Sanorin belongs to the pharmacological group of vasoconstrictor drugs, widely used in otolaryngological practice. It is released in the form of nasal drops. Another form of release is a nasal spray.
Intranasal administration causes a pronounced, rapid and prolonged vasoconstrictive effect on the vessels of the paranasal sinuses and mucous membranes of the nose, as well as the nasopharynx. It is expressed in the reduction of swelling and hyperemia, which improves the patency of the nasal passages and there is relief of nasal breathing.
The patency of the Eustachian tubes also improves. The therapeutic effect is usually observed after 5 minutes after the application of Sanorin and lasts approximately 4-6 hours.
Clinical and pharmacological group
Vasoconstrictive drug for topical application in ENT practice.
Terms of sale from pharmacies
You can buy without a doctor's prescription.
Price
How much does Sanorin cost in pharmacies? The average price is at the level of190 rubles.
.Composition and form of release
Sanorin is available in the following forms:
- drops nasal, 5% and,%: in the form of a transparent colorless liquid (10 ml in bottles-droppers of dark glass, in a cardboard bundle one bottle);
- nasal spray,%: as a colorless transparent liquid, odorless and without visible particles (10 ml each in plastic bottles with a mechanical dispensing applicator, in a cardboard bundle one bottle).
Composition 1 ml of drops:
- active ingredient: naphazoline nitrate mg or 1 mg;
- auxiliary components: methyl parahydroxybenzoate, boric acid, water, ethylenediamine.
Composition 1 ml of spray:
- active ingredient: naphazoline nitrate - 1 mg;
- auxiliary components: methyl parahydroxybenzoate, boric acid, water, ethylenediamine.
Varieties of Sanorin
On the pharmaceutical market there are several types of drops Sanorin:
- With eucalyptus. Sanorin with eucalyptus oil is one of the most popular types of this drug. It has pronounced antimicrobial and anti-inflammatory properties. Sanorin with eucalyptus oil has the fastest therapeutic effect, which is due to the parallel action of naphazoline and eucalyptus oil.
- Sanorin Anaerhegine - includes in its composition such a component as mesylate antazolin, which has an antihistamine and soothing effect. Antazolin prevents the development of reactions of allergic origin, and also promotes their maximum rapid elimination. This kind of remedy is especially effective in rhinitis allergic type and in the case of diagnosed allergic conjunctivitis.
- Sanolin Xylo is a softer and safer variant of drops. Unlike other types of this drug, the main active substance Sanorina Xylo is xylometazoline, which exerts an exclusively local effect, practically without penetration into the region systemic blood flow. It is this medication that is recommended for use in children, as well as in pregnancy, but only for the prescription of the attending physician and in minimal dosages!
pharmachologic effect
The main active ingredient of Sanorin is naphazoline, which belongs to alpha2-adrenomimetics. This substance has a local vasoconstrictive effect on the capillaries of the mucous layer of the nose, eliminating the symptoms of acute inflammation-edema, exudation and hyperemia.
In the case of acute rhinitis, the use of Sanorin promotes the restoration of nasal breathing, and in otitis and other diseases, the nasopharynx restores the patency of the Eustachian tube.
Eucalyptus oil, part of the emulsion, enhances anti-inflammatory effect. Very often the drug is used as a decongestant during the treatment of bacterial conjunctivitis. For longer than 7 days, sanorin is contraindicated, as it causes addiction and unwanted reactions.
Indications for use
Sanorin is recommended for:
- acute rhinitis of various origin;
- otitis media, as an additional agent, which can reduce the swelling of mucous nasopharynx;
- sinusitis;
- eustachite;
- laryngitis;
- the need to reduce the swelling of the mucous membranes of the nose, paranasal sinus and nasopharynx for medical and diagnostic procedures, as well as stop bleeding from the nose.
Contraindications
Absolute:
- tachycardia;
- arterial hypertension;
- chronic rhinitis;
- diabetes;
- thyrotoxicosis;
- severe atherosclerosis;
- angle-closure glaucoma;
- Children under 2 years old - for drops of nasal, 5%, up to 15 years - for emulsion, drops and spray,%;
- simultaneous use of monoamine oxidase inhibitors and 14 days after their cancellation;
- hypersensitivity to the components of the drug.
Carefully:
- ischemic heart disease (angina);
- pheochromocytoma;
- hyperplasia of the prostate;
- pregnancy and lactation.
Intended use for pregnancy and lactation
At the moment, no special studies have been conducted on the effects of sanorin on the course of pregnancy. There is no evidence that refutes or confirms the penetration of active substances of sanorin through the hematoplacental barrier (prevents the entry of harmful substances from the mother's blood into the fetal blood).
Based on these data, it can be said that sanorin does not have a direct effect on the child. But acting on the mother's body, it can disrupt her blood circulation and, as a result, disrupt the delivery of oxygen and nutrients to the baby. Thus, sanorin can indirectly through the mother have a negative impact on the child.
