Ketanov tablets: instructions for use

Ketanov is a non-steroidal anti-inflammatory agent of pronounced analgesic, anti-inflammatory and moderate antipyretic effect, a pyrrolizine-carboxylic acid derivative.

The drug is used for pain syndromes of various etiologies. Methods of administration: orally and parenterally (intramuscular injection). Recommended for short use.

On this page you will find all information about the Ketanov: full instructions for use on this medicated medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Ketanov. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

NSAID, a pyrrolizine-carboxylic acid derivative.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does the Ketanov cost? The average price in pharmacies is at the level of70 rubles.

Is Ketanov forbidden?

In many countries of Europe Ketanov is banned for use because of registered in the 90s In the past century, more than 100 deaths were caused by severe complications caused by drug. Since that time, registration of the drug has been canceled in some countries, and it has ceased to be sold in principle.

In other countries, Ketanov is still used, but is sold only on prescription. Since 2012 and in Russia, Ketanov's prescription vacation has been introduced, but in practice many pharmacies sell it freely.

Form of issue and composition

One coated tablet contains:

• Active substance: ketorolac trometamol - 1, 0 mg.
• Excipients: corn starch - 4, 6 mg, microcrystalline cellulose - 12, 1 mg, silicon dioxide colloid 3 mg, magnesium stearate 0 mg.
• Film membrane: hypromellose 1 mg, macrogol - 400 8 mg, talc purified 6 mg, titanium dioxide 5 mg.

Round biconvex tablets covered with a sheath, white or almost white with an engraving "KVT" on one side.

Pharmacological effect

In the role of the active substance of the drug acts ketorolac, which has a pronounced analgesic, moderate antipyretic and anti-inflammatory effect.

Unlike narcotic analgesics, the use of Ketanov does not affect the psychomotor functions and the functioning of the heart muscle, does not depress the respiratory center and does not cause drug dependence.

By the strength of the analgesic effect, Ketanov significantly exceeds other NSAIDs and is equivalent to morphine.

Indications for use

As a rule, as the main indication for the use of Ketanov, the elimination of painful sensations of any location and nature is considered. In general, the following applications are considered:

• elimination of pain from injuries, fractures, bruises;
• Elimination of soreness after any surgical operations.

Shortly, Ketanov can anesthetize such conditions as:

1. Otitis;
2. Fibromyalgia (pain in the muscles);
3. Pain in osteoarthritis or osteoarthritis;
4. Pain in malignant tumors;
5. Ischialgia (pain along the sciatic nerve);
6. Radicular syndrome;
7. Pain after withdrawal of narcotic analgesics;
8. Tooth pain in any dental diseases (for example, pulpitis, caries, periodontitis, etc.);
9. Pain during dental procedures;
10. Bile or renal colic (in combination with antispasmodics);
11. Pain after delivery and episiotomy (perineal incision);
12. Osteochondrosis.

With sharp and sharp pain in the abdomen, it is not recommended to drink Ketanov, as this can hide states that need to be treated surgically immediately.

Ketanov from toothache

When there was a toothache, do not immediately take pills. Try first to thoroughly brush your teeth with a toothpaste, and then rinse your mouth every few minutes with Rotocan. Effective with a toothache Metrogildenta. If this does not help, and you can not go to the dentist at the moment, you can use the Ketanov drug.

The tablet can be drunk, and you can put it on a sick tooth - so you forget about the pain for 3-5 hours. When you resume it, take another 1 tablet, but no more. Do not abuse this medicine, because it is a powerful analgesic, similar in properties to opium. It also adversely affects the liver, and in combination with alcohol can lead to the rejection of this body.

Contraindications

Contraindications to the use of Ketanov are:

1. Treatment of chronic pain;
2. Simultaneous administration with other NSAIDs;
3. Pregnancy, childbirth, the period of breastfeeding;
4. Children and adolescents under 16 years of age, since safety and efficacy have not been established;
5. Renal and / or hepatic insufficiency (with a plasma creatinine level above 50 mg / ml);
6. Anesthesia before or during surgery (due to an increased risk of bleeding);
7. Peptic ulcers, erosive-ulcerative lesions of the gastrointestinal tract in the acute stage, hypocoagulation (including hemophilia);
8. Hemorrhagic diathesis, hemorrhagic stroke (suspected or confirmed), hematopoiesis, high risk of recurrence or development of bleeding (including after operations);
9. Hypersensitivity to ketorolac or other NSAIDs, angioedema, bronchospasm, "aspirin asthma dehydration and hypovolemia.

