Augmentin in suspension form: instruction manual for children

Augmentin is a combined preparation of the penicillin group of synthetic broad-spectrum antibiotics.

Designed to treat adults and children. As a part of augmentin - active substances amoxicillin trihydrate and potassium clavulanate (clavulanic acid).

The form of augmentin - tablets, syrup, powder for injection, a dry substance for the preparation of suspensions. For the treatment of children under 12 years of age, the syrup and suspension are intended. This form of the drug is easily tolerated even by the smallest patients. However, when taking it is necessary to be careful, since there is a risk of allergic reactions.

On this page you will find all information about Augmentin: full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Augmentin in the form of a suspension. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Antibiotic of a broad-spectrum penicillin group with a beta-lactamase inhibitor.

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Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does an Augmentin suspension cost? The average price in pharmacies is at the level of:

Augmentin powder for the preparation of the suspension 125 / 3, 5 - 118 - 161 rubles;
Augmentin powder for the preparation of the suspension 200 / 28.5 - 126 - 169 rubles;
Augmentin powder for the preparation of the suspension 400/57 - 240 - 291 ruble;
Augmentin EU powder for the preparation of the suspension 600 / 42.9 - 387 - 469 rubles;

Form of issue and composition

The medication consists of:

Amoxicillin (it is represented by trihydrate);
Clavulanic acid (it is represented in the form of potassium salt).

Produced in different forms:

Powder. It is intended for the manufacture of an oral suspension. The following auxiliary substances are used: dry flavors (orange, "Light treacle", raspberry), acid amber, silicon dioxide colloid, xanthan gum, hydroxypropylmethylcellulose, aspartame. Powder is contained inside the vials. The bottle is placed in a package made of cardboard.
Pills. At their creation, the following substances were used: silicon dioxide (colloidal anhydrous), sodium starch glycolate, titanium dioxide, cellulose (microcrystalline), dimethicone 500, magnesium stearate, macrogol, hypromellose (5, 15 cps). Packed in 7, 10 tablets per blister. Inside the pack of such blisters (made of foil) there is a pair.

Powder intended for the manufacture of a suspension is available in the United Kingdom (SmithKline Beecham Pharmaceuticals).

Pharmacological effect

The bacteriolytic effect is noted. The drug exhibits activity to aerobic / anaerobic Gram-positive, aerobic Gram-negative microorganisms. It is very effective against strains that are capable of producing beta-lactamase. Under the influence of clavulanic acid, the resistance of amoxicillin to the effect of a substance such as beta-lactamase is enhanced. In this case, the effect of this substance is broadened.

The drug is active against:

Legionella;
Yersinia enterocolitica;
Streptococcus pneumoniae;
Fusobacterium;
Bordetella pertussis;
Peptococcus spp .;
Bacillus anthracis;
Peptostreptococcus spp .;
Enterococcus faecium;
Streptococcus agalactiae;
Vibrio cholerae;
Listeria monocytogenes;
Borrelia burgdorferi;
Moraxella catarrhalis;
Streptococcus;
Proteus mirabilis;
Peptococcus spp .;
Leptospira icterohaemorrhagiae;
Streptococcus pyogenes;
Neisseria meningitidis;
Treponema pallidum;
Helicobacter pylori;
Brucella spp .;
Streptococcus viridans;
Gardnerella vaginalis;
Haemophilus influenza.

When prescribing a medicine to a child, the doctor must calculate the required amount of suspension for him.

Indications for use

Augmentin is prescribed for bacterial infections caused by microorganisms that show sensitivity to the antibiotic:

infection of bones and joints: osteomyelitis;
odontogenic infections: periodontitis, odontogenic maxillary sinusitis, severe dental abscesses;
infection of the skin, soft tissues;
respiratory tract infections: bronchitis, lobar bronchopneumonia, empyema, lung abscess;
infections of the genitourinary system: cystitis, urethritis, pyelonephritis, abortive sepsis, syphilis, gonorrhea, infections of the pelvic organs;
infections that have arisen as a complication after surgery: peritonitis.

The same medicament is used in therapy, prevention of infectious complications that may occur at operations on organs GASTROINTESTINAL TRACT, area of a neck, a head, a basin, kidneys, joints, heart, bile ducts.

Contraindications

All dosage forms of Augmentinare contraindicated for use in the presence of the following conditions or diseases in a person:

An allergic reaction or hypersensitivity to amoxicillin, clavulanic acid, or antibiotics from the penicillin or cephalosporin group;
The development of jaundice and violations of liver function in the past against the use of drugs containing amoxicillin and clavulanic acid.

Some dosage forms of Augmentinin addition to the above, have the following additional contraindications:

1.Suspension 125 / 31.25:

Phenylketonuria.

2.Suspensions 200 / 28.5 and 400/57:

Phenylketonuria;
Creatinine clearance less than 30 ml / min;
The age is less than 3 months.

3.Tablets of all dosages (250/125, 500/125 and 875/125):

Age under 12 years of age or body weight less than 40 kg;
Creatinine clearance less than 30 ml / min (only for tablets 875/125).

Instructions for use

Children younger than 12 years old or having a body weight of less than 40 kg should take Augmentin only in the form of a suspension. In this case, babies younger than 3 months can only be given a suspension with a dosage of 125 / 31.25 mg. Children older than 3 months of age are allowed to use suspensions with any dosages of active ingredients. It is because the Augmentin suspension is intended for children that it is often called simply "children's Augmentin" without indicating the dosage form (suspension). Dosages of the suspension are calculated individually based on the age and body weight of the child.

The instructions for use indicate that the desired amount of the finished suspension (solution) is measured by a measuring cup or syringe. To take the medicine for children, you can mix the suspension with water, in a ratio of one to one, but only after the required dosage is detected.

