How to choose a cough medicine?
What are the cough tablets?
Effective drugs for cough therapy in adults, adolescents and children is an actual topic to date and this is related to common cases of self-medication and a huge choice of drugs in the form of syrups, tablets, potions, drops, suspensions, sprays, inhalers, infusions and tinctures. In this case, patients often consult a pharmacist and pharmacist who can not assess the nature of the cough, determine the diagnosis and severity disease, the possibility of a complicated course of nosological form, which can be determined only by a qualified specialist - therapist, pediatrician or family doctor. If necessary, additional instrumental methods of examination are prescribed.The correct treatment of a cough is not to suppress the cough reflex, which is a protective reaction of the body to irritation of the respiratory tract due to the development in them inflammatory process and with sputum production (wet cough) or with minimal mucus presence (dry unproductive cough), and also in case of inhalation of any irritant factor:
- small particles of dust;
- foreign objects;
- various infectious agents - pathogenic microorganisms, viruses, fungi;
- allergens.
In some cases, cough, especially in childhood, can occur in diseases that are not associated with pathological processes directly in the respiratory system, but has a central (neurogenic) nature - with neuroses, the syndrome of hyperactivity, psychopathy. Also cough is an additional symptom in diseases of other organs or systems: allergic diseases, heart and vascular diseases, digestive organs.
Therefore, in each specific case, a diagnosis and careful selection of strictly defined and maximized effective cough tablets for complex therapy of the underlying disease with elimination or relief of a specific type of cough.
Pathogenesis of cough
Mucous membranes of the trachea, bronchi and alveoli normally produce mucus.
But with inflammatory processes that occur during seasonal infections, colds, cough is one of the symptoms, acutely occurring pathological processes that accompanied by an increase in temperature, lethargy, weakness, runny nose and general malaise, in connection with the development of the inflammatory process in the epithelial cells of the larynx, trachea, pharynx, bronchi or alveoli. At the same time, hyperemia with persistent edema and production of mucous exudate develops, aimed at evacuating viruses and pathogenic microorganisms from the upper and lower respiratory tract.
Another cause of coughing is bronchospasm.
Inflammation of the alveoli, pleura, or lung tissue with pneumonia and pleurisy is accompanied by frequent dry, and irritating cough, but the diagnosis of these diseases is carried out only in the conditions of a medical institution.
Types of cough and treatment tactics
Cough, depending on the amount of sputum in the respiratory tract is divided into wet and dry.
In this case, treatment of each type of cough has its own characteristics and determines the choice of cough medicine.
Tablets from dry cough, in most cases suppress the cough reflex (blocking the cough center or the receptors of the tracheobronchial tree), so their
It is unacceptable to use for the treatment of a damp cough, as a result of which evacuation of sputum and bronchial clearance are completely blocked by a constantly developing secret.
Also, do not use tablets from wet cough, dilute sputum and promote both its formation, and an easier expectoration in the occurrence of dry cough, which is associated with irritation of the mucous membrane of the respiratory tract by a catarrhal inflammatory process or irritation with chemical or physical agents. If they are not effective, they can stimulate the secretion when the cells are not ready for it, so there is aggravation of edema and inflammation of the bronchi and trachea.
It is important to remember that cough is only a symptom of the disease and the main point of therapy is the definition and elimination of the cause of the pathological process.
Causes of cough in children and adults
To date, the main causes of coughing are:
1. Diseases of the respiratory system
- Catarrhal and infectious diseases of the bronchopulmonary system of viral and bacterial etiology (considered the largest and most important group of pathologies that are accompanied by a cough):
- diseases of the upper respiratory tract (nasopharyngitis, laryngitis, pharyngitis, laryngotracheitis, tonsillitis, sinusitis);
- pathological processes in the lower respiratory tract (tracheitis, tracheobronchitis, bronchiolitis, bronchitis, bronchopneumonia and pneumonia, pleurisy, alveolitis, lung abscess);
- Specific infectious and inflammatory processes (tuberculosis and mycosis of the lungs, chlamydial pneumonia), 3) Diseases of infectious-allergic and allergic genesis (bronchial asthma, angioedema larynx);
- Congenital pathology of bronchi and lungs (bronchial hypoplasia, congenital bronchiectasis);
- Children's infectious diseases (whooping cough, measles, scarlet fever);
- Benign and malignant neoplasms of the respiratory tract (lung sarcoma, bronchogenic carcinoma, pleural tumors);
- Irritation of mucous respiratory tract by aggressive chemical substances (poisoning with petrol vapors, acetone, carbon monoxide);
- Foreign bodies in the respiratory tract;
- Interstitial lung diseases.
2. Diseases of the heart and blood vessels
- heart defects (congenital and acquired);
- angina pectoris;
- heart failure;
- inflammatory diseases of the heart (myocarditis, pericarditis).
3. Diseases of the digestive tract
- gastroesophageal reflux;
4. Diseases of the nervous system
- neurogenic dysfunction of the pharynx musculature;
- neuroses;
- Parkinson's disease;
- organic pathology of the brain (post-stroke complications, brain tumors).
5. Other reasons
- a smoker's cough;
- cough, as a side effect when taking certain medicines (inhibitors of renin-angiotensin).
Effective elimination of the cause of the occurrence of cough, is the basis for the therapy of cough, directed at the etiologic factor.
Classification of drugs that eliminate and relieve cough
The modern classification of medical devices that affect cough is extensive, but to date the drugs are positively affecting the occurrence of cough reflex, its productivity and intensity in pharmacology and medicine are divided into three main groups:- drugs that directly exert a retarding effect on the cough center of the central nervous system (in the brain) and on the nerve endings of cough receptors with complete or partial suppression of cough;
- drugs affecting smooth muscle and bronchial mucosa;
- drugs affecting the state of bronchial secretions.
Dry cough pills
Dry cough occurs as a complex reflex protective reaction of the body, which occurs with constant irritation of the respiratory tract by any infectious or other foreign agents with simultaneous presence of catarrhal inflammation and edema of the mucous membrane of the respiratory tract with minimal production of sputum, mainly in the development of viral or bacterial infections.
Dry cough is irritating and unproductive, and most often occurs with catarrhal inflammation of the mucous membranes of the upper respiratory tract - larynx, nasopharynx and / or the initial part of the trachea, as well as their combined lesions - laryngopharyngitis, laryngotracheitis and pharyngotracheitis. Also, a frequent dry and irritating cough can occur in children with infectious diseases - measles, paracut, parotitis, whooping cough and scarlet fever.
Dry cough can be a symptom of pleurisy, bronchoadenitis, the presence of a foreign body of bronchial tubes, as well as a symptom of diseases of other systems: psychogenic cough with neuroses or irritating cough with endocrinopathies and diseases of the digestive system (gastroesophageal reflux).
In this type of cough, in a number of cases, antitussive drugs that depress the cough reflex are prescribed. It is important to remember that this type of medication is used only for the purpose of the doctor at any age, but in young children (up to a year), premature and weakened babies, in the presence of perinatal pathology of the central nervous system, these drugs can oppress not only the cough reflex, but also respiratory center. Therefore, in pediatric practice, these drugs are prescribed only under the constant supervision of a specialist in the case of severe dry cough, significantly disturbing the well-being and sleep of the child, causing regurgitation and vomiting - in whooping cough, parakoklishe and in the complex therapy of obstructive bronchitis and bronchopneumonia.
These drugs are divided:
- preparations of central action;
- peripheral action;
- combined medicines.
Counter-cough medicines of central action
A group of drugs affecting the center-center cough center is used to eliminate coughing and is used to treat diseases with no sputum. It includes mainly medicines for the treatment of dry cough:
1. With narcotic effect (Morphine chloride, Codeine, Demorphan, Hydrocodone, Codipron, and Ethylmorphine hydrochloride).
2. Without a narcotic effect (Tusuprex, Glavent, Sedotussin, Sinekod, Pakseladin, Butamirat).
Narcotic antitussive medicines
These drugs are released in the pharmacy network only when presenting a prescription.
