Midsummer: what helps? instructions for use

Midokalm tablets: indications, instructions for use, reviews

Among the drugs that are used for therapeutic therapy of osteochondrosis and many neuralgic diseases is its deserved popularity received Midokalm, as the drug has not only painkillers and miorelaksiruyuschee, as well as anti-inflammatory impact.

Midokalm - an effective muscle relaxant, relaxing muscles by reducing the pathological signaling of the nervous system. In addition, it is able to dilate blood vessels and relieve muscle spasm.

This is a highly effective and safe remedy for the treatment of neurological syndromes, which are associated with pain, muscle tone and trophism disorders.

The active substance of Midokalma has a membrane-stabilizing and local anesthetic effect. The drug reduces musculoskeletal tension, spasticity and causes an indirect analgesic effect, as well as dilates blood vessels and improves circulation of blood and lymph.

The composition of

The composition of the drug includes the following elements:

• active elementcontained in one tablet in the amount of fifty or one hundred and fifty milligrams - tolperisone hydrochloride;
• to auxiliary substancesinclude: citric acid monohydrate, oxygen dioxide silicon, stearin acid, talc, cellulose in microcrystalline form, corn starch, lactose monohydrate.
• Also, apart from the tablet itself, it is placedin a shellfor better passage through the digestive system, which includes: oxygen dioxide silicon dioxide, titanium dioxide, lactose monohydrate, macromol, hypromellose.

Pharmacological profile

Midokalm is the central muscle relaxant (a drug that causes a weakening of the tension of the striated muscles).

The active ingredient is tolperisone hydrochloride, which causes the primary membrane-stabilizing influence preventing excitation in afferent neurons and blocking motor spinal reflexes. The mechanism of the secondary action of the drug consists in reducing the reflex availability of the spinal cord in the reticulospinal tract.

Midokalm enhances the circulation of peripheral blood. This effect is due to the insignificant spasmolytic effect of tolperisone and its ability to reduce the excitability of the adreno-reactive system.

The process of assimilation and metabolism of components of preparations of tolperisone hydrochloride occurs in the liver, and then the substance is excreted by the kidneys as intermediate products of the metabolic process (metabolites).

But, it should be taken into account that the pharmacological features are not fully understood to this day.

After taking the medication and getting it into the body, the pain threshold and unpleasant sensations in the muscles decrease. The drug has a calming and anti-inflammatory effect.

This therapeutic effect can increase the effectiveness of other medications and it is for this reason that Miodocalm is often used in complex therapy.

Also, when taking this medicine, doctors prescribe medical massage and gymnastics for the quickest removal of muscle tension.

Indications for use of Midokalma

What helps Midokalm in tablets:

• to remove the increased muscle tone, which it takes after long and intensive physical exercises;
• for the treatment of diseases of the musculoskeletal system, in which the muscle tone increases and spasms increase;
• inflammatory processes caused by osteochondrosis;
• increased pain syndrome with inflammation of hemorrhoids (hemorrhoids);
• Neuralgic diseases that increase muscle tone;
• to remove spasticity in neurological disorders.

Contraindications to prescription

It is contraindicated for taking medications in the following situations:

• if, the patient has an allergic reaction to one of the components that is part of the drug (before using it is recommended to make allergic tests);
• during complex therapy with vascular lesions, as well as in pathologies and other chronic diseases that were caused by a violation of the vascular functionality.

Instructions for use - dosage

According to the instructions given by the manufacturer, the Meadocals tablets should be taken after a meal (15-20 minutes after a meal), washed down with a small amount of liquid.

This drug can be taken to children from the age of three. The daily dose for a child from 3 to 7 years is prescribed from the calculation: 5 mg of the drug per 1 kg of weight, at the age of 7 to 14 years - 3 mg / kg. The received dosage is divided into three parts and taken inside during the day.

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Dosage for adults and children from 14 years of age at the beginning of the course of treatment is 100 mg per day (50 mg for two meals). The daily dose gradually increases to 150 mg.

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But the final dosage is determined only by the attending physician, relying on the following data obtained during the examination and after the tests:

• intensity of clinical symptoms;
• degree of increase in muscle tone and manifestations of pain syndrome;
• presence of concomitant diseases in the patient.

The course of treatment with this drug, which is prescribed for osteochondrosis and other chronic diseases lasts from 7 to 10 days.

Also, the patient should remember that self-medication is categorically contraindicated!

