Cough Syrup Lazolvan for Children

Syrup Lazolvan for children

Syrup lasolvan is used to treat cough in children of different ages, beginning with birth. It refers to the pharmacological group of mucolytic drugs, that is, thinned phlegm. Instructions for use recommend taking lazolvan syrup for various diseases of the respiratory system, accompanied by a cough with hard-to-recover sputum. In children, it is usually prescribed for tracheitis, bronchitis, pneumonia, bronchial asthma, cystic fibrosis. In adults, in addition, it can be successfully used in the treatment of chronic obstructive pulmonary disease, bronchiectasis.

Lazolvan is the trade name of the medicine. The active substance in its composition is ambroxol. The syrup is a practically transparent liquid, moderately viscous, with a fruity smell.There are regular and special children's syrup lazolvan.They differ in the content of the active substance.

pharmachologic effect

The drug acts in three ways:

1. Strengthens the secretion in the bronchi of the contents.
2. It breaks the connection between the molecules of sputum and thus dilutes it.
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3. Strengthens the process of excretion of sputum from the respiratory tract (the so-called mucociliary transport).

Contraindications

Do not take lazolvan syrup with an allergic reaction to ambroxol or excipients (hydroxyethylcellulose, sorbitol, glycerol, benzoic acid, propylene glycol, tartaric acid, raspberry flavoring).

It is not recommended to take this medication in the first trimester of pregnancy, as well as during lactation. Renal and liver failure are also contraindications for taking the drug without consulting a doctor.

Dosage

The syrup is taken internally. The package includes a measuring cup, with which it is convenient to measure the required volume of medicine.

Children from birth to 2 years are prescribed on, ml 2 times a day, children from 2 to 6 years - on, ml 3 times a day. Patients from 6 to 12 years should take 5 ml 2-3 times a day, and adolescents over 12 years and adults - 10 ml of syrup 3 times a day.

At a dosage of 30 mg / 5 ml, the volume should be reduced by half.

The syrup is taken regardless of food.

Side effects

Frequent side effects, occurring in 1-10% of patients, are: nausea, a violation of taste sensations, a decrease in the sensitivity of the mucous membrane of the mouth and pharynx.

More rarely (up to 1% of cases) develops abdominal pain, vomiting, diarrhea, dry mouth.

Allergic reaction to lazolvan - a rare phenomenon. It can manifest as urticaria, angioedema, or even anaphylactic shock.

Overdose

Overdose of the drug may be caused by accidental drug use. Therefore, it is very important to keep the bottle of syrup out of the reach of children. There are symptoms similar to the side effects of the medication - nausea, vomiting, diarrhea, abdominal pain. There are no distinctive symptoms of an overdose of lazolvan.

Treatment includes vomiting, gastric lavage (if no more than 2 hours have passed after taking the medicine). Sometimes it is necessary to carry out and symptomatic treatment - the elimination of nausea and vomiting, the removal of pain.

Interaction with other drugs

During the use of lazolvan, penetration into the bronchial secretion of certain antibiotics, for example, erythromycin, amoxicillin, cefuroxime, increases.

Do not use lasolvan medications and cough suppressants (terpinkod and others) at the same time. Joint use of such drugs is not only ineffective, but can lead to sputum stagnation in the lungs and the development of pneumonia.

One of the components of the syrup - sorbitol - sometimes causes a slight laxative effect.

Form of release and storage conditions

In 5 ml of syrup contains 15 mg of ambroxol (respectively in 1 ml - 6 mg of the active substance). At the same time on the package there is a mark "Children's". If there is no such mark, then the dosage is 30 mg / 5 ml (ie 6 mg / ml).

The drug is available in glass bottles made of amber or brown glass. The cap has a so-called first opening control. On the cap is put a measuring cup with risks 3, 5 ml.

Keep the medicine in a cool place, do not allow heating above 30 degrees. The shelf life of the syrup for children is 3 years, the usual syrup is 5 years.

