Instructions for use: nimesil in powder form

Nimesil - instructions and testimonials on the application, powder dilution, medication and prices

To remove the inflammatory process, without taking medications is difficult to do.

The choice is complex, therefore it is better to coordinate it with the attending physician beforehand.

Abstract Nimesil makes it clear that this is an effective remedy for pain and cold, which belongs to the group of non-steroidal anti-inflammatory drugs.

Nimesil - instructions for use

The medical preparation is available in the form of a powder of light yellow color, which has a pleasant orange taste. Small granules dissolve in water, and the resulting suspension can bring down the temperature, remove severe attacks of pain, weaken the inflammatory process.

This therapeutic effect is achieved by the composition of the chemical formula, where the active ingredient is nimesulide. It is a synthetic substance with a stable antipyretic, anti-inflammatory and restorative effect.

The drug in single-dose bags is sold in each pharmacy.

If the doctor has prescribed a drugNimesil - instructions for usedescribes the pharmacological properties of the drug, for example, nimesulide its maximum concentration in blood plasma reaches 2-3 hours after the first administration, dissociates in the liver and is excreted by inactive metabolites kidneys. This suggests that when these organs are dysfunctional, it is important to individually adjust the daily doses, or take an analog with a softer effect.

Application of Nimesilagainst signs of pain and cold is a good decision, as this drug is imperceptibly adapts in the body, can quickly anesthetize, has a small amount of contraindications and side effects phenomena.

Among other medical indications, it is necessary to distinguish such diagnoses and organism states:

• elimination of pain on the background of progressive osteoarthritis;
• pain syndrome of unknown etiology;
• algodismenorea;
• toothache;
• feverish conditions;
• rheumatic and infectious lesions;
• signs of a cold.

How to grow Nimesil

More often the medication is prescribed in adulthood, children under 12 years old are not allowed to take home therapy. Beforehow to breed Nimesil, it is required to study the instruction in detail, to determine the features of the clinical picture.

The average dosage for a day is 2 packets of powder, taken in the morning and in the evening. One portion of the medicine should be diluted in 100 ml of boiling water, mixed, cooled, taken orally.

After cooking, a single portion of Nimesil can not be left in the refrigerator, the instruction informs you about the use of a fresh dose each time.

How to drink Nimesil

The use of this therapeutic powder is appropriate at home. Beforehow to apply Nimesil, it is important to study the instruction. It says that it is important for children of 12 years to adjust a single dose.

The same is done for patients with renal and hepatic insufficiency, at an advanced age. Single dose can be mixed in the food, be sure to wash down with water, supplement the recipes of alternative therapy at the insistence of the doctor.

How to drink Nimesil properly, as stated in the instructions.

Nimesil - contraindications

The instructions set out the restrictions under which it is prohibited to use this drug.

Before admissionNimesil contraindicationsit is required to study, drug interaction and compatibility with tablets of other pharmacological groups.

Not everyone is allowed such treatment, self-medication can only harm. It is not recommended to use tablets or Nimesil powder in the following clinical pictures:

• periods of pregnancy and lactation;
• pathology of the mucosa of the gastrointestinal tract;
• tendency to bleeding;
• seizures of bronchial asthma;
• propensity to thrombosis;
• systematic abuse of alcohol;
• children's age (not to give a child under 12 years of age);
• individual intolerance to Nimesil.

Price for Nimesil

The cost of the drug is always available. To save money, you can order and buy in the online store Nimesil. The reviews say that the catalogs include not only prices, but also instructions for medicines.

On average, the price for 10 bags is 700 rubles, Nimesulide tablets are cheaper - up to 100 rubles. Reviews about the second drug are mediocre, but its effect is also able to eliminate signs of pain and SARS.

Before inquiring how much Nimesil costs, it is important to consult with a specialist, listen to his feedback.

: how to take Nimesil

Reviews

A source: http://sovets.net/8063-nimesil-instrukciya.html

Nimesil - official instructions for use, analogues

Symptomatic treatment of osteoarthritis, rheumatoid arthritis, Bechterew's disease and other inflammatory and degenerative diseases accompanied by pain syndrome. Anomalies, articles

INSTRUCTIONS
on medical use of the drug

Trade name of the drug:Nimesil®

International Nonproprietary Name (MIN):nimesulide

Dosage form: granules for the preparation of a suspension for oral administration.

Package 1 contains:
Active substance: nimesulide 100 mg;
Excipients: ketomacrogol 1000, sucrose, maltodextrin, citric acid anhydrous, orange flavor.