To date, there is no evidence of an overdose of Miodocalm, since active substance, which is part of the drug, to study the complete clinical picture is impossible. But, according to the latest data received, Midokalm specialists are characterized as a non-toxic drug that has a wide range of therapeutic effects on the body.

The drug does not have a specific antidote. If the recommended dose is exceeded and any unwanted symptoms, the patient is recommended to wash the stomach and then - symptomatic and supportive therapy.

Possible side effects when taking Medocalsum:

• sudden temperature increase, general malaise, nausea and vomiting;
• a headache that can develop into a migraine;
• muscle aches and spasms.

According to the statistics, Midokalm rarely causes any side effects. But when they manifest, it is recommended to immediately consult a doctor and gradually stop treatment, reducing dosage.

Special instructions and advice

The tandem of alcohol and Midokalma is acceptable, since such interaction is not prohibited by the instruction for use.

Due to the fact that the composition of the drug to a greater extent includes natural substances, its administration in violation of the functions of the kidneys and the liver is permissible.

Interaction with other drugs is allowed, since this drug is often used in the complex therapy of many diseases.

It is important to know: moreover, Midokalm is prescribed during pregnancy to increase the tone of the muscles of the uterus.

Admission Midokalma in childhood is allowed, since it includes only natural means that do not harm the child's body.

But, parents should remember that taking this medication by children is allowed only from the age of five.

Practical experience of application

Reviews of doctors and patients who drank the course of Miodocalma in tablets.

Midokalm represents a drug that can cope with muscle pain in osteochondrosis and neuralgic diseases. From its main advantages it is necessary to allocate the natural components that make up the composition.

Regarding the dosage, it should be taken into account that the main thing is to choose the optimal dosing and registration tactics with other drugs, because only this way you can achieve maximum effectiveness.

Anastasia S., 42 years old, neurologist

With neuralgic muscle hypertension, my child was prescribed Midokalm, as he relieves muscle spasm and pain.

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I decided to write my review because there are very few reviews on the Internet about taking this medicine by children.

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It would be desirable to notice, that we accepted a medicine without special fear, as it possesses natural structures.

After the treatment course, spasms and pains became fewer times.

Karina, 30 years old

A few years ago, I was faced with such a problem as osteochondrosis, echoes of which haunts me to this day and for That there was no chronic exacerbation, I take Midokalm, the course of treatment which I have for 2 years of life without pain and discomfort.

Karina, 27 years old

Together with a bunch of other medicines for neuralgia, the neurologist appointed Meadolph. At first everything went smoothly, but after a week, side effects started (tinnitus, nausea, pain in the liver). So, the course of treatment was terminated.

Having studied the forums on which patients leave their responses about this or that medicine, it can be concluded that the majority patients recommend taking Midokalm in a complex therapy, as with a separate admission, it causes a general malaise and nausea.

Pros and cons of medicine

Benefits:

• the natural composition of the drug;
• wide range of applications;
• a small number of contraindications;
• not pronounced side effects, which is very rare and in exceptional cases.

Disadvantages: side effects, which are characterized by an allergic reaction with intolerance to the components of the drug.

Purchase and storage

The price of Meadokalm tablets is 300 rubles. Keep the medication recommended in an enclosed space, out of reach of children at a temperature of 10 to 25 degrees Celsius.

The drug is dispensed in a pharmacy without a prescription.

Read More

A source: http://neurodoc.ru/lekarstva/tabletki-midokalm.html

"Midokalm what helps, the description of the drug, contraindications

What is the medicine Medogalm? What helps this tool? Indications and features of the medication in question will be presented below. Also you will learn how to treat this drug, how much it costs and what its composition is.

Pharmaceutical form, package, description, composition

In what form does the medication "Midokalm" come in (what helps this medicine, we will tell below)? This product is available in tablets, as well as in a solution intended for parenteral administration.

Round and white tablets "Midokalm the price of which is indicated below, consist of tolperisone hydrochloride.

As additional ingredients in the composition of the drug in question are: anhydrous colloidal silicone, citric acid monohydrate, starch corn, stearin, hydroxypropylmethylcellulose 2910, talc, macrogol 6000, microcrystalline cellulose, dye, lactose monohydrate and dioxide titanium.

This product is produced in blisters, which are placed in boxes of paper.

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The clear solution of "Midokalm" in ampoules also contains tolperisone hydrochloride and lidocaine.

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In addition, this medicine includes the following constituents: talc, citric acid monohydrate, lactose monohydrate, colloidal anhydrous silicone, macrogol 6000, microcrystalline cellulose, stearin, titanium dioxide, corn starch, black iron oxide, hydroxypropyl methylcellulose 2910, red iron oxide and yellow iron oxide.

