Why use Karsil: instructions and feedback from people

Karsil is a hepatoprotective drug, which contains a dried extract of the milk thistle fruit, which is an analog of silymarin.

It is used for various disorders of functions and liver diseases, and also as a preventive agent. The advantage of the drug is a vegetative active basis, namely, the fruits of milk thistle, which have been used for the treatment of liver pathologies since ancient times.

On this page you will find all information about Karsil: full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Karsil. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Antitoxic, hepatoprotective action.

Conditions of leave from pharmacies

Released without a doctor's prescription.

Price list

How much does Karsil cost? The average price in pharmacies is at the level of350 rubles.

Form of issue and composition

Tablets, coated with an outer layer of brown color and an inner layer of white, biconvex form; on the break - from brownish-yellow to light-brown color.

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1 dragee Karsila:

Dry extract of the milk thistle fruit (equivalent to silymarin) - 35 mg;
Excipients: lactose monohydrate, wheat starch, povidone (colidon 25), microcrystalline cellulose, magnesium stearate, talc, dextrose monohydrate, sorbitol, sodium hydrogen carbonate.

1 capsule:

dry extract of milk thistle fruit - 163.6-225 mg;
Excipients: lactose monohydrate, microcrystalline cellulose (type 101), wheat starch, povidone K25, polysorbate, silicon dioxide colloidal anhydrous, mannitol, crospovidone, sodium hydrogen carbonate, magnesium stearate.

Karsil or Karsil Forte - what is better?

In this case, the choice of the drug is determined only by the severity of liver damage, since the differences between these two medicines Karsil / Karsil Forte consist only in their form (tablets / capsules), the mass content of silymarin (22.5 / 90 mg) and some change in the composition of the additional ingredients.

Pharmacological effect

Means of plant origin. The main is the hepatoprotective effect. Flavolignans, incl. silybin, dehydrosilybin, isosilibin, silymarin, dehydrosilimarin, silichristine, tasifolin (2.8-3.8%) stabilize the lysosomal and cell membranes, preventing the release of enzymes from the cells. Interact with free radicals and inhibit the processes of lipid peroxidation. Due to the antioxidant effect, the penetration of various toxins into the liver cells (including chlorinated hydrocarbons, alpha-amanitine pale toadstool, nitrosamines) is inhibited. Silybin, silymarin and their derivatives stimulate specific RNA polymerase A, as a result of this, the synthesis of proteins and phospholipids in hepatocytes, the processes of regeneration and detoxification in the liver are accelerated.

Normalization of metabolic processes is promoted by tocopherols, macro- (potassium, magnesium) and microelements (copper, selenium) contained in the fruits. In fatty fruit (20-34%) contains a large number of unsaturated fatty acids (including linoleic - 50-62%), which have redox properties, promote the oxidation of cholesterol and, together with beta-sitosterol, prevent atherosclerosis. Polysaccharides of mucus (5%) have an enveloping and gastroprotective effect. The nitrogen-containing compound betaine improves the process of digestion, bile in the liver. Fruits of thistle have a lactogenic effect.

Indications for use

What helps? Karsil is prescribed for the following diseases:

Toxic liver damage.
Chronic hepatitis of non-viral genesis.
Cirrhosis of the liver (as an additional agent).
Chronic intoxication, as well as steatosis of the liver (both alcoholic and nonalcoholic).

The use of Karsil is effective as a preventive agent for prolonged drug therapy and prolonged use of alcohol.

Contraindications

Before using the product, it is recommended that you carefully read the enclosed instructions. Contraindications include:

Individual intolerance to the drug;
Age before 12 years.

Application in pregnancy and lactation

Data on the safety of taking the drug during pregnancy are absent. Apply Karsil in the treatment of a pregnant woman can only on special indications. At the same time, the expectant mother must be constantly under medical supervision.

Also, it is not recommended to treat with breastfeeding Karsil. In the case of the use of the drug, it is necessary to refuse lactation and transfer the baby to artificial feeding

Instructions for use

The instructions for use indicate that Karsil or Karsil Forte is taken orally, before eating, with enough drinking water. Dragee can not be chewed, and capsules - to open. In case of skipping one of the receptions, it is recommended to drink the medicine as soon as possible, but not to take a double dose at the subsequent reception.

Dosage and duration of admission are determined by the doctor and depend on the age and diagnosis of the patient. As a rule, the course of admission is at least 3 months.

Karsil Dosage for adults:

In severe liver diseases - 4 dragees 3 times a day;
In cases of mild course of the disease and as a supporting treatment - 1-2 tablets 3 times a day;
For prevention - 2-3 tablets during the day.

Dosage of Karsil Forte for adults:

In severe liver pathologies - 1 capsule 3 times a day;
In cases of mild course of the disease and as a supportive treatment - 1 capsule 1 or 2 times a day;
For prevention - 1 capsule 1 time per day.

