Ear drops Normax have antimicrobial effect due to the presence of the modern antibiotic Norfloxacin. This synthetic antibacterial substance, which belongs to the Fluoroquinolones group, has a pronounced bactericidal property.
The mechanism of its action is based on suppression of supercoiling of the DNA of a microorganism due to the blocking of the enzyme DNA-gyrase (it does not affect a similar enzyme in humans).
Ultimately, this leads to a violation of the synthesis of proteins and the death of bacteria.
Clinical and pharmacological group
Antibacterial preparation of the group of fluoroquinolones for topical application in ophthalmology and ENT-practice.
Conditions of leave from pharmacies
It is released on prescription.
Price list
How much are the drops of Normax in pharmacies? The average price is at the level of200 rubles.
Form of issue and composition
Normax is produced in the following forms:
- Eye and ear drops , %: a transparent slightly yellow or colorless solution, free from any particles (5 ml in vials of dark glass with a dropper dropper in a set or in polyethylene bottles-droppers, in a cardboard bundle 1 bottle).
- Film coated tablets: capsular, white or almost white, on one side with a risk (6 or 10 pieces in aluminum foil strips, in a cardboard bundle 1 strip).
Active ingredient: norfloxacin - 400 mg in 1 tablet; 3 mg in 1 ml of drops.
Auxiliary components:
- Eye and ear drops: benzalkonium chloride, sodium chloride, disodium edetate, distilled water, glacial acetic acid.
- Tablets: talc purified, magnesium stearate, silicon dioxide colloid, hydroxypropylmethylcellulose, sodium starch glycolate, titanium dioxide, microcrystalline cellulose, sodium lauryl sulfate.
Pharmacological effect
Ear drops Normaks are often appointed due to the active substance that is included in their composition. The antibiotic of this group destroys DNA of bacteria, contributing to the reduction of the inflammatory process. Has a bactericidal and antibacterial effect.
The drug is highly active against some gram-positive bacteria:
- staphylococci;
- some types of streptococci.
Also Normax has a harmful effect on the following gram-negative bacteria:
- intestinal and hemophilic rods;
- morganella;
- Klebsiella;
- gonococci;
- enterobacteria;
- chlamydia;
- shigella;
- salmonella and others.
Normax helps not only to relieve inflammation, but also to eliminate symptoms such as itching and burning.
Indications for use
Instructions for the use of drops Normax provides for the taking of the drug in the presence of an anamnesis of the following diseases:
- otitis externa;
- acute otitis media or chronic otitis media;
- otitis media;
- infectious form of eustachyte.
As an ophthalmic remedy, Normax is used in diseases:
- conjunctivitis;
- keratitis;
- blepharitis;
- damage to the cornea, both mechanical and ulcerative;
- acute inflammatory processes of the eyes.
The effectiveness of using ear drops to eliminate foci of infection and inflammation of the organs of vision and hearing in the postoperative period was also noted.
Contraindications
Despite the relative safety, this medication, as well as the rest, has some contraindications:
- individual intolerance of the constituent components of the drug;
- pregnancy;
- lactation;
- children under 12 years.
The drug is not absorbed into the blood, therefore, theoretically, it should not harm pregnant and lactating mothers. But in any case, before using, you need to consult with your doctor.
Use in pregnancy and lactation
The drug Normax is not recommended for use in pregnancy. Its use is possible if the risk of complications in the disease exceeds the risk of damage and improper development of the fetus. During breastfeeding, the medicine is also contraindicated.
Dosage and route of administration
In the instructions for use indicated that before instillation in the ear drops Normax should be sanitized external auditory canal.
Drops should have body temperature. The patient should lie sideways or tilt his head to facilitate instillation. After digging in, you need to drop into the ear canal, pulling the earlobe down and back. The head should be kept in this position for approximately 2 minutes. You can put in the outer ear canal wool turunda.
- Assign 1-2 drops to the affected eye or ear 4 times / day. If necessary, on the first day of application, the dose may be increased to 1-2 drops every 2 hours. After the disappearance of the symptoms of the disease, the drug should be continued for the next 48 hours.
In acute and chronic trachoma, 2 drops are prescribed in each eye 2-4 times / day for 1-2 months.
Side effects
It is counter-indicative to combine Normax with physically and chemically unstable drugs. Overdose drops with external application is not possible.
Side effects:
- Digestive system: loss of appetite, nausea, abdominal pain, heartburn, upset of the stool.
- Central nervous system: headaches and dizziness, poor sleep quality, irritability, fast fatigue.
There may be various forms of allergies: skin rash, swelling, itching and burning.
Overdose
There were no reports of cases of Norfloxacin overdose in ophthalmology and otology.
When you accidentally take drops inside you experience nausea, vomiting, diarrhea, headache, dizziness, a sense of anxiety.
Treatment: if necessary, conduct symptomatic therapy; it is necessary to ensure a sufficient supply of fluid in the body, the formation of an acidic urine reaction to prevent crystalluria.
special instructions
Before you start using the drug, read the special instructions:
- Normax is for local use only.
- To achieve a better therapeutic effect, drops should be used in combination with systemic antimicrobial therapy (except for mild cases).
- It is necessary to protect the solution and dropper from contamination.
Within 30 minutes after instillation of the drug in the eye should refrain from engaging in potentially hazardous activities that require increased attention.
Drug Interactions
A solution of norfloxacin is incompatible with drugs having pH 3-4 that are physically or chemically unstable.
Reviews
We picked up some reviews of people who used Normax drops:
- Tatyana. To the son of 16 years, as well as all boys special accuracy does not differ. Forever, if the eye swells, it touches with dirty hands. I recently woke up in the morning, my eyes are red, there are purulent discharge. We were on the same day to see an ophthalmologist. The doctor said that it was conjunctivitis, the bacteria got into the eye. Appointed Normox drops. Drops did not cause unpleasant sensations during application, although they slightly pinch.. But the main thing is that within a few days improvements were already visible! During the week, all the symptoms disappeared.
- Inna. I've been wearing contact lenses for several years now, I only use glasses at home. Sometimes I do not have time to buy new lenses in time, and my eyes immediately react to it and there is redness, and sometimes even a slight suppuration. I used to go to an ophthalmologist, and after she prescribed to me Normaks, I always keep it in my cosmetic bag to immediately bury my eyes. Literally in a short time, all the symptoms disappear.
In general, reviews about ear drops Normax indicate a high efficiency - improvements occur literally after the first use.
Analogues
Structural analogs for the active substance:
- Loxon 400;
- Nolycin;
- Norbaktin;
- Norillet;
- Noroksin;
- Norfacin;
- Norfloxacin;
- Renor;
- Sofazine;
- Chibroxin;
- Utibid.
Before using analogues, consult your doctor.
Storage conditions and shelf life
Regardless of the type of release, it should be stored in a dark place at a temperature of up to 25 ° C. Shelf life of the tablets is 3 years, drops - 2 years, and after opening the bottle - 1 month.
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