The drug is produced in the Greek branch of the German company Boehringer Ingelheim.

ingalin.ru

Children syrup "Lazolvan reviews, prices, instruction. "Lazolvan" (baby syrup): the price

A child's cough is a common phenomenon. Its cause is a variety of colds, such as bronchitis, influenza and others. Cough delivers anguish and discomfort to the baby, so treatment can not be avoided.

With such a problem, the child first needs to be shown to a doctor who will listen to him. In the event that viscous mucus has accumulated in the bronchi, which the child is not able to cough up, the pediatrician can prescribe the drug "Lazolvan" (syrup for children). The instruction, price, composition, indications and contraindications will be described in this article.

Composition and properties of medicament

The drug is part of the pharmacological group of mucolytic drugs, that is, drugs that dilute sputum. The children's syrup "Lazolvan" is produced in the form of almost transparent liquid, moderately viscous, with a fruity aroma. The main active substance of the drug is ambroxol hydrochloride, which stimulates ciliary activity and the formation of pulmonary surfactant. In other words, it activates the production of mucus in the airways, facilitates its separation and reduces cough. Ambroxol is absorbed into the blood quickly enough, so the therapeutic effect is noticeable after a short period of time. In the interval from half an hour to three hours after using the drug, the concentration of the active component in the blood reaches its maximum. A significant amount of ambroxol is concentrated in the area of ​​drug exposure - in the lungs. The main advantage of the drug is that it is quickly excreted from the body and does not accumulate in the tissues.

Indications for use

With ailments of the lower respiratory tract, accompanied by viscous sputum, the drug "Lazolvan" (syrup for children) is prescribed. Reviews of doctors and parents confirm its effectiveness in such diseases as:

• bronchitis;

• bronchial asthma with hard-to-separate sputum;

• pneumonia;

• bronchiectatic disease.

This medication can also be used to stimulate intrauterine growth of the lungs in the fetus, if there is the threat of premature birth or need artificial delivery at the time between the 28th and 34th weeks pregnancy. In addition, the drug "Lazolvan" is used for the prevention and therapy of a condition such as postpartum respiratory distress syndrome in newborns and premature babies.

Children's Lazolvan (syrup): instructions for use

The medicine is intended for oral administration. They produce medicament in vials made of brown or amber glass. The cap is equipped with a so-called first opening control. Packing is equipped with a special measuring cup, by means of which it is convenient to measure the required amount of the medicine.

How to take Lazolvan (baby syrup)? According to the instructions, the preparation is used according to the following scheme:

• from birth to 2 years - 5 ml for 24 hours (take for 2 times);

• from 2 to 6 years ml for 24 hours (take 3 times);

• from 6 to 12 years - 10-15 ml for 24 hours (take 2-3 times);

• after 12 years - 30 ml for 24 hours (take 3 times).

Take syrup for children "Lazolvan" regardless of food intake.

Contraindications for use

Cough syrup "Lazolvan" (for children) is contraindicated for individual hypersensitivity to ambroscoli or other components of the drug.

Side effect of the drug

In rare cases, adverse events may occur after taking such a drug as a children's Lazolvan (syrup). The instructions attached to the medication usually contain this information.

The side effects of the medicine in question are manifested by a violation of taste sensations, nausea, a decrease in the sensitivity of the oral mucosa and throat, such phenomena occur in 1-10% of cases. Significantly less (less than 1% of cases) there is pain in the abdomen, diarrhea, vomiting, dry mouth.

Allergic reactions that arise due to sensitivity to the components of the drug "Lazolvan develop are rare and are manifested by symptoms such as angioedema, hives, anaphylactic shock (very rarely).

Drug Interactions

The use of the drug "Lazolvan" enhances the penetration of certain antibiotics into bronchial secretions, for example, such as "Erythromycin "Cefuroxime "Amoxicillin".