Description:light yellow granular powder with an orange smell.

nonsteroidal anti-inflammatory drugs (NSAIDs).

ATX code:M01AX17

Pharmacological properties

Pharmacodynamics Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) from the class of sulfonamides.

Has anti-inflammatory, analgesic and antipyretic effect.

Nimesulide acts as an inhibitor of the cyclooxygenase enzyme responsible for the synthesis of prostaglandins and inhibits mainly cyclooxygenase 2.

.

Pharmacokinetics After ingestion, the drug is well absorbed from the gastrointestinal tract, reaching a maximum concentration in the blood plasma after 2-3 hours; connection with plasma proteins - 9,%; the half-life is -6 hours.

.

Easily penetrates through the histohematological barriers. Metabolised in the liver with the cytochrome P450 isoenzyme (CYP) 2C9. The main metabolite is the pharmacologically active parahydroxy derivative of nimesulide - hydroxynimidesulide.

Hydroxynimesulide is excreted in the metabolized form with bile (found only in the form of glucuronate - about 29%). Nimesulide is excreted from the body, mostly by the kidneys (about 50% of the dose taken).

The pharmacokinetic profile of nimesulide in elderly patients does not change with the administration of single and multiple / repeated doses.

Indications for use

• Treatment of acute pain (pain in the back, lower back, pain in the musculoskeletal system, including trauma, sprains and joints, tendenitis, bursitis, toothache);
• Symptomatic treatment of osteoarthritis with pain syndrome;
• Algodismenorea.

The drug is intended for symptomatic therapy, reducing pain and inflammation at the time of use.

Contraindications

• Hypersensitivity to nimesulide or to one of the components of the drug.
• Hyperergic reactions (in the anamnesis) for example, bronchospasm, rhinitis, urticaria, associated with admission Acetylsalicylic acid or other non-steroidal anti-inflammatory drugs, including nimesulide. Hepatotoxic reactions to nimesulide (in the anamnesis).
• Concomitant (simultaneous) administration of drugs with potential hepatotoxicity, for example, paracetamol or other analgesic or non-steroidal anti-inflammatory drugs.
• Inflammatory bowel disease (Crohn's disease, ulcerative colitis) in the phase of exacerbation. The period after aortocoronary bypass surgery.
• Feverish syndrome for colds and acute respiratory-viral infections.
• Complete or incomplete combination of bronchial asthma, recurrent nasal polyposis or paranasal sinuses with intolerance to acetylsalicylic acid and other NSAIDs (including in the anamnesis);
• Peptic ulcer of the stomach or duodenum in the phase of exacerbation, the presence in the anamnesis of an ulcer, perforation or bleeding in the gastrointestinal tract.
• Presence in an anamnesis of cerebrovascular bleeding or other bleeding, as well as diseases accompanied by bleeding.
• Severe blood clotting disorders.
• Severe heart failure.
• Severe renal insufficiency (creatinine clearance 10), often (

A source: https://medi.ru/instrukciya/nimesil_5599/

Nimesil - instructions for use in tablets or powder, analogues and price

This anti-inflammatory non-steroidal agent, which has an obvious antipyretic, analgesic effect. The main active substance is nimesulide.

According to consumers, this drug has a rapid therapeutic effect, which lasts for 6 hours.

Below, we will consider how to dilute and take Nimesil.

Nimesil - indications for use

The doctor can prescribe painkillers Nimesil if it is necessary to conduct the patient treatment of diseases of an infectious character (ARVI), we need therapy of degenerative inflammatory pathologies of the musculoskeletal system, to which includes:

• osteoarthritis;
• arthritis;
• radiculitis;
• bursitis;
• osteochondrosis.

The medicine will help to get rid of the heat of different genesis, urological, gynecological, vascular diseases.

The use of Nimesil in powder or tablets is also justified for the removal of dental, headache, during menstruation or after surgery or trauma.

Admission should follow the instructions to avoid side effects and overdose.

The drug is produced in two pharmacological forms - a powder for dilution in water or tablets.

A person should know in which water to dilute Nimesil and the correct dosage in order to achieve maximum effect.

Depending on the age, different amounts of the drug will be prescribed. Instructions for use Nimesil in powder:

1. Adults need 2 times a day to drink 1 packet of medication. In 100 ml of room temperature water, stir 1 bag. Drink the suspension immediately, because the drug can not be stored.
2. For children and adolescents, dosage does not require adjustment, so the method of application is the same. The maximum duration of admission is 15 days.
3. Children under the age of 12 can not be given this medicine.
4. For the elderly, the daily norm should be adjusted by the attending physician. It is advisable to conduct therapy with a minimal dose of medication in a short course.

