Pimafukort - a tool for external use with antibacterial, antifungal and anti-inflammatory activity. It is often used to combat infectious and inflammatory skin diseases.
The composition of the drug includes antibiotic neomycin, antifungal agent natamycin and glucocorticosteroid hydrocortisone.
Such "elegant" composition of the drug, the ingredients of which so successfully complement each other, makes Pimafukort a very popular drug in dermatological practice.
Clinical and pharmacological group
The drug with antibacterial, antifungal and anti-inflammatory effect for external use.
Conditions of leave from pharmacies
Released without a doctor's prescription.
Price list
How much does Pimafukort cost in pharmacies? The average price is at the level of600 rubles.
Form of issue and composition
Pimafukort is produced in two dosage forms for external use: cream and ointment.
1 g of cream contains active ingredients:
- 10 mg of natamycin;
- 3.5 thousand ED neomycin;
- 10 mg of micronized hydrocortisone.
Additionally, the composition of the cream includes auxiliary components: sodium citrate, emulsifier F, cetyl ether wax, macrogol stearate, propyl parahydroxybenzoate, sorbitan stearate, methyl parahydroxybenzoate, purified water.
Cream Pimafukort produce aluminum or plastic tubes of 15 grams, 1 tube in a cardboard box.
1 g of ointment contains active substances:
- 10 mg of natamycin;
- 3.5 thousand ED neomycin;
- 10 mg of micronized hydrocortisone.
Additionally, the cream contains an auxiliary component - PE ointment base.
Pimafukort ointment is made of aluminum or plastic tubes of 15 grams, 1 tube each in a cardboard box.
Cream and ointment Pimafukort - what's the difference?
The composition of the active components, the concentration is no different. They act equally effectively. The difference in the additional components that affect the suction speed.
Ointment in its composition contains only active substances, wax, paraffin. A thick consistency allows the agent to stay on the skin longer. The active components enter the tissue more slowly, the therapeutic effect is prolonged. It is recommended to use ointment for adults, with a strong lesion of the skin, under the bandages.
The cream, thanks to its light consistency, absorbs much faster. The therapeutic effect comes instantly, but it keeps less, it is necessary to apply not twice a day, like ointment, but 3-4. Suitable for children's skin, face, it acts better in the acute form of dermatoses.
Pharmacological effect
Ointment Pimafukort is a combined preparation that has antibacterial, anti-inflammatory and antifungal effects, provided by active components of the composition:
- Neomycin is a potent antibiotic belonging to the group of aminoglycosides. It is active against a very wide spectrum of pathogenic bacteria, including E. coli, streptococci, staphylococci, enterococci and Klebsiella.
- Neomycinis an antibiotic from the group of aminoglycolysis with a wide spectrum of activity of a relatively large number of microorganisms, Gram-positive and Gram-negative.
- Hydrocortisone- a chemical analogue of hormones of the adrenals of glucocorticoids. Has a pronounced anti-inflammatory and local vasoconstrictive effect. This allows him to reduce the appearance of itching, redness of the skin, provoked by an infection of bacterial or fungal origin.
When applying the ointment on the skin, neomycin and natamycin are not absorbed into the blood, and hydrocortisone is adsorbed in small amounts. Note that the amount of absorption can increase in case of skin lesions or a strong inflammatory reaction.
Indications for use
The drug of combined action should be used only in the presence of secondary infection. It is impossible to use at an acute stage of allergic manifestations.
Helps Pimafukort with:
- Mycosis - fungal diseases;
- Dermatoses;
- Pyoderma - purulent inflammation caused by fungi, bacteria;
- Complications of fungal infections;
- Otomycosis - inflammation of the external ear caused by pathogens.
Treatment should be started only after consultation with a specialist.
Contraindications
The overwhelming majority of patients perfectly tolerate the treatment with Pimafukort cream.
Contraindications include:
- cutaneous tuberculosis;
- ichthyosis (genetically caused severe skin disease);
- ulcerative and erosive skin lesions;
- acne (acne);
- individual hypersensitivity to one or more of the components of the agent;
- intolerance to other antibiotics from the aminoglycoside group;
- viral skin lesions (antibiotics and fungicides do not affect non-cellular forms of life);
- unhealed wound surfaces in the affected area;
- rosacea (vol. n. «Pink acne).
Use in pregnancy and lactation
When Pimafukort is included in the scheme of conservative treatment of pregnant or lactating women, it is necessary to remember the possible ototoxic effect of neomycin on the developing organism of the child and mother.
It is also not recommended to apply a cream or ointment under the occlusive dressing or use the medicine for a long time, because so you can skip the first occurrence of side effects or undesirable reactions of the therapeutic effect of the drug.