Carlsil dosage for children from 12 to 18 years:

In severe liver diseases - 4 dragees 3 times a day;
In cases of mild course of the disease and as a supporting treatment - 1-2 tablets 3 times a day;
For prevention - 2-3 tablets during the day.

Dosage of Karsil Forte for children from 12 to 18 years:

In severe liver pathologies - 1 capsule 3 times a day;
In cases of mild course of the disease and as a supportive treatment - 1 capsule 1 or 2 times a day;
For prevention - 1 capsule 1 time per day.

If you accidentally take a high dose of Karsila, it is recommended to induce vomiting and perform a gastric lavage. After this, it is necessary to take the sorbent and, if necessary, to carry out symptomatic therapy.

Side effects

The use of Karsil can cause such side effects as:

Dyspeptic disorders (nausea, vomiting, feeling of fullness of the stomach, pain in the epigastric region, bloating, diarrhea);
Allergic manifestations (rash, itchy skin);
Alopecia (pathological hair loss, which leads to their thinning or complete disappearance in some areas of the head or trunk);
exacerbation of vestibular disorders (if any).

Most patients and doctors leave positive comments about Karsil, if adverse reactions occur, they disappear after discontinuation of treatment.

Overdose

Cases of drug overdose Karsil have not been reported, but to avoid the risk of side effects should not be exceed the dose recommended in the instructions, otherwise the patient may develop signs of dyspepsia.

When accidentally ingesting a large quantity of pills, the patient is washed with a stomach and allowed to take enterosorbents. As a rule, this is enough.

special instructions

During therapy, the appearance of estrogen-like action of silymarin is possible. In this regard, a patient with hormonal disorders (uterine fibroids, endometriosis, prostate carcinoma, uterus, breast, ovaries) is prescribed with caution.

It should be borne in mind that the composition of Karsila includes wheat starch (may be dangerous for patients with gluten enteropathy (celiac disease)) and glycerol (in high doses can be irritating to the mucous membrane of the stomach and cause a headache).

Drug Interactions

The active ingredient of Carlsil (silymarin) can interact with other drugs:

Reduce the contraceptive effect of oral contraceptives.
Strengthen the effect of such drugs as: ketoconazole, Vinblastine, Diazepam, Lovastatin, Alprazolam;

Reviews

We picked up some feedback from people about the drug Karsil:

Elizabeth. I have a friend who takes karsil before every plentiful meal since the Soviet times, she is now almost 60 years old, and she looks at a maximum of about 50.
Yuri. I was convinced of the positive effect of the "Karsil" tablets after repeated application, which gave a quick result. Sometimes the pain that occurs in the liver region for a long time does not give rest after taking even a small portion of alcohol, and after the use of these pills everything quickly comes back to normal. And for prevention, I think, there is no simpler and cheaper drugs than "Karsil", which have their health-improving effect quite quickly. It is also good that the drug is inexpensive. "Karsil" is always with me at home and at work. I sin with love for spicy food, and as a result - unpleasant heaviness in the side, nausea. And than, how not "Karsilom", quickly and effectively cope with negative manifestations? Only "Karsil"!
Lena. I drank for the liver "Karsil", like normal, but nothing unusual in the change in the state did not notice. Then I switched to "Hepatium", these are German vitamins. Saw in January, because after the new year something oh-oh, how hard it was for me. At me always with a liver was not so, and after holidays gravity was terrible, though a wolf howl. Well, nothing, with these vitamins recovered for half a month.

Analogues

Preparations with a similar spectrum of action and similar composition are many, among the most popular:

Hepa_Mertz;
Essley Forte;
Antral;
Energetic;
Hepatox;
Heptral;
Livolin Forte;
Phosphogliv;
Essentiale Forte H;
Lecithin;
Orniliv;
Legalon;
Thistle tablets;
Geparsil.

Before using analogues, consult your doctor.

Essential H or Karsil - which is better?

It is impossible to give an unambiguous answer, which of these drugs is better. Both drugs are representatives of one group - hepatoprotectors, both positively affect the protection and recovery cells of the liver, but differ in composition (the active ingredient Essentiale - essential phospholipids) and the mechanism of action on the liver. In the case of using Karsil, first of all, a protective function can be traced, and the Essentiale effects are more aimed at restoring the cellular structure and regeneration.

Precisely the same actions should be followed when choosing between oral medications Karsil or Essentiale Forte N. What is better to take the patient with a different severity of liver damage, can recommend only the doctor after a comprehensive study of the problem.

"Karsil" or "Liv. 52 »- what is better?

In this case is analogous to the above. Both analogs are effective and are used for the same type of indications. The drug "Liv. 52 "has other herbal ingredients, additionally shows choleretic effect. Both medicines are interchangeable and complementary. However, doctors still prefer the "Karsil" tablets than the Indian counterpart.