Ketanov is cautiously prescribed to persons over 65 years of age and patients with the following diseases:

1. Sepsis;
2. Active hepatitis;
3. Cholestasis;
4. Systemic lupus erythematosus;
5. Chronic heart failure;
6. Bronchial asthma;
7. Arterial hypertension;
8. Cholecystitis;
9. Impaired renal function (with plasma creatinine below 50 mg / ml);
10. Polyps of the nasopharynx and nasal mucosa.

Application in pregnancy and lactation

Ketanov in any form is contraindicated for use in pregnancy and lactation. To its use during pregnancy can be resorted only to the vital indications from the mother. If Ketanov is indicated for a nursing mother, then for the period of its application the woman should transfer the child to artificial mixtures.

During labor, Ketanov should also not be used for analgesia, since the drug lengthens the course of the genital act and weakens the contractile activity of the uterus, which can provoke serious complications, including bleeding.

Women who are forced to use Ketanov during pregnancy should not worry much, because in animal experiments there was no negative effect of the drug on the fetus. However, in females who received Ketanov, late birth and pregnancy delay were observed.

Instructions for use

The instructions for use indicate that Ketanov in the form of tablets are taken orally.

Single dose for a single dose is 10 mg (1 tablet). If necessary, the drug in the same dose can be taken up to 4 times a day (maximum - 40 mg per day).

Intramuscularly (deep) Ketanov in the form of a solution for injection should be injected into the minimally effective doses, which the doctor chooses individually depending on the intensity of pain and reaction on therapy. If necessary, simultaneous use with reduced doses of opioid analgesics is possible.

With a single intramuscular injection, single doses of Ketanov are:

• Patients under 65 years of age - 10-30 mg (determined by the severity of the pain syndrome);
• Patients over 65 years of age or patients with functional renal impairment - 10-15 mg.

With repeated intramuscular injection, the following is usually used:

• Patients under 65 years of age - 10-30 mg, then every 4-6 hours for 10-30 mg;
• Patients over 65 years of age or patients with functional renal impairment - every 4-6 hours for 10-15 mg.

The maximum daily doses for intramuscular injection are:

• Patients under 65 years of age - 90 mg;
• Patients over 65 years of age or patients with functional kidney disorders - 60 mg.

The same total daily doses should not be exceeded during the transition from parenteral administration of Ketanov to taking the drug inside (on the day of transition, admission of 30 mg of the drug inside).

The duration of application of Ketanov in any dosage form should not exceed 5 days.

Side effects

The use of Ketones can cause the following side effects:

1. Central nervous system: often - drowsiness, dizziness and headache; rarely - hyperactivity (anxiety, changes mood), hallucinations, psychosis, depression, aseptic meningitis (severe headache, fever, rigidity of the back and / or neck muscles, convulsions);
2. Urinary system: rarely - frequent urination, edemas of renal genesis, nephritis, increase or decrease of urine volume, hemolytic uremic syndrome (hemolytic anemia, purpura, thrombocytopenia, renal failure), back pain (including hematuria and / or azotemia), acute renal failure;
3. The digestive system: often (especially in people over the age of 65, in whose anamnesis there are indications of erosive and ulcerative lesions of the digestive tract) - diarrhea, gastralgia; less often - flatulence, a feeling of overflow of the stomach, vomiting, constipation, stomatitis; rarely - erosive-ulcerative lesions of the gastrointestinal tract (including with bleeding and / or perforation - burning or spasm in the epigastric region, abdominal pain, heartburn, nausea, vomiting like "coffee grounds melena, etc.), nausea, hepatitis, acute pancreatitis, cholestatic jaundice, hepatomegaly;
4. Cardiovascular system: less often - increased blood pressure; rarely - a syncope, pulmonary edema;
5. Sensory organs: rarely - ringing in the ears, hearing loss and visual impairment (including blurred vision);
6. Hemopoiesis: rarely - eosinophilia, anemia, leukopenia;
7. Respiratory system: rarely - rhinitis, dyspnea or bronchospasm, laryngeal edema, manifested by shortness of breath and difficulty breathing;
8. Hemostasis system: rarely - nasal or rectal bleeding, bleeding from a postoperative wound;
9. Allergic reactions: rarely anaphylaxis or anaphylactoid reactions (skin itching, rashes, hives, discoloration of the face, swelling of the eyelids, dyspnea, heaviness in the chest, tachypnea or dyspnea, shortness of breath, periorbital swelling, wheezing breath);
10. Skin: less often - purpura, skin rash (including maculopapuluses); rarely - hives, exfoliative dermatitis (fever, sometimes with chills, peeling, redness and / or denseness of the skin, soreness and / or swelling of palatine tonsils), Lyell's syndromes and Stevens-Johnson;
11. Other: often - swelling (feet, fingers, ankles, legs, face), weight gain; less frequent - increased sweating; rarely - fever, swelling of the tongue.