The drug "Midokalm" in ampoules is contained in plastic containers, which are placed in boxes made of cardboard.

Basic properties

What is "Midokalm"? What helps with this drug? According to the instructions, the agent in question refers to the muscle relaxants of the aminoketone group, which has a central effect.

The effectiveness of this drug is associated with the regulation of the operation of a part (caudal) of the reticular formation. The use of this medication contributes to the suppression of increased reflex excitability of the spinal cord. It also affects the nerve endings (peripheral).

Features of the medicine

The drug "Midokalm" (compatibility of this drug with others is permissible, but under special conditions) is an H-anticholinergic.

Its active substance has a stabilizing effect on membranes in primary fibers (afferent), as well as motor neurons.

It should also be noted that this drug again slows the excretion of mediators. This is due to inhibition of the process of calcium intake into the synaptic structures that are in the nerve fibers.

The effect of this agent on the reticulospinal path is particularly pronounced when the excitation processes slow down. Similarly, local anesthetic action of the drug is revealed (due to the content of lidocaine in it).

Medication kinetics

The agent is well absorbed from the intestine. Its concentration (maximum) in the blood is reached 65 minutes after admission. Metabolism of the drug occurs in the kidney and liver. Derivatives of tolperisone are excreted together with urine.

The repeated course of "Midokalma" has no effect on the work of the kidneys and liver, as well as on the process of hematopoiesis.

This remedy reduces the experimentally induced rigidity and hypertonicity of muscle tissue. The therapeutic properties of this drug are actively used to reduce the rigidity of muscles and pathological hypertonia, which is associated with extrapyramidal disorders.

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It should also be noted that this drug contributes to the activity of a person (his movements). In addition, it has no effect on the cerebral cortex, fully preserving the level of wakefulness of the patient.

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According to the instructions, treatment with "Midokalm" causes slightly expressed spasmolytic and adrenoblocking effects. Thanks to this, tissue perfusion improves.

In the process of conducting long-term clinical studies, this tool did not have a significant effect on hematopoiesis and kidney function.

The drug "Midokalm from what helps?

This tool is indicated for use in the following cases:

• In pediatric practice with the aim of treating Little's disease (ie spastic paralysis). In addition, this drug is used with encephalopathy of another origin with the phenomena of muscular dystonia.
• In conditions that are accompanied by pathological hypertension of striated muscle tissue developing due to pathologies (neurological) organic origin (for example, with multiple sclerosis, encephalomyelitis, myelopathy, residual phenomena of acute disorders of cerebral circulation, lesions of pyramidal paths).
• In conditions that have arisen as a result of damage to the innervation of blood vessels (for example, in acrocyanosis, angioedema, intermittent nature).
• With muscle hypertension, contracture of the muscles that accompany diseases of the organs of motion (for example, spondylosis, elbow, knee and hip joint arthrosis, spondylarthrosis, lumbar and lumbar syndromes cervical).
• With postthrombotic disorders of venous blood flow and lymphodynamics.
• As a restorative postoperative treatment in orthopedic and traumatological practice.
• With trophic ulcers formed on the lower extremities, angiopathy (including diabetogenic), obliterating angiosclerosis and thromboangiitis, as well as autoimmune diseases (with Raynaud's disease and systemic scleroderma).

Prohibitions to use

In what cases, can not be prescribed pills and injections of "Midokalm"? The use of this medication is contraindicated when:

• myasthenia gravis;
• hypersensitivity to tolperisone and a known allergy to lidocaine;
• at the age of up to three months (in tablet form up to one year).

Mode of application

The scheme of application of this drug is determined by the doctor depending on the course of the disease, as well as the tolerability of the drug.

For adults, the medication is prescribed in an amount of 150-450 mg (daily dose) in three divided doses. The starting dosage of this medication is 50 mg three times a day. With insufficient efficiency, it is increased.

For intramuscular injections the drug is used in an amount of 200 mg per day (in two administrations), and intravenous - 100 mg (once a day). In the second case, a very slow infusion of the drug is required.

For children older than three months (up to 6 years), the dosage of the medicament is calculated according to the following scheme: 5-10 mg per kg of body weight (three times a day). For a child 7-14 years of age, it is recommended to use tablets in a daily dose of 2-4 mg per kg of body (three times a day).

Oral reception "Midokalma" must be combined with eating.

Side effects

Taking the drug with individual hypersensitivity can cause weakness in the muscles, dyspeptic symptoms (nausea, discomfort and vomiting), as well as headaches.