It is undesirable to simultaneously use the syrup "Lazolvan" for children and drugs that depress cough (for example, "Terpinkod"). Joint reception of such medications not only will not give a positive result, but it can also provoke sputum stasis in the lungs and the development of pneumonia.

The drug "Lazolvan" (baby syrup): the price

The cost of such a medication depends on several factors: the costs of renting a room, transportation, the price policy of a pharmacy and so on. Practically in every pharmacy you can buy this drug. However, there are a lot of counterfeit goods on the pharmaceutical market today, so you should refrain from buying too cheap a medicine "Lazolvan" (baby syrup). The price of a medicine in Russia averages 250-300 rubles per 100 ml bottle.

Other forms of release

In addition to the syrup, the drug "Lazolvan" is released in the form of drops, tablets and solution for injection and inhalation. Let's consider the details of the release form.

Drops

Drops of "Lazolvan" are used to prepare a solution, which is used according to the following scheme:

• from 0 to 2 years - 50 drops for 24 hours (take for 2 times);

• from 2 to 6 years - 75 drops throughout the day (take 3 times);

• after 6 years - 150 drops for 24 hours (take 3 times).

The indicated doses of the drug are diluted in 5 - 75 ml of water.

Pills

For children after six years, the drug "Lazolvan" is recommended to use in the form of tablets. This form of medication is taken in the same way as syrup - three times a day. However, for children under six years of age, it is not recommended to use them. The reason for this is simple - it is impossible to establish the exact dosage.

To prevent a decrease in the effectiveness of the drug and the occurrence of allergic reactions after the first three days of therapy, it is recommended to reduce the number of receptions to two. Based on the child's age, Lazolvan tablets are used as follows:

• from 6 to 12 years - 30-45 mg throughout the day (take 2 or 3 times);

• after 12 years - 60-90 mg throughout the day (take 2 or 3 times).

Solution for injection and inhalation

This form of medicine "Lazolvan" is used much less often than tablets or syrup. For inhalations the following doses of the drug are used:

• from 0 to 2 years - 15 ml for 24 hours (take for 2 times);

• from 2 to 6 years - 30 ml during the day (take for 2 times);

• from 6 years and older - 45 ml for 24 hours (take for 2 times).

Injections "Lazolvan" are administered in the form of drip infusions or intramuscularly. This form has a higher efficacy in comparison with syrup, but the risk of undesirable effects increases proportionally.

The maximum period during which the drug "Lazolvan" is allowed is 7 days. After the indicated time, the use of this medication should be discontinued and consult with your doctor about further treatment.

Terms and conditions of storage

The drug "Lazolvan" should be stored in a cool, inaccessible place for children, the temperature of the air should not exceed 30 ° C. The drug is suitable for three years from the date of manufacture, after the expiry of the specified period, the remnants of the funds must be disposed of.

Conclusion

Any disease of the child always generates a lot of questions from parents about the methods of treatment and the choice of the most effective and safe drug. Syrup "Lazolvan" is a highly effective medicine. But remember! Self-administration and use of medication without prior consultation with a specialist can be very dangerous for health, and sometimes for a child's life.

Take care of yourself and your children! Be healthy!

syl.ru

Instructions for the use of mucus in syrup and tablets

Cough syrup Lazolvan is a popular mucolytic drug that is used in pediatrics and for the treatment of adults. The most commonly prescribed syrup with a dry cough, when it is difficult to withdraw phlegm. Lazolvan is also presented in oral dosage forms with tablets and lozenges and a solution that is used for inhalation.

The active substance dilutes the bronchopulmonary secret and promotes its natural separation. The drug is indicated in the treatment of various diseases of the respiratory system with the clinic with difficultly separated sputum. When it comes to children, the main indications for therapy are: bronchitis, tracheitis, bronchial asthma, pneumonia, cystic fibrosis. Adult medication is prescribed for bronchiectasis, COPD (chronic obstructive pulmonary disease).

The drug belongs to the group of auxiliary therapy.

Farmgroup: Expectorant and mucolytic drug.