With caution the drugs of this group are prescribed for acute pain in the abdomen of an unknown genesis, convulsions (in the anamnesis), arrhythmia, alcoholism, bouts of asthma, suicidal tendencies, neuroses and emotional lability. And also with intracranial hypertension and brain injuries of prostatic hyperplasia, renal and / or hepatic insufficiency, hypothyroidism, severe inflammatory bowel disease, and with urethral strictures channel. Very rarely drugs of this group are assigned to weakened patients, in any period of pregnancy and during lactation, and also elderly patients and children due to a large number of adverse reactions, the possibility of overdose and poisoning.
It should be noted that the use of other antitussive and expectorants simultaneously with narcotic antitussives is prohibited.
The most common drugs in this group are Codeine and codeine-containing drugs and Ethylmorphine.
Codeine
Codeine is an alkaloid of opium and is formed synthetically by methylation of morphine. Its therapeutic effect is based on suppressing the redistribution of the cough center of the brain.Codeine is part of the combination of medications that are used as symptomatic agents for the treatment of an obsessive, painful and debilitating cough:
1) in combination with expectorant drugs and terpinhydrate
- Terpinkod;
- Codterpine;
- Kodarin;
2) with sodium hydrocarbonate, a herb of thermopsis and a root of licorice
- Codesan;
- Kodelak;
3) in combination with anti-inflammatory drugs (ibuprofen, naproxen, metamizole, paracetamol and analgin, and) with the inclusion of some preparations of phenobarbital with its soothing action
- Sedalgin;
- Pentalgin;
- Solpadein;
- Nurofen Plus.
Ethylmorphine
Ethylmorphine is a central antitussive drug that promotes stimulation of opioid receptors neurons of the brain and a decrease in the excitability of the cough center and providing analgesic and soothing act. It is available in the form of tablets.Indication for use Ethylmorphine is an unproductive, painful cough that is accompanied by a pain syndrome with pulmonary tuberculosis, pleurisy, neoplasms of the bronchopulmonary system.
Contraindication to the use of this drug is respiratory depression against the background of various infectious and inflammatory processes of the lungs (bronchopneumonia, bronchiectasis, pulmonary emphysema and other COPD), especially in the elderly, as well as increased sensitivity to drug. The most frequent adverse reactions are persistent headaches, insomnia, permanent constipation (especially in the elderly and senile age, in weakened patients) and the development of drug dependencies.
Non-narcotic antitussive medications
To date, the pharmacy network has a very large selection of non-narcotic antitussive drugs, which can be considered true cough tablets. Typical representatives of this group are Libexin, Paxeladin, Glaucin, Sedotussin, Tusuprex, Sinekod and other preparations.
The mechanism of action of these drugs:
- oppressive effect on the nerve endings of cough receptors with complete or partial suppression of cough and mediated inhibition of the cough center;
- interruption or weakening of signals going to the brain (medulla oblongata) from the affected mucosa of the trachea and bronchi.
Some of these substances are part of a combination of drugs, mainly Glaucin, which is an antitussive component many medicines containing also other soothing, expectorant or anti-inflammatory components (Stoptussin, Broncholitin).
Medicinal preparations of non-narcotic effect for today by patients and in some cases also by doctors are widely used, but, to Unfortunately, it is often unreasonable and wrong, because the indication for their purpose is the need to suppress frequent, irritating cough. In pediatrics, such cases are rare - mainly with whooping cough or in cases of intense productive cough with intense production sputum with the formation of abundant and liquid bronchial secretion (bronchorrhea), when there is a real threat of aspiration of bronchial contents.
In patients in the older age group (children over 12 years, adolescents, adults), these drugs are prescribed in cases of cough, combined with moderate bronchospasm. At the same time they are used both independently and as an addition to bronchodilator drugs, suppressing catarrhal or allergic inflammation.
The most commonly prescribed drugs in this group are Butamyrate, Libexin, Bithiodine, Paxeladine.
Butamate
This antitussive drug effectively inhibits the excitability of the cough center, while providing moderate anti-inflammatory, expectorant action and a weak bronchodilator effect, reducing irritation of the trachea and bronchi and potentiating antitussive action without depressing influence on the respiratory center.Butamirate tablets are used for symptomatic treatment of inflammatory diseases of the bronchopulmonary system in adults and children and over 12 years of age who are accompanied by a frequent unproductive and severe irritating cough that has an obsessive character. Butamirate is the main component of medicines Sinekod, Kodelak-Neo, Omnitus.
Bithiodine
Antitussive drug, the therapeutic effect of which is due to active influence on the receptors of the mucous membrane of the bronchopulmonary system and to a lesser extent on the cough center of the central nervous system. Its active ingredient is Tipedidine, which is close to codeine by force of action, but does not cause drug dependence even with prolonged use.
Paxeladin
This drug refers to antitussive drugs that do not have a chemical affinity for either opioids or their derivatives, or antihistamines. Its active ingredient is oxeladine citrate, which acts selectively at the level of the cough nerve centers. Pakseladin is released in prolonged-action capsules and in syrup. Like all non-narcotic antitussives, it is prescribed for the symptomatic treatment of frequent dry cough in most cases spastic or reflex. It is not used to treat productive cough - it is difficult to get rid of phlegm and aggravation of inflammatory processes, conditions are created for the development of complications (bronchopneumonia, pleurisy). Also, do not apply Paxeladin simultaneously with expectorant and mucolytic drugs - in this case, activates viscous products sputum, which provokes the development of bronchospasm, peristalsis of small and medium bronchi and obliteration of the lumen of the bronchi, which aggravates cough.It is not recommended to use capsules before the age of 15 years.
Indications and features of non-narcotic antitussive drugs
A group of non-narcotic antitussive medicines of central action is shown mainly with a cough that is associated with marked irritation of mucous epiglotti (upper) respiratory tracts arising from infectious and / or catarrhal inflammation. In this case, the positive result is usually enhanced when they are used together with preparations of peripheral antitussive action with enveloping effect. An example of such a combined action is Broncholitin. But the effectiveness of its use is justified only in the absence of pronounced inflammatory changes in the mucosa in the lower parts of the bronchopulmonary system, in connection with the fact that the ephedrine entering into it "dries" the bronchial mucosa, increasing the viscosity of the bronchial secretion, increasing the inefficiency of coughing in bronchitis and pneumonia. Ephedrine also has an exciting effect on the central nervous system, so the use of this drug in children unjustified and dangerous - it can disrupt the child's sleep, contributing to increased dyspnoea and unproductive cough.
It is important to remember that the use of this group of drugs as self-medication can do more harm than good, cause complications in the form of bronchial obstruction, increasing the viscosity of bronchial secretions and promote the progression of inflammatory processes, edema and lowering of the pathological process in lower departments.
Group of peripheral drugs
The peripheral group includes pharmacological preparations from dry cough acting on nerve receptors and endings that are located in the tracheobronchial tree - Libexin, Levopront and Helicidin.
Libexin
Libexin is considered an effective antitussive drug, which additionally has a local anesthetic, bronchodilator and spasmolytic effects and has a moderate expectorant and anti-inflammatory effect with minimal decrease in respiratory activity center. The basic form of Libexin is round flat tablets of almost white color with a dividing stripe into four equal parts on one side and engraving "LIBEXIN" on the other, containing 100 mg of active ingredient - prenoxdiazin hydrochloride.
