesis disorders.

Children under the age of 6 and women in the third trimester of pregnancy do not receive medication.

special instructions

Impaired kidney and liver function

Disorders in the liver and kidneysAre not direct contraindications to the use, but it is necessary to evaluate the biochemical profile of the patient before prescribing the medication in people with a history of this kind.

Pregnancy, lactation, children and the elderly

Clinical studies have not revealed embryotoxicity and teratogenicity of diclofenac, but due to suppression of prostaglandin activity in the 3 trimester of gestation, this medication is not prescribed. Also, the drug is not used in children under 6 years of age.

In nursing women and the elderly, the drug is administered with caution, but not prohibited.

Overdose, toxicity and side effects

The introduction of diclofenac into the gluteus muscle may be painful, so it is permissible to use novocaine or lidocaine to reduce soreness at the injection site.

Has hepatotoxicity, therefore it is necessary to carry out a study of liver samples and exclude the side effects inherent in the progress of liver and kidney diseases, including nausea, vomiting, icterus of cutaneous cover and itching. In rare cases - more often with oral use - ulcerative lesions occur gastrointestinal tract, accompanied by discomfort and painful sensations and frustration digestion.

Overdose is possible with drug consumptionmore than 150 mgper day.

Orthophene in doses exceeding therapeutic, leads to acute renal and hepatic insufficiency.

Treatment is symptomatic and aimed at reducing intoxication.

Interaction

With other medicines

Incompatible (due to increased intoxication and the appearance of undesirable effects) The action of which is suppressedThe effect of which is intensified

NSAIDs	Antihypertensive drugs	Digoxin
Fluoroquinolones	Diuretics	Lithium, potassium-containing
Glucocorticosteroids	Methotrexate
Hypoglycemic agents	Morphine
Anticoagulants of indirect action	Cyclosporin

Acetylsalicylic acid leads to increased side effects of diclofenac, but reduces its basic properties.

With alcohol

For the period of treatmentfrom alcohol intake is better to refuse.

Storage and dispensing from pharmacies

Prescription leave. Storage is not more than two years in a dark place at a temperature of 0 to 25 degrees.

Analogues

Based on the active ingredient, the following preparations can be considered analogues, which differ from the manufacturer, the concentration of the basic substance and the price:

• Voltaren ~ 219 rubles;
• Diclofenac ~ 31 rubles;
• Diklak ~ 59 rubles;
• Diklogen ~ 14 rubles;
• Diclonat ~ 85 rubles.

Forms of release of medicines are various as well as Orthofen.

Reviews

According to reviews, Orthofen is well tolerated by virtually all groups of patients who have no contraindications to the use of this drug.

The active substance has a strong and rapid analgesic effect.

However, many are confused by the ban on frequent use of injections and their soreness in the place of introduction.

Orthofen is a good remedy for emergency use, successfully used for inflammatory and degenerative changes in the musculoskeletal system.

The use of medicines, taking into account its properties and all contraindications, reduces the risk of adverse side effects.How to forget about joint and spinal pain?

• Does pain limit your movements and full life?
• Are you worried about discomfort, crunching and systematic pain?
• Perhaps you have tried a bunch of medicines, creams and ointments?

A source: http://zdorovya-spine.ru/preparaty-i-lekarstva/ortofen-ukoly.html

Orthofen injections: instructions for use

Orthofen refers to non-steroidal drugs that inhibit the inflammatory processes in the body.

Composition, form of release

Medication is produced in the form of a solution in ampoules intended for intramuscular injections. In 1 ml of the drug contains 25 mg of the active compound in the form of diclofenac.

Each ampoule has a volume of 5 ml with contents of 3 ml. Packed ampoules in a package of 10 or 5 pieces.

Pharmacological properties

The drug is aimed at eliminating painful sensations and suppressing inflammatory processes. Also, the main component has a moderate antipyretic effect.

The essence of the drug is based on the fact that the activity of cyclooxygenase, which is the main enzyme in the metabolism of arachidonic acid (the progenitor of prostaglandin), is suppressed.

Also, the drug suppresses the production of proteoglycan, which is contained in the cartilaginous tissue.

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In patients suffering from rheumatic diseases, after treatment, painful sensations in the joints during movement and in a calm position are reduced.

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Orthofen therapy reduces the feeling of stiffness in the morning and swelling around the joints, thereby helping to increase the amount of physical activity.