Composition, physicochemical properties, price

Lazolvan is produced as two syrups for internal use, one of which (30 mg / 5 ml) is used in adult patients and children from 6 years of age. In the instructions for the use of Lazolvan syrup for children with a dose of 15 mg / 5 ml indicated that it can be administered to children from birth and adults.

Syrup

Syrup 30 mg / 5 ml	Children's syrup 15 mg / 5 ml
Base material	Ambroxol hydrochloride
30 mg	15 mg
Excipients	8.5 mg of benzoic acid, 750 mg of glycerol 85%, hyethelose 10 mg, 5 mg of potassium acesulfame, 1750 mg sorbitol liquid, 12 mg of strawberry-cream flavor, 3 mg of vanilla flavor, 3031.5 mg water.	8.5 mg of benzoic acid, 750 mg of glycerol 85%, hyiethellosis 10 mg, 5 mg of potassium acesulfame, 1750 mg of sorbitol liquid, 11 mg of flavor forest berry, 3047.5 mg of water.
Physicochemical characteristics	Transparent or almost transparent syrup, not having color, slightly viscous, with the aroma of strawberry.	Transparent or almost transparent syrup, without color, slightly viscous, with the aroma of forest berries.
Packaging	A syrup of 100 and 200 ml in vials of darkened glass with a measuring cup, in packs of cardboard.
Appearance
Price	The price of Lazolvan syrup: 250-270 rub.	190-200 rub.

Pills

Pills	Lozenges
Base material	Ambroxol hydrochloride
30 mg	15 mg
Excipients	171 mg of lactose monohydrate, 36 mg of cornstarch dried, 1.8 mg of colloidal silica, 1.2 mg of magnesium stearate.	850 mg acacia gum, 370.4 mg sorbitol, 614.8 mg caryon 83, 10 mg peppermint leaf oil, 2 mg leaf-like eucalyptus leaf oil, 1.8 mg of sodium saccharinate mg of liquid paraffin, 196.6 mg of purified water.
Physicochemical characteristics	White or yellowish tablets of round shape, flat, having beveled edges, with the risk of separation on one side and engraving "67C" and the symbol of the manufacturer on the other side.	Light brown pastilles, round, with peppermint flavor.
Packaging	For 10 tab. in blisters, 2 or 5 blisters in a cardboard box.	For 10 pastes. in the blister pack. In a cardboard bundle for 1, 2 and 4 blisters.
Appearance
Price	№ 20 - 160-200 rubles.	№ 20 - 160-180 rubles.

pharmachologic effect

In multiple medical studies, it was found that ambroxol increases the secretory function of the respiratory tract. The substance accelerates the production of surfactant and activates ciliary activity.

These effects cause an increase in the current and movement of mucus along the respiratory tract. Thus, sputum transport is improved and cough is greatly facilitated.

It was noted that during long-term treatment with Lazolvan (2 and more months) in patients with COPD decreased the number of exacerbations, and also shortened the duration of acute period and duration of treatment antibiotics.

Pharmacokinetics

For all forms of the immediate release preparation, almost complete, rapid absorption with direct dependence on the therapeutic dose in the therapeutic range of concentrations is characteristic.

At internal reception the maximum maintenance of an ambroxol in a blood plasma is noted through, -2 hours. When the therapeutic concentration is reached, binding to plasma proteins reaches a maximum of 90%. The transport of ambroxol from the blood to the tissue with internal reception occurs quickly. The highest concentration of ambroxol is observed in the lung tissue.

About 30% of the administered dose of the drug is exposed to the effect of primary transport by the liver. The predominant isoform taking part in the conversion of ambroxol to dibromoanthranilic acid is CYP3A4. The remainder of ambroxol undergoes liver metabolism, mainly by glucuronidation and partial digestion to the metabolite of dibromantranilic acid and other inactive substances.

T 1/2 is 10 hours. The total clearance varies in the limit of 660 ml / min, with about 83% of the total clearance falling on the kidney clearance.

