Cefekon D

Cefepon D - antipyretic and analgesic. It helps to return the threshold of thermoregulation to a normal level and fights inflammatory processes.

These candles are used to treat children from 3 months to 12 years. It is used to reduce body temperature with a variety of childhood infections, such as measles, chickenpox or scarlet fever, during acute respiratory infections and with an increase in temperature during the post-vaccination period.

Effective anesthetic during teething. It alleviates headache and muscle pain. As a febrifuge, Cefexon D candles are used no longer than 3 days, and as an analgesic agent - no more than 5 days. In the absence of the expected therapeutic effect, you need to see a doctor to clarify the diagnosis and selection of another medication.

Clinical and pharmacological group

Analgetic-antipyretic.

Terms of sale from pharmacies

Can buywithout a doctor's prescription.

Price

How much does Cefecon cost in pharmacies? The average price is at the level of35 rubles.

Composition and form of release

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The main active ingredient of the drug is paracetamol, auxiliary fat is solid. Candles Cefekon D are available in 10 suppositories in a package in different dosages, which are easy to recognize by color.

For children1-3 months of 50 mg of paracetamolin each candle - in a gently pink package.
For childrenfrom 3 months to 3 years of 100 mg of paracetamolin each candle - in a red package.
For childrenfrom 3 to 12 years, 250 mg of paracetamolin each candle - in a bright pink package.

Pharmacological effect

Cefekon D refers to a group of non-narcotic analgesics. The active substance is paracetamol. It blocks the enzyme cyclooxygenase at the level of the center of thermoregulation of the brain. This helps to significantly reduce the production of prostaglandins, substances that cause inflammation, in addition, it returns normal thermoregulation. This allows Cefekon D to have an analgesic and antipyretic effect, without changing the normal body temperature.

The anti-inflammatory effect of paracetamol is not strongly pronounced due to the fact that cellular enzymes peroxidase destroy it in tissues. The use of Cefekon D does not adversely affect the mucous membranes of the intestine and stomach, and also does not retain excess water and sodium ions in the body. Absorption of paracetamol from rectal suppositories occurs in the arterial network of the rectum. Approximately in half an hour-hour the maximum concentration of a preparation in a blood is reached.

Cefekon D can penetrate through the placental and blood-brain barrier. This drug is metabolized in the liver. When rectal medicine is used, the liver passes its first pass. That is why the load on this organ with this method of drug administration is significantly reduced. Metabolites of paracetamol are excreted by means of kidneys with urine.

From what help candles Cefekon D?

The main indications are the following:

elevated body temperature in a child with ARVI, influenza, infectious diseases and other pathologies;
severe pain syndrome with headache and toothache, neuralgic conditions (according to the appointment of a specialist), as well as pain in trauma.

Contraindications

Individual hypersensitivity to the components of the drug, expressed violations of the liver and kidneys, a deficiency of glucose-6-phosphate dehydrogenase, children under 1 month of age, diseases of the blood system (anemia, thrombocytopenia, leukopenia).

With caution: renal and hepatic insufficiency, benign hyperbilirubinemia (including Gilbert's syndrome), viral hepatitis, alcoholic liver damage, alcoholism, pregnancy, lactation, simultaneous intake of other paracetamol-containing drugs.

Intended use for pregnancy and lactation

In the first trimester of pregnancy, Cefexon D suppositories are not prescribed to women. Paracetamol adversely affects the process of laying and forming the internal organs of the fetus and the use of candles in the first trimester of pregnancy by a woman can lead to anomalies in the development of a future child. Use of the drug in the 2nd and 3rd trimesters is possible with the permission of the doctor if the expected benefit for the mother exceeds the potential risk to the fetus.

The use of candles Cefekon D during lactation is possible without the abolition of breastfeeding. Paracetamol is excreted in breast milk, so before using suppositories of a nursing mother, you should consult your doctor.

Dosage and route of administration

As indicated in the instructions for use of the candle, Cefexon D is used rectally (in the rectum). For maximum therapeutic effect, the child must necessarily empty the intestine before introducing the candle.

The dose of the drug is determined by the doctor individually for each child, depending on the age and body weight. According to the instructions of the suppository, children of different ages are prescribed in the following dosage:

from 2 to 3 months (body weight more than 5 kg) - 50 mg at a time;
from 3 to 12 months - 100 mg at a time;
from 1 year to 3 years - 200 mg at a time (2 suppositories once);
from 3 to 10 years - 250 mg at a time;
from 10 to 12 years - 500 mg at a time (2 suppositories at a time).

The interval between the use of suppositories based on Paracetamol should be at least 4-5 hours, otherwise the risk of toxic damage to the liver increases.

As a febrifuge, Cefexon D candles are used no longer than 3 days, and as an analgesic agent - no more than 5 days.