And also the medicine reduces painful sensations after surgical interventions, after traumas and at edemas accompanied by inflammatory process.

The main component inhibits the process of platelet aggregation. Long-term use leads to a desensitizing effect.

Indications for use

Medication is prescribed for the following diseases:

• Expressed painful sensations in infectious diseases of the nose, throat and ear, accompanied by an inflammatory process. The drug may be prescribed as part of a comprehensive treatment;
• The febrile syndrome;
• Painful sensations arising after traumatic wounds, accompanied by an inflammatory process;
• Painful sensations after surgical interventions;
• Colic renal;
• Migraine;
• Bursitis;
• Degenerative diseases of the musculoskeletal system;
• Tendovaginitis;
• Diseases of the musculoskeletal system accompanied by an inflammatory process: ankylosing spondylitis, rheumatoid arthritis, juvenile or psoriatic arthritis in the chronic stage;
• Myalgia, neuralgia;
• Arthritis gouty, rheumatic changes in soft tissues;
• Sciatica, lumbago.
• Increased blood pressure;
• Headache;
• Diarrhea;
• Nausea;
• Painful sensations in the abdomen;
• Allergic manifestations on the skin;
• Dizziness;
• Vomiting;
• Belching.
• High susceptibility to any component of the drug;
• Pregnancy (last trimester);
• Asthma bronchial ("aspirin" form);
• Ulcer in the duodenum and stomach;
• Children younger than 6 years;
• Exacerbation of diseases of the intestine with the presence of inflammatory processes;
• Negative changes in hematopoiesis of unspecified origin.

Dosing regimen

The solution is intended for intramuscular injections. Usually appoint 1 injection per day, which is done in the gluteus muscle (uppermost quadrant). In severe disease, 2 injections per day are prescribed.

Overdose

In case of application of the drug in a dosage exceeding the therapeutic norm, the following symptoms may appear: negative changes in the work of the kidneys and liver, disturbances in work digestive tract (bleeding, vomiting, pain in the abdomen, nausea), myoclonic spasms, hyperventilation, dizziness, negative changes in consciousness, headache.

In the case of an overdose, treatment is performed aimed at suppressing undesirable symptoms (respiratory depression, irritation digestive tract, seizures, changes in kidney function, increased blood pressure), prescribe an activated coal. Conduction of hemodialysis and forced diuresis does not have a significant effect.

Drug Interactions

Parallel administration of the drug Orthofen and drugs with lithium content, derivatives of quinolone, antidiabetic means of the oral form, anticoagulants of indirect and digoxin can lead to increase in concentration in blood the latter.

Joint administration of cyclosporine and methotrexate increases their toxic effect.

Simultaneous reception of potassium-sparing diuretics increases the likelihood of hyperkalemia, and also reduces the therapeutic effect of diuretics.

Parallel intake of acetylsalicylic acid leads to a decrease in the concentration of Orthofen in the blood.

Lactation, pregnancy

The use of medication by patients during pregnancy (especially in the last trimester) is contraindicated. If a lactating woman should undergo treatment with Orthofen, breastfeeding should be stopped.

Side effects

The use of a medicament may provoke the following undesirable manifestations:

Contraindications

Medication can not be administered in the following situations:

special instructions

It is desirable to use the medication in the lowest effective dosage for the shortest period of time, as otherwise the likelihood of negative changes in the digestive tract.

Patients suffering from renal or heart failure, elderly patients, and also taking diuretic medicines should be prescribed Orthofen with more caution.

Such patients are advisable during the treatment to monitor the functional work of the kidneys.

Use of the drug Orthophene can cause the development of hyperkalemia.

The use of medication negatively affects fertility, and therefore its use is not recommended for patients who want to become pregnant.

Since the speed of motor and mental response decreases during therapy, it is desirable refuse to drive cars and occupations that require high attention and quick response.

Orthofen in ampoules price

The average cost of Orthofen in ampoules No. 10 in Moscow is 41 rubles.

Analogues of injections Orthofen

Analogues of the drug Orthofen on pharmacological properties are: Flotac, Feloran, Tabuk-Di, Sanfinak, Revmavek, Orthoflex, Naklofen, Naklof, Dorosan, Diphene, Diclofenac, Diclonate, Diklogen, Voltaren.

Terms and conditions of storage

The medicament is stored at a temperature of not more than 25 gr C in a dark place, remote from small children. The medicine is allowed to be used within 2 years from the moment of its release.