Clinically significant influence of age and sex characteristics on the pharmacokinetics of ambroxol was not found, therefore, when choosing a dosage, these characteristics are not taken into account.

Indications

The drug is indicated for diseases of the respiratory system of acute and chronic course, which are accompanied by the release of viscous sputum:

• COPD;
• bronchitis acute and chronic;
• pneumonia;
• bronchial asthma;
• bronchiectatic disease.

Contraindications

• Pregnancy (1st trimester);
• Lactation;
• Children under 6 years (syrup 30 mg / 5 ml and lozenges) and up to 18 years (tablets);
• Intolerance to fructose;
• Individual hypersensitivity to ambroxol and other drug substances;
• Lactose intolerance, lactase enzyme deficiency, glucose-galactose malabsorption (for l / p tablets).

Pregnant women in the 2nd and 3rd trimester, people with hepatic or renal insufficiency, the drug is administered with caution.

Ambroxol is proven to penetrate the placental barrier. At the same time, negative (direct or indirect) effect on pregnancy, intrauterine development of the fetus is not established. However, the drug is administered with caution and if the benefit to the woman exceeds the potential risks regarding the effect on the fetus. Ambroxol is also excreted with maternal milk, so do not recommend using the drug in the lactation period.

Dosage

All described forms are intended for oral administration, regardless of food intake. The tablets are washed down with water. The lozenges dissolve in the mouth before dissolving.

Syrup 15 mg / 5 ml:

• children from birth to 2 liters ml twice a day;
• children 2-6 liters ml three times a day;
• children 6-12 l: 5 ml three to two times a day;
• children from 12 l, adults: 10 ml three times a day.

Syrup 30 mg / 5 ml:

• children 6-12 l ml two to three times a day;
• children from 12 l, adults: 5 ml three times a day.

Pills

According to 1 table. (30 mg) three times a day. The dose may be increased to 2 tablets. (60 mg) twice a day.

Pastilles:

• children 6-12 liters: 1 lozenges two to three times a day;
• children from 12 l, adults: 2 lozenges three times a day.

If symptoms persist for more than 4-5 days during Lazolvan treatment, you should consult a doctor.

Side effects

• Digestion system: often nausea, decreased sensitivity in the pharynx and oral cavity, less often - vomiting, dyspepsia, diarrhea, epigastric pain, dry mouth. Rarely, dryness in the throat can be noted.
• Nervous system: often a violation of taste.
• Allergic reactions: rarely such phenomena as hives, rashes, itching, angioedema and other anaphylactic reactions.

Overdose

If therapeutic doses are exceeded, nausea, dyspepsia, vomiting and diarrhea may develop. Treatment is symptomatic.

special instructions

Sorbitol, which is part of the pastilles and syrup, is able to exert a mild laxative effect.

Ambroxol does not affect the central nervous system, so the use of Lazrolvan does not limit the ability to control mechanisms, a car, etc.

Drug Interactions

No significant effect was observed with the interaction of Lazolvan with other drugs. With conscientious use with amoxicillin, cefuroxime and erythromycin, amplification therapeutic effect of the latter, as the penetration of active substances into bronchopulmonary secret.

Lazolvan can not be combined with antitussive drugs, which reduce the excretion of phlegm - there will be an effect that is opposite to the desired one.

Analogues

Analogues of Lazolvan syrup: Ambrohexal, Amprobeene, Ambroxol, Ambrosol, Flavamed, Khaliksol. Bronchorus.

zdravotvet.ru

Lazolvan - instruction

Lazolvan is a mucolytic medicinal product intended for the treatment of inflammatory diseases of the lower and upper paths respiratory system accompanied by the production of sputum and inflammation, which is used to treat diseases associated with wet cough. It has in its composition an active substance - ambroxol hydrochloride, which has an expectorant, secretory and secretionolytic action, based on the normalization of the disturbed ratio of mucous components phlegm. Therefore, this drug is a medicinal product for the treatment of bronchitis, pneumonia, tracheobronchitis and for the comprehensive treatment of bronchial asthma and other chronic lung diseases.