Adverse Reactions

Among the side effects can be identified as follows:

nausea with vomiting;
anemia (expressed in increased weakness and lethargy);
leukopenia and other disorders of the circulatory system;
reactions of an allergic nature (itching and rash on the mucous membranes and skin, redness of the skin);
development of necrosis and nephritis;
local reactions (pain and itching sensation in the rectum, especially with prolonged use);
increased blood pressure and heart palpitations (occurs in rare cases, with heart disease and blood vessels in history).

When these effects occur, the use of suppositories should be stopped as soon as possible and medical care should be taken.

Overdose Symptoms

If the dose recommended in the instructions is significantly exceeded or suppositories are used for more than 7 days, the patient develops signs of an overdose, which are clinically manifested in the form of indomitable vomiting, diarrhea, electrolyte imbalance, impaired liver and kidney function.

When the first signs of an overdose appear, the use of suppositories should be stopped immediately and consult a doctor. The patient is symptomatically treated, until the patient stabilizes, the patient must be under the supervision of a doctor.

special instructions

The patient should be warned about the need to see a doctor if the fever lasts more than 3 days and the pain syndrome is more than 5 days.

It should avoid simultaneous application with other paracetamolosoderzhaschimi drugs, tk. this can cause an overdose of paracetamol.

When using the drug for more than 5-7 days, it is necessary to monitor the peripheral blood and the functional state of the liver. Paracetamol distorts the results of laboratory studies in the quantitative determination of glucose and uric acid in plasma.

Compatibility with other drugs

When using the drug, it is necessary to take into account the interaction with other drugs:

Inhibitors of microsomal oxidation (cimetidine) reduce the risk of hepatotoxic effects.
When taking concomitantly with salicylates, the likelihood of developing a nephrotoxic effect increases.
When combined with paracetamol, the toxic effects of chloramphenicol are enhanced.
When combined with paracetamol, the effect of anticoagulants of indirect action increases and the effectiveness of uricosuric agents decreases.

Inducers of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, flumecinol, rifampicin, phenylbutazone, tricyclic antidepressants), ethanol, hepatotoxic medicinal the drugs increase the production of hydroxylated active metabolites, which makes it possible to develop severe intoxication even with a slight overdose.

Patient Reviews

We offer you to read reviews of people who used Cefekon:

Svetlana. A very cool thing... we were knocked down by the temperature in an hour and did not rise again... the fangs are hurt very painfully to the child, put the candle as an anesthetic, like helps, passed after the introduction of about min 15. He falls asleep... Our poor children ...
Irina. We were completely useless. Temperature 39'5. Did not help at all. At first, she knocked down nurofen and rose again, decided to alternate with cefecon. After even two candles, no matter how much the temperature fell. The shelf life is in order. Storage as expected. Maybe it's a fake... All the same, the child's antipyretic... Believe and hope for it.
Marina. At my kid, and to him ten months under the influence of a virus infection acute laryngitis has developed. The condition was severe and was accompanied by high fever. In addition, he was tormented by a dry cough, and he could not at all consume not what to drink medicine. The doctor advised Cefekon in the form of candles. This was the best way out. We needed only one candle, and the child went on the mend, the temperature did not increase more so much. There were no side effects. A very good medicine and a comfortable form do not need a kid to swallow anything. Now I recommend all of my friends to treat babies.

Some parents are faced with the choice of "what is better: Cefekon or Nurofen?" And can Cefekon and Nurofen give the baby at the same time? These two drugs have different active substances (paracetamol and ibuprofen). Here everything is individual. In some cases, Cefekon is more effective, in others - Nurofen. To give concomitantly Cefekons Nurofen is not recommended. If the temperature rises between the reception, for example, of Nurofen, reduce by wiping. However, if your child takes Cefekon for five days and the temperature does not drop, then it is necessary to replace Cefekon with another drug. But you can not give a child one drug, between the methods of another.

Sometimes parents use to reduce the temperature of a child's candles for adults. This can not be done, since most parents can not correctly calculate the dose for the child. It is better to use a drug intended for children.

Analogues

Replace suppositories Cefekon D can be the following analogs:

Efferalgan;
Nurofen;
Paracetamol for children;
Tylenol for children;
Panadol;
Viferon;
Viburkol;
Wolpan;
Dafalgan.

Cefekon in candles has many analogues, which can also be used if there are no direct contraindications:

Paracetamol. This inexpensive tool (about 50 rubles) is available in the form of a syrup for children with a pleasant taste (its it is acceptable to take children from three months in the absence of nausea during elevated body temperature).
Efferalgan. For children, such a product is available in the form of suppositories and syrup. The main difference from Cefekon - the presence of a pronounced anti-inflammatory effect. The average cost of the drug is 130 rubles. As the active substance in the drug is also paracetamol
Panadol. The drug is available in the form of suppositories, suspension and syrup for children. The drug has an anti-inflammatory effect and does not have a negative effect on the stomach and intestines.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

Keep candles best in a cool place, preferably in the refrigerator. The shelf life of the drug is indicated on the package and is 2 years from the date of manufacture. Do not use candles after the expiration date.