A source: http://bezboleznej.ru/ortofen-ukoly

What helps with Orthofen injections and how to apply them?

Orthofen - injections for intramuscular injection, used in the complex treatment of diseases of the musculoskeletal system and some other pathologies in adult patients. The drug is produced in Russia. Its manufacturer is the pharmaceutical company "Moshimfarmpreparaty im. N. A. Semashko ».

Orthofen belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs).

Like most drugs, it has contraindications and can have a negative impact on the human body.

To achieve recovery with Orthofen, it is necessary to apply it only on the recommendation of a doctor, strictly following all prescriptions.

Active substance and effect on the body

If the doctor prescribed injections, Orthofen is on sale in the form of a colorless transparent liquid - a solution for injections, poured into glass ampoules.

Inside each tank is 3 ml of medicine. In one cardboard package 5 or 10 ampoules with a solution and medical annotation from the manufacturer are enclosed.

The drug for intramuscular administration Orthofen is based on diclofenac, a phenylacetic acid derivative with a significant analgesic, anti-inflammatory and antipyretic effect. The active ingredient in 1 ml of the drug solution is 25 mg.

The therapeutic effect of diclofenac is due to its ability to inhibit the biosynthesis of prostaglandins - lipid physiologically active substances that promote the development in the human body of the inflammatory process, pain syndrome and heat. Diclofenac has no effect on the synthesis of proteoglycans of cartilaginous tissue. In the treatment of rheumatic pathologies, it effectively eliminates pain and swelling in the joints, improves their mobility. The use of diclofenac in trauma and in the postoperative period helps quickly to stop painful manifestations and reduce swelling in the focus of inflammation.

When a remedy is assigned

Indications for the use of Orthophene are spread to diseases accompanied by pain syndrome of varying intensity, inflammation and fever. The medicinal solution is used in complex therapy:

• arthritis of various genesis (gouty, rheumatoid, psoriatic, etc.);
• rheumatic diseases of the periarticular soft tissues (bursitis, tenosynovitis, tendonitis, fasciitis, aponeurosis, enthesopathies);
• ankylosing spondylitis;
• osteochondrosis;
• deforming osteoarthrosis;
• lumbago;
• neuralgias of the sciatic nerve;
• myalgia;
• post-traumatic and post-operative pain;
• migraine;
• renal colic;
• proctitis;
• inflammation of the appendages and primary algodismenorea (in women);
• inflammatory diseases of the ENT organs (otitis media, pharyngitis, etc.);
• fever.

The medical instruction recommends injecting Orthophen injection for intramuscular injection into the buttock area. Dosage and duration of use of the drug are determined by the physician, taking into account the clinical picture.

The injections with diclofenac are painful enough. To minimize discomfort from them, the drug should be warmed to body temperature before use.

For this, an unopened ampoule with the contents is recommended to be held in warm hands for 2-3 minutes.

Cautions for use

Before starting the use of Orthofen, the patient should familiarize himself with the list of contraindications to it. The drug is prohibited for people suffering from:

• individual intolerance to diclofenac or other NSAIDs;
• peptic ulcer of stomach and duodenum;
• tendency to internal bleeding;
• bronchial asthma (in the presence of hypersensitivity to acetylsalicylic acid);
• blood diseases.

Contraindications to the use of Orthophene also apply to women in the third trimester of pregnancy, breast-feeding mothers and children under the age of 15 years.

Caution in the use of solution for injection should be shown in severe cardiac pathologies, edema, renal or hepatic insufficiency, hepatic porphyria, hypertension, diabetes, diverticulosis of the colon, alcoholic dependencies. Women who are in the first and second trimesters of pregnancy, and people over 65 years to prevent the undesirable consequences of treatment, use Orthofen is necessary under the supervision of a doctor.

Undesirable symptoms from the drug

Treatment with diclofenac does not always go away without the occurrence of side effects.

This chemical component can have a negative effect on various organs and systems in the human body, cause a number of undesirable effects.

