Novobismol

Novobismol is an antiulcer drug with bactericidal activity against Helicobacter pylori.

It differs by pronounced astringent and anti-inflammatory actions. It belongs to the group of encapsulating and antacid agents based on bismuth.

Promotes the growth of the epidermis in the area of ​​the defect. It is used for the treatment of stomach ulcers, duodenal ulcer, chronic forms of gastritis and gastroduodenitis, functional dyspepsia.

Clinical and pharmacological group

A drug that has a protective effect on the mucous membrane of the stomach and duodenum. Antiulcer drug.

Conditions of leave from pharmacies

Released without a doctor's prescription.

Price list

How much does Novobispol in pharmacies cost? The average price is at the level of380 rubles.

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Form of issue and composition

Novobismol is manufactured in the form of biconcave round tablets, covered with a film coating creamy white. Tablets have a subtle smell of ammonia or do not have a smell at all. Each box contains 112 or 56 tablets, placed in contour cell packs (8 pieces each). From pharmacies is dispensed without a prescription.

In one tablet of the drug contains bismuth tricium dicitrate in the amount of 30 mg. In terms of bismuth oxide - 120 mg. Among the auxiliary substances are: corn starch (for structure formation), povidone (enterosorbent), macrogol (laxative), potassium polyacrylate (preservative), magnesium stearate (filler).

Pharmacological effect

It is an antiulcer drug with bactericidal activity against H. pylori. It has an astringent effect, besides it has anti-inflammatory properties. In the gastric acid medium, precipitation of insoluble citrate and bismuth oxychloride occurs, the formation of chelating compounds with a protein substrate in the form of a protective film on erosions and ulcers.

Promotes an increase in the synthesis of prostaglandin E, the formation of mucus, as well as the secretion of bicarbonate, and thus provides stimulation activity of cytoprotective mechanisms, increasing the resistance of the gastrointestinal mucosa to the action of bile salt, enzymes, hydrochloric acid and pepsin. Provides the accumulation in the defective area of ​​growth of the epidermal factor. Helps reduce pepsinogen and pepsin.

Indications for use

Among the indications for the use of Novobismol, various diseases of the digestive tract are distinguished. These include:

• functional dyspepsia;
• stomach ulcer and duodenal ulcer, including the stage of exacerbation;
• exacerbation of chronic gastritis, gastroduodenitis;
• irritable bowel syndrome, flowing with symptoms of diarrhea.

Contraindications

Novobismol in tablets is contraindicated:

• during lactation;
• during pregnancy;
• if the patient has an individual intolerance of the main active and auxiliary components of the drug;
• with violations of the kidneys;
• children under 4 years.

Use in pregnancy and lactation

The active substance does not have teratogenic, mutagenic and embryotoxic properties, but the data confirming its absolute safety for the fetus is not enough. In this regard, women during the gestation period (at any time) this antiulcer is contraindicated.

If it is necessary to conduct course therapy during lactation, the question is raised about transferring the baby to artificial feeding.

Dosage and route of administration

The instructions for use indicate that Novobismall tablets should be taken with a small amount of water.

• Children aged 8 to 12 years, the drug is prescribed to 1 tablet. 2 times / day for 30 minutes before a meal; children aged 4 to 8 years - at a dose of 8 mg / kg / day; The daily dosage is divided into 2 doses, taken 30 minutes before meals.
• Adults and children over 12 years of age, the drug is prescribed 1 tablet. 3 times / day for 30 minutes before meals and 1 tab. at night or 2 tab. 2 times / day for 30 minutes before meals.

Duration of treatment 4-8 weeks. For the next 8 weeks, do not use drugs containing bismuth. For the eradication of Helicobacter pylori, it is advisable to use bismuth tricalium dicitrate in combination with other antibacterial agents possessing anti-Helicobacter pylori activity.

Side effects

Side effects in patients taking Novobismol are rare. However, in some cases, the following reactions are possible:

1. Allergic: redness of the skin, itching, rash.
2. From the gastrointestinal tract: transient effects - vomiting, constipation, nausea, frequent stools. Such phenomena are temporary and not dangerous to health.
3. Others: encephalopathy is the result of accumulation in the central nervous system of bismuth. Occurs with prolonged uncontrolled use of the drug.