With a rapid intravenous infusion of the solution, a decrease in blood pressure is possible.

With an individual drug intolerance, allergic reactions develop. As a rule, with a decrease in the dose of the drug, side effects occur very quickly.

Drug Interactions

Information on the interaction, which limits the use of the drug in question, is not available.

However, it should be noted that tolperisone has an effect on the central nervous system.

This drug does not cause drowsiness, so it can be combined with hypnotics and sedatives, as well as medications containing ethanol.

Peripheral muscle relaxants, preparations for general anesthesia and psychotropic drugs, as well as "Clonidine" enhance the efficacy of tolperisone.

Cost and reviews

How much does "Midokalm" cost? The price of this facility is about 185 rubles.

The patients' reviews say that the medication in question is very effective, especially with joint diseases. In addition, this remedy is a good remedy for impaired blood circulation in the brain, including those that occurred after traumatic brain injury.

Among the negative reviews can be identified those in which it is said that the drug "Midokalm" is not a panacea. Most often this medicine is used as a supportive treatment.

A source: http://.ru/article/242060/midokalm-ot-chego-pomogaet-opisanie-preparata-protivopokazaniya

Medikalm Medication from what helps

Midokalm, from what helps? Effective drug, which helps to relax the increased tone of skeletal muscles in neurological syndromes, including arthrosis and osteochondrosis.

Form of issue

They release the medicine Midokalm in the form of a round biconvex form of tablets coated with a film membrane. On one side, each tablet has an engraving "50" or "150" (depending on the amount of active substance in it).

The color of the tablets is white or almost white (even on the break), the smell is mild, specific.

pharmachologic effect

Medokalm (from which it helps from many ailments) is a highly effective and safe remedy for treatment of neurologic syndromes, which are associated with pain, muscle tone and impaired trophies. The active substance of Midokalma has a membrane-stabilizing and local anesthetic effect.

The drug reduces musculoskeletal tension and causes an indirect analgesic effect, as well as dilates blood vessels and improves the circulation of blood and lymph. According to the reviews, Miodocal is fast acting and well tolerated.

The drug Midokalm from what helps

Indications for the appointment of a medicament are:

• threat of spontaneous interruptionof pregnancydue to an increase in the tone of uterine muscle structures;
• pathologically increased muscle tone and spasms of skeletal (transverse-striated) muscle tissue, which are the consequence of organic lesionsCNS, including includingmultiple sclerosis, encephalomyelitis, strokebrain, etc .;
• pronouncedpain syndrome, marked on the background of developmenthemorrhoids;
• myogenic contractures, increased tonus and spasticity of muscles due to diseases of the musculoskeletal system (for example,lyubmago with sciatica, spondylosis, affecting large jointsarthrosis,cervical syndromeetc.);
• non-inflammatory diseases of the brain, accompanied by disorders of muscle tone (for example,infantile cerebral palsy);
• cholelithiasis;
• menstrual pain syndrome;
• renal colic.

Application of the drug Midokalm is shown:

• in the period of reconstructive therapy after orthopedic, surgical or traumatological operations (this is due to the abilityTolperisonehave a beneficial effect on the degree of stretchingmuscle fibers);
• for symptomatic treatmentmuscular spasmin adult patients who have hadstroke;
• as part of complex therapy for obliterating lesionsvessels(according to the annotation, the remedy is effective atdiabetic angiopathy, Raynaud's syndrome, obliterating thrombangiitisetc.);
• at pathologies caused by disorders of innervationvessels(gross abnormalities of the gait or pathological cyanosis of the limbs).

The dose of Midokalma is prescribed individually according to the instructions, depending on the tolerability of the drug and the clinical picture. Tablets Midokalm (from which they help better) are taken after a meal. Usually adults take up to three times a day for 1 tablet (50 mg). If necessary, the dose can be increased three-fold, taking 3 tablets of Miodocalma three times a day. For children, the use of Miodocalm in the form of tablets of 50 mg is allowed. The daily dose of Midokalma is taken in three steps:

• 1-6 years - calculating the daily dose, 5 mg per 1 kg of weight;
• 7-14 years - 2-4 mg per 1 kg of weight.

If it's impossible to swallow the Midokalma tablet, it can be rubbed.

When applying injections, Miodocalm is administered:

• Intramuscularly - 200 mg per day, divided into two doses;
• Intravenously, the drug is administered slowly, once a day for 100 mg.

There are no data limiting the use of Miodocalm with other medications. The drug can be used simultaneously with sedatives, hypnotics and drugs containing ethanol.

