Nyxes and pills Mexiprem: instructions and reviews

Mexuprem is an antioxidant drug.

It is able to produce inhibition of free oxygen forms (formed by lipid peroxidation), to stabilize and protect against damage to the cell membrane (reduces viscosity of the membrane, and also increases its fluidity), and also provide nootropic, anticonvulsant (lung), anxiolytic and anti-stress action.

The drug improves the body's resistance to external damaging factors.

Clinical and pharmacological group

Antioxidant drug.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Meximeprime cost? The average price in pharmacies is at the level of190 rubles for tablets and 370 rubles for a solution.

Form of issue and composition

The preparation is produced in the form of round tablets having a biconvex form and covered with a specialized coating of white or cream shade, as well as in the form of a solution for injection, which is a liquid of a transparent colorless or pale yellow color.

The solution intended for the preparation of injections is packaged in ampoules of 2 or 5 ml. in each and placed in contour cells. One carton can contain 20, 50 or 100 ampoules complete with a special knife for their opening.

Composition of 1 ml of solution:

• active ingredient: ethylmethyl hydroxypyridine succinate 50 mg;
• excipient: water for injection - up to 1 ml.

Composition of 1 tablet:

• active substance: ethylmethyl hydroxypyridine succinate in terms of 100% substance - 125 mg;
• auxiliary substances: kaolin - 2.47 mg; calcium stearate - 2.75 mg; talc - 5.3 mg; sodium carboxymethyl starch - 12.58 mg; povidone - 13.4 mg; microcrystalline cellulose - 113.5 mg;
• shell: talc - 0.37 mg; macrogol - , 8 mg; titanium dioxide - 1.65 mg; hypromellose - 4.95 mg.

Pharmacological effect

Since the Mexiprim drug refers to the antioxidants of the heteroaromatic series, it has a wide range of uses. The drug increases the body's resistance to stressful situations. When the drug is used, its anxiolytic properties are manifested, without any muscle relaxant effects or drowsiness.

The medication reduces and prevents the occurrence of memory and learning disabilities, has a nootropic and anticonvulsant effect on elderly patients. Thanks to its antihypoxic and antioxidant abilities, "Mexiprem" contributes to the increase of efficiency and concentration of attention, and in addition, minimizes the harmful toxic effects of alcoholic beverages.

The drug has a positive effect on the brain tissue, as well as the circulatory system of the body due to stimulation of blood microcirculation and platelet aggregation. The drug lowers cholesterol due to its pronounced lipid-lowering abilities. When ingested, the drug is rapidly metabolized and transformed into glucuronoconjugated degradation products.

Indications for use

The tablet form is administered when:

1. Intellectual insufficiency in gerontology;
2. Stressful effects;
3. Anxiety states against a background of neuroses, neurosis-like conditions;
4. Vegetosovascular dystonia;
5. Cognitive disorders;
6. Alcohol abstinence with vegetovascular manifestations.

The injection form is assigned when:

1. Alcohol withdrawal syndrome;
2. Dyscirculatory encephalopathy;
3. Intoxication with antipsychotic drugs;
4. Acute disorders of cerebral circulation;
5. Neurocirculatory dystonia;
6. Cognitive disorders in the background of atherosclerosis;
7. Anxiety states of moderate severity against a background of neurological disorders;
8. Acute purulent-inflammatory pathologies of the abdominal cavity.

Contraindications

Before starting therapy with the drug should always consult with your doctor. The instructions indicate the following contraindications for use:

1. Pregnancy and lactation;
2. Individual hypersensitivity to the constituents of the drug;
3. Pronounced violations of the liver, acute and chronic hepatic insufficiency;
4. Disturbances in kidney function, acute and chronic renal failure;
5. Age under 18 years (due to lack of clinical experience of use and data on the safety of the drug on the child's body).

Use in pregnancy and lactation

Mexipurum is contraindicated in pregnant and lactating women, since safety and the possibility of its use in this category of patients have not been adequately studied.

Dosage and route of administration

The instructions for use indicate that Mexipram tablets are administered orally. The therapeutic dose and duration of treatment are determined by the patient's sensitivity to the drug.

• At the beginning of treatment the drug is prescribed in a dose of 250-500 mg, the average daily dose is 250-500 mg, the maximum daily dose is 800 mg. The daily dose is divided into 2-3 doses during the day.

For treatment of anxiety disorders, vegetative-vascular dystonia and cognitive impairment, the drug is used for 2-6 weeks.

When cupping an alcohol withdrawal syndrome, the duration of use is 5-7 days.

Course therapy Mexiprim is completed gradually, reducing the dose for 2-3 days.

Solution - instruction

Mexipurum is given in / m or in / in (jet or drip). To prepare a solution for infusion, the drug should be diluted with an isotonic sodium chloride solution.

• Doses are selected individually depending on the pathology and severity of the patient's condition. The initial dose is 50-100 mg 1-3 times / day. In the future, it is possible to increase the dose to obtain a therapeutic effect. The maximum daily dose is 800 mg.

Jet Miksiprim injected slowly, for 5-7 minutes, drip - at a speed of 40-60 drops / min.

1. In acute intoxication with antipsychotic drugs, the drug is administered IV in a dose of 50-300 mg / day for 7-14 days.
2. With mild cognitive impairment in elderly patients and with anxiety disorders, the drug is used in / m in a daily dose of 100-300 mg for 14-30 days.
3. In the treatment of acute disorders of cerebral circulation, Mexiprin is used in a complex therapy in the first 2-4 days IV drip in a dose of 200-300 mg once / day, then in / m at 100 mg 3 times / day. The duration of treatment is 10-14 days.
4. With an abstinence alcoholic syndrome, Mexiprine is administered at a dose of 100-200 mg IM 2-3 times a day, or in / in drip 1-2 times / day for 5-7 days.
5. With discirculatory encephalopathy in the phase of decompensation, Mexiprine should be given intravenously or intravenously in a dose of 100 mg 2-3 times / day for 14 days. Then the drug is given in / m at 100 mg / day for the next 2 weeks. For the course of prophylaxis of dyscirculatory encephalopathy the drug is administered in / m at a dose of 100 mg 2 times / day for 10-14 days.

Side effects

In rare cases, when Mexiprim is used, the following side effects occur: dryness of the oral mucosa, nausea, allergic reactions, increased drowsiness.

Overdose

Symptoms: sleep disturbance (insomnia, in some cases - drowsiness).

Treatment, as a rule, is not required, the symptoms disappear on their own within 24 hours. In severe cases with insomnia, it is recommended to take nitrazepam 10 mg, oxazepam 10 mg or diazepam 5 mg.

Disintoxication therapy is also used.

special instructions

During the treatment period, care must be taken when driving vehicles and engaging in other potentially Dangerous activities that require increased concentration and speed of the psychomotor reaction.

Drug Interactions

With simultaneous use, Mexiprim enhances the action of anxiolytics from the benzodiazepine group, antiparkinsonian (levodopa) and anticonvulsants (carbamazepine).

Mexiprim reduces the toxic effects of ethanol.

Reviews

We picked up some reviews of people taking the drug Mexuprem:

1. Vitaliy. After the accident, I was diagnosed with a craniocerebral injury. I lay in the hospital for a long time. To restore the efficiency of the brain, for a long time I put a dropper with Mexiprim. He helped, but weakly. The doctors had to revise the treatment plan towards a stronger drug. I still have therapy, I will hope that it will help.
2. Olga. To me ball it is appointed or nominated meksiprim in a vein on 2 cube. + sodium chloride. At night Taligia 0.5 tab. For 4 days I began to swing in the sides. On the 5th day they took me to the ambulance. Squeezed chest in the ring.
3. Alexander. I left for drinking after I got fired from work. Soon without a bottle, I could not imagine my life, but my wife managed to persuade me to undergo treatment in the hospital. To stop the withdrawal symptoms, I was given a dropper with Mexiprem solution. Literally for a couple of days I came to myself, normal health returned to me, my headaches went away.

Analogues

It is possible to replace Mexime with other drugs that coincide with it on the active element or the manifested therapeutic effect. The analogs of the medicine are:

1. Mexidol, Mexident - original preparations with the same composition;
2. Mexicor - contains the active substance of oxymethylethylpyridine succinate, has similar effects;
3. Cerekard is a generic from the group of hydroxypyridin succinates;
4. Armadin, Medomexi - solutions with the ethylmethyl hydroxypyridine component succinate;
5. Methostabil, Mexipridol, Mexicin - antioxidant analogues with membrane-stabilizing, nootropic, cerebroprotective, adaptogenic, anxiolytic actions.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Store in a dark, dry place out of the reach of children, at a temperature not exceeding 20 ° C (solution for injection) or not more than 30 ° C (tablets).

Shelf life: tablets - 5 years; solution - 3 years.

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