Lorinden C

Lorinden is a means of the last generation, which copes well with numerous external lesions of inflammatory, infectious and fungal nature.

It is also relevant for cases that are accompanied by hyperkeratosis and periodic itching. Lorinden C is also used against seborrheic and atopic dermatitis, allergic contact dermatitis, red flat lichen, cutaneous forms of lupus erythematosus, polymorphic erythema.

The drug has three main varieties, each of which has certain healing properties and can be used in the treatment of a number of specific skin diseases.

Clinical and pharmacological group

The drug with antibacterial, antifungal and anti-inflammatory effect for external use.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much is Lorinden S? The average price in pharmacies is at the level of400 rubles.

Form of issue and composition

There are two types of Lorinden's preparation - ointment A and C.

The first is an anti-inflammatory drug with keratolytic action for use in external purposes. The second serves as an antibacterial agent with an antifungal, anti-inflammatory effect, and is also used topically for allergic diseases. Both drugs contain flumethasone in the form of a pivalate salt.

instagram viewer

Two formats of Lorinden's ointment differ in composition and function. Detailed description of each:

Ointment C	Ointment A
Description	Oily ointment of white with yellow or gray shades	Oily soft ointment of white color with a yellow tinge
The concentration of flumethasone pivalate, μg per g	200	200
Concentration of clioquinol, mg per 1 ml	30	0
Concentration of salicylic acid, mg per 1 g	0	30
Composition	Beeswax wax, petroleum jelly	Lanolin, propylene glycol, petrolatum
Packaging	Aluminum tubes of 15 g in a cardboard box with instructions for use

Pharmacological effect

The drug has antibacterial, antifungal and anti-inflammatory effects for external use.

Clioquinol (iodochlorooxyquinoline) is active against dermatophytes, yeast fungi and gram-positive bacteria. Enhances the antiexudative effect of flumethasone.
Flumethasone has anti-inflammatory, anti-allergic, antipruritic, decongestant and vasoconstrictive effects. Reduces inflammatory exudate and production of lymphokines, inhibits the migration of macrophages, reduces infiltration and granulation. Reduces the production of prostaglandins and leukotrienes. The drug causes reduction of the main substance of connective tissue, weakens proliferative and exudative reactions in the skin.

Active components in the interaction inhibit the development of inflammatory-allergic reactions from the skin, complicated by bacterial and fungal infection. The fatty base has a softening effect, creates a waterproof protective film on the skin surface, so that the drug can be used in patients with dry and thin skin.

Indications for use

According to the data specified in the instructions for Lorinden A, this drug is intended for the treatment of acute and chronic allergic dermatoses, especially those accompanied by excessive cornification of the skin. In particular, it is used when:

Psoriasis;
Red warty deprive;
Photodermatitis;
Red plane deprive;
Paws with severe lichenization (densification and roughness of the skin);
Multiforme exudative erythema;
Bubble skin diseases (as part of combination therapy);
Discoid lupus erythematosus;
Atopic dermatitis;
Chronic liar of Vidal;
Diffuse neurodermatitis;
Hyperkeratosis;
Seborrhea;
Various forms of chronic and subacute eczema (especially horny);
Chronic dyshydrosis;
External otitis;
Insect bites.

Contraindications

Loriden C is contraindicated in the following cases:

trophic ulcers of the shins caused by varicose veins;
precancerous conditions and neoplasms of the skin (atheroma, nevus, skin cancer, hemangioma, melanoma, xanthoma, epithelioma, sarcoma);
dermal post-vaccination reactions;
pink and acne vulgaris;
cutaneous symptoms of syphilis;
lupus;
perioral dermatitis;
skin infections;
viral skin diseases (chicken pox, herpes);
the first trimester of pregnancy;
children's age till 10 years;
individual intolerance of active substances or auxiliary components.

With caution appoint the drug during pregnancy in the second and third trimester, as well as during breastfeeding.

Use in pregnancy and lactation

Care should be taken during the period of bearing of the child: although the active substance does not accumulate in the skin and does not penetrate the placental barrier, it is necessary to monitor the treatment process. Lactation is also not an obstacle to the use of Loriden: the absence of its penetration into breast milk allows without the fear for the health of the baby to use this drug.

