Riboxin

Riboxin - a drug that regulates metabolic processes in the myocardium, reducing tissue hypoxia, improving coronary circulation.

Has antihypoxic, metabolic and antiarrhythmic effect. Increases the energy balance of the myocardium, improves coronary circulation, prevents the consequences of intraoperative kidney ischemia.

It takes a direct part in the exchange of glucose and promotes the activation of metabolism in conditions of hypoxia and in the absence of adenosine triphosphate.

Clinical and pharmacological group

A drug that normalizes the metabolism of the myocardium, which reduces tissue hypoxia.

Terms of sale from pharmacies

You can buy without a doctor's prescription.

Price

How much does Riboxin cost in pharmacies? The average price is at the level of60 rubles.

Composition and form of release

Traditionally, the drug is produced in the tablet form factor, which is covered with a special film membrane. The color of the tablets varies from yellowish to yellow-orange. The tablets are biconvex, round, slightly rough, with a cut it is seen that the core has a white color.

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The main substance of the drug is inosine. There are also auxiliary substances, including stearic acid, methylcellulose, potato starch and sucrose. The shell also contains opahedra II of yellow color.

Alternative form of release - capsules with 2% solution, which are used when injections of this drug are made.

pharmachologic effect

Inosine, which is the active substance of Riboxin, helps to regulate metabolic processes. The drug has antihypoxic and antiarrhythmic action. It is able to accelerate metabolic processes in the myocardium and positively affect the metabolic processes in the cardiac muscle. In addition, it helps to adequately relax the heart muscle during diastole.

The active substance Riboxin takes part in glucose metabolism and helps to restore ischemic tissue, and also stimulates the normalization of blood circulation in the coronary vessels. Treatment with this drug helps to reduce tissue hypoxia and activate all metabolic processes in the myocardium.

Indications for use

Lkx appoint it? To apply prescribed by a doctor Riboxin, with different dosages, the patient has for many reasons:

Prolonged excessive physical activity, negatively affecting the body as a whole;
Riboxin is in demand in sports, to support professional athletes during long training sessions;
Indications for use are in the diagnosis of uroporphyria (metabolic functions are impaired);
Supplements the basic composition of medicines in the treatment of open-angle glaucoma;
Riboxin is indicated in oncology, for the duration of radiotherapy, which facilitates the perception of the procedure and a decrease in the adverse response to it;
In the complex treatment of IHD (ischemic disease). The start of the medication intake is possible regardless of the phase of the disease, and in the process of the recovery period after the happened myocardial infarction;
Myocardium and cardiomyopathy initiate indications for long-term admission of riboxin;
With the normalization of the rhythm of the heartbeat (arrhythmia). The best effect is achieved in the treatment of pathology, provoked by an overdose of individual drugs;
Complex drug therapy for liver pathology: cirrhosis, fatty degeneration, hepatitis, a manifestation of toxic violations in the cells of the liver (the consequence of taking medications, complications in the performance of professional duties);
Prescribe Riboxin during pregnancy, at the discretion of the treating doctor.

Contraindications

hyperuricemia;
gout;
glucose / galactose absorption disorder syndrome, fructose intolerance or isomaltase / sucrose deficiency (for film-coated tablets);
age to 18 years;
period of pregnancy and breastfeeding;
hypersensitivity to the constituents of the drug substances.

Caution when prescribing Riboxin should be observed in the presence of the following diseases / conditions:

kidney failure;
diabetes mellitus (for film-coated tablets).

Intended use for pregnancy and lactation

Riboxin in pregnancy is prescribed for many women. Many patients are frightened by the fact that in the instructions to the drug it is often possible to meet information that the drug is contraindicated for pregnant women. However, this should not be frightened, since the contraindication is based on the fact that clinical studies in this area have not yet been carried out. And this is despite the fact that today there is a lot of experience in the successful use of Riboxin in the period of gestation. The medicine does not have a pathological effect on the fetus or on his mother, so there is no reason for fear. The only contraindication here can be only individual intolerance to the drug or its components.

Riboxin is an antihypoxant, an antioxidant, and a good means of improving metabolic processes in tissues, which is especially important in the period of gestation.

The drug is prescribed to prevent heart disease and support cardiac activity during the period of increased stress. Often, Riboxin is administered directly during childbirth, since the load on the heart at such a time is particularly great.

Medication doctors often appointed in the presence of pregnant gastritis and liver diseases in order to treat existing problems. The drug helps to normalize the secretion of the stomach and reduce unpleasant symptoms.

Riboxin during pregnancy the doctor can appoint or nominate in case of revealing a hypoxia of a fetus. Normalizing metabolic processes in tissues, the drug reduces the degree of oxygen starvation of the fetus.

With good tolerability, the drug future mothers take inside 1 tablet 3-4 times a day for 1 month. Despite the harmlessness of the medication, as in any other case, Riboxin should be prescribed by a physician strictly on an individual basis.

Dosage and route of administration

As indicated in the instructions for use, prescribe Riboxin to adults inside, before meals.