Pills

This is the second form of the drug, which is available for purchase at the pharmacy.

Like any non-steroidal anti-inflammatory drug, this medication can not be drunk on an empty stomach, so you should use the medication after the instructions 2 times a day after the meal.

Nimesil tablets - instructions for use are very simple, but it should be noted that the medicine has adverse effect on the gastric mucosa, which, if improperly dosed, can lead to an ulcer or gastritis.

The interval between doses should be at least 12 hours. For a child over 12 years of age, the method of administration does not differ from adults.

.

For children under 12 years of age, the medicine is contraindicated. The doctor can adjust the number of tablets depending on the severity of the disease, the general condition of the patient.

.

The therapy regimen should be appointed by a specialist.

The doctor after consultation should explain to the patient how to accept Nimesil in bags. Granules of the suspension do not dissolve completely in water, give color and a pleasant (lemon) taste. There is nothing difficult in how to grow Nimesil in powder from bags:

1. Prepare 100 ml of warm water.
2. Open one packet of medicine.
3. Pour the contents (about 100 mg) into a liquid and stir well.
4. Wait 2-3 minutes and drink medication. Do not store the solution.
5. To reduce the risk of ulcers or gastritis, the use of medication should be strictly after a meal.
6. The daily dose of the drug should not exceed 200 mg. The dose can be increased to 300 mg in the first days of the disease, if the medicine is the basis of treatment.

With colds

This type of medicine is used to treat infections of an infectious, inflammatory nature. Nimesil for colds, influenza is a good choice, because it has a complex effect on the body:

• pain reliever;
• anti-inflammatory;
• antipyretic.

This makes Nimesil a suitable option for the treatment of influenza, ARVI, which are accompanied by fever, a strong pain syndrome.

Analgesic substances in the composition effectively suppress muscle, headache.

The drug will help to get rid of the patient from general weakness, febrile state, reduce the temperature, ease the condition with a wet and painful cough.

Allowed for taking the instructions in tablets or sachets (powder). Dosage is prescribed by a doctor, as a rule, it is 1 packet (100 mg) every 12 hours.

It is important to drink the remedy only after eating, the course of therapy should not be longer than 15 days. If during this time to bring the temperature to normal values ​​failed, it indicates the ineffectiveness of treatment.

With ARVI, Nimesil's intake does not exceed 4 days according to the instructions.

Children

A child can drink this medication if he is over 12 years old. Nimesil for children under 12 years is prohibited by instruction from the manufacturer.

The drug has a strong effect, and doctors recommend taking it in case analogues and other drugs do not give the desired improvement in the condition.

To minimize the occurrence of side effects, the smallest permissible dose and duration of administration are prescribed. In all other respects, the method of application does not differ from that for adults.

With cystitis

Prescribing this non-steroidal anti-inflammatory drug doctors can with bladder disease, because its use quickly helps to cope with the inflammatory process.

Nimesil with cystitis for men and girls should be prescribed only after careful examination by a specialist anamnesis, because the medication has a number of serious contraindications, for example, if there is a violation of the function of the digestive tract, liver.

Nimesil - the instruction indicates a dosage of 100 mg (1 sachet) per day. To reduce the effect of the active substance on the walls of the stomach, take the drug after eating.

The course of cystitis treatment should not exceed 2 weeks.

With menstrual pain

At some girls monthly are accompanied by a rise in temperature, serious unpleasant sensations. Nimesil with menstrual pain helps to cope with these symptoms. The medication is available in tablets, granules or powder.

For convenience of reception it is better to use sachets, the contents of which dissolve in warm water.

To 100 ml of liquid you need to pour 100 mg of substance and immediately drink Nimesil - instructions for use indicates the possible side effects associated with the gastrointestinal tract, so the use of the drug should be immediately after meal.

With genyantritis

This disease is often accompanied by severe headaches due to an inflammatory process that occurs in the sinuses. Nimesil with genyantritis is prescribed to stop unpleasant sensations.

For this, any non-steroidal anti-inflammatory drugs are suitable. They have an impact on the focus of the disease, reduce the severity of inflammation, puffiness.

The drug lowers the tension in the sinuses, which helps reduce pain.

.

Nimesil and its analogs are better than other drugs to cope with pain relief. It is not recommended to use the medicine in the presence of ulcerative, erosive lesions of the gastrointestinal tract.

.