Common adverse reactions to Orthophen solution include:

• disorders in the work of the digestive tract (nausea, vomiting, increased gas formation in the intestines, constipation, diarrhea);
• the formation of ulcers on the mucous membrane of the stomach and duodenum;
• gastrointestinal bleeding;
• nephritis;
• acute renal insufficiency;
• drug-induced hepatitis;
• abnormal liver function;
• violation of coordination of movements;
• headache;
• dizziness;
• problems with sleep;
• increased blood pressure;
• peripheral edema;
• local reactions in the area of ​​injection (compaction, burning, itching, hyperemia);
• systemic allergic manifestations (rash on the skin, hives, anaphylactic shock);
• convulsions;
• bronchospasm;
• alopecia;
• blood diseases (anemia, agranulocytosis, thrombocytopenia);
• decreased visual acuity.

The described side effects are most often observed in people receiving orthotaxin injections in large doses or for a long time.

To avoid the occurrence of undesirable effects from treatment, use Orthofen in minimal effective doses for a short time.

Combination with other means

Intramuscular injections of Orthophene should not be combined with the use of glucocorticosteroid agents, anticoagulants of indirect action, diuretics, oral hypoglycemic drugs, digoxin, cyclosporine, methotrexate, acetylsalicylic acid, group antibiotics quinolones.

Cost and analogy

Orthofen is an inexpensive medication that can be bought in many domestic pharmacies by prescription. The average package price (10 ampoules) is 42 rubles.

In the absence of the drug on sale, the pharmacist can offer the buyer its analogues - Diclofenac, Diclofen and Voltaren. These agents are also produced as a solution for intramuscular administration and have the same recommendations for use as Orthofen.

Response and storage requirements

Patients who managed to experience the action of Orthopen from their own experience leave positive comments about him.

The drug solution quickly (during the 15-25 minutes after the injection) stops the pain syndrome, stops the progression of the inflammatory process and normalizes the body temperature.

Some patients are alarmed by the large number of side effects from the drug, however, using it in accordance with the doctor's testimony, the deterioration of the state of health is extremely rare.

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The drug Orthofen in the form of a solution for injection should be stored in the original packaging, placing in a dark, dry and cool place. The medicine should not be exposed to low temperatures (up to + 5 ° C) or extremely high (above + 30 ° C) temperatures. The expiration date is 2 years from the date of issue.

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A source: https://OrtoCure.ru/preparaty/ortofen-ampuly.html

"Orthofen" injections. Instructions for use. Side effects :

If you feel unbearable pain associated with rheumatism, arthrosis, osteochondrosis, muscle strain or, for example, suffer after surgery, the doctor may prescribe you Orthofen as a solution for injections.

The injections with this drug quickly and effectively relieve the patient of the pain of different etiologies. Today we learn when a doctor can prescribe this medication, in what dosage it should be used, and also the opinions of patients about injections using this medication.

Pharmacodynamics

"Orthofen" is a non-steroid drug that has anti-inflammatory, analgesic and antipyretic effects. The advantage of this drug over other similar drugs is a less pronounced irritant effect on the mucous membrane of the stomach and intestines.

In what cases are injections with a solution of "orthophene" applied?

Indications for use of the drug as injections can be as follows:

• Inflammatory and degenerative forms of rheumatic diseases (radiculitis, osteochondrosis, rheumatism).
• Acute attacks of gout.
• Otitis and pharyngotongzillitis, accompanied by pain.
• Treatment after dental and orthopedic interventions, when the patient has a pain syndrome.
• Stretchings and bruises of muscles, ligaments, joints.
• Severe pain in the spine after surgery or trauma.
• Diseases of the joints (arthritis, arthrosis).
• Gynecological ailments, accompanied by inflammation and pain.

The drug "Orthofen injections. Instructions for use

Injections are done intramuscularly, but intravenous or subcutaneous drug administration is prohibited. The frequency of manipulation is every other day.

The maximum daily dose is 5 injections of 5 ml of the drug. The duration of therapy should not exceed 5 days.

After their expiration, the patient is transferred to other forms of administration of this drug (tablets or ointment).

To relieve the unpleasant sensations, you must immediately before the injection hold a bottle of medicine in the palm of your hand, so that the solution is slightly warmed.

This will remove the pain syndrome, as well as enhance the anti-inflammatory effect of the drug.

Ordinarily, injections of Orthofen are made in the upper outer square of the buttock.

However, in some cases (if it is impossible to put bruises in the right place and put the injection), it is possible to stab in the outer part of the thigh.

Intravenous drug administration is strictly prohibited, as it can lead to death.