The daily intake dose is 0.6-2.4 g. In the first days of treatment, the daily dose is 0.6-0.8 g (200 mg 3-4 times a day). In case of good tolerance, the dose is increased (2-3 days) to 1.2 g (0.4 g 3 times a day), if necessary - up to 2.4 g per day.
The duration of the course is from 4 weeks to 1.5-3 months.

With urocoppororphy, the daily dose is 0.8 g (200 mg 4 times a day). The drug is taken daily for 1-3 months.

Injection solution

Methods for the introduction of Riboxin: intravenously struino slowly or drip (in 1 minute 40-60 drops).

The initial dose - once a day for 10 ml of the solution (200 mg of inosine), if the therapy is well tolerated by the patient, a single dose is increased 2 times with a frequency of 1-2 times a day. The duration of the drug is 10-15 days.

Injury administration of Riboxin is possible with acute violations of the heart rhythm, a single dose - from 10 to 20 ml.

For the purpose of pharmacological protection of exposed kidney ischemia, the drug is administered intravenously in a jet: for 5-15 minutes of switching off blood circulation by squeezing the artery of the kidney - 60 ml, and then another 40 ml immediately after the blood circulation is restored.

For the dropwise administration, Riboxin solution should be diluted to a volume of 250 ml (5% glucose solution (dextrose) or 0.9% sodium chloride solution).

Side effect

Side effects are possible, so after the first intake of the drug you need to carefully monitor the patient's condition. Riboxin can cause the following undesirable reactions:

Headache, nausea, vomiting.
Exacerbation of gout, hyperuricemia.
The general weakness.
Allergic reactions (including immediate type).
Rash, itching, changes in skin.
Increased palpitations and a drop in blood pressure.
Dizziness, increased sweating.
Discomfort at the injection site.

If side effects occur, the drug is canceled.

Overdose

Currently, cases of an overdose of Riboxin tablets have not been established.

special instructions

During the treatment with Riboxin, the concentration of uric acid in the blood and urine should be monitored.

Information for patients with diabetes: 1 tablet of the drug corresponds to 0.00641 units of bread.

Does not affect the ability to drive vehicles and manage mechanisms that require increased concentration.

Interaction with other drugs

Pharmacological interaction, mainly, manifests itself with preparations of other cardiac groups. Riboxin can enhance the effect of heparin, since it itself affects the aggregation of platelets.

It also enhances the inotropic effect of cardiac glycosides and prevents the occurrence of arrhythmias.

With the simultaneous administration of a group of beta-blockers with drugs, the action of Riboxin does not change. It is also possible to combine it with nitroglycerin, spironolactone, nifedipine, furosemide.

The solution is not compatible in one container with pyridoxine, salts of heavy metals, alkaloids, acids. Mix with other solvents, except recommended, Riboxin can not.

Reviews

We offer you to familiarize yourself with the reviews of people using Riboxin:

Lena. Riboxin is an old, kind, time-tested drug. Many believe that this is the last century, as many newer means have appeared, but my mother trusts only him and does not intend to switch to another drug. Only we buy either Russian or Belarusian production
Sasha. At me on a background of a bed regimen (hemarthrosis kolena.razryt ligament) hypotension developed-pressure 90 on 50 at the normal 120 on 80. drank ginseng and other stimulating means of increasing the pressure-nifiga no result. (weakness, nausea, pain in the heart, extrasystoles, darkening in the eyes and remained) three days of drinking riboxin by 1tab. 2 times a day all the symptoms went away and the pressure increased to 110 by 70.
Valeria. I do not remember when it was exactly, but I will remember the situation for a long time! My daughter's daughter suffers from heart disease and always takes some medicine. Once we left her with my grandmother and Inga started an attack.. Grandmother, in a panic, gave her a pill of Riboxin, since there was nothing else. When the ambulance arrived, the grandmother scolded very much, because the drug, in principle, is not intended for children. But, fortunately, the child has not suffered any side effects, but my grandmother was terribly worried).

The therapeutic effects of the drug are not limited only to influences on the myocardium. The active ingredients promote active regeneration of the mucous membrane in destructive diseases of the gastrointestinal tract, and often in the modern world you will meet a person without, at a minimum, a mild form of gastritis. Also, positive effects extend to the blood system, metabolic processes in the kidneys and other organs and systems.

The opinions of doctors only confirm the favorable therapeutic possibilities of the pharmaceutical preparation. Of course, there are also those in the medical community who postulate highly questionable harmful aspects of the use of Riboxin, but the vast majority qualified specialists expresses their "pro" and universally appoints a medicinal product in the fight against various pathological conditions.

Analogues

Structural analogs for the active substance:

Inosie-F;
Inosine;
Inosine-Eskom;
Riboxin bufus;
Riboxin-Vial;
Riboxin-LexT;
Riboxin-Ferein;
Riboxin injection 2%;
Ribonosine.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

Do not exceed the storage temperature of 25 degrees, do not allow children to tablets, the storage location must necessarily be dry and cool. Storage should be carried out for no longer than about 3 years.