This drug is currently considered the drug of choice in the treatment of laryngitis, tracheitis, pharyngitis and less frequent bronchitis, which are accompanied by a dry, unproductive cough. Also as one of the components in the complex therapy of pleurisy and pneumonia, which are accompanied by pain and obstructive syndromes, and with congenital diseases of bronchopulmonary system, cystic fibrosis and other chronic lung diseases: tuberculosis, pneumoconiosis, emphysema in children and adults as a symptomatic remedy with compulsive irritating coughing.
With caution this drug is prescribed for ulcerative lesions of the gastrointestinal tract, as well as in the presence of a history of gastric bleeding, liver or kidney failure, glomerulonephritis, cystitis, allergic form of bronchial asthma with a tendency to stand bronchial obstruction.
Libexin is contraindicated for individual intolerance, pregnancy (especially in the first trimester), lactation and in early childhood.
Levoprint
This drug is prescribed for frequent dry cough to children and adults. It is released as a syrup and drops for oral administration.
Absolute contraindications to its reception are:
- pregnancy in any period;
- lactation period;
- liver failure;
- decreased mucociliary function of the bronchi;
- hypersensitivity to the components of the drug.
Levoproton can cause side effects in the form of increased fatigue, diarrhea, drowsiness, dizziness, tachycardia, heartburn, nausea, vomiting and allergic reactions. With long-term use of this drug, mental disorders, the development of sopor and coma, possible, especially with overdoses in childhood and the elderly.
Group of antitussive drugs combined action
These drugs have simultaneously reducing the cough reflex effect and expectorant, moderate anti-inflammatory and mild bronchodilator actions in connection with their constituent several components - Stopptussin, Butamirate, Libexin-Muko, Tussin plus, Bronholitin, Protiazin, Hexapneumine.
All drugs of this group are widely used for the treatment of dry and unproductive cough, but it is important to remember that
They are contraindicated in the presence of productive wet cough or other conditions that are accompanied by abundant sputum discharge, as well as with the likelihood of developing pulmonary hemorrhages.
Therefore, the choice of an antitussive drug should be performed by a physician on the basis of an anamnesis, clinical examination of the patient and, if necessary, additional methods (laboratory or instrumental).
Indications and features of antitussive drugs
A group of "true" antitussive drugs of central and peripheral action is shown mainly with a cough that is associated with marked irritation of mucous epiglotti (upper) respiratory tracts arising from infectious and / or catarrhal inflammation. In this case, a positive result is usually enhanced when they are used together with drugs that have anti-inflammatory and enveloping effects in addition. An example of such a combined action is Broncholitin. But the effectiveness of its use is justified only in the absence of pronounced inflammatory changes in the mucosa in the lower parts of the bronchopulmonary system, in connection with the fact that the ephedrine entering into it "dries" the bronchial mucosa, increasing the viscosity of the bronchial secretion, increasing the inefficiency of coughing in bronchitis and pneumonia. Ephedrine also has an exciting effect on the central nervous system, so the use of this drug in children unjustified and dangerous - it can disrupt the child's sleep, contributing to increased dyspnoea and unproductive cough.
It is important to remember that the use of this group of drugs as self-medication can do more harm than good, cause complications in the form of bronchial obstruction, increase the viscosity of the bronchial secretion and promote the progression of inflammatory processes, edema and lowering of the pathological process in the lower parts of the bronchopulmonary system.
Cough preparations of local action
This group of antitussive drugs includes drugs that depress the cough reflex as a result of anesthesia of the mucous membranes respiratory tract, in connection with which the irritating effect of various agents, both infectious and non-infectious (chemical and physical factors). These drugs also reduce the viscosity of phlegm and relax the bronchi.
To local anesthetics include tablets Libexin, Tusuprex and resorption tablets Falimint.
Tusuprex
Tablets Tusuprex is often used for symptomatic cough therapy in children from the year, adolescents and adults patients, but in pediatric practice they are used only according to the doctor's prescription (due to the complexity of dosing in young children age). Also, this drug should not be used against the background of the development of bronchospasm (with obstructive bronchitis and bronchial asthma), in the presence of confirmed bronchiectasis and for any disease that is accompanied by a difficult separation phlegm.
Falimint
Tablets for resorption of the Falimint are indicated in the presence of an unproductive irritant cough that is caused by pronounced catarrh of the upper respiratory tract (pharynx, larynx and upper parts trachea). This drug has in its composition a local anesthetic component and therefore reduces the intensity of dry cough.Falimint does not apply:
- in children under 4 years;
- during pregnancy and lactation;
- hypersensitivity to the components of the drug;
- with intolerance to fructose.
Drugs affecting the state of bronchial secretions
Separately, a group of drugs with mucolytic and / or expectorant action is distinguished. These tablets and syrups, which are used in wet productive cough and are divided into the following subspecies of drugs:
1. Expectorants:
a) having predominantly reflex action:
- Terpinhydrate, Thermopsis, Sodium benzoate, Lycorin;
- the roots of Licorice, Devyasil, Istad and Althea;
- essential oils.
b) stimulating gastropulmonary and / or vomiting reflex:
- Gwaiphenazine, Ipecacuan, Sodium Citrate, Ammonium Chloride.
c) resorptive action with increased bronchial secretion:
- Sodium iodide, Sodium bicarbonate, Ammonium chloride, Potassium iodide.
2. Mucolytic agents:
a) direct action, which quickly destroy the polymer bonds of bronchial mucus:
- Mukaltin;
- The mukonist;
- Mukobene;
- Exomuk;
- Acetylcysteine, Fluimutsil, Carbocysteine group (Mukopron, Bronkatar, Mukodin, Fluvik, Mistabron, Mucosol;
- preparations with infusions of leaves of plantain, mother-and-stepmother, licorice;
- enzymatic preparations that reduce the viscosity of sputum - Chymotrypsin, DNAase, Trypsin, Ribonuclease, Streptokinase, DNAase, Pulmozyme;
b) Indirect action (mucoregulators):
- Ambroxol (Ambrobene, Ambrosan, Ambroghexal, Khalixol, Medovent, Lazolvan, Ambrollanazolvan);
- Bromhexine (Fulpen, Flegamine, Broxin, Bisolvon);
- Carboxymethylcysteine, Sobregorod, Sodium Ethanesulfate, Letostein, Sodium bicarbonate;
- changing the productivity of bronchial glands - anticholinergic and antihistamines.
3. Anti-inflammatory drugs with bronchodilator and / or expectorant effect:
- Suprima-bronho, Sinupret, Pulmotin, Glytsiram, Ascoril, Gelomirtol, Gedelix, Evkabal and Prospan.
Features of the use of expectorant drugs
At the basis of the mechanism of action of expectorants are - increased secretion of sputum by bronchial glands, dilution of secretion by reflex by way of and as a result of this easier departure of mucous or mucopurulent sputum from the lower parts of the bronchopulmonary system to its higher departments. These drugs actively irritate the receptors of the mucous membranes of the stomach and, inducing vomiting center, which is localized in the medulla oblongata and, in connection with this, significantly increase sputum excretion bronchi.
Expectorants are prescribed for diseases that are accompanied by a decrease in sputum production or vice versa, an abundance of thick, viscous, difficult-to-separate mucus that accumulates in the bronchi (with bronchitis and bronchial asthma), larynx (with laryngitis), in the trachea (with tracheitis), in the alveoli and small bronchioles (with bronchopneumonia and cystic fibrosis).
The use of expectorants for the treatment of respiratory diseases can not be combined with antitussive drugs of central and peripheral action that oppress the cough center or inhibit cough reflex. In this case, a large number of sputum accumulates in the lower respiratory tract, which often leads to their obliteration and development of severe infectious and inflammatory diseases (obstructive bronchitis, bronchopneumonia, pleurisy).
There are two groups of expectorant drugs that differ in the mechanism of their therapeutic action:
- means of reflex action;
- medicines with direct effect.
And
- preparations of vegetable origin;
- synthetic drugs.
