Angiosyl retard - a preparation of the group of antihypoxants, which improves the utilization of oxygen circulating in the body, and increasing resistance to oxygen deficiency (hypoxia), directly affecting the neurons of the brain and cardiomyocytes, optimizing their metabolism and function.
On this page you will find all information about Angiosyl retard: the full instructions for use for this medicine medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Angiosyl retard. Want to leave your opinion? Please write in the comments.
Clinical and pharmacological group
Trimetazidine has an antihypoxic effect. Directly affecting the cardiomyocytes and neurons of the brain, it optimizes their metabolism and function.
Conditions of leave from pharmacies
It is released on prescription.
Price list
How much does Angiosyl retard? The average price in pharmacies is at the level of400 rubles.
.Form of issue and composition
The preparation is available in the form of biconvex tablets, which have a round shape and are covered with a pink coating. It is packed into contour packs, each of which accommodates 10 pcs. or 14 pcs. tablets. Boxes are made of cardboard.
1 tablet Angiozil retard contains trimetazidine dihydrochloride in an amount of 35 mg. Additional ingredients include:
- colloidal silicon dioxide;
- iron oxide (yellow and red);
- microcrystalline cellulose;
- macrogol;
- polydextrose;
- lactose monohydrate;
- hypromellose;
- titanium dioxide;
- magnesium stearate.
Pharmacological effect
A drug that improves the metabolism of the myocardium and neurosensory organs under conditions of ischemia. Has antianginal, antihypoxic effect. Directly affecting the cardiomyocytes and neurons of the brain, it optimizes their metabolism and function. The cytoprotective effect is due to an increase in the energy potential, activation of the oxidative decarboxylation and rationalization of oxygen consumption (increased aerobic glycolysis and oxidation blockade fatty acids). Supports contractility of the myocardium, prevents the decrease in intracellular content of ATP and phosphocreatinine.
In conditions of acidosis normalizes the functioning of membrane ion channels, prevents the accumulation of calcium and sodium in cardiomyocytes, normalizes the intracellular content of potassium ions. Reduces intracellular acidosis and phosphate content due to myocardial ischemia and reperfusion. Prevents the damaging effect of free radicals, preserves the integrity of cell membranes, prevents the activation of neutrophils in the zone ischemia, increases the duration of the electrical potential, reduces the output of CKK from cells and the severity of ischemic damage myocardium.
With angina reduces the frequency of seizures (while reducing the consumption of nitrates). After 2 weeks of treatment, tolerance to physical activity increases, blood pressure drops decrease. Against the background of the use of the drug in patients, hearing and vestibular samples improve, dizziness and tinnitus decrease.
In the vascular pathology of the eyes, the functional activity of the retina is restored when the drug is used.
Indications for use
- Cohleo-vestibular disorders, which have ischemic etiology. This includes tinnitus, dizziness, hearing loss.
- Chorioretinal vascular disorders.
- Angina pectoris (as part of complex therapy).
Contraindications
Hypersensitivity to the drug, deficiency of lactase,renal insufficiency, liver disease, lactose intolerance, age under 18, pregnancy, lactation.
Application in pregnancy and lactation
During the period of gestation and breastfeeding, the use of angiosyl retard is contraindicated.
Instructions for use Angiosyl retard
In the instructions for use indicated that Angiosyl retard appoint 1 tab. (35 mg) 2 times / day during meals in the morning and evening. The duration of therapy is set individually.
Side effects
In some cases, patients taking Angiozil Retard tablets may experience side effects in the form of dizziness and headache, dyspepsia, pain in the abdomen, nausea and vomiting, skin rash and itching, as well as orthostatic hypotension.
When using these tablets, it is important to consider that they have little effect on the ability to drive motor transport, as well as to perform some actions that require increased psychomotor reactions.
Overdose
To date, cases of overdoses due to the use of angiosyl retard have not been documented.
special instructions
Trimetazidine is not used for arresting angina attacks, it is recommended to reconsider and adapt the therapy when developing a heart attack.
Do not use the drug in the initial course of treatment of myocardial infarction or unstable angina.
Due to the lack of data from clinical trials on the use of the drug in severe liver disorders, it is not recommended to prescribe antihypoxic drugs for this category of patients.
Angiozil retard on the ability to drive vehicles and perform work that requires increased concentration and speed of psychomotor reactions, affects slightly.
Reviews
The medicinal preparation of Angiosyl Retard is highly effective in the treatment of coronary heart disease, as evidenced by numerous positive responses from doctors and patients.
Patients who took these pills noted their ability to quickly stop angina attacks, as well as normalize blood pressure. In some cases, after taking the drug, weakness and lethargy are observed, therefore it is undesirable to drive the car independently during the therapeutic course. According to reviews of patients, side effects from the use of these tablets are extremely rare. Patients are noted and a positive effect on hearing organs with ENT diseases.
According to doctors, as a result of taking Angiozil Retard patients with CHD with heart rhythm disturbances twice a day at a dose of 35 mg in combination with antianginal therapy for one month significantly reduced the number of ventricular extrasystoles and episodes of supraventricular paroxysmal tachycardia.
Analogues
The analogues of Angiosyl retard are: Antistene, Depenorm MB, Vero-Trimetazidine, Preductal, Preductal MB, Medarum 20, Trimetazide, Trimet, Trimectal, Trimectal MB, Trimetazidine, Trimetazidine MV, Rimecor.
Before using analogues, consult your doctor.
Storage conditions and shelf life
Angiosyl retard should be stored in a cool (not more than 25 ° C) and protected from light place, which is hard to reach for children. Shelf life is 4 years. Do not use the drug after the expiration date, which is indicated on the package.
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