Nemosol

Nemosol is a highly effective anthelmintic preparation.

The main mechanism of action is associated with the inhibitory effect on the polymerization of beta-tubulin, which leads to the destruction of cytoplasmic microtubules of cells of the intestinal tract of helminths, alters the course of biochemical processes (suppressing the utilization of glucose), blocks the movement of secretory granules and other organelles in the muscle cells of roundworms, causing their death.

Nemozol is the most active in its reviews of larval forms of cestodes Taenia solium and Echinococcus granulosus, and Strongyloides stercolatis nematodes.

Clinical and pharmacological group

Anthelmintic preparation.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Nemosol cost in pharmacies? The average price is at the level of225 rubles.

Form of issue and composition

The anthelminthic agent Nemozol is available in the following dosage forms:

Chewable tablets Nemozol - oval, capsular form, white, with a risk on one side. Each tablet contains 400 mg of albendazole + auxiliary components. In a cardboard bundle with the drug is a blister with 1 chewing tablet Nemozola.
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Suspension Nemozol - is a homogeneous white substance with a fruity aroma. In 5 ml of the suspension (1 scoop) is 100 mg of the active substance albendazole + auxiliary components. The suspension is released in 20 ml plastic bottles. Nemosol is preferred for children in the form of a suspension.
Tablets Nemozol in a film shell - round, biconcave, white. Produced in 2 versions with different concentrations of active substance: 200 mg and 400 mg. In addition to albendazole, the formulation includes auxiliary components (sodium lauryl sulfate, starch, talc, povidone, gelatin, etc.). Tablets of 1 or 2 pieces are packaged in blisters and packaged in cardboard packs.

Various forms of release are one of the advantages of an anthelmintic agent. For children, the drug is produced in the form of a suspension with a pleasant taste, which does not cause them to reject. Adults also have a choice. If they do not like to swallow ordinary tablets, you can buy a chewing form of the drug with a pleasant taste and pineapple or mint flavor.

Pharmacological effect

The albendazole (Albendazole) contained in Nemosol is a potent antiparasitic agent with a broad spectrum of action.

The main mechanism of action of the substance is related to its ability to suppress the polymerization of the beta-tubulin protein. This leads to the fact that in the cells of the intestinal tract of helminths the activity of the cytoplasmic microtubule system is disturbed; the flow biochemical processes in parasitic organisms; in the muscle cells of nematodes, the movement of secretory granules and other organelles is blocked. The result of such an impact is the death of parasites.

The most effective against larvae of tapeworms (pork chain and echinococcus), as well as against roundworms Strongyloides stercolatis (intestinal ugly).

Indications for use

Treatment with Nemosol is recommended for:

mixed helminthic invasions;
strongyloidiasis;
giardiasis;
toxocarose;
nematodosis - non-catarrhoea, enterobiasis, ankylostomiasis, ascariasis, trichocephalosis;
neurocysticercosis, caused by the larval form of Taenia solium;
echinococcosis of the lungs, peritoneum and liver, caused by the larval form of Echinococcus granulosus.

Nemozol is recommended to be used as an aid in the surgical treatment of echinococcus cysts.

Contraindications

Absolute:

Defeat of the retina;
Pregnancy;
Hypersensitivity to the drug or other benzimidazole derivatives.

Relative (care should be taken in connection with the existing risk of complications):

Dysfunction of the liver;
Violation of hematopoiesis;
Lactation.

Use in pregnancy and lactation

In pregnancy / lactation, the use of albendazole is contraindicated. If it is necessary to prescribe the drug to lactating women, breastfeeding should be discontinued.

To prevent the use of Nemosol in early pregnancy, women of childbearing age should be treated only after excluding the fact of pregnancy.

During the use of the suspension / tablets, reliable contraception should be provided.

Dosage and route of administration

The instructions for use indicate that Nemosol is taken while eating. It is recommended that all members of the family be treated at the same time.

The average therapeutic dose for the treatment of nematodes for adults and children over 2 years is 400 mg or 20 ml of the suspension orally once.

