How to take Libexin from a cough: the instruction to the drug

Libexin is an antitussive drug blocking the peripheral links of the cough reflex through a local anesthetic and the bronchodilating action of the active substance, as well as a slight decrease in the activity of the respiratory center.

A distinctive feature of the drug Libexin is: the absence of direct effects on the central nervous system, and also does not cause drug dependence and addiction, and its antitussive effect is approximately the antitussive activity of codeine.

Clinical and pharmacological group

Antitussive drug.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Libexin cost? The average price in pharmacies is at the level of450 rubles.

Form of issue and composition

Medicinal form - tablets: flat, round, white, on both sides - chamfer, on one of the sides - risk (allowing to divide the tablet into 4 parts), on the other - engraving "LIBEXIN" (20 pcs. in blisters, 1 blister in a pack of cardboard).

1 tablet contains:

active substance: iroxediazine hydrochloride - 100 mg;

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auxiliary substances: glycerol (E422), magnesium stearate (E470), talc (E553), polyvidone (E1201), corn starch, lactose monohydrate.

Pharmacological effect

The drug contains in its composition the active substance prenoxadiazine hydrochloride. The action of the drug is based on the suppression of the sensitivity of peripheral respiratory tract receptors. Also, the drug reduces the susceptibility of cough nerve fibers to irritation associated with inflammatory processes and mucosal edema with inflammatory diseases localized in the upper and lower respiratory tract.

The pronounced spasmolytic and bronchodilating effects contribute to the active widening and relaxation of the trachea and bronchi, which leads to the smooth passage of sputum. Libexin does not have a direct effect on the central nervous system, it does not cause addiction and drug dependence, and the antitussive effect of the drug is almost equal to that of codeine.

Indications for use

As indicated in the instructions to Liebesin, this medication should be taken with:

Pleuropneumonia;
Infarction of the lung;
Dry and exudative pleurisy;
Night cough for patients with heart failure;
Preparation for bronchographic or bronchoscopic examination;
Unproductive cough of various origin, in particular due to emphysema, pneumonia, acute or chronic bronchitis, influenza, upper respiratory catarrh, bronchial asthma.

Contraindications

Absolute contraindications:

Period after inhalation anesthesia;
Hypersensitivity to the drug;
Diseases accompanied by abundant bronchial secretion;
Malabsorption of glucose-galactose, deficiency of lactase, galactose intolerance.

Libexin should be used with extreme caution in the treatment of children.

Use in pregnancy and lactation

The limited data available do not indicate the presence of fetal (neonatal) toxicity in prenoxediazine and the ability to cause malformations. To date, there are no other relevant epidemiological data. The drug should be used with the usual precautions.

There is no clinical evidence as to whether the drug is excreted into breast milk, so during the period of feeding it can be used by a chest after a careful weighing of the relationship of benefit to risk, on the recommendation of a doctor.

Dosage and route of administration

The instructions for use indicate: Tablets Libexin is swallowed without chewing (to avoid anesthetizing the oral mucosa).

The average dose for adults is 100 mg 3-4 times / day (1 tab. 3-4 times / day). In more complicated cases, the dose can be increased to 200 mg 3-4 times / day or up to 300 mg 3 times / day (2 tab. 3-4 times / day or 3 tablets 3 times / day).
The average dose for children, depending on the age and body weight of 25-50 mg three or four times a day (1/4 - 1/2 table. 3-4 times / day).
The maximum single dose for children is 50 mg (1/2 tab.), For adults - 300 mg (3 tablets). The maximum daily dose for children is 200 mg (2 tablets), for adults - 900 mg (9 tablets).
When preparing for bronchoscopy, the dose of 0.9-3.8 mg / kg of body weight is combined with 0.5-1 mg of atropine for 1 hour before the procedure.

Instructions for Libexin Muco

Libexin Muko is an expectorant and phlegm-diluting drug, which is available in the form of 2 varieties of syrup (for children and adults). The active substance of this drug is carbocysteine.

Average dosage:

Children 2-5 years - 5 ml of syrup (ie, 1 measuring spoon) 2 times a day;
Children older than 5 years - the same dose 3 times a day.

The duration of treatment by Libexin Muko is determined by a doctor, but usually the course does not exceed 8 days.

