Actyferrin

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Aktiferrin and Aktiferrin compositum refer to preparations containing iron.Active components of these drugs are iron sulfate heptahydrate and alpha-amino acid serine. Iron heptahydrate replenishes the deficiency of this mineral in the body, and the alpha-amino acid serine allows it to be more actively absorbed from the stomach into the systemic bloodstream.

When used, there is a rapid replacement of iron deficiency in the body, gradual regression of laboratory and clinical symptoms of anemia. The patient improves well-being, and weakness, fatigue, tachycardia, dizziness and dry skin gradually disappear.

On this page you will find all information about Actyferrin: the full instruction on the application for this medicine, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Aktiferrin. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Anti-anemic drug.

Conditions of leave from pharmacies

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The drug is released by prescription.

Price list

How much does Aktiferrin cost? The average price in pharmacies is at the level of240 rubles.

Form of release, composition and packaging

The drug is available in the form of capsules, syrup and drops.

  • The active substances in the capsules are iron sulfate monohydrate and serine. Auxiliary components are: yellow beeswax, lecithin, soybean oil, rapeseed oil.
  • Active ingredients of Actyferrin in the form of a syrup are iron sulfate heptahydrate and serine, and auxiliary: ascorbic acid, ethanol, invert sugar syrup, raspberry and cream flavors, purified water.

The composition of drops Aktiferrin, in addition to these auxiliary components, also includes potassium sorbate.

pharmachologic effect

Aktiferrin contains in its composition iron and amino acid serine, which improves its absorption and promotes the rapid replenishment of its deficiency.

For this reason, many positive responses Aktiferrin received, because due to its properties, the drug helps to quickly recover patients suffering from weakness due to lack of iron and increased fatigue. Also, the drug helps people suffering from tachycardia, frequent dizziness.

What helps Aktiferrin?

According to the instructions, Aktiferrin is used in cases when a person has iron deficiency, iron deficiency anemia, chronic gastritis, ulcer of the gastrointestinal tract. In addition, the drug is prescribed for neoplastic diseases, after resection of the stomach or patient-borne infections.

Actiferrin for children is recommended to be prescribed during the period of active growth, as well as during reduced immunity in case of infectious or neoplastic diseases.

Contraindications

Aktiferrin is contraindicated in the following cases:

  • With an overabundance of iron in the body, which is observed with hemolytic anemia, hemochromatosis.
  • In anemia, not associated with a lack of iron.
  • In the absence of lactase, intolerance to galactose or fructose, sugar-isomaltase deficiency and glucose-galactose impairment of absorption.
  • If the patient has an increased sensitivity to the main or auxiliary components of the drug.

To avoid an overdose, the drug should be used with caution with food supplements containing iron salts and diet products.

For patients suffering from gastrointestinal diseases, prior to prescribing the drug, to assess the estimated benefit from therapy with Actyferrin and correlate it with the risk of complications.

Pregnancy

Use during pregnancy and during lactation is possible if the potential benefit of therapy for the mother exceeds the possible risk to the fetus or infant.

Instructions for use

The instructions for use indicate that Actiferrin is recommended for adults and adolescents in the form of capsules, at the beginning of therapy - 1 capsule 2-3 times / day. With a poor tolerance of the drug, the dose is gradually reduced to the maximum tolerable. The duration of therapy (before the normalization of hemoglobin) is increased.

  • Children over 6 years of age Aktiferrin appoint 1 capsule / day.
  • Children older than 2 years are preferable to prescribe the drug in the form of a syrup. The daily dose is 5 ml / 12 kg of body weight. The average dose for preschool children is 5 ml 1-2 times / day; for children of school age - 5 ml 2-3 times / day.
  • Newborns and young children Actiferrin is administered in the form of drops. The daily dose is set at the rate of 5 drops / 1 kg of body weight; multiplicity of appointment - 2-3 times / day. The average dose for infants is 10-15 drops 3 times / day; for children of preschool age - 25-35 drops 3 times / day; for children of school age - 50 drops 3 times / day.

The drug is taken orally immediately before meals or during meals. Capsules are not chewed, washed down with enough water. Drops and syrup are taken with a small amount of liquid (fruit tea or water).

Treatment with the drug is continued for at least 8-12 weeks after achieving normal values ​​of serum iron and hemoglobin, appointing a maintenance dose.