Dosage and route of administration
The instructions for use indicate that adults and children are given the drug on the affected skin 2-4 times / day. Children should be applied to limited areas of the skin and do not use occlusive dressings.
- The drug in the form of cream is recommended for the treatment of acute and subacute dermatoses.
- The preparation in the form of ointment is intended for the therapy of subacute and chronic dermatoses, especially if available severe dryness of the skin, lichenification, or in cases where the occlusal properties of the ointment are necessary.
The duration of treatment is determined individually, taking into account the nature of the disease, the course of treatment usually does not exceed 14 days. In the absence of improvement in children and adults after 14 days should consult a doctor.
Side effects
After applying the ointment, side effects are rare. They are usually reversible and manifest as follows:
- From the side of the organ of vision: it is very rare to increase intraocular pressure, the risk of developing cataracts increases.
- From the skin / subcutaneous tissue: at the beginning of the drug, there may be a slight exacerbation at the site of the lesion, but you should not stop treatment.
- On the part of the endocrine system: adrenocortical suppression due to topical application of corticosteroids, in individual cases are noted in adults, and it is not expected that it may occur during the application of the Pimafucort preparation. The possibility of developing systemic reactions increases when applied to large areas of the skin, the use of an occlusive dressing, the use for a long period, in children.
- Hypersensitivity reactions are possible; contact dermatitis, burning, skin irritation, eczema, dermatitis; skin atrophy, accompanied by thinning of the skin, purpura, telangiectasias, striae; perioral or rosacea-like dermatitis, which can be accompanied by atrophy skin; delayed healing of wounds; a ricochet effect that can be addictive to corticosteroids; hypertrichosis, depigmentation.
The risk of local undesirable effects increases with increasing duration of therapy. The use of an occlusive dressing, the presence of skin folds on the site also increases the risk of adverse reactions. The skin of the scalp, face, and genitalia is particularly prone to local reactions.
Overdose
To date, cases of an overdose of Pimafucort have not been reported. Theoretically, there is a probability of damage to the structures of the middle ear when applying the drug to the skin in the region of the external auditory canal, provided that the integrity of the tympanic membrane is violated.
special instructions
Before you start using the drug, read the special instructions:
- With caution should prescribe the drug to children under the age of 1 year.
- When applying Pimafukorta to the eyelids and periorbital area, there is a risk of increased intraocular pressure, the development of cataracts.
- In the case of prolonged treatment, in the presence of wounds and ulcers, there is a theoretical risk of ototoxic and nephrotoxic action of neomycin.
- If superinfection occurs or the fungal microflora develops excessively, the drug should be discontinued and appropriate measures taken.
- In children, the drug should be administered under the supervision of a doctor. When applying the drug on large surfaces or under occlusive dressings, one must keep in mind the possibility of suppressing the function of the hypothalamic-pituitary-adrenal system.
Drug Interactions
Drug interaction of the drug Pimafukort is not described.
A cross-over hypersensitivity is possible between neomycin and preparations of a similar chemical structure, for example kanamycin, paromomycin, gentamicin, and cross-resistance between neomycin and other antibiotics of the aminoglycoside group.
Reviews
We picked up some reviews of people who used the drug Pimafukort:
- Olga. Mom uses pimafukort at exacerbation of eczema. After the doctor prescribed this remedy, these exacerbations take place in a couple of days, easier and faster than before.
- Larissa. Ointment is good, it is necessary to recognize that it helps, but hormonal all the same, and accordingly it is not very useful for the skin, the doctor with it prescribes me, that remission would last longer and the skin recover. And of course only on the prescription of the doctor and do not exceed the recommended duration of treatment.
- Lydia. It all started with a terrible rash in the child, so as not to risk going to the hospital. They said he had an allergy. They pierced the injections and sent them home. A few days later the rash returned again, went to the dermatologist, she ordered us "Pimafukort." Smeared only redness, a week later everything passed. The only drawback, the skin after it became very dry, so you had to smear with moisturizing creams.
Analogues
There are no analogues. There are preparations containing antibiotics, fungicides and hormones in various combinations.
Such means include:
- Candiderm;
- Gyioxysone;
- Flucinar;
- Dexa-Gentamicin;
- Acriderm;
- Oxycort;
- Canison plus;
- Polcortolone;
- Cortomycetin.
Before using analogues, consult your doctor.
Storage conditions and shelf life
Shelf life Pimafukort is 5 years from the date of manufacture. The drug should be stored in its original packaging, in a dry, dark place inaccessible to children at an ambient temperature of + 25 ° C.
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