When Xylen drops are prescribed: instructions for use

Xylen - alpha-adrenomimetic; vasoconstrictor, intended for topical application in ENT practice.

The use of Xylene leads to narrowing of the blood vessels of the mucous membranes of the nose and contributes to: nasal passages, elimination of hyperemia (blood vessel overflow) and edema of the nasal mucosa, alleviation of the nasal respiration.

The action of the drug develops rather quickly (within a few minutes after the application of the spray or drops), the duration is up to 10 hours.

Clinical and pharmacological group

Vasoconstrictor for topical application in ENT practice. Alpha-adrenomimetic.

Conditions of leave from pharmacies

Released without a doctor's prescription.

Price list

How much does Xylen cost? The average price in pharmacies is at the level of30 rubles.

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Form of issue and composition

Xylenes are produced in the form of:

• Nasal, 5% and,% spray (clear, colorless liquid) with a content of 1 ml 500 μg and 1 mg respectively xylometazoline hydrochloride and auxiliary substances: purified water, disodium edetate, sodium dihydrogen phosphate dihydrate, sodium hydrogen phosphate dihydrate, sodium chloride, benzalkonium chloride. In dark vials with a sprayer of 10 ml and 15 ml;
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• Nasal, 5% and,% drops (clear, colorless liquid) with a content of 1 ml 500 μg and 1 mg respectively xylometazoline hydrochloride and auxiliary components: sodium hydrophosphate dodecahydrate, benzalkonium chloride, sodium chloride, disodium edetate, potassium dihydrogen phosphate, water purified. In the bottles-droppers of 10 ml.

Pharmacological effect

The active substance of the drug is Xylometazoline hydrochloride. It is an alpha-adrenomimetic of indiscriminate action. In small doses, it acts on alpha1-adrenergic receptors, in large doses - on alpha2-adrenergic receptors. When in contact with the nasal mucosa, reduces blood vessels, reduces the intensity of inflammation and exudation. Reduces the nose from redness and swelling. It facilitates breathing through the nose in rhinitis.

With nasal use, xylometazoline almost does not enter the bloodstream. It is well tolerated even in people with high sensitivity of the nasal mucosa.

Indications for use

Due to its actions the drug is popular in the treatment of ENT diseases. It is assigned to both adults and children.

Usually, Xylen is prescribed for the following diseases:

1. Rhinitis in acute form;
2. Pollinosis;
3. Sinusitis;
4. Etmoiditis;
5. Sphenoiditis;
6. Otitis of the middle ear;
7. Rhinitis of allergic etiology.

When otitis, you must also dig in the nose, not the ear canals. There is an opinion that Xylen can be used as eye drops, however, in the eye disease instruction Do not refer to the indications, on the contrary, it is not recommended to use the drug for patients in the presence of glaucoma.

It is also recommended to use the drug with abundant discharge from the nose and its obstruction, which are a sign of various respiratory and viral diseases. Xylen is used after surgical interventions on the nose, as well as before some medical procedures, for example before rhinoscopy.

Contraindications

Absolute:

• Surgical interventions on the meninges in the anamnesis;
• Children under 2 years old - for, 5% spray, up to 6 years - for,% drops and spray;
• Lactation (or should stop breastfeeding);
• Atrophic rhinitis;
• Severe arterial hypertension;
• Tachycardia;
• Severe form of atherosclerosis;
• Glaucoma;
• Individual hypersensitivity to xylometazoline or accessory components of the drug.

Relative (special care is required):

• Diabetes;
• Benign prostatic hyperplasia;
• Cardiac ischemia;
• Hyperthyroidism;
• Pregnancy.

Use in pregnancy and lactation

During pregnancy and lactation should be used only after a thorough assessment of the risk-benefit ratio for the mother and fetus, do not exceed the recommended dosage.

Dosage and route of administration

The instructions for use indicate: spray and Xylene droplets are intended for intranasal use. Before each administration of the drug, it is necessary to clean the nasal passages from the mucus.