Instructions for drops

Actyferrin in the form of drops can be prescribed even to newborn babies who were born before the term, with congenital pathologies of the digestive system or receiving from the first days of life an adapted milk formula. Dosage is calculated by 5 drops per 1 kg of the child's body weight.

For therapeutic purposes, Actyferrin is administered in the following dosages:

  • Newborn children - 10-15 drops three times a day;
  • Children of younger preschool age (from 1 to 3 years) - 25-30 drops three times a day;
  • Children of school age (from 7 to 12 years) - 50 drops three times a day.

The duration of the use of Aktiferrin is determined only by the doctor, based on the blood test and total the condition of the patient, however, in order to replenish the iron stores, drops should be taken for at least 2-3 months. During this period, the body usually replenishes the iron deficiency and creates certain of its reserves. After normalization of blood test results, the patient passes to a maintenance dose of the drug.

Side effects

Taking the drug can lead to the development of negative side reactions from various organs and body systems, they include:

  1. On the part of the digestive organs: bitterness in the mouth, poor appetite, constipation, flatulence, diarrhea and in rare cases vomiting, abdominal pain, nausea;
  2. Allergic reactions: rash, redness and itching of the skin, in rare cases anaphylaxis;
  3. From the side of the central nervous system: headaches and dizziness, in rare cases - irritability, weakness, in very rare cases - encephalopathy with epileptiform seizures;
  4. Others: sore throat, toothache, feeling of squeezing in the chest.

In most cases, the drug is well tolerated by patients. Side reactions from the digestive organs are eliminated by lowering the dosage.

Overdose

The highest probability of an overdose in children. Even with the reception of one gram there may be a threat to the life of the child, so the drug should be well hidden.

Symptoms of overdose are: nausea, diarrhea, vomiting, drowsiness, shock and collapse of blood vessels. After 5 hours after the onset of the first symptoms, there may be an improvement in the condition, but within 12-48 hours the clinical the picture can deteriorate significantly (shock, toxic hepatic insufficiency, coagulopathy, Chain-Stokes respiration).

Because of toxic hepatitis, jaundice may appear, there may be disturbances from the nervous system, up to the coma. If therapy was performed on time, the likelihood of a fatal outcome is significantly reduced.

  • First, you should wash the stomach with bicarbonate or phosphate p-am, then take milk and a raw egg.
  • Deferoxamine (1-2 grams) can be administered by intravenous drip. And one more injection the next day.
  • Clinically proven ineffectiveness of hemodialysis, it is possible to use peritoneal dialysis.
  • In very severe conditions, sodium dimercaptopropanesulfonate can be administered.

Reviews

The drug as a whole has good reviews. It is transferred well, side effects are infrequent. Many people like the relatively low cost and variety of dosage forms. Aktiferrin Compositum was much more approached, as it was better assimilated.

Reviews about Actiferrin for babies

The drug well raises the level of hemoglobin, the child becomes more active, the skin color improves. However, the side effects still arise, badly washed from clothes.

Analogues

Structural analogs for the active substance:

  • Aktiferrin compositum.

Analogues on the pharmacological group (drugs, stimulators of hematopoiesis):

  • Aranesp;
  • Argeferr;
  • Biofer;
  • Venofer;
  • Vitamin B12;
  • Hemofer;
  • Granogen;
  • Grazalva;
  • The iron fumarate;
  • Iron polymaltose;
  • CosmoFer;
  • Leukogen;
  • To the Leichest;
  • Maltofer;
  • Maltofer Foul;
  • Methyluracil;
  • Myelastra;
  • Mozobail;
  • Monofer;
  • Neutrostim;
  • Neostimium;
  • Unstable;
  • Panagen;
  • Pentoxyl;
  • The Revolade;
  • Sorbifer Durules;
  • Tardiferon;
  • Tevagrastim;
  • Totem;
  • Fenules 100;
  • Ferlatum;
  • Ferretab;
  • Ferrinate;
  • Ferrohematogen;
  • Ferronal;
  • Ferronat;
  • Ferroplex;
  • Ferrum Lek;
  • Filgrastim;
  • Fitin;
  • Folacin;
  • Folic acid;
  • Folic acid forte;
  • Heferol;
  • Ceruloplasmin;
  • Cyanocobalamin;
  • Epokrin;
  • Epomax;
  • Eralfon;
  • Erythropoietin;
  • Erythrostim.

Before using analogues, consult your doctor.

Terms and conditions of storage

The drug should be stored out of reach of children at a temperature of no higher than 25 ° C. Shelf life - 2 years.


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