It is strictly forbidden to drink alcohol during therapy, because there is no compatibility with Nimesil.

One of the side effects of such a violation is the appearance of erosive changes, their deterioration.

Analogues

This drug has a strong effect and in some cases, doctors suggest to replace it with more sparing drugs.

Sometimes they have a lower price, and the effect is the same. Nimesil and analogues have the same action, so they can be interchangeable.

You can order from the catalog the following analogues:

• Nyz;
• Nemux;
• Nimesulide;
• Aponil;
• Nimulid;
• Nimesan;
• Aulin;
• Nimegesic;
• Pentalgin;
• Mesulide;
• Prolid;
• The Kostral;
• Niminka;
• Aponyl.

Contraindications

Each potent substance has a number of prohibitions, the violation of which can lead to complications and side effects. So, for example, taking Nimesil during pregnancy and lactation is prohibited. According to the instructions, the use of the medication is not allowed:

• in the postoperative period after coronary bypass surgery;
• with bronchospasm, rhinitis, urticaria;
• when Nimesil is combined with other non-steroidal anti-inflammatory drugs, analgesics (eg with paracetamol);
• with a negative response from the liver to the drug;
• in the presence of inflammation of the intestine (stage of exacerbation of ulcerative colitis);
• if the fever started because of an infectious disease;
• child up to 12 years;
• if there is a bleeding GIT or an ulcer in the anamnesis;
• hyperkalemia;
• with violations of blood clotting;
• during pregnancy, lactation;
• combine with naroktikami, alcohol;
• in the presence of cerebrovascular vascular bleeding;
• with renal, hepatic, heart failure;
• if there is an individual intolerance of substances in the composition of Nimesil;
• if there is an ulcer of 12 duodenum, stomach at the stage of exacerbation.

Price for Nimesil

On how much Nimesil costs, the place of purchase, the form of release or the amount of the medicine affects. For example, you can take an inexpensive one sachet or immediately 30.

Buy this online store is not possible, except the virtual representation of pharmacies. Nimesil is released without a prescription, more often people get the option in powder, because it is easy to dilute in water.

The price of a medication may vary depending on the manufacturer's company, the region of sale. The cost of Nimesil is approximately:

• granules 1 pc. (sachet) 100 mg - the price of 23 rubles;
• powder, 30 pcs., 100 mg - price 700 r.

Reviews

A source: http://vrachmedik.ru/519-nimesil-instruktsiya-po-primeneniyu.html

Nimesil - an effective analgesic for osteochondrosis

Patients with osteochondrosis are familiar with the pain, a constant companion of this disease. Without taking pain medications, an acute attack does not recede.

To get rid of pain, in addition to conventional analgesics, use complex medications that give an anesthetic, anti-inflammatory and antipyretic effect.

One of the most popular and effective in the line of drugs with this effect is Nimesil

Description of the preparation

According to the pharmacological heading, Nimesil belongs to medicinal products used in the therapy of muscle and joint pain syndrome

Nimesil is one of the brand-name preparations of the German pharmaceutical corporation Berlin-Chemie. The right, production, sale of this medicine belongs only to this concern.

"Berlin-Chemie known on the world pharmaceutical market since 1918, developed Nimesil on the basis of its own research and testing.

Nimesil has won the pharmaceutical market, and today it is sold in more than 120 countries around the world.

In the territory of the post-Soviet states, the Nimesil medicinal product has been sold since 2000.

Active basis of the drug is nimesulide - an anesthetic, anti-inflammatory, antipyretic component.

The nimesulide group belongs to the new generation of drugs. Today they are considered to be among the most effective.

They have a minimal amount of undesirable side effects.

Due to a wide range of medicinal properties of nimesulide, it is possible to apply it in various fields of medicine: surgery, traumatology, rheumatology, dentistry, gynecology.

to the content ↑

The drug for osteochondrosis

Medicines from the non-steroid group with the inflammatory effect form part of the complex therapy of osteochondrosis.

Nimesil is administered orally in order to stop pain syndrome with an average degree in the acute or subacute phase of the disease.

Means of the nimesulide group have undergone a number of clinical trials, and it has been shown that they also have a satisfactory chondroprotective effect.

to the content ↑

pharmachologic effect

The drug Nimesil does not possess cumulative properties, is completely eliminated from the body.

The drug Nimesil is absorbed in the small intestine, manifests its effect after 30-40 minutes.

The peak of Nimesil concentration reaches about 2 hours later. The half-life of the drug is 5 hours.