Dosage and route of administration

The instructions for use indicate that the Lorinden C Ointment is applied a thin layer on the skin in the affected area. At the beginning of therapy the drug should not be used more often 2-3 times / day; when there is a positive dynamics 1-2 times / day.

The drug should not be used for more than 2 weeks.
It is not recommended to apply a day more than 2 g of ointment.
If it is necessary to use a bandage, a bandage that passes air should be used. With excessive lichenization and hyperkeratosis, ointment is used only under the occlusive dressing once every 24-48 hours. In this case, the duration of the drug is no more than 1 week.

In children and adolescents older than 10 years, the drug can be used only in exceptional cases in limited areas of the skin and avoid applying ointment to the skin of the face.

Side effects

During the application of Lorinden C, there may be side effects in the form of acne, dry skin, atrophy of subcutaneous fat, alopecia, excessive hair growth, discoloration or hyperemia of the skin, perioral dermatitis, inflammation of the hair follicles or disruption of the integrity of the skin.

In the case of Lorinden C with an occlusive dressing, the risk of systemic side effects increases, for example, hypertension, swelling, or secondary infection.

Overdose

With prolonged use of the drug in excessive doses, an overdose is possible. Its symptoms can be a sharp increase in the side effects of the drug. There is no specific treatment for Lorinden C overdose. Symptomatic treatment is recommended.

special instructions

Before you start using the drug, read the special instructions:

Apply Lorinden C to the skin is not recommended, and you should avoid getting the ointment in the eyes.
With prolonged therapy, it is possible to develop resistance of the microflora to the action of the active substance of the preparation (clioquinol).
Use the drug for longer than the recommended period should not be, since the long-term use of Lorindin C on extensive areas of the skin increases the risk of systemic side effects of glucocorticosteroids.
With atrophic skin changes, especially in elderly patients, Lorinden C should be used with caution.
In fungal diseases with secondary allergic reactions, ointment should be used under medical supervision in exceptional cases.
In cases of development of secondary infections at the site of application of the drug, it is necessary to use drugs with more pronounced antifungal or antibacterial action.

Drug Interactions

Due to the fact that Lorinden C has an immunosuppressive effect, immunization and vaccination can not be performed during treatment.

Ointment should not be prescribed concomitantly with other topical medicines.

Flumethasone reduces the effectiveness of anticoagulants, antihypertensive and hypoglycemic drugs, reduces the concentration of praziquantel and salicylates in the blood serum.

In the case of combined use, Lorinden C increases the risk of side effects of the following drugs: cardiac glycosides (digitalis intoxication); diuretics (hypokalemia); oral contraceptives, androgens, estrogens, anabolic steroids (hirsutism, acne); antipsychotic drugs, azathioprine, bucarban (cataract); tricyclic antidepressants, antihistamines, nitrates, holinoblokatory (glaucoma).

Reviews

We picked up some feedback from people who used Lorinden C Ointment:

Anna. At me all has turned out is banal enough: the allergy "has got out" on a washing powder (has decided new to try, on the head, more truly, arms or hand)) an itch intolerable, red maculae, an ecdysis. to the dermatologist has addressed at once, as for health I try to watch and not lead up to complications. because the sooner you take measures to eliminate the problem, the faster and easier the recovery will come. I was prescribed antihistamines, vitamins, and Lorinden S. the treatment took a little longer than a week, the skin cleared perfectly, Lorinden not only pleasantly cooled the skin, but the itch also quickly "removed", the spots with flaking subsequently also disappeared. I hope that this will not happen to me again) although I recovered quite quickly, but it is better not to get sick at all).
Elizabeth. I never thought to what extent I have sensitive skin. Especially on the hands and stomach. In childhood, there was a problem with allergic rashes from tomatoes. Then treated with iodine, and it was unpleasant. Now any irritation or pimples I treat with "Lorinden C". I like that it does not have an excessively greasy structure and a disgusting flavor. On the contrary, the smell is almost neutral, there is no color, which allows you to smear and face / lips. Blisters from allergens on the chest / neck / stomach, pryshchiki on the hands of the nerves and even the initial herpes on the lips, I treat with ointment "Lorinden C" and recommend it to everyone with sensitive skin!

Analogues

There are no complete analogues of Lorinden A and C, therefore they are unique preparations with an active complex of substances. Indirect substitutes for medicines are distinguished, similar to them according to the manifested therapeutic effect. Among them, the following preparations are popular in the form of an ointment or cream: