Cytovir 3

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Cytovir-3 (bendazole + alpha-glutamyl-tryptophan + ascorbic acid) is an immunostimulant with antiviral action and used in the treatment and prevention of influenza and other acute respiratory diseases, incl. in children.

It is able to have a positive effect on the responses of humoral and cellular immunity. Also, this drug has a beneficial effect on the nonspecific resistance of the body. In addition, the drug has an interferonogenic effect.It is considered one of the most effective means to speed up recovery and ease the course of the disease, as well as effectively carry out prevention.

All of the above properties of Cytovir-3 are due to the properties of the active substances that make up the drug.

Clinical and pharmacological group

Immunostimulating drug.

Terms of sale from pharmacies

Can buyby prescription.

Price

How much is cytovir 3 in pharmacies? The average price is at the level of300 rubles.

Composition and form of release

The drug is produced in different dosage forms:

  1. Capsules for oral administration (sometimes referred to as tablets);
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  3. Powder for solution (for children);
  4. Children's cytovir in the form of sweet syrup.

Active ingredients in the composition of 1 capsule, 1 ml of ready-made solution for oral administration and 1 ml of syrup:

  • alpha-glutamyl-tryptophan sodium 0.5 / 0.15 / 0.15 mg;
  • bendazole hydrochloride 20 / 1.25 / 1.25 mg;
  • ascorbic acid - 50/12/12 mg.

Auxiliary components:

  • 1 capsule: lactose monohydrate - 97.8 mg; calcium stearate - 1.7 mg; Shell (body / cap): titanium dioxide - 2/2%; dye yellow sunset sunset - 0 / 0.219%, dye azorubin - 0 / 0.0328%; gelatin - up to 100/100%;
  • 1 ml of the prepared solution (without flavor / with flavor): fructose - 386.6 / 386.2 mg; flavor identical to natural "Strawberry", "Orange" or "Cranberry" - 0 / , mg;
  • 1 ml of syrup: sucrose - 800 mg; Purified water - up to 1 ml.

Pharmacological effect

It is an immunomodulating drug used for immunostimulating and etiotropic therapy. It has an indirect antiviral effect against influenza types B and A, as well as other viruses that trigger the onset of ARVI.

Bendazol promotes the production of endogenous interferon with an immunostimulating effect. The component helps normalize the body's immune response. As a result, enzymes produced by interferon help to suppress the replication of the viral pathogen. Timogen is a synergist of the immunomodulatory effect of bendazole, which helps normalize the T-cell links of the immune system.

Ascorbic acid helps to activate the humoral links of immunity, improve the permeability of small vessels, which helps to reduce the inflammatory process in tissues. Ascorbic acid also has an antioxidant effect, neutralizing the oxygen radicals that always accompany the inflammatory process. Thus, the resistance of the organism to pathogens of the viral type in general is increased.

The maximum concentration of substances in the blood is observed only 4 hours after admission.

Indications for use

Citovir 3 is intended for the prevention and comprehensive treatment of acute respiratory viral infections and influenza in adults and children.

For adult patients and children older than 6 years, capsules of Cytovir are intended; for children, special dosage forms have been created from year to year: syrup and sweet solution for ingestion.

Contraindications

Absolute:

  • diabetes mellitus (syrup and solution for oral administration);
  • age up to 1 year (syrup and solution for oral administration) or 6 years (capsules);
  • pregnancy;
  • individual intolerance of the drug components.

Relative (diseases / conditions in which cytovir-3 is administered with caution):

  • arterial hypertension (before starting reception you should consult a doctor);
  • the period of breastfeeding (taking Citovir-3 with a curative / prophylactic goal is possible only in cases of exceeding the expected benefit over possible harm, consultation of a specialist is necessary).

Intended use for pregnancy and lactation

The drug is contraindicated for use in pregnancy and lactation.

Dosage and route of administration

As indicated in the instructions for use, cytovir 3 is taken orally 30 minutes before meals. Patterns of therapeutic and prophylactic use are identical.

  1. Children aged 1 to 3 years - 2 ml 3 times / day.
  2. Children aged 3 to 6 years - 4 ml 3 times / day.
  3. Children aged 6 to 10 years - 8 ml 3 times / day.
  4. Children over the age of 10 years - 12 ml 3 times / day.

The course of application - 4 days. If no improvement occurs after 3 days of treatment or the symptoms worsen, or new symptoms appear, you should consult your doctor.

  • If necessary, the course of prophylaxis is repeated after 3-4 weeks.

The drug should be taken only according to the method of administration and at the doses indicated in the instructions. The drug should be used only according to the indications specified in the instructions. If necessary, consult a doctor before taking the drug.

Instruction for capsules

Cytovir-3 capsules are intended for oral administration. They are taken 30 minutes before meals, swallowed whole and washed down with a sufficient amount of water. Recommended therapeutic dosage for adults and children over 6 years is 1 capsule 3 times a day.

The duration of the course of therapy or prevention of influenza, acute respiratory viral infection averages 4 days. If necessary, this course can be repeated after 3-4 weeks.

Adverse Reactions

The drug is fairly well tolerated by most patients. However, sometimes, the following side effects may occur when using the drug:

  • various manifestations of allergic reactions (reddening of the skin, itching, skin rashes);
  • a short decrease in blood pressure (observed in patients with neurocirculatory dystonia) - from the cardiovascular system.

Overdose Symptoms

Exceeding the recommended therapeutic dose with the development of overdose phenomena on the background of the use of capsovir-3 capsules may be accompanied by a decrease in the level of systemic arterial pressure (arterial hypotension), especially in the elderly and patients with concomitant vegetative-vascular dystonia hypotonic type.

