Maxitrol Eye Drops

Maxitrol drops for eyes - an ophthalmic combined drug.

It includes 2 antibiotics and a glucocorticosteroid. Maxitrol has anti-inflammatory, antibacterial and antiallergic effect.

The bactericidal advantage of the drug is staphylococcus aureus (Staphylococcus aureus), streptococcal infection (Streptococcus viridans), diphtheria pathogens (Corynebacterium diphteriae), conjunctivitis pathogens (Koch-Weeks bacillus), intestinal rod (Escherichia coli), Proteus (Proteus vulgaris), Klebsiella pneumoniae), Haemophilus influenzae, enterobacteria (Aerobacter aerogenes), Pseudomonas aeruginosa (Pseudomonas aeruginosa).

Clinical and pharmacological group

The drug with antibacterial and anti-inflammatory action for topical application in ophthalmology.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much is Maxitrol? The average price in pharmacies is at the level of500 rubles.

Form of issue and composition

Maxitrol is available in the form of eye drops: an opaque suspension from white to pale yellow 5 ml in bottles of low-density polyethylene with dropper Drop-Teiner, in a pack of cardboard 1 bottle).

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Active substances in 1 ml of drops:

Dexamethasone - 1 mg;
Polymyxin B sulfate - 6000 ED;
Neomycin sulfate - 3500 units.

Additional components: sodium chloride, benzalkonium chloride solution, equivalent to benzalkonium chloride, polysorbate 20, hydroxypropylmethylcellulose, purified water, hydrochloric acid, concentrated and / or sodium hydroxide (before adjusting the pH).

Pharmacological effect

The main active substances Maxytrol eye drops are antibiotics (neomycin, polymyxin B) and corticosteroid (dexamethasone). Such a combination provides a wide range of effects of the drug, as follows:

Polymyxin B (3500 EM), a cyclic polypeptide actively destroys streptococci, Pseudomonas aeruginosa, klebsiella, salmonella, shigella, hemophilic rod (neomycin has a weak effect on them).
Neomycin (6000 EM), 4th generation aminoglycoside, provides bactericidal action on a wide range of bacteria: pneumococci, staphylococci, intestinal and dysentery bacillus, proteins, etc.
Dexamethasone (1 mg), glucocorticosteroid penetrates into the cells of the eye structures, where it reduces the permeability of cell membranes, blocks the release of histamines, strengthens the vessels of small capillaries.

The main active ingredients are supplemented with hypromellose, saline, polysorbate, distilled water, as well as antiseptic benzalkonium chloride.

When the drug is used, the bacterial infection is actively destroyed, the cornea and mucosal edema are quickly eliminated, the lacrimation is normalized. The drug well removes inflammation, reddening of the sclera and itching caused by allergic reactions and infection. Relief comes almost immediately after instillation, drops do not cause burning in the eye.

However, antibiotics do not affect intracellular infections (viruses), including they are powerless against herpes simplex virus, the drug against mycosis (fungal) lesions, purulent inflammations is inactive.

Indications for use

As mentioned above, Maxitrol is used to relieve inflammation of the eyes. Shown in the following cases:

Keratitis;
Iridocyclitis;
Bacterial inflammation of the eyelids (blepharitis);
Infection of the eye mucosa (conjunctivitis);
Chemical agents on the mucous eyes, burns or mechanical damage;
Preventive measures after surgical intervention to prevent possible complications.

Contraindications

Drops have contraindications to use:

Individual hypersensitivity.
Viral, tuberculosis and fungal lesions of the eyes.
Purulent lesions of the cornea.
Pregnancy, lactation.
Childhood.

Maxitrol can be prescribed with caution to patients with cataract and glaucoma.

The safety and efficacy of Maxitrol in pediatrics have not been established.

Use in pregnancy and lactation

Sufficient experience in the use of the drug during pregnancy and lactation is not present. It is possible to use the treatment for pregnant women on prescription of the attending physician if the expected curative effect exceeds the risk of development of possible side effects.

It is necessary to interrupt the use of the drug for the period of breastfeeding.

Dosage and route of administration

In the instructions for use it is indicated that eye drops Maxitrol are applied topically.

With a mild infectious process, 1-2 drops in the conjunctival sac 4-6 times / day.
In acute severe infectious process, 1-2 drops in the conjunctival sac every 60 minutes with a decrease in the frequency of instillations of the drug as the phenomena of inflammation decrease.

Side effects

In some cases, the use of Maxitrol can provoke thinning of the cornea, which as a result may cause the development of its perforation. Sufficiently prolonged use of drops in some cases can cause side effects in the form of intraocular pressure, as well as provoke the development of cataracts.

With topical application, allergic reactions of various origins are possible, including itching, eyelid swelling and conjunctival hyperemia. When using the drug for more than 10 days, it is recommended to monitor intraocular pressure.

Overdose

At the moment there are no recorded cases of overdose with topical application.

special instructions

The bottle must be closed after each use. Shake the bottle before use.

For long-term treatment (more than 10 days), monitor intraocular pressure.

Drug Interactions

Interaction with other drugs is not currently known.

In case of use with other local ophthalmic preparations, the interval between their use should be at least 10 minutes.

Reviews

Reviews of eye drops are few, since the drug is released in pharmacies only on prescription, but those who applied Maxitrol notes that it helps, does not burn eyes and does not cause other side and allergic reactions.