The use of sanorin is not strictly contraindicated in pregnancy, but it is extremely undesirable due to the poor knowledge of its effect on the intrauterine development of the child. Apply it only if you are prescribed by a doctor or in case of severe nosebleeds, which can not be stopped. In case of bleeding, a single dose should be dripped into both nasal passages. If bleeding does not stop within 10 to 15 minutes, you need to call an ambulance or see a doctor. With repeated nasal bleeding it is necessary to consult a doctor without fail.
Dosage and route of administration
As indicated in the instructions for use in acute rhinitis, sinusitis, eustachyte, laryngitis, to facilitate the conduct of rhinoscopy for adults, children and adolescents over 15 years - 1-3 drops of nasal drops 0.1% or 1-3 doses of nasal spray in each nasal passage 3-4 times / day; drops nasal 0.1% in the form of an emulsion appoint 1-3 drops in each nasal passage 2-3 times / day.
- Children older than 2 years - 1-2 drops of nasal drops 0.05% in each nasal passage 2-3 times / day with an interval of not less than 4 hours.
- Apply for a short time: for adults - no more than 1 week, for children - not more than 3 days. If nasal breathing is facilitated, Sanorin can be used sooner. Repeated use of the drug is possible in a few days.
- With nosebleeds, you can put a cotton swab moistened with 0.05% Sanorin solution in the nasal passage.
- As an additional remedy for the treatment of conjunctivitis of bacterial origin, a drop of nasal 0.05% drop by 1-2 drops 3-4 times / day is instilled in the conjunctival bag.
- Nasal drops in the form of an emulsion must be shaken before use. Open the vial with the drug should be used within 4 weeks.
When using the spray for the first time, it is recommended to press the metering device several times until a compact aerosol cloud appears. Before direct use, remove the protective cap, keep the vial with the preparation in a vertical position, the end part of the dosing device is inserted into the nasal passage, then quickly and sharply press on applicator. Immediately after injection, it is recommended to breathe lightly. After applying the preparation, cover the applicator with a protective cap.
Side effect
Against the background of the use of the drug, it is possible to develop systemic side effects, among which:
- nausea;
- tachycardia;
- increased pressure;
- headache;
- irritability;
- rash.
Local reactions can also develop:
- reactive hyperemia;
- swelling of the nasal mucosa;
- irritation and swelling of the mucosa (if the drug is used for more than 7 days).
Overdose
In case of an overdose, nasal congestion is noted. Prolonged use of the drug leads to addiction, as a constant obstruction prevents normal nasal breathing.
In young children, Sanorin overdose manifests itself by the following symptoms: general weakness, increased sweating, drowsiness, slowing of heart rate and lowering of body temperature. In severe cases, an overdose of the drug can cause someone.
special instructions
Naphazoline nitrate may have a resorptive effect.
With prolonged use of Sanorin, the severity of its vasoconstrictor effect gradually decreases, the need for long-term treatment is recommended to take a break for several days: adults after 5-7 days of treatment, children - in 3 days.
Care should be taken in general anesthesia with the use of anesthetics, which increase sensitivity of the myocardium to sympathomimetics (for example, halothane), especially in patients with bronchial asthma.
Information on the penetration of naphazoline through the placental barrier and into breast milk is not, therefore, during pregnancy and breast-feeding a drug can be prescribed only after a thorough evaluation of the benefits and possible risks.
Interaction with other drugs
Simultaneous administration with MAO inhibitors and a period of up to 14 days after the end of their use increases the risk development of severe arterial hypertension (release of deposited catecholamines under the action of naphazoline). Slows the absorption of local anesthetics.
Reviews
We offer you to read reviews of people who used Sanorin:
- Milan. My daughter helps very well from a cold and stuffy nose. She then colds, then the teeth are cut, that's where the soplets appear. To drip it is necessary often, the effect is felt next day. And the shape is comfortable. Earlier, the two of us were holding a child to get into the nose with a pipette, but now it's ready! The girl sleeps quietly, eats well, without whims.
- Vladislav. I spent a sleepless night with sanorin. The action is short, you do not notice how you wake up with a stuffy nose, then again a dose in the nose, and then insomnia, again stuffy nose, tachycardia.
- Alla. During pregnancy, I constantly pawns my nose. This is not a cold, but such a bad condition. And the higher the air temperature, the more lays. I used different drugs, because one is addictive. One day she took this Sanorin. Of course, the spray dispenser is convenient, but tiny and expensive. The instructions say, sprinkle 7-8 r / d for 2 weeks. So this bubble is not enough for so much, you need to buy more. But it would not matter if the medicine helped. I splashed several times a night, but I could not fall asleep, my nose was constantly laid.
Analogues
Structural analogs for the active substance:
- Nafazolin Ferein;
- Naphthysine;
- Sanorin with eucalyptus oil.
Before buying an analogue, consult your doctor.
Shelf life and storage conditions
Such drops in the nose should be stored in a cool and dark place, inaccessible to children. Shelf life 4 years.
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