In order to reduce the unpleasant sensations and side effects from the gastrointestinal tract, it is recommended to take pills and a suspension at the beginning of the meal. However, if this is impossible for some reason, the tablets can be taken at any time with respect to food, since the food does not have a significant effect on the effects of the drug.
Reception of tablets and suspensions, as well as intravenous administration of Augmentin solution should be performed at regular intervals. For example, if you need to take the drug twice a day, you should maintain the same 12-hour interval between doses. If you need to take Augmentin 3 times a day, you should do this every 8 hours, trying to strictly observe this interval, etc.

To calculate the amount of the drug, the following norms should be used:

Suspension 200 mg.

Up to one year, weight from 2 to 5 kg. - , - , ml 2 times a day;
From 1 year to 5 years, weight from 6 to 9 kg - 5 ml 2 times a day.

Suspension 400 mg.

Children from one year to 5 years, weight from 10 to 18 kg - 5 ml 2 times a day;
From 6 to 9 years, with a weight of 19 to 28 kg-7.5 ml 2 times a day;
Children From 10 to 12 years, weight from 29 to 39 kg - 10 ml twice a day.

Suspension 125 mg.

Up to one year, weight from 2 to 5 kg - , - , ml 3 times a day;
Children from one year to 5 years, weight from 6 to 9 kg - 5 ml z times a day;
From one year to 5 years, weight from 10 to 18 kg - 10 ml 3 times a day;
From 6 to 9 years, weight from 19 to 28 kg - 15 ml 3 times a day;
From 10 to 12 years, weight from 29 to 39 kg - 20 ml 3 times a day.

Dosage of the drug is calculated depending on the type of infection, the stage of the course, the weight and age of the patient. It must be remembered that only the doctor can prescribe the necessary dosage to the patient. When calculating the dosage, it is recommended to take into account only the content of amoxicillin sodium.

Rules for the preparation of suspension

Suspension must be prepared immediately before taking the drug. Preparation rules:

Add 60 ml of boiled water at room temperature to the container with powder, close the lid and shake until the powder is completely dissolved. Further it is necessary to allow the containers to stand for 5 minutes, this allows to ensure complete dissolution of the drug.
Add water to the label on the container with the medicine and shake the bottle again.
For a dose of 125 mg / 31.25 mg, 92 ml of water will be required; For a dose of 200 mg / 28.5 mg and 400 mg / 57 mg, 64 ml of water is required.

The container with the medicine must be shaken thoroughly before each use. In order to ensure accurate dosage of the drug, it is recommended to use a measuring cap, which is included in the kit. The measuring cap must be thoroughly cleaned after each use.

Shelf life of the finished suspension - no more than 1 week in the refrigerator. Suspension should not be frozen.

For patients younger than 2 years of age, the finished single dose of the drug can be diluted with boiled water 1: 1.

Side effects

An antibiotic is considered safe for the body of children. The drug was tested for many years, due to this, the mechanism of its action has been thoroughly studied. Naturally, side effects may appear, but the probability of their occurrence is rather low.

From the side of the digestive system, such negative reactions can occur: vomiting, nausea, diarrhea. When taking an antibiotic, diarrhea is a common side symptom. When using the suspension, the color of the enamel on the child's teeth can change, this does not pose a great danger.
In certain cases, there may be various allergic reactions. Among them: anaphylactic shock, dermatitis, vasculitis, Stevens-Johnson's disease. In certain cases, an allergic rash, erythema, urticaria develops. The child may have severe pain in the head, dizziness.

A complete list of side effects of Augmentin for children can be found in the instructions for the drug. And also the instruction for use contains a complete list of recommendations and dosages, as it is necessary to conduct a course of antibiotic treatment.

To protect the child's body from these undesirable phenomena, it is necessary to strictly observe the dosage of the drug prescribed by a qualified specialist.

Overdose

Overdose manifests itself by dehydration, disruption of the digestive tract, violation of the concentration in the blood of electrolytes.

In this case, symptomatic therapy, which maintains the condition of the baby's internal organs, is shown. To avoid it, you must follow the instructions strictly, do not exceed the dose of the drug.

Drug Interactions

When administered with anticoagulants (indirect), the effectiveness of these drugs will increase.
Joint use with antacids, laxatives or glucosamine worsens the absorption of amoxicillin.
The suspension can be used together with nitrofurans, for example, Enterofuril.
Do not give the baby Augmentin with allopurinol, since this combination can trigger skin allergy.
The drug is not prescribed together with methotrexate, since penicillins increase its toxicity.
With simultaneous administration with macrolides (for example, with a suspension of Sumamed or Azitrox), the action of Augmentin will be weaker. The same effect is observed when combined with tetracyclines, sulfonamides, lincosamides and chloramphenicol.

Reviews

Most of the parents' feedback about the suspension of Augmentin is positive. Moms note that such an antibiotic helps cope with many infections and is tolerated by most children well. They confirm that the treatment starts to act quickly at a high temperature, a cough and other symptoms of infection. Within a few days after the onset of admission, the child's condition improves.

In negative reviews complain about the side effects of the drug, for example, nausea or diarrhea. Pediatricians, among whom Komarovsky, respond about this antibacterial agent mostly well, However, they emphasize the fact that the appointment of a child such a suspension should only a doctor.

Analogues

Among the analogs that can be assigned to children, there are:

Amoxiclav;
Femoclave of Solutab;
Ecoclave.

Before using analogues, consult your doctor.

Storage conditions and shelf life

It is recommended to store the package containing the medicine in a corner where children will not get it. It is necessary to select a dry place, the temperature in it should not be above 250C. For 7 - 10 days, you can store the finished suspension at a temperature of 2 - 8 degrees. A solution intended for intravenous administration should be used immediately after preparation.