Cinaphan Ointment

Sinaflane is a medicinal product for external use. It is a glucocorticosteroid.

It has anti-inflammatory, antiallergic, antipruritic and antiexudative action. Reduces and eliminates manifestations of inflammatory skin reaction. The mechanism of action of glucocorticoid ointments is based on suppression of the synthesis of mediators of the inflammatory process of prostaglandins.

Absorption of the drug occurs more intensively in the case of treatment of children, applying to large areas of the skin, with regular application, application to the skin of the face or damaged skin.

Clinical and pharmacological group

GCS for external use.

Terms of sale from pharmacies

It is possible to buy under the prescription of the doctor.

Price

How much does Sinaflan ointment in pharmacies cost? The average price is at the level of55 rubles.

Composition and form of release

Sinaphlane is available in the form of an ointment for external use, which has a light yellow or yellow color (10 g or 15 g in polyethylene laminate or aluminum tubes, in a cardboard bundle one tube).

Composition per 1 g of ointment:

• active ingredient: synaflan (fluocinolone acetonide) 5 mg;
• auxiliary components: lanolin, ceresin, propylene glycol, petroleum jelly.

Is it a hormonal drug or not?

pharmachologic effect

In the process of treating Sinaphalus, people often ask whether this hormonal ointment is or not. For the answer, just once again refer to the composition. The active component, fluocinol acetonide, is a synthetic glucocorticoid. The use of such a substance leads to inhibition of protein and collagen production. It affects the immune system.

This means that the ointment described is a hormonal agent. A direct effect on the skin leads to the fact that neutrophils, a special kind of granulocyte leukocytes, accumulate in it less. Reducing their number leads to:

1. Less production of pathological fluids,
2. Less penetration into the skin of harmful substances,
3. A slower movement of cells capable of digesting bacteria and necrotic particles.

All this causes the effect of the ointment on itching, burning, inflammation and allergic reactions. After Sinaphlan is absorbed into the skin, it enters the capillaries, and then into the blood. Here, the substances bind to the plasma and gradually reach the liver, where the metabolic processes begin. Ultimately, the components are removed from the body with the help of kidneys.

Indications for use

The spectrum of the drug is limited. It is prescribed as an anti-inflammatory, anti-allergic and antipruritic drug. According to the indications for the use of ointment Sinaflan - skin diseases of a non-microbial nature:

• hives;
• neurodermatitis;
• insect bites;
• eczema;
• psoriasis;
• atopic and seborrheic dermatitis;
• red flat lichen;
• lupus;
• itching;
• intertrigo;
• external otitis media.

Contraindications

It is forbidden to use ointment or liniment in such cases;

• anogenital itching;
• skin infections;
• skin tumors;
• melanoma, xanthoma, skin cancer, atheroma, nevus, hemangioma, sarcoma;
• trophic ulcers of the lower leg, which are associated with varicose veins;
• open wounds at the site of application;
• increased sensitivity to components;
• manifestations of syphilis on the skin;
• lupus;
• rash of "diaper" type;
• rosacea;
• large plaques of psoriatic type;
• stomach ulcer in acute phase;
• pregnancy;
• lactation;
• age to 2 years.

With special care use girls at the puberty stage.

Intended use for pregnancy and lactation

It is forbidden to use during pregnancy and lactation, as there is not enough research on the effect of the drug on the baby's body.

Dosage and route of administration

As indicated in the instructions for use, Sinaphlan ointment is prescribed only for adults and children over 2 years of age, use externally.

1. On the previously wiped with a tampon moistened with antiseptic liquid, the skin is applied a small amount of the drug 2-4 times a day and lightly rubbed.
2. The duration of treatment depends on the nature of the disease and is usually 5-10 days, with a long course of the disease to 25 days.

With limited lesions to enhance the effect of ointment can be used for occlusive dressing. It is not allowed to apply more than 2 g of ointment per day to the bandage. Ointment is preferable to use in dry forms of dermatoses.

Side effect

Treatment with the drug is successful. The use of the drug for a sufficiently long time can provoke a repeated infectious lesions of the skin, as well as the development of various atrophic changes of the affected sites. In the event of such complications, antimicrobial agents should be started without stopping the use of Sinaflana.

The drug can cause the following side effects: hirsutism, skin atrophy, telangiectasia, hypertrichosis and perioral dermatitis. In the process of using Sinaphlana in treating common acne, the patient may experience an exacerbation of the disease.

Overdose

With prolonged use of the drug in large areas of the body, the general clinical signs of an overdose develop:

• disorders in the work of the organs of the endocrine system;
• the appearance of unwanted hair on the body;
• adrenal insufficiency.

If these symptoms appear, discontinue drug treatment and consult a doctor. As a rule, no special treatment is required, all the negative symptoms disappear on their own after the removal of the ointment.

special instructions

Use with caution in individuals with existing atrophic skin changes, especially in the elderly.

In patients with ordinary or rosacea, treatment may aggravate the disease. To prevent local infectious complications, it is recommended to appoint in combination with antimicrobial agents.

Apply only short courses on small areas of the skin. The drug should not be applied to the face. Avoid contact with eyes. Duration of use in children should not exceed 5 days. It is recommended to wear loose clothes during treatment.

Interaction with other drugs

When using the drug, it is necessary to take into account the interaction with other drugs:

1. Compatible with antimicrobial drugs.
2. Diuretics (except potassium-sparing) increase the risk of hypokalemia.
3. Reduces the activity of antihypertensive, diuretic, antiarrhythmic drugs, potassium preparations.
4. During treatment with glucocorticosteroids, vaccination and immunization should not be carried out, due to the immunosuppressive effect of the drug.

Reviews

We offer you to read reviews of people who used Sinaflan Ointment:

1. Elena. My son (, years) had allergic dermatitis all over his body. Spoiled six months, even the hormone pricked, so he could sleep at night without itching. Then another dermatologist prescribed Sinaflan ointment. There were improvements in just two applications. Until now, with any rashes, we use only this ointment.
2. Lera. Sinaflane is slow, at least in my case - I have psoriasis of the scalp. I did not use it anymore and the doctor prescribed flucinir for me, that's probably the most effective tool. I, at least, began to forget that I have some health problems, crusts began to depart, the scalp is renewed.
3. Julia. To me 24 and from 5 years I am excruciated from a neurodermite. As a child, rashes were on his hands, on his face and under his knees. To me that only did not write out and all hormonal. Good in this little. Her grandmother has psoriasis and she only uses "Sinaflan". First, the price is attractive and secondly, it actually helps. During periods of exacerbation, my skin is cracked to the blood, my fingers do not bend and only Sinaflan helps. Of course, they should not get involved, but in periods of deterioration without it, nowhere. So, with neurodermatitis and psoriasis, he fights well. Until the end of the disease does not go away, but the inflammation relieves.

Analogues

Structural analogs for the active substance:

• Symmetrad;
• Sinalar;
• Sinaflana ointment, 25%;
• The Synoderm;
• Flukort;
• Flukort C;
• Fluocinolone acetonide;
• Flucinar;
• Ezacinone.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

Keep out of the reach of children at temperatures no higher than 20 ° C.

Shelf life - 5 years.

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