How does the drug work:

1. blocks special enzymes that respond in the body for an anti-inflammatory response;
2. stop the synthesis of toxic compounds in inflammation;
3. reduces the activity of receptors responsible for the passage of a pain impulse;
4. acts oppressively on prostaglandins, - the cause of inflammatory edema.

Nimesil does not depress the central and peripheral parts of the nervous system. To the content ↑

Composition and form of release

The drug is produced in a powdery structure

The basis of the drug is nimesulide.

As an auxiliary component, the preparation was supplemented with macrogol with cetostearyl ether, maltodextrin, sucrose, citric acid, citrus flavor.

Nimesil in the dosage form is a granulate - a soluble powdery structure of a light yellow hue, from which immediately before ingestion a suspension is prepared.

The granulate is packaged in special three-layer paper sachets of 2 grams (dosage for a single dose).

One sachet with granulate contains 100 mg of the active component of nimesulide. To the content ↑

Indications for use

Nimesil is a medicinal product that is used in the symptomatic treatment of joint and muscle pain.

The main task that Nimesil performs is to stop the inflammatory process, to eliminate pain, to achieve reduction of edema at the time of application.

The intake of Nimesil's drug is indicated in the symptomatic therapy of the pain syndrome caused by osteochondrosis.

The drug Nimesil effectively acts to stop the pain caused by the inflammatory process. The drug is actively used in the postoperative period.

.

Anti-inflammatory, anti-edematous property of Nimesil minimizes or completely suppresses the inflammatory processes of the upper respiratory tract.

.

The property of the drug Nimesil rapidly anesthetize is most often used for pain with a paroxysmal character, regardless of their origin.

to the content ↑

Contraindications

The drug Nimesil is not prescribed for treatment in pediatric practice. According to special indications Nimesil is allowed to use patients who have reached the age of 12 years.

The drug Nimesil is forbidden to patients suffering from serious disorders in the work of the liver, kidneys, erosions and ulceration.

Contraindications for the use of the drug also include diabetes mellitus.

It is forbidden to take Nimesil to patients who have a history of manifestations of bronchospasm, allergic rhinitis, urticaria, which arose against the background of the use of non-steroidal anti-inflammatory drugs group.

The drug is not used in the following combinations:

1. Nimesil and paracetamol;
2. Nimesil and preparations of the group of analgesics;
3. Nimesil and other anti-inflammatory drugs of the non-steroid group.

For the treatment of which diseases and at what stage the drug is not used:

• bowel disease of inflammatory nature in an aggravated stage;
• postoperative period for aortocoronary bypass;
• febrile state against the background of inflammatory diseases with infectious nature;
• complete or partial combination of bronchial asthma with recurrent polyposis of the sinuses of the nose, paranasal sinuses;
• ulcerative lesions of the gastrointestinal tract in the aggravated stage;
• cerebrovascular vascular bleeding, tendency to bleeding and hemorrhage;
• cardiovascular insufficiency of a serious degree;
• toxic liver damage;
• alcoholism, drug addiction.

The drug Nimesil is not used in the treatment of patients if they have a hypersensitivity to any of the components in the composition. To the contents of ↑

Side effects

If you distribute the frequency and frequency of side effects of the drug in frequency, then this list will look like this:

1. Frequently occurring side effects (from 1 to 10 cases out of 100). These are symptoms in the form of nausea, dyspepsia, abnormalities in the biochemical performance of the liver.
2. Infrequent side effects (from 1 to 10 cases out of 1000). Symptoms: attacks of dizziness, constipation, hypertension, allergic manifestations on the skin surface (rashes, redness, itching, burning), vasomotor rhinitis, sweating, swelling of the face and extremities, weakness, asthenia.
3. Rare, very rare side effects (from 1 to 10 cases out of 1, 00-10, 00). Against the background of taking the drug, attacks of anxiety, cephalalgia, tachycardia, lethargy, a feeling of heat and hot flashes, lowering body temperature, angioedema, cholestasis, manifestations of encephalopathy, hepatitis, jaundice.

Non-observance of recommended dosages can cause dyspepsia, apathy, epigastric pain, attacks of suffocation, persistent hypertension

The drug Nimesil belongs to the group of drugs of the new generation.

If the Nimesil drug is used for its intended purpose, with clear recommendations for dosage, rate treatment, then its effect on the body and function is low-toxic, the number of cases of adverse events is minimal.

If the allowable therapeutic dose of the drug has been exceeded slightly, then the symptoms of overdose are eliminated by symptomatic treatment.

