Galidor

Halidor is an antispasmodic drug with a pronounced vasodilating pharmacological action.

The main active ingredient is benziclane. When used, its cellular membranes become more resistant to damage. In addition, the drug has vasoconstrictor and antispasmodic effect on the muscular structure of the internal organs.

On this page you will find all information about the Galidor: full instructions for use on this medicated medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Galidor. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Myotropic antispasmodic.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Halidor cost? The average price in pharmacies is at the level of650 rubles.

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Form of issue and composition

Halidor is available in two dosage forms - a solution for parenteral administration (intramuscularly or intravenously) and tablets. The solution contains the main active substance of the drug bacciclan fumarate in an amount of 25 and 50 mg in 1 ampoule.

The solution of Halidor is contained in glass ampoules of 2 ml, which are packaged in a contiguous cell pack of 10 pieces. The cardboard pack contains 1 or 5 contour mesh packages with an appropriate number of ampoules and instruction on the use of the preparation.

Pharmacological effect

Myotropic antispasmodic with pronounced vasodilating effect. The vasodilator effect of benzyclane is mainly due to its ability to block calcium channels, antiserotonin action, and to a lesser extent - with blockade of sympathetic ganglia. Benzyclane can cause a dose-dependent suppression of Na + / K + -dependent ATPase and platelet and erythrocyte aggregation, as well as increased erythrocyte elasticity. These effects are observed mainly in peripheral vessels, coronary arteries and cerebral vessels.

In addition, benzyclan has an antispasmodic effect on the visceral musculature (GI tract, urinary tract, respiratory system). The drug causes a slight increase in heart rate. It is also known for its weak tranquilizing effect.

Indications for use

Indications for the use of Galidor are vascular diseases:

1. Disorders of cerebral circulation: complex treatment of chronic and acute cerebral ischemia.
2. Violations of the functions of peripheral vessels: Raynaud's syndrome and other diseases with spasm of blood vessels and acrocyanosis, chronic obliterating diseases of the arteries.

Also, Halidor is prescribed to eliminate spasm of internal organs:

1. Urologic syndromes: tenesmus and spasms of the bladder, ancillary treatment of urolithiasis (together with analgesic drugs for renal colic).
2. Gastrointestinal diseases: inflammatory and infectious colitis, tenesmus, gastroenteritis of various origin, functional diseases of the large intestine, cholecystitis, postoperative flatulence, condition after surgical removal of the gallbladder, cholelithiasis, duodenal ulcer, or stomach (in combination therapy with other medicinal means).

An additional indication for the use of Galidor in the form of a solution for injections is the preparation for cystoscopy, retrograde pyelography, cystography, urethrography and intravenous urography.

Contraindications

Application in pregnancy and lactation

Pre-clinical data showed no embryotoxic or teratogenic effects.

Despite the absence of embryotoxic effects in the widespread use of the drug, its administration to patients in the first trimester of pregnancy is not recommended. In the absence of reliable data obtained in a human study, the use of this drug during breastfeeding requires careful analysis.

Instructions for use

The instructions for use indicate that Halidor in the form of tablets should be taken orally. In the form of a solution - in the form of IV injections or infusions and deep intravenous injections.

Dosage for the removal of spasm of internal organs:

• Inside, Halidor is prescribed in a dose of 100-200 mg once, but not more than 400 mg / day. For maintenance therapy appoint 100 mg 3 times / day for 3-4 weeks, then 100 mg 2 times / day. The duration of treatment is determined individually, depending on the disappearance of the symptoms of the disease and, as a rule, does not exceed 1-2 months.
• In acute cases, Halidor is administered IV slowly in a dose of 100-200 mg (4-8 ml) or in / m deep in a dose of 50 mg (2 ml). Before / in the introduction of the required amount of solution is diluted with an isotonic sodium chloride solution to 10-20 ml. The course of treatment is 2-3 weeks with the subsequent transfer of the patient, if necessary, to take the drug Galidor inside.