Adverse Events

If the "Orthofen" shots are done correctly, with all the instructions given in the instruction (holding the necessary dosage, as well as all the rules necessary for the injection), then there are no undesirable effects will be. However, if the patient does not adhere to the desired treatment regimen, then side effects can manifest. So, the undesirable effects are:

• Headache, dizziness.
• Nausea, vomiting.
• Flatulence.
• Loss of appetite.
• Rashes over the body.
• Depression.
• Drowsiness or, on the contrary, insomnia, caused by the appearance of nightmares.
• Irritability.
• Problems with memory.
• Tremor (when the hands are shaking for no reason).
• Deterioration of hearing, the appearance of ringing in the ears.
• Visual impairment (blurred image).
• Heart failure, chest pain.
• A heart attack.
• Stomatitis.
• Violation of the liver (hepatitis, jaundice, etc.).

Contraindications

It is forbidden to use the drug "Orthofen

• Pregnant women, as well as nursing mothers.
• Children up to 8 years.
• Patients who have problems with the gastrointestinal tract, especially if there is a history of stomach ulcers.
• Patients with severe impairment of kidney and liver function.
• Patients who have hypersensitivity to aspirin or other components of the drug.

Storage conditions. Manufacturer country

You need to save the medicine in a dark cool place.

Also, it should be kept away from children, so that they do not reach it inadvertently, and do not drink, because this can lead to irreversible consequences.

The shelf life of Orthofen solution is 24 months. Open the medicine bottle should be used immediately, without leaving it for later.

A drug is produced in the Russian Federation.

Than it is possible to replace?

Now it is easy to find drugs that would replace the solution of "Orthofen". Analogs of this drug are sold at each pharmacy.

Therefore, if there is no medicine "Orthofen" in the form of injections, and they are just shown to the patient, then you can replace the drug with another. Similar solutions are such solutions as Diclofenac, Diclac, Voltaren, and others.

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However, often, if there is no medicine "Orthofen the doctor replaces the drug "Diclofenac". After all, in essence both medicines are the same. At the heart of the drug "Orthofen" the active substance is just diclofenac sodium.

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Therefore, the difference between these means is only in name and value. The drug "Diclofenac" is made abroad, so its price is higher than that of its Russian counterpart.

Cost

The drug "Orthofen the price of which, by the way, is available to any person, is a fairly common tool, so you can buy it at any pharmacy. So, for 10 ampoules of the drug you only need to pay about 40 rubles.

For comparison, the well-known medication "Diclofenac" in the form of a solution is sold at a price of 60 rubles. And this cost for 5 ampoules, and if you take 10 pieces, then it will be 120 rubles. The difference is 80 rubles. That is, for 120 rubles you can buy 3 packages of the drug "Orthofen".

Apparently, this tool is much cheaper than its famous counterpart.

Positive responses of patients

The drug "Orthofen" reviews from patients receives mostly flattering. So, patients like that the drug effectively copes with the pain of various etiologies, with inflammatory diseases.

This is a universal tool that helps whole families.

After all, there are often reviews of people, where they write that the solution of "Orthofen" was used for treatment elderly people, when it was necessary to remove severe pain in the back, and also helped young women and to men.

Indeed, there are many laudatory reviews from people in favor of the manufacturer for the fact that it does not increase the cost of the medication. The price of a solution for injections is available for any citizen of Russia and neighboring countries. That is why the drug is affordable and widely distributed.

Negative responses of patients

Unfortunately, the Orthofen solution reviews are not only flattering, but also disapproving. Some people note that this remedy had a negative impact on their health.

They began to have problems with the gastrointestinal tract, irritability, memory problems. And some patients even note that the drug "Orthofen" is addictive.

To prevent this from happening, and the person has kept his health for many more years, it is necessary to use the remedy only for the doctor's prescription. And in fact often patients to themselves harm and apply nyxes, when and as they want.

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Especially clearly this can be traced in the event that a person became ill, at home there was someone from family members, who can do injections and, in fact, the patient was administered a medicine without prescriptions the doctors. This is strictly prohibited.

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The patient, of course, was lucky that there is a person at home who can inject. However, on the other hand, one can not assume such responsibility and conduct injections without prescribing a doctor. After all, it is from here that side effects may also emerge, of which the patients themselves write.

It is also forbidden to give injections longer than 5 consecutive days, because this can negatively affect the patient's state of health. Any medicine, including the drug "Orthofen should be used competently, according to the doctor's prescription. And then there will be no negative feedback.

