Clenzite C from acne and acne: instructions for use

Clenzite C is an external drug for the treatment of acne. The mechanism of its action is determined by the constituent components.

The active ingredient is adapalene, the main function of which is to reduce sebum secretion. The fact is that the cause of acne is bacteria, for which sebum is an excellent habitat. Thanks to adapalene, the process of drying out old acne occurs, and the process of occurrence of new rashes is also suppressed. Also, Clenzite gel helps to narrow the pores.

On this page you will find all the information about Clenzite C: full instructions for use for this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as feedback from people who have already applied Clenzite S. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

The drug for the treatment of acne with comedonolytic and antibacterial action.

Conditions of leave from pharmacies

Available without a prescription.

Price list

How much does Clenzite C cost? The average price in pharmacies is at the level of600 rubles.

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Form of issue and composition

Gel for external use Clenzite C for 15 or 30 g in tubes made of laminated foil, in a pack of cardboard, insert 1 tube.

The active substances are:

adapalene, which is a retinoid, that is, a synthetic analogue of retinoic acid, 1 mg per gram of "Clenzite C" gel from acne;
clindamycin in a ratio of 10 mg per 1 gram of the drug.

Auxiliary components:

propylene glycol;
disodium edetate;
Carbomer 940;
sodium hydroxide;
purified water;
methylparahydroxybenzoate;
phenoxyethanol;
poloxamer 407.

Pharmacological effect

Means for acne "Clenzite" refers to combined drugs, where active substances are adapalene and clindamycin.

Antibiotic Clindamycin- belongs to the group of lincosamides; is very effective against bacteria that lead to suppuration of the hair follicles (i.e., to the formation of acne). When appointing, it is necessary to take into account cross resistance: if the bacteria were not sensitive to the antibiotic Linkomycin, they would not be sensitive to Clindamycin either. In this case, it is necessary to prescribe gels containing an antibiotic of another group, for example, erythromycin.
Adapalen- Retinoid metabolite, which has an anti-inflammatory effect and pronounced comedonolytic activity (affects to open and closed comedones), normalizes the processes of keratinization and epidermal differentiation. The mechanism of action of the drug is based on the binding of adapalene to specific nuclear receptors of retinoic acid. Adapalen normalizes the process of differentiation of the epithelial cells of the follicles, thus reducing the formation of microcosmodes. Suppresses chemotaxis and chemokinetic reactions of polynucleated cells in humans, and also inhibits the metabolism of arachidonic acid and the formation of inflammatory mediators. Thus, it can be said that under the influence of adapalene, the cellular-mediated inflammatory component of acne is reduced.

Indications for use

The annotation accompanying the gel explains that the main indication for its use is the treatment of acne and acne of all degrees of severity and form, which explains its universality.

Contraindications

Absolute contraindications:

pregnancy and lactation;
age up to 12 years;
increased sensitivity to any of the components of the drug.

In the combination therapy with clindamycin (oral, intramuscular, intravenous), the Clenzite-C gel is contraindicated for ulcerative and pseudomembranous colitis, in the anamnesis, and Crohn's disease.

Relative contraindications:

eczema;
dermatitis;
allergic diseases;
joint reception with muscle relaxants.

Application in pregnancy and lactation

The use of Clenzite C in women during pregnancy and lactation is not recommended due to the lack of necessary clinical studies of the drug in this category of patients.

Instructions for use

In the instructions for use, it is indicated that the Clenzite C gel is applied externally. Before applying the Clenzite-C gel, you must clean and dry the skin.

With a gentle touch, apply the gel evenly to the affected areas of the skin 1 time a day before bedtime, avoiding getting the drug into the eyes and lips. The therapeutic effect develops after 1-4 weeks. The course of therapy is 2-4 weeks. A persistent improvement comes after a 3-month treatment. Repeated courses of treatment - after consultation with a doctor.

Use the drug only according to the method of administration and at the doses specified in the instructions for use. If the gel is applied excessively, the positive effect does not occur sooner.

Side effects

In a number of cases, the occurrence of side effects due to the use of the drug "Clenzite". Gel from acne, the reviews about which are the most positive, can provoke a strong dryness of the skin, and also cause itching, burning, flushing, irritation and redness. In the event of such a situation, it is necessary to temporarily suspend the use of the drug and continue the therapeutic course after the complete disappearance of side effects.