For children with gambliasis, the drug is prescribed at a rate of 10-15 mg / kg 1 time / day for 5-7 days.
With neurocysticercosis and echinococcosis, patients with a body weight of 60 kg or more are prescribed 400 mg twice daily; with a body weight of less than 60 kg, the dose is set at a rate of 15 mg / kg / day in 2 divided doses. The maximum daily dose is 800 mg (400 mg 2 times / day). The course of treatment for neurocysticercosis - 8-30 days; with echinococcosis - 3 cycles of 28 days with a 14-day interval between cycles.
With toxocarosis, adults and children over 14 years of age with a body weight of more than 60 kg are prescribed 400 mg 2 times / day; with mass body less than 60 kg - 200 mg 2 times / day; Children under 14 years of age are given a dose of 10 mg / kg 2 times / day. Duration of therapy is 7-14 days.

Reviews of Nemosol for children and adults indicate that parasites after taking the drug come out usually within a week. After 3 weeks after the treatment, it is recommended to do a second analysis of the stool.

Side effects

According to the reviews, in most cases, Nemozol is well tolerated by children and adults. Sometimes when taking the drug there are violations of the digestive system, manifested as nausea, pain in the abdomen, vomiting.

Also Nemozol according to reviews can contribute to violations of other vital systems of the body in the form of:

Dermatological reactions: itching, skin rash, reversible alopecia;
Central nervous system: dizziness, headache, meningeal symptoms;
The system of hematopoiesis: agranulocytosis, pancytopenia, leukopenia, thrombocytopenia, granulocytopenia;
Digestive system: nausea, vomiting, abdominal pain, impaired liver function (moderate or weak increase in transaminase activity);
Other: increased blood pressure, allergic reactions, fever, acute renal failure.

Overdose

By accidentally ingesting a large number of tablets in the patient, there is an increase in the side effects described above, a change in blood pressure indicators, a violation of liver function.

If signs of overdose develop, the stomach should be washed to the patient and the activated charcoal or any other sorbent should be taken. If necessary, symptomatic treatment is performed.

special instructions

Against the background of the use of the drug, it is recommended to control the cellular composition of the blood. When leukopenia occurs, the therapy is suspended.

Blood tests should be performed at the beginning of each 28-day cycle every 2 weeks during the therapy with albendazole. Continue treatment with albendazole is possible if a decrease in the total content of leukocytes and neutrophilic leukocytes is moderate and does not progress.

With neurocysticercosis, appropriate SCS therapy and anticonvulsants should be given. GCS for oral or intravenous administration is used to prevent hypertensive attack in the first week of anti-cystic therapy.

Drug Interactions

When combined with albendazole, dexamethasone and cimetidine increase the concentration of albendazole sulfoxide in the blood.

Reviews

We picked up some reviews of people who used the drug Nemozol:

Rita. To the child 3 years, in a feces eggs ascaris. The suspension was given on the advice of doctors nemozol 3 times with interruptions in 3-4 weeks - 250 mg, 400, 400 (the entire vial, adult dose). It did not help, nothing happened, in the analysis there were eggs every time. In vain we poisoned the child.
Tatyana. Faced worms in the child, when they started going to the kindergarten. The doctor advised Nemozol. Immediately I found it in the pharmacy. Acted strictly according to the instructions. After the course of treatment, we forgot about these worms.
Julia. Collided with Nemosol a couple of months ago. The youngest son began to cry and on the priest to show painfully speaks, looked, and there!!! The evening was late, and the child wanted to help, called a familiar pharmacist, she offered three drugs to choose from. Among them was Nemozol. We went to the pharmacy and took a suspension, as a little pill spits! During dinner, I gave one teaspoon, about 20 grams. Nemozol tastes good, and most importantly, not bitter. The itch, of course, went through about half an hour, but the next day in the stool of bjaka was! According to the instructions five days later she gave me a teaspoon during the meal, and everything, after that, was not there!

Analogues

Structural analogues of the active substance are such anthelmintic agents as Helmodol, Albendazole and Sanoxal. Among other medicines with an identical therapeutic effect, one can name: