Stoppier

Stoediar (the active ingredient is nifuroxazide) is an antidiarrhoeal drug, a derivative of nitrofuran.

Has antimicrobial activity against bacteria of the gastrointestinal tract, among which there are both gram-positive (Staphylococcus spp.) and gram-negative (Escherichia spp., Enterobacter spp., Citobacter spp., Yersinia spp., Salmonella spp.) "characters".

Stoppier is impotent for infections caused by Klebsiella spp., Proteus mirabilis, Proteus vulgaris and Pseudomonas aeruginosa.

Clinical and pharmacological group

Antibacterial drug, a derivative of nitrofuran. Antidiarrhoeal drug.

Terms of sale from pharmacies

Can buyby prescription.

Price

How much does the Stopdiary cost in pharmacies? The average price is at the level of220 rubles.

Composition and form of release

The suspension is available in 90 ml bottles complete with a measuring spoon (2.5 / 5 ml). In addition to the active substance (nifuroxazide - 220 mg in 5 ml of the drug), the agent contains auxiliary components:

carbomerum (carbomerum) - is a regentant capable of replenishing the lack of fluid in the body;

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sucrose sweetener;
caustic soda;
citric acid;
mixture polydimethylsiloxane and silicon dioxide - antifoam component;
methyl ester of para-hydroxybenzoic acid - preservative;
aroma "banana";
water.

The suspension is a thick liquid of lemon color with a banana taste. The manufacturer warns of the possibility of precipitation, which can be eliminated by shaking the bottle with syrup.

pharmachologic effect

The drug has a harmful effect on microorganisms that cause fluid stools, vomiting, diarrhea and other intestinal disorders. To the influence of nifuroxazide, such microorganisms are sensitive:

shigella;
Proteins;
Yersinia;
E. coli;
staphylococci;
salmonella;
citrobacter;
Klebsiella;
cholera vibrio,
enterobacter.

Stopdiar therapy of viral diseases caused by the listed bacteria, prevents the development of superinfection. It is important to note that the Pseudomonas aeruginosa and the proteus Proteus inconstans type are insensitive to nifuroxazide.

Taking medication in small doses acts bacteriostatically. Nifuroxazide inhibits the respiratory function of pathogenic bacteria, disrupts metabolic processes in their cells and the ability to reproduce themselves. Such influence makes aggressive microorganisms unviable.
Large doses of the drug are bactericidal. The active substance destroys the cell membranes, resulting in pathogenic bacteria rapidly dying.

In addition, the drug reduces the synthesis of toxins produced by the above microorganisms. The reception of Stopdiar does not provoke the emergence of resistant bacteria that are not susceptible to nifuroxazide and other drug drugs, which makes it possible to simultaneously take the described drug with other medicines against diarrhea. The sensitivity of pathogenic microorganisms to nifuraksozid does not decrease even with its long-term use. The quality of the drug's effect does not depend on the acidity of the environment, where it works.

The stoppier destroys mutant strains that are immune to the effects of antibiotics. Simultaneously, it does not disturb the balance of microorganisms that make up the natural intestinal microflora. Therefore, after the completion of the course of treatment of diarrhea with such a drug, it is not necessary to take medications that restore the intestinal microflora, which are necessary after antibiotic therapy.

Indications for use

The main medical indication for the reception of a suspension of Stopdiar is etiotropic therapy of diarrhea with an acute or chronic course of the pathological process, caused by various bacteria that are sensitive to nifuroxazide (E. coli, streptococci, proteus, klebsiella, enterobacter, hemophilic rods).

Contraindications

Contraindications for the use of tablets:

allergy to drugs from the group of 5-nitrofuran derivatives;
increased sensitivity of the organism to other components of the drug;
age to six years.

Contraindications for the use of suspension:

allergy to drugs from the group of 5-nitrofuran derivatives;
increased sensitivity of the organism to other components of the drug;
age up to two months;
prematurity.

With caution, it is recommended to take the medicine during pregnancy and lactation of the baby, as there have been no clinical trials in these categories of patients.

Dosage and route of administration

As indicated in the instructions for use, the suspension of Stopdiar should be taken at regular intervals, regardless of the intake of food. The duration of therapy is 5-7 days.

Recommended dosage regimen based on the patient's age:

from 2 to 6 months: 2 times a day for 1-2 scoops for 2.5 ml;
from 6 months to 6 years: 3 times a day for 1 measuring spoon for 5 ml;
from 6 years and older: 4 times a day for 1 measuring spoon for 5 ml.

One measuring spoon with a capacity of 2.5 ml contains 110 mg of nifuroxazide, 5 ml - 220 mg.

Before using the preparation, the vial should be shaken thoroughly until a homogeneous suspension is obtained.

Side effect

digestive system: increased diarrhea, nausea, short abdominal pain;
others: single cases - itching, skin rashes, dyspnea.

The appearance of these disorders does not require the cancellation of the suspension of Stopdiar.

Overdose

Cases of overdose Stopdiar have not been registered to date. If this condition is suspected, gastric lavage and symptomatic treatment should be performed.

special instructions

Before starting treatment, read the special instructions:

The drug is not prescribed as a monotherapy for the treatment of intestinal infections complicated by septicemia.
Before the suspension is prescribed to infants, it is necessary to exclude from them an inborn deficiency of enzymes that break down sucrose.
During the treatment should adhere to a certain diet: do not eat raw fruits and vegetables, juices, spicy and fatty dishes.
If there are symptoms of dehydration, it is necessary to carry out rehydration therapy with adults (about 2 liters of fluid per day).

During treatment Stopdiar contraindicated the use of alcoholic beverages, tk. alcohol increases the sensitivity of the body to the drug and can provoke a disulfiram-like reaction, expressed by exacerbation of diarrhea, vomiting, abdominal pain, skin flushing, a sensation of heat on the face and upper body, noise in the head, shortness of breath, tachycardia, a sense of fear.

Interaction with other drugs

During treatment Stopdiar should avoid simultaneous oral administration because of the strong adsorption properties of the drug.

Since nifuroxazide does not enter the circulatory system, interaction with systemic drugs is unlikely and is still unknown.

Reviews

We offer you to familiarize yourself with the opinions of people who used the drug Stopdiar:

Catherine. We tried, the child had an allergy on the third day. More will not give. Remained unhappy. He did not help us.
Valentina. We also happened to use a stopcore, I agree, he helps diarrhea, our daughter is 1 year old, picked up the infection in the children's hospital, thought at first that diarrhea from antibiotics, but no, on the first day of use the chair became thicker, quietly normalized. but from him we even more heavily sprinkled the legs and elbows at the daughter, so you need to be more careful than children prone to allergies, the drug is really good for children, it tastes good.
Olga. The irreplaceable thing in my home medicine cabinet. Helped repeatedly to a child with small indispositions associated with the use of poor-quality food, there was only 2-3 reception of this remedy. He treated the child and the husband with a strong intestinal infection. In this case, I had to use it a little more long, about 5 days. They were taken in the form of a syrup having a banana flavor.

Analogues

The structural analogues of Stopdiar containing the same active substance are the following preparations:

Nifuroxazide;
Enterofuryl;
Ersefuril;
Ecofuril.

Among other medicines with a similar therapeutic effect, one can name drugs Furazolidone, Levorin, Entoban, Sanguirithrin. The decision to replace Stopdiara with analogs should be the attending physician.

Shelf life and storage conditions

The tablets are stored in a dry, dark place, at a temperature of 15-25 ° C. The suspension should be stored at a temperature of no higher than 25 ° C. Medicinal products should be inaccessible to children.

Shelf life of the tablets is 4 years, the suspension is 3 years.