Popular expectorants of plant origin
Basically, almost all expectorants with a reflex action mechanism are represented medicinal plants and their extracts, which intensify and accelerate the excretion of sputum from the organs bronchopulmonary system. This group of medicines is extensive and in most cases they are represented by herbal medicines.Expectorants have medicinal plants:
- licorice;
- thermopsis;
- anise;
- marshmallows;
- plantain;
- elecampane;
- ledum;
- oregano;
- thyme;
- mother and stepmother;
- ipecacuanha;
- thyme;
- violet;
- pine buds, etc.
Herbal extracts of these herbs are included in various breast pills, tablets, powders and syrups for the treatment of moist productive cough in children and adults.
Pills for cough with thermopsis
In most cases (and this is actually so), this drug is considered to be the best drug for treating wet cough.
Tablets from cough with thermopsis and sodium bicarbonate are very popular earlier and effective at the present time. Their balanced composition is a herb of thermopsis, which enhances sputum secretion while simultaneously reducing its viscosity and sodium bicarbonate, an emollient and gently tearing bonds in sputum molecules - effectively dilute sputum, promoting its rapid evacuation from the upper and lower divisions of the respiratory tract.
In these tablets there are no artificial additives, synthetic components, and in comparison with expensive medicinal preparations in efficiency they do not concede.
But for the purpose of this drug there are absolute contraindications:
- individual intolerance to the components of the drug;
- erosive and ulcerative pathological processes of the stomach and other parts of the digestive system;
- pregnancy.
Thermopsis is today considered to be an excellent remedy for treating wet cough in children. But it is important to remember that it is not used for infants for the therapy of bronchitis or bronchopneumonia with a large amount of sputum, while the child can not effectively cough, and thermopsis additionally activates the increase in mucus secretion by bronchial glands, which quickly leads to the development of respiratory insufficiency. Also, the herb of thermopsis has an emetic effect and the babies show frequent regurgitation and vomiting, which leads to dysfunctions of the digestive system, the development of lethargy, reduced weight gain and overall weakening of the body the kid.
Also, if the dose of Thermopsis is exceeded, its emetic effect is manifested, which can cause nausea at the beginning of treatment at any age (especially in children).
Mukaltin
Another effective herbal preparation for the treatment of wet cough is Muciltin tablets from cough, which are created on the basis of the extract of the drug althea. It has a pronounced anti-inflammatory and expectorant effect, which is due to reflex stimulation ciliary epithelium of the respiratory tract and an increase in peristalsis of the bronchi and bronchioles with activation of secretion bronchial glands.
Muciltine tablets also contain sodium bicarbonate.
Currently, this drug is recognized as one of the most effective expectorant drugs that are used to treat productive wet cough in children and adults.
Doctor Mom
Dr. Mom is a complex herbal preparation that is used in the treatment of diseases accompanied by a damp productive or cough with viscous sputum. It consists of active plant substances that have expectorant, softening, secretory, anti-inflammatory, moderate bronchodilator and mucolytic effects.
At the heart of pastilles and syrup are dry extracts from leaves, roots, seeds, bark, flowers of medicinal plants: aloe, elecampane, basil, ginger, licorice, turmeric, pepper cubebe, terminalee beleriki and nightshade Indian.
Additional positive characteristics of this drug is its good tolerability, even with prolonged use.
With caution, this medicine should be taken by pregnant women and with lactation and only with the appointment of a doctor and with constant monitoring.
Also, Dr. Mom is not assigned simultaneously with medications that suppress the cough reflex. A good effect is the use of this plant expectorant in combination with mucolytic drugs (Ambroxol, Lazolvan and Bromhexin).
At the beginning of treatment or with prolonged or uncontrolled use of the drug, nausea may occur before vomiting or frequent regurgitation in young children, which is due to the presence in the formulation of an extract of licorice, which has a weak emetic effect.
Expectorants of artificial origin
At the basis of the mechanism of action of expectorant antitussive drugs of direct action is the enhancement elimination of bronchial secretion as a result of exposure to sputum and stimulation of bronchial peristalsis. This group of medicines is represented by artificial medicinal preparations - iodized salts of potassium and sodium, Benzoate sodium, sodium hydrochloride, terpinhydrate, ammonium chloride, potassium bromide and essential oils - eucalyptus fir, aniseed. They are quite effective and are mainly used for inhalations.
In the pharmacy network, you can buy a combination of drugs for the treatment of wet cough, which have in their composition as plant substances, and artificial components - Moist-anise drops and Pertussin, which contains the extract of thyme and bromide potassium.
Mucolytic drugs
The action of mucolytic drugs is aimed at diluting the thick and viscous secretion bronchial glands without increasing sputum secretion to facilitate their evacuation from the lower and upper respiratory tract.
Mucolytic tablets today are considered one of the main components in the therapy of wet cough. They also restore the mucous membranes of the bronchi and the elasticity of the lungs.
To this group of drugs are - Ambroxol, ATSTS, Bromheksin, Carboccithin. When combined with various plant expectorants with mucolytics, the effectiveness of both increases sharply. Also mucolytics potentiate the action of antibacterial drugs, increasing their effectiveness, Therefore, they are widely used in complex therapy of pneumonia, bronchiolitis, obstructive bronchitis and pleurisy.
Ambroxol and Bromhexin activate the formation of pulmonary surfactant, which ensures the normal functioning of the alveoli of the lungs, preventing their collapse and adhesion, therefore they are widely used in pediatric practice for the treatment of bronchopulmonary pathology in young children, premature babies and toddlers with intrauterine hypotrophy.
Their negative side is the ability to cause bronchospasm, which is considered a contraindication to the use of these drugs during periods of exacerbation of bronchial asthma.
The main groups of mucolytic drugs
In medicine and pharmacology mucolytics are divided into several groups:
1) drugs that are developed based on proteolytic enzymes - chymotrypsin, trypsin and mesna. But this group of medicines is used only in extreme cases, always in a hospital and under the supervision of the attending physician;
2) drugs based on acetylcysteine - ATSTS, Mukobene, Fluimutsil, Exemuk, Mukomist and others.
The mechanism of action of these drugs is based on dilution of thick and viscous sputum as a result of rupture of large molecules of mucus to small in connection with this facilitates the process of coughing and evacuation of sputum from the respiratory tract. Also, acetylcysteine drugs have a protective effect on the inflamed cells of the bronchopulmonary system.
Preparations of this group can not be taken simultaneously with antitussive drugs, which leads to stagnation of sputum in the bronchi and alveoli, oppression of the cough and the development of complications (bronchopneumonia, respiratory failure, and with the layering of aggressive microflora - abscesses of the lungs and purulent pleurisy).
3) drugs based on carbocisteine (mucoregulators) - Bronkatar, Carbocysteine, Drill, Mukodin, Fluvik, Mukoprint.
They normalize not only the qualitative composition of the sputum (liquefying it and easing the cough), but also increase the activity of cells that produce bronchial secretion and the work of cilia of bronchial epithelium and bronchioles. And also have an anti-inflammatory effect and stimulate local immunity in connection with the increase in the production of protective immune complexes (group A immunoglobulins).
The most modern preparations of this group are Fluviert, its distinctive feature is a longer lasting effect.
4) mucolytics with expectorant effect - derivatives of Ambroxol and Bromhexine
The mechanism of action of these drugs is based on stimulation of secretion by alveoli of liquid sputum and liquefaction and already accumulated mucus, stimulate the formation of immunoglobulin and lysozyme in a bronchial secretion and have an expectorant effect.
But the pronounced effect of these drugs does not come immediately, but only on the fourth - the sixth day from the beginning of treatment.
Bromhexine preparations include - Flexin, Bronchosan, Flegamin, Bromoxin, Fulpen, Solvin.