However, it should be borne in mind that Midocalm strengthens the action of niflumic acid.

Use Midokalm during pregnancy, especially in the first trimester, as well as during lactation can only by strict indications.

Contraindications Meadokalm

From what does not help, but it harms:

• age up to one year;
• persistent pathological weakness and rapid fatigue of skeletal muscle tissue (myasthenia gravis);
• increased individual sensitivity to any of the components of the drug.

Before taking Miodocalmosteochondrosis, it should also be noted that all muscle relaxants are contraindicated in patients:

• who have, at present or in the anamnesis, increased convulsive activity;
• suffering from Parkinson's disease;
• suffering from chronicrenaland / orhepatic insufficiency;
• suffering fromepileptic seizures;
• having a history of drug addiction;
• who have a historyacute psychosis.

Side effects

According to reviews, Midokalm is well tolerated and side effects go away on their own with a lower dose. According to the instructions, Miodocal can cause:

• Nausea, a feeling of discomfort in the abdomen or vomiting;
• Muscle weakness, arterial hypotension.
• Headache (with migraine you can try the medicineAnaprilin, which helpsit is effective).

Mydocalm according to reviews very rarely can cause various allergic reactions, such as erythema, itchy skin, angioedema, anaphylactic shock, urticaria and bronchospasm.

A source: http://remedy.ucoz.ru/index/midokalm_ot_chego_pomogaet/0-200

Midokalm with osteochondrosis

The main symptom of osteochondrosis is pain. It is present at almost all stages of the disease.

The intensity of the pain syndrome depends on the prevalence and extent of pathological changes in the tissues intervertebral discs and vertebrae, muscle fiber tension, neglect of the inflammatory process and a number of other factors.

One of the main ways to treat osteochondrosis is drug therapy. Unfortunately, not all of the assigned funds are highly efficient.

The effect of local drugs (ointments, gels) basically leads to a limited local effect, and many means of oral use do not affect the cause and can not eliminate the inflammatory process. In the treatment of osteochondrosis, Miodocalm proved to be a good candidate.

Muscle spasm constricts blood vessels

Why is it necessary to eliminate muscle spasm?

What is the danger of muscle spasm? In addition to provoking pain, reducing muscle fibers can lead to a number of serious consequences.

1. The main possible outcome of a spasm is the squeezing of blood vessels. Vascular depression leads to a violation of blood circulation. Especially dangerous is a similar phenomenon in cervical osteochondrosis, since its result is a violation cerebral circulation, insufficient supply of some parts of the brain with nutrients and oxygen. The use of Midokalm for this form of osteochondrosis is of paramount importance, since it helps to prevent the development of formidable complications.
2. Another consequence of muscle spasm is the compression of the nerve endings, which provokes the emergence of strong pains of an irradiating nature. In addition, the work of the internal organs, innervated by the injured fibers, may be disrupted.

The use of muscle relaxants in the treatment of diseases of the spine

Preparations of this group are used to relieve muscle tension in pathological lesions of the spine, including osteochondrosis.

Midokalm relieves muscle tension

The optimal way to get rid of spasmodic pains are muscle relaxants of central action, i.e. directed directly to the central nervous system, responsible for the regulation of the muscular tone. To this group belongs and Midokalm.

The results of numerous studies show that with the addition of muscle relaxants to the standard treatment of osteochondrosis on based non-steroidal anti-inflammatory drugs, analgesics, physiotherapy procedures and massage can significantly increase effectiveness of therapy, to achieve relief or reduce pain in a short time and increase the mobility of the damaged department vertebral column.

Advantages of using Midokalm

Application of Midokalma in osteochondrosis has a number of obvious advantages:

Mydocalm Tablets

• The central muscle relaxant effect that it has is highly selective. The drug reduces the degree of excitability of muscle fibers, but it does not have a suppressive effect on the nervous impulses, due to which the necessary muscular force is provided during movement and the correct posture.
• Even with prolonged use, Miodocalm is well tolerated and does not lead to dangerous side effects.
• Treatment with this muscle relaxant does not affect the patient's activity, does not reduce his physical and mental capacity for work.
• Midokalm fits perfectly into the traditional scheme of treatment of cervical, thoracic or lumbar osteochondrosis and is combined with other medications used.
• Due to the expressed miorelaksiruyuschey and analgesic effect, the drug can reduce the dosage of non-steroidal anti-inflammatory drugs. As a result, their negative side effect on internal organs is eliminated, and the effectiveness of osteochondrosis treatment is not reduced at all.