Since the syrup is characterized by a sweet taste and contains 3.5 g of sucrose in 1 measuring spoon, it is best to avoid assigning it children suffering from diabetes; and in the case of the appointment, it is more often to control the sugar level in the child's blood.

Side effects

During therapy, the following side effects may develop:

Nervous system: when using Libexin in high doses - fatigue, mild sedative effect.
Allergic reactions: rarely - skin rash, angioedema.
Gastrointestinal tract: rarely - dryness in the throat or mouth, anesthesia (loss of sensitivity and temporary numbness) mucous membrane of the oral cavity; less than 10% of cases - a tendency to constipation, pain in the stomach, nausea.

As a rule, fatigue and sedation are manifested when taking the drug in doses exceeding the recommended ones. These symptoms stop spontaneously within a few hours after drug withdrawal.

Overdose

Overdose of any drug occurs in cases of taking the drug, in dosages exceeding the mediotherapy prescribed maximum daily allowance or single dose. And also with uncontrolled and long-term administration of the drug, which contributes to the accumulation of an active active substance in the body, which can also occur if there is a violation of its excretion from the body, associated with the pathology of the kidneys or liver.

Symptoms of an overdose of this drug are nausea, dizziness, weakness, increased fatigue or skin allergic reaction.

With extreme caution should take this drug in childhood. It is taken only with the appointment of a doctor, with a clear dose control and frequency of admission. Very often in children, the reaction of the body to taking the medication, especially if it is prescribed for the first time, is unpredictable, so even a minimal increase in a single or daily dose of the drug means can cause the development of allergic reactions of an immediate type (anaphylactic shock, Quincke's edema), and when they occur, you need to seek medical help.

special instructions

Before starting taking Libexin tablets, you should carefully read the summary of the drug. There are several specific indications regarding their application, which include:

In childhood, the drug should be used with caution.
Reception of a preparation can cause development of the expressed dyspepsia at persons with infringement of digestion and absorption of lactose.

When the drug is administered in high dosages, it has a sedative effect and reduces the speed of psychomotor reactions and the ability to concentrate.

Drug Interactions

It is not recommended to combine the drug with mucolytic and expectorant, it can make it difficult to isolate sputum liquefied by the latter. There are no preclinical or clinical data on the interaction with other drugs.

Reviews

We picked up some reviews of people taking the drug Libexin:

Ruslana. With a dry cough, libexine really helps, sputum goes off quickly enough, and when coughing it is a great relief. Dry cough just exhausts, that even at night you can not fall asleep from it! With the use of this drug, desires for coughing are reduced, only in taking medication, of course, need consistency and regularity, as in other cases!
Nadia. With a dry irritating cough that appeared after a sore throat, it helps. The instructions clearly state that with a damp cough and in combination with expectorant and thinning liquor, do not use.
Sergei. I think people with chronic bronchitis are familiar when inhaling cold air immediately starts coughing. A terrible feeling. The same nonsense I have. This tool is not a panacea, but it helps this whole process to flow milder. The sputum coughs up faster, the cough is more intense but lasts less. What can I say, just try. In principle, the price does not bite, you can use a lot and for a long time. It is unique, that the liver strongly overloads (in the tablet form 2 \ 3 preparations filters a liver). If you use during the height of the disease, the liver will not suffer, and you will recover faster.

Analogues

If, for one reason or another, Libexin does not work, this remedy can be replaced with another antitussive drug, for example:

With the drug Kodelak Neo. Such a drug based on butramate is released in drops (allowed from 2 months of age), syrup (prescribed at the age of 3 years and older) and tablets (do not give to children). The medication affects the cough center, which leads to the suppression of the cough reflex, so it is especially in demand with a painful dry cough.
Syrup Paxelidine. Such a preparation based on oxeladine has the ability to affect the cough center, but it does not inhibit breathing, but on the contrary, stimulates it. In childhood, he is appointed from 2.5 years old with a child's body weight above 15 kg.
Syrup Broncholitin. The composition of this drug combined glaucin and ephedrine. Such substances affect the cough reflex, and also eliminate mucosal edema, stimulate breathing and dilate the bronchi. In childhood, the drug is used from 3 years. Analogues of this drug with the same composition are the syrups Bronchoton and Bronchocin.
Syrup of Sinekod. This medicine with vanilla flavor contains butamate and is also available in drops allowed from two months of age. Sinecode in syrup is used for dry cough from 3 years.

Before using analogues, consult your doctor.