In this case, symptomatic therapy is performed if necessary, as well as monitoring the level of arterial pressure and the functional state of the kidneys.

special instructions

After a second course, it is recommended to monitor the concentration of glucose in the blood.

The drug does not affect the ability to drive vehicles, work with moving mechanisms and engage in other potentially dangerous activities requiring increased concentration of attention and speed of psychomotor reactions.

Compatibility with other drugs

The interaction of alpha-glutamyl-tryptophan with drugs has not been revealed.

Possible simultaneous use with antiviral drugs and means of symptomatic therapy of influenza and ARVI.

If the patient is taking the above drugs or other drugs, he should consult a doctor.

Bendazole prevents the increase in OPSS caused by the use of nonselective beta-blockers. Strengthens the hypotensive effect (lowering blood pressure) of hypotensive and diuretic drugs. Fentolamine enhances the hypotensive effect of bendazole.

Ascorbic acid increases the concentration in the blood of tetracycline antibiotics and benzylpenicillin. Improves the absorption of iron in the intestine. Reduces the effectiveness of heparin and indirect anticoagulants. Acetylsalicylic acid (ASA), oral contraceptives, fresh juices and alkaline drink reduce its absorption and absorption. With simultaneous application with ASA, urinary excretion of ascorbic acid increases and the release of ASA decreases. ASA reduces the absorption of ascorbic acid by about 30%. Ascorbic acid increases the risk of developing crystalluria with the use of drugs containing ASA and sulfonamides short-acting, slows the excretion of the kidneys acids, increases the excretion of drugs that have an alkaline reaction (including alkaloids), reduces the concentration of oral contraceptives in the blood. With simultaneous use reduces the chronotropic effect of isoprenaline. Reduces the therapeutic effect of antipsychotics (neuroleptics) - phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants. Barbiturates and primidon increase the excretion of ascorbic acid in the urine.

Patient Reviews

We offer you to read reviews of people who used Citovir 3:

  1. Diana. We were recommended Citovir powder. We have children with allergies.... I do not know why, but that's what happened... diathesis, sneeze, cough... In 2 years - it was just a disaster - the flu, ARVI... there was simply no treatment for a child. For many drugs - a reaction. I went to a private clinic to a pediatrician. He prescribed Citovir powder. When he really helped the baby, I began to find out what kind of drug... On the Internet about him a lot is written. He is really good, for my allergy sufferer is suitable and therefore recommend it to anyone who has children, too, are allergic.
  2. Arseny. I took Citovir 3 in capsules, and in my opinion it helped, I can not say with certainty, because I did not do any research, but usually I had an acute respiratory viral infection complications on the bronchi, but this time he had been ill with only a viral infection, had been ill for only five days, the sixth was already completely healthy.
  3. Pauline. We have been using Citovir for 5 years now. We started with the first child. Previously, only syrup was on sale in pharmacies. He was drunk. But, if, the elder without claims (which "pill" mom gave, and swallow), then the baby has problems - the syrup for him is pretty sour. But the suspension goes to "Hooray"! Diluted the powder and forward, in an attack on viruses! The main thing is to be in time at the beginning of the illness. Then all the symptoms are very quickly released. Plus, immunity persists for a long time.

Numerous reviews on the syrup for children Citovir-3 were divided approximately as follows: 30% - negative, 70% - positive or close to neutral. Often patients who used the drug note the absence of "medicinal"Taste and a more convenient form of release (syrup) and compared with analogues (capsules, tablets, injections).

Reviews of doctors are more restrained, this is due to the widespread reluctance to recommend drugs that affect on the immune system, because of the limited knowledge of their effect on immunity in the long run.

Analogues

You can replace cytovir 3 with the following medicines:

  1. Avvirem is an antiviral agent active ingredient, which is rimantadine hydrochloride. It is produced in syrup, which is designed specifically for children aged 1-7 years. It is used to treat and prevent influenza A.
  2. Tamiflu refers to substitutes for the therapeutic group. He is prescribed for the prevention and treatment of influenza. The drug is in a suspension permitted for children older than a year and capsules they can be from 12 years.
  3. Aflubin is a substitute for the clinico-pharmacological group. Medicament is produced in drops and sublingual tablets used to treat and prevent ARVI in patients of any age, as well as to relieve arthralgia.
  4. Kagocel is an analogue of the pharmacological group. It is an antiviral and immunostimulating medication manufactured in tablets, which is used in patients if they are 3 years old for treatment and prevention of ARVI.
  5. Oscillococcinum is a homeopathic preparation, available in oral granules. It refers to drug substitutes for the pharmaco-therapeutic group. The agent can be prescribed for the treatment and prevention of acute respiratory viral infections. Before giving granules to babies they must be dissolved.

Before buying an analogue, consult your doctor.

Which is better: Orvirem or Cytovir?

The drugs have different mechanisms of action. In Citovir-3 mediated immunostimulating systemic action, and Orvire directly blocks the replication of viruses in the cell. Among patients, you can hear frequent complaints about the occurrence of an allergy to Orvirem in children.

Which is better: Kagocel or Cytovir?

Kagocel or Citovir similar to the mechanism of action and indications drugs. Hence, approximately the same responses from people who used drugs. Therefore, the choice is better to do, based on the recommendations of doctors and economic feasibility.

What is better than cytovir or Anaferon?

Although Anaferon is close to Citovir-3 according to the claimed effect, the mechanism of its action, as well as the majority of homeopathic preparations, has not been studied and is not proved in independent researches. Among patients and doctors, there is a constant debate about its usefulness.

Shelf life and storage conditions

Shelf life of the drug is 2 years (unopened bottle) and 10 days after dissection. It is not recommended to store medicinal product in the open sun, the temperature of the air in the room should not be more than 25 degrees. Do not use after the expiration date.


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