Semax

Semax is a unique drug that possesses a mechanism of neurospecific effects on CNS nerve cells.

This synthetic drug has a nootropic effect and does not contain hormonal activity. Semax affects the generation of the memory process and promotes effective learning by increasing attention, concentration, helps to clearly analyze information coming from the external environment.

With the help of the preparation, adaptation of the whole organism to such ailments as hypoxia, cerebral ischemia is improved, protection against negative effects is developed, incl. and from anesthesia.

Clinical and pharmacological group

Nootropic preparation.

Terms of sale from pharmacies

It is possible to buy under the prescription of the doctor.

Price

How much are Semax drops in pharmacies? The average price is at the level of400 rubles.

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Composition and form of release

Dosage form - nasal drops,% and 1%: clear, colorless (3 ml in vials with a stopper pipette, in a pack of cardboard 1 bottle).

• Active substance: methionyl-glutamyl-histidyl-phenylalanyl-prolyl-glycyl-proline, in 1 ml of drops - 1 or 10 mg.

Auxiliary components: methylparahydroxybenzoate, purified water.

pharmachologic effect

Drops Semax, being an analogue of corticotropin, affect the body with the help of nootropic properties of substances that are in the composition. They have antihypoxic, psycho-stimulating and antioxidant effects, without disturbing the hormonal balance of the body.

The drug is aimed at improving the internal organization of the brain, CNS. Due to its restoring properties, the drug improves memory, renews the organization structural parts of memory, helping the body to better remember information, analyze it and concentrate. The help of the brain is also in adaptation to certain processes, for example, anesthesia or hypoxia. Helps cope with cerebral ischemia and other destructive effects on the central nervous system.

As a result of nervous exhaustion or mental fatigue, the body loses its concentration of attention, its mental abilities are significantly reduced, and there is a sluggishness in the operator's activity. In such situations, the course of the drug will help, which will not leave a trace of the problems.

These drops can be applied by the course or used once, depending on the degree of neglect of the problem and the necessary amount of help to the body. Based on the patients' reviews, the drug is absolutely safe: it does not provoke allergies, it is non-toxic and regardless of the time of application it does not cause habituation.

Indications for use

Drops,% are prescribed in the following cases:

• increase the adaptive capacity of the human body in extreme situations;
• prevention of mental fatigue in people leading monotonous operator activity in particularly stressful or stressful periods of work;
• discircular encephalopathy, transient disorders of cerebral circulation, neurotic disorders of various genesis, including. recovery period after a stroke, after ionizing radiation;
• intellectual-mnestic disorders in vascular lesions of the brain, conditions after anesthesia, neurosurgical operations, craniocerebral trauma;
• Atrophy of the optic nerve, neuritis of toxic-allergic and inflammatory origin;
• minimal brain dysfunction, incl. Attention Deficit Hyperactivity Disorder (ADHD) in children older than 7 years.

Drops of 1% are used in the complex treatment of moderate to severe ischemic stroke in an acute period.

Contraindications

• Acute mental disorders and conditions accompanied by anxiety;
• The period of pregnancy and breastfeeding;
• Convulsions, including in the anamnesis;
• Children under 7 years of age (for nasal drops,%);
• Children and adolescence under 18 years (for nasal drops,% for use in neurosurgical and ophthalmic practice, for drops of nasal 1%);
• Increased individual sensitivity to any of the components of the drug.

Intended use for pregnancy and lactation

The drug is not allowed to apply in the periods indicated.

Dosage and route of administration

As indicated in the instructions for use, Semax is applied intranasally. Keep the bottle with a closed cap.

Nasal drops,%

In 1 drop of solution (when using a pipette) contains 50 μg of active substance. For 1 time in each nasal passage, you can enter no more than 2-3 drops. In the case of a higher dose, administration should be done in several doses at intervals of 10-15 minutes.

Recommended dosing regimens depending on the indication:

• intellectual and mnestic disorders in vascular lesions of the brain, transient disorders of cerebral circulation, discirculatory encephalopathy: a single dose of 3-30 mkg / kg (200-2000 mcg), daily - 7-70 mkg / kg (500-5000 mkg), the frequency of application is up to 4 times a day, the duration of treatment is 10-14 days, if necessary, courses;
• condition after neurosurgical interventions, craniocerebral trauma, anesthesia: 40-50 μg / kg (1400-3500 mcg) 3 times a day for 3-5 days, if necessary, the duration of therapy is increased up to 14 days;
• neuritis and atrophy of the optic nerve: 100-150 mcg in each nasal passage 2-3 times a day, daily dose of 600-900 mcg, the duration of treatment is 7-10 days. If necessary, the drug is administered by endonasal electrophoresis - from the anode, using a current of 1 mA. The daily dose is 400-600 mcg. The duration of exposure is 8-12-15 minutes. The course of treatment is 7-10 days.