A patient with symptoms of an overdose is prescribed gastric lavage, intake of enterosorbents.

to the content ↑

Instruction and method of application

For effective treatment, with the minimum likelihood of adverse events, the Nimesil drug should be taken under the mandatory rules:

1. minimally effective dosage of the drug;
2. minimally short period of drug use;
3. health status monitoring;
4. if the positive effect is not achieved, the drug should be discarded.

to the content ↑

How to dilute Nimesil in powder

In one sachet of the Nimesil drug, one dose (with the main active substance nimesulide, 100 mg).

To make a suspension, take ½ cup of clean water at room temperature, pour in the contents of the sachet and mix thoroughly.

Do not use too hot or cold water.

At the bottom of the glass there should be no undissolved particles. The suspension is ready for use.

.

Keep the prepared suspension Nimesil not, so it should be prepared immediately before use.

.

about how to properly dilute Nimesil

In a day it is allowed to take 2 suspensions of Nimesil, preferably after a meal.

The course of treatment with Nimesil should not last more than two weeks.

to the content ↑

Instructions for the use of tablets

Nimesil is a medicinal product, which is produced exclusively in the form of a granulate for the preparation of a suspension.

The tablet form is available for analog preparations according to the determining component nimesulide:

1. Aponyl is a white, flat, round tablet containing 100 mg of the main active ingredient.
2. Naise is a white, yellowish-tinted biconvex round tablet with a smooth surface. The drug contains 100 mg of the main active substance.
3. Nimulide - pill is pale yellow, biconvex, rounded. The drug contains 100 mg of the main active substance.

Photo preparations:

Nimulide AponylNise

All tablet forms with nimesulide base are taken after or during meals, washed down with a small amount of clean water at room temperature. Dosages, the course of treatment in tablets are identical to Nimesil granulate.

The difference between tablets and granules at the time of onset of action. The suspension on the basis of granulate begins to act after 15-20 minutes, and the tablet form - after 30-40 minutes after ingestion. To the content ↑

Nimesil during pregnancy

Women who are in a state of pregnancy, breast-feeding, take medicines based on nimesulide is prohibited.

Treatment with nimesulide can lead to negative consequences for intrauterine development of the fetus.

This may be premature closure of the arterial duct, pulmonary arterial hypertension. Nimesil can cause intrauterine renal, hepatic pathology, lack of hydration.

In the female body during pregnancy, the Nimesil drug may provoke uterine bleeding, peripheral edema, weakening of labor. To the contents ↑

The price of the drug

Name of the drugPrice purchaseA pharmacy

Nimesilgrunuly 100mg / 2g 1pc	from 24 rubles.	Buy
Nimesilgrunuly 100mg / 2g 1pc	from 27 rubles.	Buy
Nimesilgrunuly 100mg / 2g 30pcs	from 734 rubles.	Buy
Nimesilgrunuly 100mg / 2g 30pcs	from 810 rubles.	Buy

to the content ↑

Analogs Substitutes

To full-fledged analogs (synonymous drugs) Nimesil all medicinal substances belong, where the main active component is nimesulide. Analogues can be presented in granules, tablets, powders.

Analogues of Nimesil are manufactured by various pharmaceutical companies. The technological processes that they use in production are insignificant, but differ. Therefore, bioavailability, the severity of clinical effects, the incidence of adverse reactions is not excluded.

The most famous analogues of Nimesil are:

1. Nimesulide in tablets. Produced in Macedonia Replekpharm AD, the Russian pharmaceutical enterprises Obolenskoe, Berezovsky, Ozon, Izvarino-Pharma.
2. Nemusle granulate. Manufacturer: Romanian pharmaceutical company Replekpharm AD.
3. Floiled granulate. Produced by the Italian pharmaceutical concern Laboratorio Farmaceutico.
4. Nimesulide Teva in tablets. Manufacturer: Portuguese pharmaceutical company Bluepharma Industria.

Photo gallery of analogues:

Nimesulide TevaNemuxlex Nimesulide

At the end of 2013, a new analogue of Nimesil, the Affidad Fort, appeared on the pharmaceutical market.

A medicinal preparation, a complete analog (according to the main active ingredient and according to the dosage form) is issued as a granulate for the preparation of a suspension.

The new drug is manufactured by the Swiss pharmaceutical company Schonen.

to the content ↑

Reviews

Christina, 29 years old: Nimesil is a powder for all occasions. He helps me with headaches, toothaches. Nimesil well knocks down the heat.

After applying side effects did not feel, but more than two days did not take it. I have a stomach ulcer, but after taking nimes, I do not feel any discomfort and pain in my stomach.