Despite the fact that injections of "Orthofen" can be quite painful, yet injections with this drug are often used to relieve pain of various etiologies.

This drug of Russian production receives mostly positive reviews from patients.

And this is not surprising, because for its small cost the medicine brings an excellent effect: the patients quickly have pain, they feel great already on the third day after the beginning of therapy.

A source: https://www.syl.ru/article/207548/new_ukolyi-ortofen-instruktsiya-po-primeneniyu-pobochnyie-effektyi

What helps Orthofen. Instructions for the use of tablets and ointments

A non-steroidal anti-inflammatory drug is Orthofen.

What helps this medicine? The product is isolated from phenylacetic acid, it has a moderate antipyretic, significant anti-inflammatory and analgesic effect.

Ointment and tablets "Orthofen" instruction for use recommends the use of migraine, pain in the spine, gout.

Forms and composition

Issue the following forms of medicament:

1. Gel for external use 5%.
2. Orthofen tablets, coated with 25 mg.
3. Ointment for external use 2% (sometimes mistakenly called cream or gel).
4. Solution for intramuscular injection (injections in ampoules for injection).

The active substance of the drug is diclofenac sodium.

• The gel contains an active ingredient in the amount of 5 g per 100 g of tube.
• On 1 g of ointment is 20 mg of the active ingredient.
• In 1 ml of the solution contains 25 mg of active substance.
• The composition of 1 tablet contains 25 mg of diclofenac sodium.

Pharmacological properties

The active substance is diclofenac. Due to its presence in the drug "Orthofen the instruction for use explains this, has antipyretic, analgesic and anti-inflammatory effects. The main component is a phenylacetic acid derivative.

Its mechanism of action is directed at non-selective inhibition of cyclooxygenases, a decrease in the concentration of prostaglandins in the inflammatory focus, a violation of the metabolism of arachidonic acid. The drug has an additional antiaggregant activity.

Injections, ointment, tablets "Orthofen what helps the medicine

Indications for the use of injections and tablets include:

• pain syndrome in infectious and inflammatory diseases of ENT organs;
• pain in the spine;
• arthralgia;
• colic (biliary and renal);
• myalgia;
• pain syndrome with adnexitis, proctitis;
• migraine;
• degenerative and chronic inflammatory diseases of the musculoskeletal system (osteochondrosis, osteoarthritis, periarthropathies);
• post-traumatic inflammation of soft tissues and musculoskeletal system (stretching, bruising);
• pain syndrome with gout;
• pain syndrome and inflammation after surgery and trauma;
• articular syndrome (rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout);
• neuralgia;
• algodismenorea.

Why is Orthofen appointed yet? For topical application, an ointment or gel is prescribed:

• post-traumatic inflammatory process with penetrating and non-penetrating injuries of the eyeball;
• inhibition of miosis during surgery for cataract;
• inflammatory processes of the eye of non-infectious nature;
• prevention of cystoid macular edema associated with removal and implantation of the lens.

The drug "Orthofen instructions for use, dosing

The medication is prescribed in the following dosages:

• for the treatment of various acute inflammatory processes, use "Orthofen" injections, which should be administered intramuscularly once a day for 3-5 days;
• supporting therapy is carried out with the help of tablets, which are applied 3-4 times a day at intervals of 4-6 hours.

Rapid absorption of tablets from the digestive tract allows the use of this drug for the treatment of acute conditions in which rapid action of the drug is necessary (for 30 minutes).

Also, the drug is indicated for post-traumatic pain, since diclofenac, which is part of it, quickly alleviates pain during movement and sudden pain. Also, diclofenac reduces puffiness in the area of ​​trauma or injury and reduces swelling in inflammation.

Instructions for use ointments

Ointment "Orthofen" is indicated for use in similar conditions, but it acts more gently, directly affecting the problem area, quickly relieving pain in the foci of inflammation. In the instructions to "Orthofen the simultaneous use of tablets, ointments and injections of this drug is prohibited, since this can cause increased side effects.

It is also not recommended to use this drug simultaneously with other NSAIDs. Depending on the severity of the patient's condition and the presence of a particular disease, an individual dosage of the drug is selected.

For adults, the initial dose is 100-150 mg, in the treatment of diseases in mild form there is enough and 75-100 mg of the drug.

In any case, the daily dose of the drug should not exceed 150-200 mg, this dose is recommended to be divided into 3-4 doses.