Currently, Mydocalm is considered the most effective and safe of existing muscle relaxants. In clinical practice, it has been used for more than 50 years.

About the preparation

Midokalm is used to treat neurological syndromes, accompanied by painful sensations, increased muscle tone and trophic disorders.

The active substance of the drug has a local anesthetic and membrane-stabilizing effect. With osteochondrosis and other diseases Midokalm:

The composition of Midokalma is lidocaine

• helps to eliminate muscle tension;
• leads to the appearance of an indirect analgesic effect;
• dilates blood vessels;
• improves blood circulation and lymphatic drainage.

Feedback from experts and patients indicate the rapid action of Miodocalm and its good tolerability.

Composition

The drug is available in the form of round tablets with a film coating.

Tablets with engraving "50" contain 50 mg of active substance - tolperisone hydrochloride, in tablets with engraving "150" of active substance, respectively, three times more. As auxiliary components in Midokalma used:

• monohydrate of citric acid;
• stearic acid;
• microcrystalline cellulose;
• silica;
• macrogol 6000;
• titanium dioxide;
• lactose monohydrate;
• dye.

The package contains 10 tablets.

Mydocalm as a solution for injection is released in darkened ampoules. Each ampoule contains:

• tolperisone - 100 mg;
• lidocaine hydrochloride mg.

As auxiliary components, in addition to the aforementioned substances, the following are used:

• iron oxide black;
• iron oxide red;
• iron oxide yellow.

The package contains 5 ampoules.

Midsection is taken with diseases of the spine

Indications for use

With osteochondrosis of any location (cervical, thoracic, lumbar), Midokalm is prescribed in the presence of reflex and compression syndromes.

The drug eliminates muscle stiffness and pathological high muscle tone. As a result, soreness decreases and stiffness of movements decreases.

In addition to osteochondrosis, the drug is prescribed for relaxation of skeletal muscles also with some other pathologies of the musculoskeletal system:

• spondylosis;
• spondylarthrosis;
• lumbar and cervical syndromes;
• arthrosis of large vessels.

Midokalm is prescribed for cerebral palsy, some other encephalopathies, accompanied by muscular dystonia.
The drug is also shown with a pathological increase in tone and the presence of muscle spasms, which are a consequence of neurological diseases of an organic nature:

1. myelopathy;
2. Multiple sclerosis;
3. encephalomyelitis and others.

Midokalm is also used after surgery for osteochondrosis, other orthopedic and traumatological surgical interventions.

The drug is taken three times a day

Contraindications

With osteochondrosis and other diseases Midokalm is not recommended for use when:

• hypersensitivity to tolperisone;
• allergies to lidocaine.

The drug is prescribed with caution in childhood. Babies under 1 year of age are not recommended to give it.

Instructions

With osteochondrosis, the dose of Midokalma is determined individually depending on several factors:

• features of the clinical picture and its severity;
• localization of the lesion (in the cervical, thoracic or lumbar region);
• the age of the patient;
• presence of concomitant diseases.

As a rule, adults are prescribed a three-time administration of Miodocalma (50 mg each). With severe spasms and a severe course of osteochondrosis, an increase in dosage of three times (three tablets three times a day after meals) is possible.

Children take Meadkalm in tablets of 50 mg each.

Children Midokalm appoint in tableted form to 50 mg. The daily dose should be divided into three parts. It is calculated according to the following scheme:

• for patients under 6 years - 5 mg per 1 kg of weight;
• for children from 7 to 14 years - 2-4 mg per 1 kg of weight.

If the child is difficult to swallow a pill, it should be rubbed.

The effect of the drug begins 40 minutes after ingestion. The recommended duration of the course is no more than 10 days.

Intramuscular injection: 200 mg / day. Divide into two groups.

Intravenous injection: 100 mg / day.

Compatibility with other drugs

Midokalm is compatible with other medications used for osteochondrosis of the spine.

In any case, there are no data confirming the manifestation of a negative effect from the simultaneous use of the drug with other drugs.

It is prescribed simultaneously with anti-inflammatory, analgesic, sedative, hypnotic drugs.

Application in pregnancy

The use of Midokalma for osteochondrosis in pregnant women is shown only in case of emergency. This especially applies to the first trimester. The remedy is also not recommended for lactation, during breast-feeding.

