Triderm

Triderm is a dermatological agent for external use.

The use of the drug is based only on the treatment of a disease obtained by a secondary infectious method. For preventive purposes, the agent is not used due to the intensive action of the active ingredients in the formulation. Effective in viral, fungal and bacterial infections, as well as in mixed genesis.

After applying the ointment or cream Triderm on the skin, the active ingredients of the drug are adsorbed into the skin, where they have a therapeutic effect. They are practically not absorbed into the systemic circulation.

Clinical and pharmacological group

The drug with antibacterial, antifungal and anti-inflammatory effect for external use.

Terms of sale from pharmacies

Can buywithout a doctor's prescription.

Price

How much is Triderm in pharmacies? The average price is at the level of750 rubles.

Composition and form of release

The drug Triderm is available in dosage forms for external topical application of ointment and cream. They have a homogeneous character, a viscous consistency (the ointment is more viscous than the cream), white.

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In 1 gram of Triderm ointment is 10 mg of clotrimazole, 1 mg of gentamicin, 0.5 mg of betamethasone. Additional components: liquid paraffin, soft paraffin.
The composition of 1 gram of Triderm cream also includes 10 mg of clotrimazole, 1 mg of gentamicin, 0.5 mg of betamethasone. Additional components: propylene glycol, petroleum jelly, liquid paraffin, cetostearyl alcohol, benzyl alcohol, macrogol macostatate, phosphoric acid, sodium dihydrogenphosphate dihydrate, water, phosphoric acid.

Ointment and cream are in tubes in the amount of 15 or 30 g. Cardboard pack contains 1 tube with ointment or cream, as well as instructions for the use of the drug.

What is better - cream or ointment?

Conditionally it can be said that the ointment is better to use for more severe and extensive skin lesions, and the cream is suitable for the treatment of mild degrees of dermatitis. In addition, the cream absorbs into the skin faster, so if necessary, apply the drug under the clothes, it is better to choose this dosage form, but not the ointment. Also, it is preferable to use an ointment cream when treating wet areas of the skin. Advantages of the cream on the wet areas before the ointment is that it is quickly absorbed and well-dried.

People who suffer from allergies or have sensitive skin can stop choosing Tridentum because they contain only paraffin and petroleum jelly in addition to the active ingredients. In cream, as auxiliary substances, contains alcohols and other synthetic compounds that can cause an allergic reaction or sensitize the human body.

pharmachologic effect

Polycomponent for external use. Combines antipruritic, anti-inflammatory, antiallergic and antiexudative effect of betamethasone with antifungal action of clotrimazole and antibacterial activity of gentamicin.

The resulting effect of the use of ointment (as well as cream) is made up of the properties of its ingredients:

Betamethasone is a synthetic hormone. He copes with inflammation, allergy and itching.
Clotrimazole is known to be an antifungal agent. It destroys fungal membranes, preventing their synthesis. Fungi, against which the substance is particularly effective, is Candida, Microsporum, Trichophyton.
Gentamicin belongs to antibiotics such as aminoglycosides. It easily passes through the cell membrane and inhibits protein synthesis (stopping this development of bacteria). The substance has a wide range of action. It destroys staphylococci, streptococci, intestinal and pseudomonas aeruginosa, Proteus, aerobacteria, Klebsiella.

Indications for use

What helps? The triderm is used to treat dermatoses complicated by infections caused by pathogens that are susceptible to its active components, and if they are suspected of having such infections. In particular, the drug is prescribed in the following cases:

eczema;
simple and allergic dermatitis;
atopic dermatitis (incl. diffuse neurodermatitis);
simple chronic lichen (limited neurodermatitis);
dermatomycosis (multicolored lichen, candidiasis, dermatophytosis), especially when localized in large folds of the skin and inguinal region.

Contraindications

As contraindications to the use of ointment / cream are diseases:

herpes simplex,
open wound,
cutaneous tuberculosis,
chickenpox,
skin reactions after the vaccine,
cutaneous symptoms of syphilis,
the age of children not older than two years,
hypersensitivity to the constituents of the drug.

The medicine requires caution (you need to consult a doctor):

in the first trimester of pregnancy,
with long-term treatment,
on a large area of the skin,
with the destruction of the integrity of the skin,
in the case of occlusive dressings.

Intended use for pregnancy and lactation

The drug during pregnancy and lactation can be used in limited doses under the constant supervision of a specialist.

The drug is applied a small layer on a limited area of damage. The maximum duration of therapy is 5 days. If the therapeutic effect is not traced after 2-3 days from the moment of application of the drug, the remedy is replaced by an analogue suitable for medical reasons.

The replacement of the remedy should be made by a specialist familiar with the history of the woman's illness.

Assignment to children

For children, the drug is prescribed only on strict indications and under medical supervision. systemic side effects, associated with the use of local corticosteroids, they can develop more often than in adult patients.