Nimesil is pleasant to drink, it really starts to act in just 15 minutes.

Philippe, 22 years old: The drug is really good. My father often suffers from a back, and this anesthetic is the only thing that helps with exacerbation of osteochondrosis. So nimesil - "first aid" with back pain and before going to the doctor.

A source: http://OsteohondrozInfo.com/preparaty/nimesil

Nimesil: instructions for use

Powder Nimesil belongs to the group of medicines, nonsteroidal anti-inflammatory drugs. It is a chemical derivative of sulfonanilides. The drug is used to reduce the severity of the inflammatory reaction and its manifestations in various pathologies.

Form of issue, composition

The drug Nimesil is available in the form of a powder for the preparation of a suspension, which is intended for oral administration.

It has a light green color, coarse grain and an orange smell. The main active ingredient of the drug is nimesulide, its content in 1 packet of powder is 100 mg.

Also, the preparation contains additional compounds, which include:

• Sucrose.
• Orange flavor.
• Ketomacrogol.
• Anhydrous citric acid.
• Maltodextrin.

Powder Nimesil is packaged in bags of aluminum foil to 2 g. The cardboard pack contains 9, 15 or 30 bags.

Act

The active component of Nimesil powder refers to the selective antagonists of the enzyme COX-2 (cyclooxygenase-2), which suppresses its activity.

COX-2 catalyzes the reaction of the conversion of arachidonic acid to the main mediators of the inflammatory reaction prostaglandins, which are synthesized by cells of the immune system in response to the development of pathological process.

A decrease in the concentration of prostaglandins leads to a decrease in the manifestations of the inflammatory reaction, which include pain (prostaglandins irritate sensitive nerve endings), edema of tissues (the outlet of the liquid part of the blood from the vascular bed into the intercellular substance of the tissues), as well as blood stasis in the vessels of the microcirculatory channel.

Nimesulide is metabolized predominantly in the liver with the formation of inactive products that are excreted in the urine.

The half-life (the time taken to excrete half of the entire dose of medication) for nimesulide is about 6 hours.

Indications

The reception of a suspension prepared from Nimesil powder is indicated to reduce the severity of the inflammatory reaction and pain in certain diseases, which include:

• Back pain, lower back, which has an inflammatory origin.
• Various pathological processes in the structures of the musculoskeletal system, which include the transferred injuries, inflammation of the ligaments (tendinitis), sprains, dislocations and subluxations of various joints.
• Toothache.
• Headache of various origins, including migraine of medium severity.
• Painful menstruation in women (dalgomenorrhea).

The drug is intended only for symptomatic and pathogenetic treatment of pain and inflammatory syndrome. It does not affect the underlying cause of the pathological process.

Contraindications

Nimesil powder can not be taken if a person has certain pathological processes or physiological conditions, which include:

• A peptic ulcer characterized by a violation of the integrity of the mucous membrane of the stomach or duodenum. This is due to the fact that the drug Nimesil partially reduces the level of prostaglandins, which are responsible for protection mucous membrane of the upper gastrointestinal tract from aggressive factors (gastric acid of gastric juice).
• Postponed in the past gastrointestinal bleeding, including against the background of peptic ulcer.
• Noninfectious inflammatory chronic intestinal diseases in the acute stage (ulcerative colitis).
• Feverish conditions, accompanied by an increase in body temperature, in particular in acute respiratory viral pathology, bacterial infections.
• Presence of allergic diseases, including a combination of polynomia, bronchial asthma, and intolerance to acetylsalicylic acid, which is a non-steroidal anti-inflammatory facilities.
• Increased sensitivity (hypersensitivity) of the body to acetylsalicylic acid, including transferred in the past and accompanied by spasm of bronchi (allergic bronchitis), inflammation of the nasal mucosa, hives.
• Restorative period after surgical intervention aorto-coronary bypass.
• The presence in the anamnesis of diseases accompanied by increased hemorrhage, hemorrhagic stroke of the brain.
• Severe disorders, accompanied by a violation of blood clotting (a decrease in the functional activity of the hemostasis system).
• A marked decrease in the functional activity of the heart (severe heart failure).
• Joint use of drugs that have a negative effect on the liver (hepatotoxic drugs).
• Severe renal or hepatic insufficiency.
• Chronic alcoholism or drug dependence.
• Pregnancy or the period of breastfeeding (lactation) in a woman.
• The patient's age is less than 12 years.
• Individual intolerance to any of the components of the drug.