In pregnancy, Midokalm is undesirable

Side effects

According to the reviews, taking Mydocalm with osteochondrosis does not lead to serious undesirable effects. When they occur, the dosage is reduced. Possible side effects include:

• nausea, sometimes with vomiting;
• feeling of discomfort in the abdomen;
• headache;
• decrease in blood pressure (possible with rapid intravenous injection);
• muscle weakness;
• allergic reactions: skin itching, erythema, urticaria, bronchospasm, angioedema, anaphylactic shock.

What patients are saying about the drug

Reviews of patients with a diagnosis of "osteochondrosis which were taken or accepted by Midokalm, prove the efficacy and safety of the remedy.

A source: http://pozvonki.com/preparaty/midokalm/

Midokalm tablets - how to take: what helps the drug, the price and analogues of the medication, reviews about the action of the drug

A strong drug that normalizes blood circulation in the extremities of arthrosis, which can be purchased at a pharmacy on the prescription of a doctor, is Midokalm tablets.

For the treatment of neurological syndromes, it is a highly effective remedy, but it should be remembered that the remedy belongs to the group of mixed central muscle relaxants and has a direct effect on the central nervous system (CNS).

You can take Miodocalum only according to the doctor's prescription.

From what tablets Midokalm

Local anesthetizing drug Midokalm has a rapid targeted effect on the central nervous system and is used for treatment of joint diseases, osteochondrosis of the spine and other pathologies of the musculoskeletal system and vessels. Tablets have an antispasmodic effect (relieve spasm of smooth muscles of blood vessels), eliminate excessive muscle tension (muscle spasms), contribute to a decrease in the tone of skeletal muscles.

The main active substance of muscle relaxant (tolperisone hydrochloride) has a specific ability to relieve pain and normalize the trophism of the muscle tissues of the extremities.

In addition, Midokalm affects the membranes of cells, preventing their destruction, which occurs as a result of pathological processes in neurological diseases.

The form of the preparation of Mydocalm is biconvex round tablets containing 50 mg or 150 mg of tolperisone hydrochloride (as indicated by engraving 50 or 150 on one side of the tablet).

Each pill is coated with a white film coating and has a weak specific odor. Mydocalm is packaged in blisters of 10 tablets in each. Cardboard pack contains 3 blisters and instructions for the use of the medicine.

The component composition of each tablet is given in the table:

Substance	Amount in tablets containing 50 mg of tolperisone hydrochloride, mg	Amount in tablets containing 150 mg tolperisone hydrochloride, mg
The core of the tablet
Tolperisone hydrochloride	50	150
Citric acid monohydrate	, 3	, 9
Colloidal anhydrous silicon dioxide	,	,
Cetylacetic acid (stearic acid)	,	,
Magnesium silicate with hydroxyl (talc)	,	1,
Microcrystalline cellulose	14	42
Corn starch	2, 7	8, 1
Lactose Monohydrate	4,	14,
Film sheath
Colloidal anhydrous silicon dioxide	, 45	, 89
Titanium dioxide	, 44	, 87
Lactose Monohydrate	, 92	, 85
Polymer of ethylene glycol Macrogol	, 92	, 85
Methyloxypropylcellulose (hypromellose)	, 27	, 54

How the drug works

Mydocalm selectively oppresses the caudal part (located closer to the end) of the aggregate of cellular clusters of the brain that leads to the blocking of cholinergic receptors (membrane proteins) responsible for the conversion of energy into nerve impulses and muscle reduction.The mechanism of action of tablets is to inhibit the impulsivity of motor neurons and block spinal reflexes.

Strengthening circulation of blood and lymph is due to facilitating the conduct of excitation pulses along the reticulospinal pathway.

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After getting into the stomach, the substance of tolperisone is absorbed from the digestive tract, reaching a maximum concentration level in the blood after 30-60 minutes.

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It is excreted from the body with urine in the form of intermediate products of cellular metabolism.

Indications for use of Midokalma

Indication for the use of a strong muscle relaxant is a pathologically increased muscle tone, which occurs with CNS diseases and provokes pain syndrome. A neurologist can prescribe Medocalm in the following cases:

• in the treatment of osteochondrosis to eliminate severe pain syndrome;
• for relief of attacks of severe pains that occur against a background of vascular innervation disorders;
• with combined treatment of osteochondrosis, arteriosclerosis, diffuse scleroderma;
• for the removal of muscle spasms with restorative postoperative therapy;
• for the treatment of non-inflammatory brain diseases accompanied by muscular dystonia;
• as therapy of the raised muscular tonus arising at pathologies of system of organs of movement;
• with ischemic stroke to relieve spasms of cerebral vessels.