Drugs of this group also can not be used simultaneously with antitussive drugs in connection with possible accumulation of excess sputum as a result of cough suppression and the absence of evacuation of the accumulated secretion from the bronchi and alveoli. In addition, when this group of drugs is prescribed, the use of a vibratory (drainage) massage and postural drainage (the patient's acceptance of certain body positions that improve the outflow phlegm).
Ambroxol preparations are active metabolites of Bromhexine with an improved chemical structure, so these medicinal means have a complex effect on the respiratory tract - mucolytic, anti-inflammatory and expectorant. Since 2012 Ambroxol is on the list of the most important and vital medicines. But Ambroxol preparations also can not be taken simultaneously with antitussive drugs.
The main drugs are Ambrobene, Lazolvan, Ambrohexal, Khaliksol, Bronhoverne, Dephlegmine, Ambrolan.
Good tablets against coughing
Definitions of "good pills for cough" from both medical and pharmaceutical point of view does not exist. Cough is only a symptom, the complete elimination of which or even its reduction can do more harm than good. With the development of bronchopulmonary pathology in both children and adults, treatment is aimed at eliminating the cause of the pathological process - cupping bronchospasm, the elimination of inflammation, the removal of a foreign body from the trachea and bronchi or the treatment of other systems and organs - neuroses, psychopathies (with neurotic character of coughing).
Therefore, the choice of the drug for cough treatment is individual and is made after a patient's examination, careful collection of anamnesis and diagnosis.
Tablets for children cough
The right choice of medicines for cough therapy in children is determined by the main factors - the cause of cough, the mechanism of action of antitussive drugs, features of a cough reflex in a child, and the full spectrum of all these factors can be assessed only by a specialist who will assign the baby the correct one in each case treatment.
Inhibition of cough reflex in a child, the use of several antitussive drugs from different groups simultaneously, increasing dosages, multiplicities and the duration of taking the drug can lead to many negative consequences, the development and progression of hazardous to health and even life complications.
Tablets for coughing during pregnancy
Pregnancy in most cases is an absolute contraindication to taking many antitussive medicines, especially narcotic antitussives, many complex medicines, in connection with their pronounced negative impact on the embryo, followed by the development of fetopathies and other violations of the correct laying of organs and systems of the future child.
Relatively contraindicated medicinal products for treating cough are:
- insufficiently studied drugs, in which application the risk of a dangerous effect on the baby's body is possible;
- medicines, with the possible risk of development in the future mother of side effects.
Also on any period of pregnancy, some medicinal plants and medicinal funds that have them in its composition - juniper, nettle, oregano, mother-and-stepmother, St. John's Wort and others. The negative effect of medicinal herbs on the fetus is sometimes many times more active than synthetic drugs - they have a fetopathological and teratogenic effect on the fetus, change the hormonal background of the pregnant, can stimulate the contraction of the myometrium and cause miscarriages, especially in the early terms.
Therefore, even at the planning stage, and even more so in the early stages of pregnancy, it is necessary to take with caution any medicinal and / or homeopathic medicines and herbs.
kashelb.com
Pills for cough
To successfully get rid of cough, first of all, you should determine the type of cough and only after that go to the choice of a drug that helps to overcome, rather than aggravate the ailment.
Most of the cough medicines are dispensed without a prescription, however, it must be remembered that the path to recovery begins with the establishment of a correct diagnosis. Tablets from a cough, shown with one type of cough, are capable of harming in another course of the disease. That's why pay attention to your condition.
For exhausting attacks with a sore throat, not giving a night's sleep, you can recognize a dry cough. In medical circles, this type of cough is called unproductive, characterized by a lack of sputum, as well as pain in the muscles of the abdomen and chest. The cause of this cough is irritation of pharyngeal cough receptors. Cope with the problem in this situation will help antitussives, stopping the attack.
The productive type of cough is accompanied by the separation of the separated. Sputum preparations from bronchial tubes, trachea and lungs are facilitated by expectorants (increase production of detachable drugs) or mucolytics (dilute sputum). Some pills for cough by stimulating special cilia help to clear the airways.
Use of drugs containing codeine (narcotic substance) is possible in the most severe cases. Preference should be given to codeine in its pure form or its analogue dextromethorphan. With regard to combined drugs, they have an expectorant effect. As a result, on the one hand, such drugs facilitate the release of sputum, and on the other - consist of components designed to suppress cough, preventing the separation of the separated. The latter is unacceptable in the productive form of cough.
Indications for use of tablets against cough
The cause of coughing is not always respiratory diseases. Cough often accompanies infectious diseases of a viral or bacterial current, which include: laryngitis, sinusitis, tonsillitis, pharyngitis, pneumonia, bronchitis, tuberculosis, etc. The cause of coughing can be childhood diseases, for example, whooping cough, as well as allergic state. Coughing attacks characterize the pathological processes of the organic type of the brain, manifest themselves on the nervous soil, with cardiac disorders (heart disease, angina pectoris, etc.), with the defeat of the respiratory tract by aggressive environments. This list can be continued indefinitely. Therefore, it is important to establish and eliminate the root cause of the disease, and not solve the problem of coughing in any fastest way.
The choice of a cough pill depends on the nature of the cough. In conditions accompanied by a dry, excruciating cough, the means that depress the center of cough in the brain are shown:
- Combination preparations with the active ingredient codeine - "kodelak "terpinkod N "tercodin
- pastilles based on dextromethorphan - "alex plus
- substances with butamirate - "sinecode "omnitus "panatus".
Tablets "libexin" with the active substance prenoxdiazine soothe the cough receptors of the throat, keeping the respiratory functions and not causing pharmacological dependence. The drug is equal to codeine by the strength of the drug effect. Cough seizures are also a means for resorption based on menthol and eucalyptus ("pectusin"), as well as preparations from licorice - "glycyram"
With viscous, poorly draining and sparse sputum are effective:
- mucolytic agents based on bromhexine - "bromhexine "ascoril "solvin
- preparations with ambroxol - "ambroxol "kodelak bronho "ambroben "flavamed
- expectorating mucolytics of acetylcysteine - "ACTS "fluimutsil "acetestin".
Indications for the use of tablets against cough with the active ingredient acetylcysteine concern cases where it is necessary to increase the amount of detachable.
An expectorant effect is also achieved by the use of phytopreparations - "mukaltin "lycorin "pectussin "thermopsis".
In addition to the correct selection of medicines, it is important to ensure sufficient humidity in the room and drink more liquid (up to 6-8 glasses per day).
Form of issue
All pills for cough can be divided into the following groups:
- drugs that suppress the center cough in the brain and affect the nerve endings of the receptors;
- agents affecting smooth muscle structures and bronchial mucosa;
- drugs that have a direct effect on bronchial secretion (sputum).
From the above, you can make an unambiguous conclusion that the treatment is selected individually for each case. An important form is also the form of the release of the product. Effervescent tablets and for resorption are characterized by a high rate of action and digestibility, but are unlikely to be suitable for babies. Very small patients are recommended sweet antitussive syrups. People suffering from peptic ulcer, hyperacid gastritis or having an increased acidity of gastric juice will be countered with effervescent antitussives.
The type and dosage of the drug is prescribed by the physician based on the symptoms, age and individual characteristics of the patient's body. For any pharmacological agent, regardless of the form of release, there are contraindications and side effects. For example, a popular drug for wet cough - thermopsis, consisting entirely of natural ingredients, is prohibited in the treatment of bronchitis and pneumonia in infants. Babies are not able to cough up a large amount of waste mucus, which in some cases provokes respiratory failure. In children under 5 years of age, a drug with an overdose provokes a vomiting reflex, is contraindicated in pregnant women and people suffering from peptic ulcer and 12-gut.
Therefore, before starting treatment, you should establish the correct diagnosis and get recommendations for taking antitussive medications from a specialist.
