Ambrobe is considered one of the often prescribed medications, which has an expectorant and mucolytic properties.
Most often, this remedy is used to treat a cough that is a sign of an infection. Thanks to cough, bronchial tubes are cleaned from various barriers that prevent normal breathing. It is for this reason that drug therapy for coughing is aimed at excretion of sputum from the respiratory tract.
On this page you will find all information about the Ambrobene tablets: a complete instruction on the use of this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Ambrobene. Want to leave your opinion? Please write in the comments.
Clinical and pharmacological group
Conditions of leave from pharmacies
The drug is approved for use as a remedyover-the-counter vacation.
Price list
How much are Ambrobene tablets? The average price in pharmacies is at the level of160 rubles.
Form of issue and composition
The main component of the instructions for the use of tablets Ambrobene 30 mg calls ambroxol hydrochloride. This substance has a mucolytic effect on the body:
- liquefies phlegm;
- helps to excrete mucus.
Ambroxol, absorbed through the gastrointestinal tract into the blood, begins to exert an effect on the body as early as 30 minutes after ingestion. The tablet also includes additional ingredients: lactose, starch and other substances.
Pharmacological effect
The medicine "Ambrobene", from which it is popular in patients, was developed as a mucolytic and expectorant. It activates the excretion of pathological sputum from pulmonary structures, having a direct effect on its adhesive properties. The medication is able to strengthen the production of special enzymes that bear direct responsibility for the rapid cleavage of bridges between the polysaccharides of the bronchial secretion.
Of other useful properties of the drug Ambrobene, the instructions for use confirm this, it is possible to indicate its ability to stimulate activity cellular elements of the mucosa in the bronchi, stabilize the process of formation of surfactant, improve the motor activity of the ciliated layer. This, in general, has the most positive effect on sputum discharge.
Indications for use
All forms of the drug are used for diseases of the respiratory tract with the release of viscous sputum and the difficulty of its divergence:
- acute and chronic bronchitis;
- pneumonia;
- bronchial asthma;
- bronchiectatic disease;
- as part of complex therapy to stimulate the synthesis of surfactant for respiratory distress syndrome in premature infants and newborns (injection solution).
Contraindications
When treating the disease with Ambrobene tablets, their effect on the duodenum and stomach is possible. In addition, the processing and removal of ambroxol from the body by an unhealthy liver exacerbates the situation. It is for this reason that you will have to give up tablet treatment in the following cases:
- pathology of the liver and kidneys of a chronic nature that cause disruption of their work
- increased individual sensitivity to certain components of the drug
- chronic gastritis
- ulcer of the duodenum and stomach
If necessary, cough treatment in childhood is not recommended to use Ambrobene tablets up to 6 years, for such small children a solution or syrup is produced.
With increased caution and under the supervision of a doctor, it is necessary to drink Ambrobene tablets in cases when the patient has bronchial motor function impaired. If too much secreted secretion increases the risk of its stagnation in the lungs.
Application in pregnancy and lactation
There is insufficient data on the use of ambroxol in pregnancy, especially in the first 28 weeks. The use of Ambrobene in the II and III trimesters of pregnancy is possible only according to the doctor's prescription, after a thorough evaluation of the expected benefit of therapy for the mother and the potential risk to the fetus.
The use of the drug in women during lactation has not been studied enough, so Ambrobene can be taken only for the intended purpose doctor, after a thorough assessment of the relationship between the expected benefit of therapy for the mother and the potential risk to the infant.
ATexperimental researchthere was no teratogenic effect on animals; It is shown that ambroxol is excreted in breast milk.
Instructions for use Ambrobene in the form of tablets
The instructions for use indicate that the duration of treatment is determined individually depending on the course of the disease. It is not recommended to take Ambrobene without a doctor's appointment for more than 4-5 days. The mucolytic effect of the drug manifests itself when a large amount of liquid is taken. Therefore, during treatment, a generous drink is recommended.
Tablets should be swallowed whole, without chewing, after eating, squeezed large amounts of liquid:
- Children aged 6 to 12 yearsshould be taken on 1/2 tab. 2-3 times / day (15 mg ambroksola 2-3 times / day).
- Adults and children over 12 years of agein the first 2-3 days of treatment should take 1 tab. 3 times / day (30 mg ambroksola 3 times / day). If therapy is ineffective, adults can increase the dose to 2 tablets. 2 times / day (120 mg ambroksola / day). In the following days should take 1 tab. 2 times / day (30 mg ambroksola 2 times / day).
Side effects
Tablets, capsules and syrup Ambrobene occasionally can cause allergic reactions (skin rash, itching, urticaria, dyspnea, angioedema), as well as weakness, headache, fever. In very rare cases, the use of the drug may cause anaphylactic reactions. Side effects of the drug may manifest as nausea, vomiting, diarrhea, abdominal pain, constipation, exanthema, rhinorrhea, dysuria, dry mouth.
Ambrobene solutions for inhalation and intravenous administration also in rare cases can cause hives, itching, angioedema, nausea, vomiting, abdominal pain and anaphylactic reactions.
A solution for inhalation may have a side effect in the form of a violation of taste perception, and a solution for injections with rapid administration cause a feeling of fatigue and weakness, severe headaches, venous edema.
Overdose
In the case of a significant increase in the concentration of the drug in an organism exceeding the therapeutic dose, nausea, vomiting, diarrhea (diarrhea) of nervous excitation may develop. If such symptoms appear that indicate a possible overdose, seek medical attention.
special instructions
Contraindicated Ambrobene combination with antitussive drugs, making it difficult to withdraw phlegm.
Very rarely, when Ambrobene is used, skin reactions in severe form are observed, such as Stevens-Johnson syndrome and Lyell's syndrome. When changing skin or mucous membranes, the patient should immediately call a doctor and stop taking the drug.
The drug does not affect the ability to drive a car or other complex mechanisms.
When using Ambrobene in the form of a syrup, one measuring cup (5 ml of syrup) contains 2.1 g of sorbitol, which corresponds to 0.18 XE.
Analogues
Drugs that contain ambroxol - Ambrosan, Lazolvan, Bronhoksol, Medox, Flavamed.
Before using analogues, consult your doctor.
Storage conditions and shelf life
The drug should be stored out of reach of children at a temperature of no higher than 25 ° C. Shelf life - 5 years.
How to choose probiotics for the intestine: a list of drugs.
Effective and inexpensive cough syrups for children and adults.
Modern non-steroidal anti-inflammatory drugs.
Review of tablets from the increased pressure of the new generation.
Antiviral drugs are inexpensive and effective.