The drug should be taken immediately after the manifestation of the first pain symptoms. The use of "Orthofen" is allowed for children from 8 years (with a body weight of more than 25 kg), they are prescribed a drug at a dosage of 25 mg per day. Children over 14 years of age are prescribed 1-2 mg per kilogram of body weight.

Side effects

Tablets and injections can cause:

• Local reactions: with the / m introduction possible burning at the injection site; in some cases - the formation of an abscess and / or infiltrate, necrosis of adipose tissue.
• Digestive system: discomfort and pain in the epigastrium, nausea, vomiting, constipation, diarrhea, flatulence, anorexia; in some cases - erosion, bleeding, ulcerative lesions and perforation of the gastrointestinal tract; rarely - violation function of the liver.
• Urinary system: rarely - impaired renal function; possibly - edema (in patients with a predisposition).
• Allergic reactions: skin itch, rash.
• Nervous system: dizziness, agitation, headache, insomnia, a feeling of fatigue, irritability; rarely - paresthesia, diplopia, blurred vision, tinnitus, convulsions, tremor, depression, mental violations.
• The system of hematopoiesis: rarely - anemia, thrombocytopenia, leukopenia, agranulocytosis.
• Dermatological reactions: rarely - hair loss.

Ointment for external use 2%, gel "Orthofen" 5% can provoke:

• Rarely: burning, itching, rash, redness;
• Perhaps: with prolonged use and / or application to large areas of the body - the emergence of systemic side effects against the background of the resorptive effect of diclofenac.

Contraindications

According to the instructions, "Orthofen" does not apply when:

• "Aspirin" asthma;
• intolerance to diclofenac;
• disorders of the blood coagulation system;
• hematopoiesis
• "Aspirin" triad (recurrent polyposis of nose, paranasal sinuses is combined with bronchial asthma and intolerance to acetylsalicylic acid, medicines of pyrazolone series);
• pregnancy;
• erosive and ulcerative lesions in the digestive tract;
• hemophilia;
• thoracic feeding;
• anemia;
• leukopenia;
• tendency to bleeding;
• lengthening the period of bleeding;
• children up to the age of six.

With caution appoint "Orthofen with puffiness, alcoholism, renal and hepatic insufficiency, arterial hypertension, erosive and ulcerative lesions of the digestive system, with a decompensated form of chronic heart failure, with anemia, bronchial asthma, diabetes, postoperative period, with acute induced hepatic porphyria and elderly patients age.

What are the analogues of Orthofen?

Complete analogs for the active substance:

1. Dicclore.
2. Revmavek.
3. Diklo-F.
4. Diclomax.
5. Diclofenacol.
6. Flotac.
7. Orthofer.
8. Diklak.
9. Believed.
10. Feloran retard.
11. Naklofen Duo.
12. Remetan.
13. Voltaren.
14. Diklovit.
15. Diklogen.
16. Redwood retard.
17. Sanfinak.
18. Diclonate.
19. Rapten Duo.
20. Tabuk-Dee.
21. Diklak Lipogel.
22. Rapent Rapid.
23. Naklof.
24. Orthophene injection,%.
25. Diclofen.
26. Diclonac.
27. Diklobene.
28. Diphene.
29. Diclomelan.
30. Diclorium.
31. Artrex.
32. Diclofenac Long.
33. SwissSchet.
34. Naklofen.
35. Orthoflex.
36. Dicluberl.
37. Diclofenac.
38. Voltaren Emulgel.
39. Feloran.
40. Dorosan.

Leave conditions and price

From pharmacies, the medicine is dispensed on prescription. The average price of Orthofen, tablets (Moscow), is 354 rubles. Ointment costs 69 rubles. In Minsk, pharmacies offer the drug for, white. rubles. In Kiev, the medicine costs 7 hryvnas, in Kazakhstan - 200 tenge.

Reviews

About ointments "Orthofen" testimonials testify in favor of this remedy. The medicine instantly anesthetizes and relieves inflammation in problem areas. Tablets quickly and effectively help relieve pain and inflammation, reduce temperature.

The drug is effective for otitis, bursitis, inflammation of the joints, well anesthetize with arthritis. Of the minuses, there is a bad effect on the stomach, which can lead to an ulcer. Also, the medicine has a large number of contraindications.

A source: http://OtchegoPomogaet.ru/ortofen-instrukciya-po-primeneniyu.html