Pharmacodynamics of tablets against cough
To date, there is no universal cough pill, due to the fact that the therapeutic effect on dry and wet type of cough is fundamentally different. In the presence of dry cough, it is not advisable to use tablets for wet cough with a stopping effect, which will cause blockage of bronchial lumens with departing phlegm. Medicinal substances from the productive (wet) cough, which help to reduce the viscosity and easily withdraw phlegm, are useless in case of a dry cough caused by trachea inflammation, irritation of bronchial mucosa, influence aggressive environments.
Actively acting on the cough center, drugs are divided according to the principle of impact on: central, peripheral and combined effects. Pharmacodynamics of tablets against cough (the mechanism of action on the human body) is characterized by the properties of the constituent components. For example, drugs with narcotic substance codeine are effective enough for a dry, debilitating cough without sputum discharge. However, these medicines are released strictly by prescription, as they are addictive. Modern pharmacology has no less effective, safe, non-narcotic drugs that do not affect the respiratory center. To such accessible antitussive tablets carry - "либексин "тусупрекс" and others. They most often lower the receptor sensitivity of the bronchial mucosa (peripheral effect), but also can block the cough reflex. From this group of drugs there is no addiction, so they are used for cough therapy in children.
Multicomponent tablets for cough are effective for any course of the disease, excluding wet cough. Coughing in this case can disrupt the purifying capacity of the lungs, the withdrawal of mucus and lead to the development of pneumonia, problems with ventilation. Combined funds have the most impressive list of side effects and contraindications. It is also difficult to select the right dosage and the lack of the ability to combine them with other drugs.
When it comes to a damp cough, most often remember the popular tablets for coughing "thermopsis". And here the patient needs to be as attentive as possible. The fact is that the familiar and inexpensive means of "thermopsis" is now available in two formulations:
- does not contain chemistry, includes only the herb of lanceolate and sodium hydrogencarbonate (possible therapy for children);
- consists of codeine (narcotic substance), herbs of thermopsis, sodium bicarbonate and licorice root.
Consider the pharmacodynamics of this drug:
- codeine - is characterized by a minor sedative, analgesic effect, blocks the cough reflex without inhibition of the respiratory center and functions of the ciliated epithelium, does not reduce the amount of secretion in the bronchi;
- thermopsis grass (with active ingredients - isoquinoline alkaloids) - activates the respiratory and vomiting centers. It has a distinct expectorant effect, promotes activation of secretory function of bronchial glands, stimulation of ciliary epithelium and acceleration of mucus excretion;
- sodium hydrogen carbonate - causes the pH-shift of the bronchial mucus towards the alkaline medium and reduces the viscosity of sputum. Stimulates the work of ciliated epithelium and bronchioles;
- root of licorice - provides an easy divergence of secret due to the content of glycyrrhizin. Has anti-inflammatory and antispasmodic effect.
Pharmacokinetics of tablets against cough
By pharmacokinetics is understood the biochemical transformation of drug molecules in the human body. The main pharmacokinetic processes include - suction, excretory (excretory), distribution and metabolic properties.
Absorption of the tablet from cough occurs after dissolution, usually in the small intestine. Further, the molecules of the drug enter the systemic circulation. Absorption has two characteristics - the speed and degree of absorption (decreases when a pharmacological substance is used after a meal).
The distribution of the drug occurs in the blood, intercellular fluid and tissue cells.
The allocation of drugs is carried out in an unchanged form or as substances of biochemical transformation - metabolites that have higher polarity and solubility in the aqueous medium in comparison with the initial substance, which causes a simple elimination from urine.
Excretion (excretion) of the drug is possible through the urinary, digestive system, as well as through sweat, saliva and with exhaled air. The excretory function is influenced by the rate of receipt of the drug with the blood flow to the excretory organ and the characteristics of its own excretory systems. The most common way - the kidneys, bronchial glands and mucous respiratory system.
The pharmacokinetics of tablets from cough is based on the main active ingredient that is part of the drug:
- codeine - is characterized by a high rate of absorption, blocks the cough after half an hour after ingestion, provides a persistent antitussive and analgesic effect up to six hours. It is transformed in the liver, the half-life begins in 2-4 hours;
- glaucine hydrochloride - is well absorbed by the digestive system, transformation occurs in the liver, excretion by the kidneys (metabolites of the primary species);
- ambroksol - is maximally absorbed, excreted in urine;
- bromhexine - absorption reaches 99% in half an hour after use. In plasma it forms a bond with proteins. It is characterized by penetration through the placenta, accumulation in the liver, kidneys, fat and muscle tissue. Half-life occurs an hour and a half later;
- carbocisteine - is actively absorbed and metabolized during the primary passage through the liver. The maximum concentration is observed two hours after oral administration. Excretion is carried out with urine practically unchanged;
- acetylcysteine - has a low bioavailability (no more than 10%), which is explained by the formation of cysteine during the primary passage through the liver. Peak concentrations - after 1-3 hours. Characterized by penetration through the placental barrier. For excretion, the kidneys respond, a small part of the substance in the unchanged form excretes the intestine.
Use of cough tablets during pregnancy
A pregnant woman before taking a pill from a cough should carefully study the instructions and consult a doctor. The specialist determines the cause of the cough, and prescribes the appropriate treatment. Coughing attacks not only infections of the upper or lower respiratory tract, but also allergic, neurotic reactions, stomach or diaphragm problems, thyroid disorders, cardiovascular system disorders etc.
The greatest danger is a dry, painful cough. Such seizures can increase intra-abdominal and blood pressure in a future mother, which can trigger the mechanism of premature resolution of pregnancy, placental abruption and even cause interruption pregnancy.
Most of the pharmacological drugs are prohibited for admission during the waiting period of the baby. However, the use of tablets against cough during pregnancy on the basis of plant components such as:
- "Mukaltin containing the grass of the althea. Take under strict supervision of the doctor three to four times a day, before eating. The duration of therapy is one to two weeks;
- sucking pills-candies based on eucalyptus (better without sugar) - the inclusion of the herbal mixture in them, usually, minimally. The positive effect is achieved due to the abundant production of saliva, which moisturizes and softens the pharyngeal region and larynx, where desires for cough arise;
- drugs with active substance dextromethorphan (suppresses the cough center) is prescribed for severe attacks, when it is impossible to eliminate the problem in another way;
- bromhexine in many expectorants is also often used to treat pregnant women;
- "Bronchitis" is a German medicine made from plant components. It is indicated for any type of cough (on a tablet three times a day, after a meal). The duration of the course is from seven to ten days;
- "Ambroxol" - dilutes thick viscous mucus, facilitates expectoration. Allow for the treatment of pregnant women under supervision of a specialist in the second / third trimesters;
- "Kodelak" - is not desirable during gestation, since codeine is a drug that can cause dysfunction in embryonic development, often generates heart disease. Assign only in emergency cases, when other means are powerless.
In any case, one should not engage in self-medication during pregnancy, even with traditional medicine. Oddly enough, even plant raw materials can harm with individual intolerance. The choice of the method of treatment, the dosage of the drug and the duration of the therapeutic effect are prescribed by the doctor strictly individually.
Contraindications to the use of tablets against coughing
Each medication has indications, contraindications and a list of side effects. Tablets for cough are selected on an individual basis for each patient. Particular care should be taken when treating cough in young children, pregnant and lactating women.
Combined antitussive drugs are not prescribed in cases of individual intolerance, during pregnancy and lactation, children under two years of age, as well as with the detection of respiratory insufficiency of the second / third degree and the presence of severe bronchial asthma.
The use of expectorant tablets is inadmissible in parallel with the intake of substances that depress the cough center and inhibit the cough reflex. This combination provokes severe inflammatory diseases of the lower parts of the respiratory system (for example, pneumonia).
Contraindications to the use of tablets from cough "thermopsis" apply to infants with bronchitis or inflammation of the lungs, because with abundant sputum, they can not clear their throats, which will cause a respiratory failure. Known tablets at high dosages cause nausea in children at the beginning of the course.