Factumodynamics

The mechanism of action of lazolvana consists in its expressed expectorant, secretory and secretory action in respiratory tract and stimulation of perinatal development of the lungs - increased synthesis, stimulation of secretion and blockage of disintegration surfactant. Also, this drug has a stimulating effect on the cells of the glands of the mucous membrane of respiratory pathways, increasing the secretion of mucosal secretions in bronchi and alveoli, and stimulates ciliary activity. The mechanism of lazolvan action is activation of hydrolyzing enzymes in serous cells of bronchial and alveolar glands, in connection with which there is an increase liberation of Clarke cells by lysosomes, and as a result, the viscosity of the sputum decreases, which leads to an improvement in its isolation, withdrawal and elimination, which leads to cough reduction.

Pharmacokinetics

Lazolvan is well absorbed in the gastrointestinal tract and has a high absorption capacity in all routes of administration. Its optimal concentration in the blood plasma is achieved two hours after admission. The action occurs when taken in tablet form or in the form of a syrup - after 30 minutes, with rectal administration an average of ten minutes to half an hour and depends from the absorption of the active substance in the stomach and intestines, and with the parenteral administration of the drug, its effect comes quickly and lasts up to 10 hours. Lazolvan has good permeability through the placental and blood-brain barrier, and can also be excreted in breast milk. Lazolvan metabolism occurs in the liver, where it forms glucuronic conjugates and dobranthanthranic acid. Lazolvan is excreted from the body mainly by the kidneys.

Indications for the use of Lazavana

Having high efficiency, excellent expectorant, secretory and secretory effects this drug It is used in most respiratory diseases, in which a large amount of viscous sputum is formed, as antitussive.

Indications for its use are:

1. Acute pneumonia;
2. Acute tracheobronchitis, acute obstructive bronchitis, acute bronchitis;
3. Bronchoectatic disease;
4. Chronic bronchitis (on the background of respiratory failure or its absence);
5. Children's infectious diseases complicated by bronchitis and pneumonia;
6. Chronic nasopharyngitis, laryngitis and laryngotracheitis;
7. Bronchial asthma, in which the formation of viscous sputum and the difficulty of its withdrawal;
8. Chronic rhinitis;
9. When sanation of the bronchial tree in the preoperative period and after surgery;
10. Cystic fibrosis of the lungs;
11. Chronic sinusitis;
12. Acute sinusitis of various etiologies.

Method of application of incompetent

This preparation has such forms of release: in the form of tablets, lozenges, solution for inhalation, a syrup for children and a solution for ingestion and is made by the company Boehringer Ingenheim.

The syrup is produced in 100 ml glass vials and containing 15 milligrams of active substance Ambroxol hydrochloride in 5 ml of syrup for children and syrup for adults 30 milligrams of active substance in 5 ml of syrup.

The tableted form of lamnavan is a tablet of 10 pieces in a blister, coated with a shell and containing 30 milligrams of ambroxol.

The solution for ingestion and inhalation contains 15 milligrams of active substance in 2 ml.

Lazolvan pastilles are round, light brown in color and contain 15 milligrams of ambroxol hydrochloride in one lozenge.

Bladder for inhalation

The solution for inhalation and ingestion contains 15 milligrams of active substance in 2 ml.

Inhalation solution is lazolvan, adults and children over six years of age are administered one or two inhalations of 2-3 ml each of a solution of an indigestion once a day, and for children up to the age of six, one or two inhalations of 2 ml of solution one times day.

Inhalation solution of lazolvan is used on any inhalation equipment with the exception of steam inhalers. The drug is mixed in equal proportions with the physiological solution, and to achieve the best humidification of air in the inhaler is heating the inhalation solution to the temperature body. Inhalations are carried out in the mode of normal breathing without deep breaths, which can provoke a cough. Patients with bronchial asthma should be inhaled after taking bronchodilators.