With care, Nimesil powder is used with concomitant diabetes mellitus type 2, high blood pressure (arterial hypertension), coronary heart disease, peripheral arterial pathology, smoking, concomitant use of drugs that reduce blood clotting (non-steroidal anti-inflammatory drugs, clopidogrel, heparin and its analogs), as well as hormone anti-inflammatory drugs (glucocorticosteroids).

How to grow Nimesil powder?

Powder Nimesil is used for the preparation of a suspension that is taken orally. One packet is dissolved in 1 glass of water with a volume of 100 ml. The prepared suspension should be immediately applied, it is not subject to storage.

The average therapeutic dosage is 100 mg of nimesulide (1 sachet) 2 times a day. The maximum duration of the course of therapy with Nimesil powder should not exceed 15 days.

Correction dosages for adolescents over 12 years, the elderly, as well as patients with concomitant, moderate renal failure are usually not required.

Side effects

Against the background of taking a suspension prepared from Nimesil powder, it is possible to develop negative reactions from various organs and systems:

• The digestive system - nausea, periodic vomiting, diarrhea (diarrhea). Rarely, abdominal pain, constipation, bloating (flatulence), signs of bleeding from the structures of the gastrointestinal tract in the form of degteobraznogo dark stool.
• Cardiovascular system - increased blood pressure, heart rate (tachycardia), sensation of hot flashes.
• Nervous system - dizziness, rarely develops headache, nervousness of a person, nightmarish dreams, a sense of fear.
• The liver and biliary tract - inflammation of the liver (hepatitis), which very rarely can have a lightning form, development jaundice, increased activity of hepatic enzymes (ALT, AST) in the blood, indicating damage to liver cells (hepatocytes).
• The system of breathing - shortness of breath, very rarely possible exacerbation of bronchial asthma.
• Urinary system - rarely blood can appear in the urine (hematuria), while urination itself becomes painful (dysuria).
• Organs of the senses - impaired vision.
• The system of blood and red bone marrow is anemia (anemia), an increase in the number of eosinophils (eosinophilia), a decrease in the number of thrombocytes (thrombocytopenia) in the blood.
• Allergic reactions - itching, rash on the skin, excessive sweating, less likely to develop urticaria (changes on the skin that resemble a nettle burn), anaphylactoid reactions with expressed edema of peripheral tissues (angioedema) or a critical decrease in the level of systemic arterial pressure with multiple organ failure (anaphylactic shock).

The appearance of any of the signs of the development of side effects after the start of the suspension, prepared from Nimesil powder, is the basis for drug discontinuation.

Features

Before starting the suspension, prepared from Nimesil powder, it is important to carefully read the instructions to the medication. There are several features of the correct use of the drug, which include:

• The active substance of the drug can interact with drugs from other pharmacological groups, so when using them, you should consult a medical professional.
• The likelihood of developing negative reactions decreases with the use of the drug at a minimal course in an effective minimum dosage.
• Inadequate kidneys of moderate severity require reducing the dosage of Nimesil powder.
• The auxiliary component of the preparation is sucrose, which is necessarily taken into account when prescribing to patients with concomitant diabetes mellitus.
• Do not take Nimesil powder at the same time as other non-steroidal anti-inflammatory medications.
• The effect of the drug on the functional activity of the central nervous system has not been reliably studied, therefore, Nimesil powder is recommended to be cautious when doing activities that involve the need for sufficient speed reactions.

In the chemist's network, Nimesil powder is dispensed by prescription. It is not recommended to take the drug yourself without proper prescription.

Overdose

A significant excess of the recommended therapeutic dosage of Nimesil powder is accompanied by the appearance of nausea, accompanied by a periodic vomiting, apathy, drowsiness, abdominal pain, more pronounced in the stomach (upper abdomen or epigastrium), gastrointestinal bleeding. Treatment of overdose is carried out in the conditions of a medical institution. It is symptomatic, as there is no specific antidote for today. Washing of the stomach, intestines, intestinal sorbents (activated carbon, Smecta, Enterosgel) is performed.

Analogues

The composition and therapeutic effects for Nimesil are similar drugs Nimesulid, Nyz, Nemulks.

Storage

The shelf life of Nimesil powder is 2 years. Suspension prepared from powder is not subject to storage. The drug should be stored in a dark, dry place inaccessible to children at an air temperature of no higher than 25 ° C.

Nimesil price

The average cost of packing Nimesil powder, containing 30 bags, in pharmacies in Moscow varies between 690-710 rubles.

A source: http://bezboleznej.ru/nimesil