Mucolytics "bromhexine "ACTS "ambroxol" is not recommended during the exacerbation of bronchial asthma due to the threat of bronchospasm. "Bromhexine" is contraindicated in the first three months of gestation, to children under three years old, with the presence of a stomach ulcer, recent bleeding and individual intolerance. Tablets "ACTS" can be administered after the tenth day of life, but they are not used for pulmonary hemorrhage, stomach ulcer, hepatitis, in cases of renal insufficiency and intolerance to fructose. The drug is not combined with tetracycline, a semisynthetic group of penicillins, aminoglycosides, cephalosporins, as well as with other antitussive drugs in order to avoid stagnation in respiratory ways.
Effervescent or absorbable tablets from cough are famous for their speed of digestion and efficiency, however they are not suitable for therapy of patients with high acidity, gastritis and peptic ulcer stomach.
When choosing a cough remedy, follow the instructions, but it's best to visit a literate specialist who will determine the cause of the painful condition and write the most effective means.
Side effects of tablets against cough
Tablets from cough have their list of side effects - from nausea to drug dependence.
The drug "libexin" requires admission strictly according to the prescribed schedule (four times per day in accordance with the patient's age), without chewing to avoid anesthetizing the oral mucosa. A popular medicine "stoptussin" can cause diarrhea, headache, pain in the abdomen, dyspepsia, allergic reaction and dizziness. When taking "tusupreksa used in the treatment of dry, unproductive cough, in some patients there is a digestive disorder.
Side effects of tablets from the cough of the mucolytic group ("bromgexin "ACTS etc.) include the onset of bronchospasm, which is especially dangerous in the period of exacerbation of bronchial asthma. Such patients should prefer broncholytics without atropine. Admission of the drug "ACTS" in addition to the above is fraught with skin reactions, elevation of blood pressure, dyspepsia.
Tablets from a cough based on thermopsis are also capable of provoking an allergic effect (itching, rash on the skin, etc.) and cause nausea.
Medicinal substances from cough of narcotic content (for example, with codeine) cause pharmacological dependence, allergy. In case of an overdose, constipation, vomiting, delay in urine release, problems with coordination of eyeballs movement, weakness, respiratory center depression are observed.
If coughing attacks increase, and there is no opportunity to visit the doctor, then carefully study the instructions for the drug being purchased for contraindications and side effects.
Dosing and Administration
The specificity of taking antitussive drugs depends on the nature of the disease, the age of the patient, the individual characteristics organism, the presence of chronic diseases, the presence of addictions (for example, smoking), body weight and a number of other factors.
To establish the correct diagnosis, a specialist should appoint a proper treatment. The method of application and dose is also determined by the doctor individually.
Tablets for coughing "Libexin" or "Libexin muko" (with mucolytic carbocysteine, reducing the viscosity of phlegm) are used without chewing up to 4 times a day. Dosage depends on the patient's age and varies from the fourth part of the tablet to two tablets per one-time intake. The duration of the effect is up to four hours.
Tablets from cough "stoptussin" drink up to 6 times a day, since the period of partial elimination is six hours. The medicine for resorption "falimint which helps with an unproductive irritant cough, is allowed to apply up to 10 times a day, provided the duration of therapy is not more than several days.
Mucolytic preparations based on plant raw materials should be consumed before meals. The recommended dose of "mukultina" for adults is 1-2 tablets up to 4 times a day, for children - from half a tablet to two tablets for a one-time appointment. "Thermopsis" without codeine is attributed to the tablet three times a day for up to five days. The maximum daily dosage of the drug is 0.3 g or 42 tablets. Children who have reached the age of 12 are allowed on a pill 2-3 times a day. The appointment of "bromhexine" to adults and children from 10 years is 8 mg three to four times a day. Children under two take this drug 2 mg three times a day. The treatment course can be up to four weeks.
Effervescent tablets from the cough "ATSTS" drink after eating, pre-dissolving the medicine in half a glass of water, juice or cold tea. The daily norm of the drug depends on the body weight: patients with a weight of more than 30 kg. use up to 800mg. facilities. Children dosage is selected based on age: up to 2 years - 50 mg. 2-3 times / day, from 2 to 5 years - 400 mg. in four receptions, from 6 years - 600 mg. for three sessions. Duration of treatment varies from three to six months, which is affected by the complexity of the pathological condition.
Overdose
The reaction of the body to taking a pill from a cough can be completely different. In some cases, patients are concerned about nausea due to individual intolerance to the components of the drug. An overdose of an antitussive drug can provoke an allergic reaction in the form of itching, rashes on the skin.
Symptoms of acute or chronic overdose from narcotic tablets (eg, codeine-containing):
- blurred vision;
- sticky, cold sweat;
- weakness, drowsiness;
- change in blood pressure;
- a nervous state;
- fast fatiguability;
- bradycardia;
- unreasonable anxiety;
- convulsive condition;
- respiratory problems;
- pain in the chest;
- miosis;
- stopping breathing;
- coma;
- loss of consciousness;
- the emergence of pharmacological dependence;
- loss / weight gain.
In the most severe cases, gastric lavage, restoration of respiratory system functions, normalization of pressure and work of the heart, the introduction of special substances into the vein, such as naloxone (opiod analgesic).
Interactions of tablets against cough with other drugs
Combined pills for cough with mucolytic effect "codeterpin" increase the effect of hypnotics, sedatives and analgesics. This must be taken into account before the reception of persons driving a vehicle and engaging in other activities requiring increased attention.
Antitussive drug "ACTS" is forbidden to admit with tetracycline group, semisynthetic preparations of penicillin, aminoglycosides and cephalosporins. Do not combine "ACTS" with other tablets from coughing to prevent stasis of the airways.
"Libexin" should not be combined with mucolytics, expectorants, since sputum excretion can be difficult.
With respect to the interaction of tablets against cough with other drugs that cough the cough reflex, both codeine, it can be unequivocally said that the latter complicate the coughing up of diluted sputum and its accumulation in lungs.
A number of pharmacological agents strengthen each other's action. This effect is observed with simultaneous reception of "glycodine" with narcotic antitussive agents. In this case, "glycodine" often interacts with monoamine oxidase inhibitors.
Before you start taking any cough medicine, carefully study the instruction leaflet and do not forget to notify the attending physician of the medications you take.
Conditions for storing tablets against coughing
The main conditions for the storage of tablets against cough include the following points:
- The storage location must be dry, closed to light penetration and inaccessible to children;
- the acceptable temperature is usually 15-25 ° C, unless there are specific instructions in the manual;
- place medicines away from heating / heating appliances.
Do not carefully trim the empty part of the blister to maintain the aesthetic appearance of the packaging. After a while it will be difficult or absolutely impossible to determine what helped this "white" tabletochka. Moreover, you can take the wrong medicine. The same goes for fans to shift tablets into containers from other drugs.
If the coughts, sealed in a paper blister, get wet - discard them immediately. It is unlikely that such a package will preserve the medicinal properties of the drug from the effects of the aquatic environment.
Visual discoloration of the tablet, layering, etc. is a reason for its urgent disposal.
Get a useful rule for yourself - every six months to conduct an audit in the medicine cabinet, replenish it with the most necessary medications, including antitussives. It is also expedient to store pharmacological preparations in groups according to the intended use.
Shelf life
Remember that the expiration date on the package applies only to sealed preparations. Do not store or use expired medications, no matter how "normal" they may seem.
Shelf life on tablets from cough may vary from 3 to 5 years.
ilive.com.ua
Best candies for cough syringy
Candies from a cough - this, of course, is not a panacea, but a good remedy that helps to alleviate the pain that arises in the throat and chest. With their help, you can also stop seizures. Sweets are used for resorption from cough as an additional remedy. They are used in combination with anti-inflammatory, antitussive or expectorant drugs.What are lollipops from the throat and cough?
