How to take Papazol: instructions for use

Papazol belongs to the group of antispasmodics. It has antihypertensive and arteriodilating action. This is a combination medicine, which contains papaverine and bendazole.

Papaverin is a blocker of phosphodiesterase and creatine phosphokinase inside smooth muscle cells of blood vessels. It helps to reduce the content of calcium inside cells, the accumulation of cyclic AMP and the emergence of vasolidataric effect.

Papazol is used to treat diseases accompanied by spasms of vessels and smooth muscles (zolecystitis, pancreatitis, ulcers) and increased blood pressure.

Clinical and pharmacological group

Combined drug, has antispasmodic, hypotensive, vasodilating effect.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Papazol cost in pharmacies? The average price is at the level of15 rubles.

Form of issue and composition

Flat in the form of a cylinder white or white-gray tablets with impregnations. Papazol is produced in cans of 10, 20, 25, 30, 40, 50 and 60 pieces and in cardboard packages, with or without 10 pieces. PAPROP UBF - in cardboard packs of 10, 20, 30, 50 pieces, in a package with or without cells.

Each tablet contains 2 active ingredients - Dibasol in the form of Bendazol hydrochloride and Papaverine hydrochloride, 0.03 g each. As auxiliary components are potato starch, calcium stearate, lactose monohydrate.

Pharmacological effect

According to the instructions to the Pape, the effect of the drug is due to the constituent components:

1. Bendazol - spasmolytic myotropic action, which has a vasodilating and hypotensive effect. Also this substance stimulates the function of the spinal cord, has a moderate immunostimulating effect.
2. Papaverin is an antispasmodic with hypotensive effect. This substance also reduces the tone of the vessels, relaxes the smooth muscles of the internal organs (in particular, the gastrointestinal tract, urogenital and respiratory systems). When taken in high doses, papaverine slows intracardiac conduction, reduces the excitability of the heart muscle, and has a sedative effect.

Indications for use

Taking into account the described properties of the active substances, Papazol is used for:

1. Labile arterial hypertension (high blood pressure);
2. Peripheral paralysis of the facial nerve;
3. Residual phenomena after the transferred poliomyelitis;
4. Moderate spasms of peripheral arteries and cerebral vessels;
5. Spasms of smooth muscles of internal organs, incl. with peptic ulcer, duodenal ulcer, intestinal colic, spasm of the doorkeeper, cholecystitis, spastic colitis, urinary tract diseases.

Contraindications

There are certain conditions under which the use of "Papazol" tablets is prohibited. Contraindications include such conditions:

• epilepsy;
• violation of bronchial patency;
• insufficiency of liver or kidney function;
• age younger than 1 year;
• allergy to the components of the drug.

Doctors also note that "Papazol" is not recommended for children under the age of twelve or people with low blood pressure, as this can lead to weakness and deterioration of well-being. Ignoring these facts, it is possible to disrupt the effect of the action of the "Papazal" and bring harm, not to itself, but to itself.

Use in pregnancy and lactation

During pregnancy and lactation, the drug should be taken carefully under the close supervision of the doctor.

Dosage and route of administration

The instructions for use indicate that adult patients drink 1 tablet of Papazol 2 or 3 times a day 2 hours before meals or two hours after eating.

The length of the course of treatment depends on the individual characteristics of the patient and the nature of the course of the disease. As a rule, reviews about Papazole are confirmed, it is from 2 to 4 weeks (in adults).

The dosage of the drug and the duration of treatment in children are determined by the attending physician.

During the treatment with the drug should be excluded the intake of alcoholic beverages.

Side effects

On the background of drug treatment, patients may develop side effects:

1. Increased sweating;
2. From the central nervous system - dizziness, drowsiness, lethargy, weakness;
3. Allergic reactions - rash on the skin, hives, hyperemia of the face;
4. On the part of the digestive tract organs - nausea, constipation, bloating, lack of appetite, sometimes vomiting, dry mouth, changes in liver transaminase activity;
5. From the side of the cardiovascular system - violation of the heart rhythm, violation of conduction of the heart muscle, a decrease in the contractile function of the myocardium, tachycardia.

Overdose

The use of the papazole has practically no effect on the central nervous system, but its excessive dosage can produce a sedative effect.

About overdose Papazom may indicate such signs as:

1. Deterioration of vision.
2. Arterial hypotension.
3. Feeling of heat and intense sweating.
4. Dizziness and nausea.

Treatment: drug withdrawal, gastric lavage with activated charcoal, application of salt laxatives. Symptomatic therapy. There is no specific antidote.

special instructions

The drug is administered with caution in patients with reduced intestinal peristalsis, craniocerebral trauma, hypothyroidism, prostatic hypertrophy and adrenal insufficiency.

Drug Interactions

When using the drug, it is necessary to take into account the interaction with other drugs:

1. Papazn weakens the effect of anticholinesterase drugs on smooth muscles (galantamine, proserin, physiostigmine).
2. Adsorbents, astringent and enveloping medicines reduce the absorption of the drug in the digestive tract.
3. At simultaneous application of a preparation with spasmolytics, sedative drugs, diuretics, tricyclic antidepressants, procainamide, reserpine, quinidine, an increase in the severity of the hypotensive effect is possible.

Reviews

We picked up some reviews of people using the drug Papazol:

1. Tamara. I like the papal. Old drug. Proven. Reduces pressure gently but efficiently. Acts on a par with the now popular Enap. I would clarify that the papal helps me better than the enap. Adverse complications were not observed. It's just cheap, doctors do not prescribe it.
2. Artem. Yes, the papoid really gently reduces the increased pressure due to nervous stress, overwork, etc. That is, one-time, it is not suitable for permanent treatment, that is, with chronic hypertension. Papazol does not cause drowsiness, does not have a diuretic effect. The price of the drug is low, so I advise everyone to have it just in case.
3. Veronica. On Monday, there was hypertension. crisis / sudden drop of blood pressure, caused an emergency. The doctor gave 3 tablets and told me to chew them and hold them under my tongue, and then swallow it. It was a papal. After a while, the pressure began to drop and after 3 hours it dropped to 122/74, and it was 161/105. She felt fine, only slightly throat. Has bought or purchased to myself for the future 2 packs, and in general I drink constantly Lozap + in the morning and it is simple Lozap in the evening-was appointed or nominated by the cardiologist. The result is satisfied.

Analogues

The drug is affordable and unique in its composition. But in the pharmacy you can find analogues of the papazol, having a similar pharmacological effect:

• Enelbin;
• Vinoksim;
• Duzopharm;
• Dibazol;
• Andipal;
• Drotaverine;
• Pentalgin.

Before using analogues, consult your doctor.

Storage conditions and shelf life

The drug is suitable for use for 5 years from the date of release.

The optimum temperature for storage is below 25 ° C.

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