These side effects include: suppression of the hypothalamic-pituitary-adrenal system; Cushing's syndrome; growth retardation; slowing of the increase weight; increased intracranial pressure, manifested by bulging fontanelles, headache, bilateral edema of the optic disc.

Dosage and route of administration

As indicated in the instructions for use Triderm is intended for external use.

The triderm should be applied a thin layer on the entire affected surface of the skin and surrounding tissue 2 times / day - in the morning and at night. To ensure the effectiveness of treatment, the drug should be used regularly. The duration of therapy depends on the size and location of the lesion, as well as on the patient's response.

If clinical improvement does not occur after 3-4 weeks of treatment, this may serve as a reason for specifying the diagnosis.

Side effects

The consequences of the inclusion of an antibiotic in an external remedy sometimes appears as a skin rash or itching. Treatment in this case is not interrupted. After the Clotrimazole component, redness of the skin at the site of application can be observed in individual patients, epidermis, increased hydration, blistering, slight tingling, itching, puffiness, irritation and urticaria.

General local reactions to the drug are rare: melanin deficiency, itching, redness, exudation, tingling and burning in the area of Triderma.
Local reactions to the betamethasone contained in Triderma can be the formation of acne, increased hair formation, a decrease in melanin contained in the epitheliocytes, a sensation burning, itching, dermatitis of an allergic nature, formed during contact with the drug, folliculitis, maceration, striped atrophodermia, secondary infection.

Overdose

Symptoms of overdose with Triderm can be functional disorders of the adrenal glands, which is associated with prolonged use of local GCS in a higher dosage. With the aggravation of the situation, the development of secondary adrenal insufficiency may occur until the appearance of hypercorticism.

Participation in an overdose of such constituent components of the drug as clotrimazole and gentamicin does not show any symptoms. However, when gentamicin is taken for a long time in an overestimated dosage, growth of the flora may be insensitive.

As therapeutic measures should be carried out symptomatic therapy. With acute symptoms of hypercorticism, which, as a rule, differ in their reversibility, it is necessary to correct electrolyte imbalance. It will be necessary to cancel SCS if chronic toxicity is detected.

special instructions

Before you start using the drug, read the special instructions:

Triderm (ointment and cream) is not intended for use in ophthalmology.
With prolonged use of the drug, it is recommended to cancel it gradually.
Any side effects that occur with systemic GCS, including oppression of the adrenal cortex, may also occur with topical application of GCS, especially in children.
Prolonged local administration of antibiotics can sometimes lead to the growth of resistant microflora. In this case, as well as with the development of irritation, sensitization or superinfection in the background of treatment with Triderm, treatment should be stopped and appropriate therapy prescribed. There were cross-allergic reactions with aminoglycoside antibiotics.
Systemic absorption of GCS or gentamicin for topical application will be higher if treatment is performed on large areas of the skin or with the use of occlusive dressings, especially with prolonged treatment or in violation of the integrity of the skin. It is necessary to avoid applying gentamicin to open wounds and to damaged skin. Otherwise, there may be side effects, characteristic of gentamicin in its systemic application. Appropriate precautions should be taken in such cases, especially when treating children.

Interaction with other drugs

No interaction of the drug Triderm with other drugs has been reported.

Reviews

We offer to read reviews of people who used Triderm:

Sasha. At me atapichesky a dermatitis 23 years, Triderm perfectly approaches or suits in emergency situations when strong exacerbation. Quickly cleans allergy from the skin, BUT!!! guys, it is not recommended to use it on a regular basis. Allergic people need to have it in the nest on the emergency situation. And so diet, pills and more sparing analogues.
Vadim. The big plus of "Triderma", in comparison with other similar preparations - complex action. With it, you do not need to use antibiotics, either with the same "Advantan" or simple "Acriderm", with which we constantly take eczema from either Metrogil, Dalacin, or Erythromycin ointment. But the downside is that for this complex you have to pay quite a lot. It happens, it is cheaper to take several medicines than one tube of "Triderma".
Tatyana. Not so long ago on the temporal area of the face there was an incomprehensible speck, something like a lichen. He was at the doctor's, and after the tests he was assigned "Triderm". The medicine helped quickly, after a week already the speck passed. I liked the drug. My sister also had a similar case after six months, so she, without hesitation, took advantage of the "Triderm", and everything disappeared. He approaches many fungi.

The main drawback of the drug is the risk of serious side effects, which requires special care when applying ointment / cream, especially for children.

Analogues

Structural analogs for the active substance:

Acriderm GK;
Canison Plus.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

The shelf life of the ointment and cream of Triderm is 3 years. The preparation should be stored in the original factory packaging, dark, dry, inaccessible to children at an air temperature of +2 to +30 ° C.