Often there is an ecdysis. It arises from the effects of retinoids on the skin. In this case, it is recommended to lubricate the surface of the skin with a moisturizing cream 30 minutes after applying the drug.

Sometimes there is an aggravation of acne, which during treatment passes. There were cases of allergy to the drug and individual intolerance of the drug, but such situations were rarely observed.

Overdose

With external application, the development of an overdose of Clenzite C is unlikely.

At casual oral reception it is necessary to spend immediately lavage of a stomach and to accept enterosorbent agents.

special instructions

Avoid contact with the eyes, oral cavity, nasal cavity and other mucous membranes. If the product is accidentally ingested in the eyes, mouth or nose should be rinsed immediately with warm water.
At the initial stages of treatment, there may be an aggravation of acne, which disappears during the treatment. If the skin irritates, stop using the gel (temporarily or completely).
It is not recommended simultaneous use of cosmetic products with drying or irritating effect (for example, cologne, perfume and other alcohol-containing products).
Excessive exposure to sunlight or UV radiation should be avoided. In the case of prolonged exposure to the sun, do not apply the gel the day before, as well as on the day of the solar exposure and the subsequent day.

With external use of clindamycin, the occurrence of diarrhea and colitis is extremely rare, nevertheless, caution should be exercised, and with development severe or prolonged diarrhea, the drug should be discontinued and, if necessary, carried out the appropriate diagnostic and treatment measures. Pseudomembranous colitis can appear both on the background of long-term use, and 2-3 weeks after cessation of treatment; is manifested diarrhea, leukocytosis, fever, abdominal pains (sometimes accompanied by secretions with fecal masses of blood and mucus).

When these phenomena occur in mild cases, it is sufficient to cancel the treatment and apply ion-exchange resins (colestyramine, colestipol), in severe cases, compensation for loss of fluid, electrolytes and protein, the appointment of vancomycin inwards or metronidazole is indicated. Do not use drugs that inhibit intestinal motility.

Drug Interactions

When using the drug Clenzit in the evening, it is allowed to use other anti-acne medications in the morning.

It is not recommended simultaneous use of the drug Clenzite with irritating and drying agents (including cologne and other alcohol-containing products).

Combined use of adapalene with clindamycin and benzoyl peroxide is acceptable.

Reviews

We picked up some feedback from people about the preparation of Clenzite C:

Nadia. Used 4 weeks, as written in the instructions. At first there was a burning sensation, but not fatal. The first 2 weeks were terrible: the entire face was red with a lot of inflammation, everything was peeling and softening cream did not help (but then began to use simple children's cream, it became better), also it was impossible to touch the face (there were painful sensations at a touch with any surface). Another 2 weeks later, the side effect started: in the morning my eyes were swollen and flaky (((, so I stopped using it for 2 days. But despite all this, I endured to the end. In the end: the skin seems to have cleared, but there are still inflammations on the cheeks (((, I think that this is due to the fact that at night the medicine was wiped off about the pillow, in the end, these zones are now healing (I'm only now spreading it not at night, but right after the institute and I'm sitting at home, like helping on the sly). Honestly, the drug is very good, this effect I have not yet white from any other, so that ADVICE))) It is worth a little patient, to experience this feeling of freedom from the eternal problem))).
Liuba. Every year in the summer, probably because of the heat, all the back was covered with pimples. They bothered me badly, combed it to blood, but there are more and more of them. The dermatologist prescribed gel "Clenzite C", mazyala before going to bed, absorbed well. A few days later the skin began to peel off, to peel off. I thought that the skin peels after sunburn. The doctor explained that the gel can not always be used, only by courses. A skin peeling is a normal process. In the future, you can use the gel "Clenzite", it is not addictive.

Analogues

Clenzite-C analogues are Clindex, Zinerite, Skinoren, Resorcin, Aziks-Derm, Azelik.

Before using analogues, consult your doctor.

Storage conditions and shelf life

The medicament is stored at a temperature of not more than 25 gr C in a dark place, remote from small children. The medicine is allowed to be used within 2 years from the moment of its release.