• The minimum interval between applications is 8 hours. Duration of treatment is determined by the attending physician, but it should not exceed 5 days.

Recommended doses:

1. Adults and children older than 6 years - 1-2 drops,% drops or 1 injection,% spray in each nasal passage 2-3 times a day;
2. Children 2-6 years - 1-2 drops, 5% drops or 1 injection, 5% spray in each nasal passage 1-2 times a day;
3. Children from birth to 2 years - 1-2 drops, 5% drops in each nasal passage 1-2 times a day.

If the patient misses the time of drug administration, the dose can not be doubled by the following procedure.

Side effects

With frequent and / or prolonged use of the drug, the following side effects are possible: irritation of the mucous membrane, burning, tingling, sneezing, dryness of the mucous membranes, hypersecretion.

Sometimes the Xylene intake is accompanied by swelling of the nasal mucosa (usually with prolonged use), palpitation, heart rhythm disturbances, increased blood pressure, headache, vomiting, sleep disorders, impaired vision.

With prolonged use in high doses, depression may occur.

Overdose

Cases of drug overdose occur in rare cases with the recommended dose. With the uncontrolled use of drops in the nose and the use of the drug for more than 14 days, the patient has systemic signs of an overdose:

1. Pain in the temples and occiput;
2. Increased blood pressure;
3. Depressive disorders;
4. Constant drowsiness and apathy to what is happening;
5. Lethargy and fatigue;
6. Dizziness;
7. Strengthen the above-described side effects.

With the development of such clinical symptoms, the patient should immediately give up the drug and consult a doctor. If necessary, a treatment aimed at eliminating symptoms of an overdose is performed.

special instructions

Do not use for a long time, for example, with chronic rhinitis. In case of colds, in cases where crusts form in the nose, it is preferable to prescribe in the form of a gel.

Caution is prescribed xylometazoline to children under 2 years of age (gel - up to 7 years).

Drug Interactions

Incompatible with MAO inhibitors and tricyclic antidepressants.

Reviews

We picked up some reviews of people taking Xylen:

1. Catherine. Yes, drops are cheap, but not always they can be found in the pharmacy. This is such a minus. I switched to these drops from naphthyzine. At the cost, of course, there is no benefit. But I like the effect more. Xylenes can be buried one time, and all will be a minimum of half a day. But it still causes a slight dryness in the nose, so very often I do not dig it. If you compare it all with the same naphthyzine, then a huge plus, that these drops are not addictive.
2. Vadim. Good cheap drops, help with cold and chronic nasal congestion. They act quickly and after a couple of minutes the nose starts to breathe. And re-instillation is required hours in 10 only, not like with other drops almost every half hour. In my opinion - in comparison with other drops Xylen wins in everything.
3. Sasha. Often stuffy nose. And "Xylen" directly saves me. Doubtful pluses: a plastic bottle (not scary to break when you throw in your purse, very gently removes zalozhennost, the price (the average chen in all drugstores of my city of 20 rubles, by today's measures it not money). Cons: slow action. If you need a nose to breathe quickly, then "Xylen" is not suitable, since it can be stored up to half an hour. Also, if you eat at least 2-3 times a day, your nose starts hurting. But this is not surprising.

Analogues

Xylen analogues include medicines:

• On the active substance - Influrin, Rinonorm, Otrivin, Ximelin, Rinorus, Galazolin, Vnanos, Espazolin, Pharmazoline, Rhinomaris, Sialor, Xylometazoline, Nosolin, Snoop, Rhinostop, Influrin;
• On the mechanism of action - Nesopin, Oksimetazolin, Sanorin, Rinosprey, Nazivin, Nazol, Naftizin, Nazosprey, Sanorinchik, Afrin, Naphthyzin.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Store in the original packaging at a temperature of 15 to 25 ºC.

Shelf life - 3 years.

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