During application, staining of fecal matter can occur in black. This is due to the formation of bismuth sulphide. In rare cases, there is a slight darkening of the tongue.

Overdose

In the case of an overdose of Novobismol, as a result of prolonged doses that are greater than those recommended, there may be a violation of renal function. These signs are reversible completely, if you cancel the drug. If there are signs of poisoning with this drug, you should wash the stomach, take salt laxatives, in addition, and activated charcoal.

Further therapy should be symptomatic. If there is a violation of renal function, which is accompanied by a high content of bismuth in the blood plasma, complexing agents, i.e., dimercaptopropane sulfonic and dimercaptosuccinic acid. With severe renal function disorders, hemodialysis is indicated.

special instructions

Before you start using the drug, read the special instructions:

1. The drug should not be used for more than 8 weeks.
2. During the treatment period, other preparations containing bismuth should not be used.
3. When Novobismol is used, it is possible to stain the stool in a dark color due to the formation of bismuth sulphide. Sometimes there is a slight darkening of the tongue.
4. At the end of the course of treatment with the drug at recommended doses, the concentration of the active substance in the blood plasma does not exceed 3-5.8 μg / l, and intoxication is observed only at concentrations above 100 mcg / l.
5. It is also not recommended during the treatment with Novobysmol to exceed the prescribed daily doses for adults and children.
6. When eliminating unused packages of the drug, special precautions are not required.

The drug does not affect the ability to drive and other mechanisms.

Drug Interactions

The first 30 minutes after taking Novobispol not allowed to use other medicines, liquids, food, especially containing antacids, fruits, fruit juices and milk.

Some drugs and products may affect the therapeutic effectiveness of Novobismol.

Reviews

We picked up some reviews of people using Novobismall:

1. Tatyana. Last year, a course of treatment with novobismol, was given acute gastritis. A good drug, quickly removed the pain, a feeling of nausea. The fact that the prescribed treatment helped, was also convinced at the repeated FGD. During the treatment, I followed all the doctor's recommendations, and on a diet as well. Now I can afford to eat everything, but I still try to adhere to proper nutrition.
2. Peter. Even in the army, I earned myself a gastritis, which has already become chronic. Exacerbations occur rarely, but always suddenly and cause great discomfort. To cope with them, I drink Novobismol tablets, which the doctor advised me. True, they became weaker by effect than before, can the body get used to it? I will look for another effective tool.
3. Kirill. I always took a denal from gastritis, but he lost something from our pharmacies, they say that because of sanctions, the import was. Well, okay. After the holidays, my stomach got sick again. I went to the doctor in charge, asked what can be replaced, Novobismol prescribed, in composition one-on-one, bought a package of 56 tablets, this is for two weeks until the third day the stomach stopped hurting, although some discomfort remained, for a full recovery, you need to drink the whole course, at least 28 days. So I did, strictly by the hour, the truth is not 4 times a day, but twice on two tablets for an after-sleep. The course of admission has finished, I do not feel any diskomofrta in the stomach.

Analogues

There are a number of analogs of the drug in question, similar to it in terms of active composition. These include:

• Ankrusal, Venter, Ulgastran - gastroprotectors based on sucralfate;
• Alsukral - antiulcer medication;
• Ventrisol is a direct analogue of the drug;
• Bismuth titanium dicitrate is a direct substitute in tablets;
• Bismuth nitrate basic - a combined antacid drug;
• Neointestopan, Kaopectat - antidiarrheal adsorbents with attapulgite in the composition;
• Sukrat is a gastroprotective gel;
• Sucralfate is an antacid and an absorbent based on an aluminum complex;
• De-Nol is a structural analogue, completely identical in properties.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Packings with tablets should be stored in dark places with a low level of humidity at a temperature of no more than + 25 ° C.

If the storage rules are observed, the expiry date is 48 months.

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