The scheme of reception of a muscle relaxant on the basis of tolperisone is appointed by the doctor, proceeding from indications for its application.

Instructions for the drug Midokalm Tablets contains general recommendations for the use of the drug.

The drug should be taken after meals to increase the bioavailability of tolperisone. Swallow the pill completely, with water.

Children older than 7 years use 3-5 mg tolperisone per kg of body weight three times a day. Adult patients older than 14 years take 100-150 mg per day (divided into 3 doses).

During the course of treatment, the dosage gradually increases to 450 mg per day.

special instructions

Midokalm should be taken in strict accordance with the instructions and recommendations of the treating doctor.

Targeted studies of the influence of muscle relaxant on the concentration of attention and the ability to control mechanisms and vehicles were not conducted.

The patients' testimonies testify that for the whole practice of the use of the tablets, the hypnotic effect and the decrease in the reaction rate after the reception was not observed.

In pregnancy

Admission Midokalma in the first trimester of pregnancy is not recommended, because there is no clinically confirmed evidence of drug safety for normal embryo development. Beginning in the second trimester, tablets can be prescribed by a doctor if the expected therapeutic effect of their administration is higher than the potential hazard to the fetus.

Drug Interactions

Instructions for use Midokalm does not contain restrictive instructions about the simultaneous intake of other medications.

The effect on the central nervous system is not accompanied by a sedative effect, so the muscle relaxant can be combined with hypnotics.

It should be borne in mind that taking both muscle relaxant and non-steroidal anti-inflammatory drugs, tolperisone enhances the action of niflumic acid. Midokalm enhances the muscle relaxant effect under the influence of psychotropic drugs and clonidine.

Midsummer and alcohol

During the research it was established that the drug does not affect the effect of ethanol-containing substances on the CNS.

Medicines containing ethanol are permitted for use during treatment.

The use of alcohol during treatment with the drug Midokalm is not prohibited, although this combination can have a sedative effect if you abuse alcohol-containing drinks.

Side effects

Tablets containing tolperisone are well tolerated by patients, but the risk of side effects is not ruled out. The most frequent manifestations of side effects that require discontinuation of the drug include the following conditions:

• nausea;
• vomiting;
• headache;
• weakness in the muscles;
• increased irritability;
• hypotension.

Overdose

Registered data on cases of overdose of Miodocalma tablets and its consequences are absent.

Based on the clinical studies, we can conclude that after a single dose of 600 mg of hydrochloride tolperisone may show the following signs of an overdose, which should be eliminated by rinsing the gastrointestinal tract:

• ataxia;
• muscular hypotension;
• intentional tremor;
• paralysis of the respiratory center;
• dyspnea;
• convulsions.

Contraindications

The doctor, appointing Midokalm, must make sure that the patient does not belong to the category of patients who are contraindicated in taking the muscle relaxant.

These categories include breastfeeding women, children and elderly patients.

In order to avoid unpleasant consequences, the neurologist should be warned if:

• hypersensitivity to lidocaine;
• there is an allergy to tolperisone hydrochloride;
• diagnosed myasthenia gravis;
• pregnancy is planned;
• a history of severe impairment of kidney function;
• there is a tendency to an allergic reaction to medications.

Terms of Sale and Storage

Miorelaxant Meadokalm belongs to the list B medicines (potent medicines) and is released only on the basis of the prescription prescribed by the doctor.

Store the drug should be at a temperature of +15 to +30 degrees in a place difficult to reach for children.

After three years from the date of manufacture of the medicine (indicated on the packaging), it should not be used.

Analogues

A similar pharmacological action or a similar active ingredient of Mediglobal analogs does not mean that it is possible to replace the patient's prescribed muscle relaxant himself.

The mechanism of action on the body for different drugs is different, so the possibility of using a particular medicine should be approved by the treating doctor.

The most popular analogues of Midokalm are:

• Meprothan;
• Sirdalud;
• Tisaloud;
• Baclofen;
• Tolperisone;
• Miolgin.

Price of Midokalma

The price of Miodocalma in tablets ranges from 294 to 499 rubles per 30 pcs. and depends on the amount of active substance in 1 pill. The table shows the prices of tablets in pharmacies:

Amount of active ingredient	Pharmacy	Price Mydocalm
50	Dialog	294
50	ZdravCity	324
50	Econom	311
50	Terravita	327
50	Help window	356
50	Zulu Ru	373
50	Eco World	479
50	Alfega	400
150	Aster	359
150	Onfarm	365
150	Clover Pharma	378
150	Sun	439
150	A-Pharm	499

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