To prevent mental fatigue and improve the adaptive capacity of the human body, it is recommended to use Semax 2-3 drops in each nasal passage 2-3 times in the morning. The daily dose varies from 400 to 900 μg. The duration of therapy is 3-5 days, if necessary, repeat courses.

With minimal brain dysfunctions, children from 7 years of age are prescribed 1-2 drops of the drug (50-100 μg or 5-6 μg / kg) in each nasal passage 2 times a day - in the morning and in the evening. The maximum daily dose is 400 mcg. Duration of treatment is 30 days.

Nasal drops Semax 1%

One drop of a 1% solution of the drug contains 500 μg of the active ingredient.

• In the treatment of stroke of moderate severity, 3-2 drops of the agent are injected into each nostril at a time. Similar procedures are carried out up to 4 times a day, with a break between instillations at 4 hours. The cumulative daily dose is 6000-12000 μg.
• In the treatment of severe stroke, 4 drops of a drug are injected into each nostril at a time. Similar procedures are carried out up to 5 times a day, with a break between instillations of 3 hours. The cumulative daily dose is 1, 00-2, 00 μg.

Duration of treatment is 10 days.

Mode of application

If the vial is sealed with a plastic screw cap:

• when first used, remove the plastic screw cap and replace it with the supplied pipette with the lid;
• dial the drug into the pipette;
• slightly tilting his head to one side, squeezing the required number of drops of the drug on the mucosa of the nasal passage.

If the vial is capped with a dropper cap:

• it is necessary to carefully cut off the tip of the pipette, tightly close the pipette cap;
• Before use, flip the bottle to fill the entire pipette space;
• remove the cap and squeeze the required number of drops of the drug on the mucosa of the nasal passage.

The drug should be stored with a tightly closed pipette with a lid or plastic screw cap, or a lid-dropper.

Side effect

According to the instructions, Semax is usually well tolerated. With prolonged treatment, slight irritation of the nasal mucosa is possible.

Overdose

Symptoms of overdose were not detected even with a significant increase in dosage.

Interaction with other drugs

Semax quickly breaks down and does not enter the digestive tract, so chemically incompatible combinations are not formed.

Unintentional concurrent intranasal use with drugs that have a local vasoconstrictive effect is undesirable.

Reviews

We offer you to familiarize yourself with the reviews of people who used Semax drops:

1. Olga. I will not recommend, but I'll write the following: my dad was a diabetic and after a stroke, when he he overshot the sugar, he became insane, aggressive, did not hear or listen to anyone, we dripped him Semax droplets. While dripping, he resisted, threatened, so I held, my mother dripped. But it was worth it, after a few seconds he calmed down and came to himself, about the fact that he had an attack he could not remember. Therefore, personally for our family, Semax was a wand-zashchalochkoy.
2. Nika. I recommend Semax to everyone who has had a stroke. These drops helped my grandfather recover. After the stroke, a lot of drugs were prescribed, but we did not see any progress. Began to look for other medicines. As a result, Semax advised the district doctor. It turned out that semax is in the Russian standard of stroke treatment. Speech, mobility, attention at the grandfather began to be restored at last. The main thing is that optimism and the desire for life have returned to him! We also plan Semex courses for recovery.
3. Natalia. To me the doctor has appointed or nominated Semaks after operation, since. There was a general anesthesia, after which the processes of memory are allegedly deteriorating. I liked the fact that the drug is made in droplets, it was not necessary to swallow the bitter tablets. But here the irritation of the mucosa at the end of the application was a little - it felt an unpleasant itch in the nose, and it took 5 days to dig this solution. I had no other side effects on Semax personally, but my neighbor in the ward, who was also assigned to him, complained of a headache. Regarding the restoration of memory, I can not say anything definite, what was before the operation, this one remained after - like forgetfulness now I do not suffer.

Analogues

Below are the most common Semax analogues: Cerebrolysin, Amylonosar, Gynos, Glycine, Gliatilin, Aminalon, Delecite, Biotropil, Intellan, Lucetam, Priracetam, Omaron, Bifren, Stamin, Noofen, Fezam, Cerebril, Vinpocetine, Encephabol, The escotrope.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

Store with a tightly closed cap in a place out of the reach of children, protected from light, at temperatures up to 10 ° C. Do not freeze.

Shelf life - 2 years.

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