Recommended dosing in the treatment of vascular diseases:

• Inside, Halidor is prescribed 100 mg 3 times / day for 2-3 months. The maximum daily intake for oral administration is 400 mg. The interval between courses is 2-3 months.
• The drug can also be used in the form of intravenous infusions in a daily dose of 200 mg divided into 2 injections. Before the infusion, 100 mg (4 ml) of the drug is diluted in 100-200 ml of isotonic sodium chloride solution and injected / drip for 1 hour 2 times / day.

The doctor appoints the course of treatment and dosage form of the drug individually, taking into account the clinical indications and the patient's condition.

Side effects

Overdose

Overdose can cause more heartbeat, lower blood pressure, predisposition to collapse, urinary incontinence, drowsiness, anxiety, and in severe cases - epileptiform convulsive seizures.

Treatment of an overdose: A specific antidote is not known. In case of an overdose, wash the stomach and take symptomatic treatment. To treat convulsive seizures, it is recommended to use benzodiazepines. Data on the possible excretion of bcyclical by dialysis are not available.

special instructions

Use of the drug for use in the form of injections requires a change in the site of administration, since there is a risk of drug damage to the integrity of the vascular endothelium. When using Galidor with drugs that can cause hypokalemia, oppression function of the myocardium or the intake of cardiac glycosides, it is necessary to reduce its dose per day to 150-200 mg.

It is not recommended to administer the drug in injectable form to patients suffering from:

• a delay in urine;
• hypertrophy of the prostate;
• having a propensity to collapse;
• cardiovascular insufficiency in severe form;
• respiratory failure in severe form.

Long-term use of Galidor should be accompanied by regular blood tests (every 2 months). People associated with the implementation of hazardous work and transport drivers should be careful when using Halidor at the beginning of treatment.

The medicine is able to strengthen the action of sedatives and preparations for general anesthesia. Care should be taken to apply them simultaneously.

Drug Interactions

In appointing Halidor simultaneously with cardiac glycosides, drugs that cause hypokalemia or suppressing the function of the myocardium, the daily dose of the drug should be in the range 150-200 mg.

Reviews

We picked up some of the people's opinions about the preparation of Halidor:

1. Olga. Mom 89 years old, legs hurt. The surgeon has registered a halidor. The first day everything was fine. And by the evening of the second day, my hands began to shake, my head ached, and my head began to feel dizzy, I began to feel sick, my legs were wadded, and practically stopped walking. We called an ambulance - the doctor said that we need to replace the drug. The surgeon was wildly surprised at such consequences. He said that maybe these are signs of a disorder of the cerebral circulation. And this can lead to a stroke. Plus in the annotation we read that the drug is not recommended for traumatic brain injury.
2. Margarita. Always boldly started taking medicine, tk. usually well tolerated. But not at this time! Took days 8 and already the third day as canceled. The condition after cancellation has not improved, periodically nausea, rolls on walking, the noise in the ears becomes much more intense, it really hinders. Now I realized that I had not been sick before. An anesthetic pill every 7-10 days already suits me in comparison with my current state. By the way, the next attack of a headache I missed)).
3. Inna. I learned about Halidore for a long time, but my experience is connected with its intolerance (maybe because it extends the vessels too well). I was prescribed it to improve cerebral circulation and dilute blood. There were side effects (headache, frequent palpitations, dizziness). Although many helped well and they easily tolerated it. In general, I gave my Galidor to my grandmother (her cerebral circulation is disturbed).

The doctors' comments about Halidor agree that the drug is strong enough and it is very important not to forget when applying it about caution, especially the elderly and people prone to allergies. Reviews on the forums also confirm a high probability of side effects in people prone to it.

Analogues

As analogs, it is possible to use Benzyclane, Benzyclan Fumarate, Vinoxin MB, Dibasol, Dibazol-Darnitsa, Duzopharm and Enelbin 100 Retard.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Keep out of reach of children at temperatures between 15 ° and 25 ° C. Shelf life of the tablets is 5 years. Shelf life of the injection solution is 3 years.

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