Reviews of candies from the throat and cough in most cases are positive. After all, practically all these products contain vegetable ingredients. It is about extracts of useful medicinal plants. There are other sweets for resorption, which include extracts of lemon, honey, and raspberries. Many consider them to be the best cough drops. These include the pastilles "Doctor MOM as well as candy "Hals." The price of these funds fluctuates around 60-120 rubles. Therefore, anyone can afford to buy such lollipops from a cough.
Sweets designed to soften the throat, usually prescribed with a dry cough. A symptom of this type is the most painful and debilitating. When wet, they are recommended for use only if the sputum has a thick consistency and leaves poorly.
Best cough drops herbal
According to reviews, the most effective are lollipops from cough on herbs. Here is a list of the best sweets for resorption, containing in their composition vegetable ingredients:
- Travisil. These resorption tablets come in several forms. The most common of these are lollipops with eucalyptus, black currant, mint and lemon. The main advantage of these pills is that they do not contain sugar, which means that they can be used for people suffering from diabetes.
- Doctor MOM. In the composition of herbal cough drops there are several medicinal plants at once: amblyca, licorice, ginger and menthol. These candies from cough and ginger are used to treat bronchitis, tracheitis and pharyngitis. They are also indicated for use in tonsillitis.
- "Sage". Lollipops with sage gently affect the throat and relieve the feeling of stuffiness. They also do not contain sugar. It is worth noting that these tablets have a specific taste.
- "Eucalyptus-M". These resorption tablets are shown not only to soften the throat, but also to relieve tension with vocal cords, so they are assigned to people whose work is related to the need to talk a lot or sing.
- "Falimint". Lollipops with an extract of menthol and eucalyptus can quickly soften the throat and stop the attack of dry symptom.
- "The Hills." Unlike previous drugs, these sweets are not a medicine. They contain sugar in their composition. Therefore, contraindicated for people with diabetes and high blood sugar. Candies with eucalyptus extract gently affect the vocal cords and for some time eliminate the feeling of stuffiness.
- Lacrimal tablets for resorption are considered to be among the most effective. They have a pleasant sweetish taste, but they do not contain sugar in their composition. Lacrimal sweets from the throat are indicated for use in bronchitis, tracheitis and tonsillitis.
- Mukoplant. This product contains extracts of honey and plantain. It has a positive effect on the composition of the sputum, making it less viscous.
It is important to know that some of the above described drugs have a number of contraindications, among which the children's age and the lactation period should be especially emphasized. Therefore, before using them, you should consult your doctor.
prokashel.ru
Advise resorptive candies from the throat (I have laryngitis, a region with unqualified doctors)
Answers:
Virus
There are many different "candy tablets" for treating throat. They all contain approximately the same set of active ingredients - usually 2 antiseptics, effective for to the main pathogens causing pain in the throat, some have additional components that improve their effects. To this group of drugs is Strepsils (Great Britain) - the first representative of this series, registered in Ukraine. The structure of Strepsils, in addition to antiseptics, includes honey, lemon and essential oils (peppermint, aniseed, orange), which have additional anti-inflammatory, analgesic and "cooling" effects. In the presence of diabetes it is necessary to take into account that only strepsils with lemon and herbs does not contain sugar.
In the subsequent, many drugs-analogues of Indian production - Adzysept, Vokasept, Gorpils (with honey, lemon or menthol and eucalyptus), Deinstril, Neo-Angin, Traicils were registered. Preparations are issued with various flavor additives - with orange, lemon, raspberry, honey taste. All of them are usually used for 2-4 days, if after that the pain in the throat does not go away, you need to go to reception of stronger antimicrobial agents for oral administration (selected with reference to a doctor's recommendation) .
Recently we have registered a new variant of Strepsils - Strepsils plus, in which In addition, a strong local anesthetic lidocaine (with allergies to lidocaine applies!). This drug is recommended for severe pain in the mouth and throat.
"Novelty" in a series of antimicrobial topical actions - tablets for resorption Trachsian, characterized by pronounced antimicrobial activity due to the presence in its composition of not only antiseptics, but also antibiotic tirotricin, harmful to microbes, some viruses and mushrooms.
"Distracting" effect for sore throats are lollipops containing menthol - Minton, Rondo and Tunes. They practically do not affect microorganisms and viruses that cause pain, but have an analgesic and refreshing effect. Anti-inflammatory effect is Lollipops with sage. With pains in the throat (angina, pharyngitis, coughing associated with them), you can take Dr. Mohm's lozenges containing licorice, essential oils and menthol, which reduce inflammation and pain.
Do not have a fruit taste, but have a good effect with sore throat tablets for resorption, containing a powerful antiseptic chlorhexidine. This drug acts not only on microbes, but also on fungi and some viruses, it enters the tablets for resorption of FERVEX from pain in the throat (contains only chlorhexidine), Sebidine (in addition, contains more ascorbic), Antiangin (has a strong analgesic effect due to the presence of the drug with local anesthetic activity and menthol). A similar formulation, but a more convenient dosage form (aerosol), has a preparation called Collustan. All these drugs are used in both ENT diseases, and in dental practice, with infectious lesions of the oral cavity.
Not bad proved to be the tablets for the resolution of Septotelet, also containing an antiseptic of a wide range of benzalkonium in combination with vegetable components - essential oils of mint, eucalyptus, plant antiseptic from thyme and menthol. A narrower spectrum of effects has Pectussin, containing only menthol and eucalyptus oil.
The natural antiseptic lysozyme, which has an antimicrobial effect against pathogens of the oral cavity, is contained in the preparations Hexaliz and Lisobakt. Each of them has its own characteristics: Hexalise has an anti-inflammatory and analgesic effect, as well as a stronger antimicrobial effect due to biclutymol - plant antimicrobial preparation from thyme, and Lysobakt improves metabolic processes due to the presence of vitamin B6, the need for which for catarrhal diseases increases.
Mom Serezha and Julia.
Strepsils. There are also tablets for resorption of Tharyngept.
Polly
doctor mom, and you can ask the pharmacist, a doctor doctor, and this one should know
Irina
Yes, strepsils are good, and they are also sugar-free, there is also a Falimint - a muck rare but effective.
Serg Sundukov
The best candies are strepsils. But with laryngitis vryatli they are effective. Go to the pharmacy and ask for an aerosol from the laryngitis. Eat more honey.
Anna
well, besides the candies, you still need to drink antibiotics or spatter. About strepsils and pharyngosept you already said, but I would still advise rinse your throat with chamomile (sold in a pharmacy already in bags) and buy ordinary candies, such as sucking candies, will suit even Chupa Chups.
Irina
Irrigation of the throat Tantum verde (eat in the pharmacy) and drink warm milk with soda (a glass half a teaspoon)
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Lollipops will not help. As well as strepsils (well, at worst, pharyngocept, but you will be treated for a long time) There is such a drug (tablets for resorption) - falimint. It's just for such cases. Helps to do well and quickly without putting the voice finally (We know, because we work on stage and laryngitis is our professional problem)
Tatyana
Milk drink do not advise! !
Alkaline inhalation! soda with water!
A candy is just the sea in pharmacies (on your budget)
Many of them have already advised you!
there are also "Laripront" - also good for pharyngolaringitis of any etiology.
PsihoParanoia
The best are the TRAVELS!!! ALWAYS dissolve only them. Pain removes like a hand!
Amelia Pond
Hexoral sprays buy or stopangin (it is burning, but effective). I got rid of laryngitis for 2 days using stopangin. Lollipops are long and often inefficient. In any case for me.
Yulia Vakula
I only use Tonzilotren. This is a safe and reliable homeopathy. Removes all symptoms of sore throat. For children, too, is suitable. They always help me.