Overdose

Symptoms of overdose: nausea, vomiting, abdominal pain, the formation of peptic ulcers of the stomach, erosive gastritis, metabolic acidosis, impaired renal function.

Treatment: gastric lavage, the appointment of adsorbents and symptomatic therapy.

special instructions

In the postoperative period, Ketanov should be used with caution, while controlling the clotting ability of blood. This is due to a greater risk of bleeding in the postoperative period.

The drug is used with particular caution in patients with inhibition of liver function and impaired cardiac activity. Patients with erosive gastritis or peptic ulcer in the history of the treatment of drugs can be carried out only with the permission of a specialist after a preliminary examination.

Since during the use of the drug hypersensitive patients may complain of dizziness, headaches and drowsiness, then you should avoid driving the car and controlling complex mechanisms that require increased concentration attention.

Drug Interactions

With the simultaneous use of ketorolac with other NSAIDs, it is possible to develop additive side effects; with pentoxifylline, anticoagulants (including heparin in low doses) - possibly increased risk of bleeding; with ACE inhibitors - there may be an increased risk of kidney dysfunction; with probenecid - the concentration of ketorolac increases plasma and its half-life; with lithium preparations - it is possible to reduce renal clearance of lithium and increase its concentration in plasma; with furosemide - a decrease in its diuretic actions.

When ketorolac is used, the need for opioid analgesics for analgesia is reduced.

Compatibility with alcohol

This drug with alcohol is incompatible, as the risk of gastrointestinal side effects increases in the form of gastralgia, abdominal pain and bleeding from the digestive tract. Alcohol strengthens the anesthetic effect, so you can skip the moment when you need to urgently consult a doctor. In addition, it increases the inhibitory effect on the central nervous system, causing drowsiness, inhibition.

Reviews

We picked up some responses from people about the Ketanov drug:

1. Lera. A good drug, saves the whole family from back pain, teeth and head. Acts immediately, and for a long time. We can safely forget about the pain for the whole day. Completely satisfied with the action of the drug and its affordable price. It's bad that in pharmacies without a doctor's prescription you can not get it, and doctors by that time do not hurry to write prescriptions, unfortunately, you have to come back and defend the live queue anew. In general, there are certainly no complaints about the drug and its effect, it saves at the right time. And, importantly, it has analogues lower in cost, which can be purchased without a doctor's prescription, having a lower cost and no less effective.
2. Masha. Six months ago I put braces. For the first five days my teeth ached unbearably. Many people recommended drinking Nimesil, but he does not help me, but the Ketanov simply saved me. Always in a cosmetic bag I wear a plate of "Ketanov as I can not bear a toothache, but it quickly acts and for a long time there is enough effect from a tablet. And there was a case that the head was very sick and apart from "Ketanov" nothing was with itself. So I drank it, and helped.
3. Ksenia. At me at monthly very morbid the first day. Tried a lot of different painkillers including noshpu and tempalgin. I did not give, ol did not go. I read on the Internet about ketano, I do not know the cure for pain now! If I know that today's monthly just drink a pill and forget about the pain at all)))) Yesterday while at home let me think do not drink, se taki also sat down on the Ketas. Zr, ace I will die !!)))) At night, I could not stand the pain, it already reduces everything... I got up and drank, and how in the hour, through the hour, everything is in the norm, ospodi thank you who esgo is created, I'm not the one who thinks so !!!)) )

Analogues

If necessary, Ketanov can be substituted for other structural analogs containing the same active component or other drugs with similar therapeutic effect. Among them:

• Adolor tablets;
• Dolak solution and tablets;
• Dolomin solution;
• Ketalgin solution and tablets;
• Ketorol solution, tablets and gel;
• Ketolac tablets;
• Ketorolac solution and tablets;
• Ketopril solution and tablets;
• Ketokam tablets.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Keep the tablets away from small children at room temperature. The shelf life of the tablets is indicated on the package, at the end of which the drug can not be taken orally.

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