Lazolvan syrup

The syrup consists of an active active ingredient - ambroxol hydrochloride, as well as a number of components that serve to create consistency, give a pleasant taste and aroma. The syrup has a thick consistency, almost colorless, with a pleasant berry taste. It is realized in glass bottles of 100 ml of dark amber glass and contains 15 milligrams Ambroxol hydrochloride in 5 ml of syrup for children and 30 mg of active substance in 5 ml of syrup for adults.
A syrup of 15 milligrams in 5 ml is used in adults and children over the age of twelve - 10 milliliters, which is two tea spoons three times a day, and children from six to twelve years old - 5 milliliters each, which corresponds to one teaspoon two to three times a day day. And children from two to six years - on, milliliter, which corresponds to a half-spoonful three times a day and To children till two years age it is appointed on poljchajnoj spoons two times a day that makes, milliliters.

Syrup lasolvanum containing 30 milligrams of active substance in 5 ml is used only in adults and children after six years in dosages: adults and children over the age of twelve - 5 ml each, which is one teaspoon three times a day day. And to children from six to twelve years old - one, one ml, which corresponds to a half-spoonful two to three times a day.

Lazolvan solution

Lazolvan solution is taken orally in the form of drops and 1 milliliter of the drug corresponds to twenty-five drops. The drug is taken with food and added to fruit juice, tea, water or milk.

Adults at the very beginning of treatment lazolvana solution is prescribed to 4 ml three times daily, children over six years - 2 ml, which corresponds to 50 drops of the solution two or three times a day. For young children from the age of two to six years - 1 ml, which corresponds to 25 drops three times a day, and to children to the age of two - 1 ml, 25 drops, respectively, twice daily.

Lazolvan Tablets

The tableted form of lazolvan is used only in adulthood inside, after eating 30 milligrams, which corresponds to one tablet three times a day, but if necessary, the dose can be increased to 60 milligrams twice day.

Contraindications

Contraindications to the use of mucus are increased individual sensitivity to ambroxol hydrochloride - the active substance of the drug or another component that is part of the drug preparation.

Also, it is contraindicated taking a medication in the early stages of pregnancy.

Specific guidance and interaction with other drugs

Caution this drug should be taken in the second and third trimester of pregnancy and during lactation.

It is not recommended to take the drug with liver or kidney failure.

Lazolvan is not recommended for use with drugs that suppress the cough reflex, containing codeine in its composition. And at the same time, the combined use of lazolvana and antibacterial drugs can potentiate the action of antibiotics, causing their more active therapeutic effect. A good therapeutic effect is the use of mucus in conjunction with mucolytic agents of plant origin.

Side effects

Side effects of lazolvan are allergic reactions with individual hypersensitivity to a medicinal preparation in the form of allergic contact dermatitis, urticaria, angioedema edema. In the case of prolonged uncontrolled use of the drug, nausea, heartburn, gastralgia, or vomiting may occur.

If these symptoms occur, you must stop taking a mucus and seek medical advice from a medical institution.

Overdose

Overdose lazolvana arises in the case of taking the drug at a dose exceeding the permissible, with the use of an adult form of syrup in childhood, with the accumulation of a drug in the body that occurs when its metabolism is disturbed, prolonged admission and impaired excretion from the body in renal pathology, or liver.

Symptoms of lazolvan overdose are nausea, heartburn, gastralgia, vomiting or an allergic reaction in the form of allergic contact dermatitis, hives, angioedema. With severe form, anaphylactic shock can develop.

In cases where a small child drinks a large amount of mucus, it can cause vomiting, nausea, or abdominal pain, so it is necessary to seek medical help, where it is necessary to carry out a child gastric lavage and, if necessary, detoxification therapy.

Also dangerous are situations where when taking a large amount of the drug, both in children and adults, there are allergic reactions in the form of anaphylactic shock, angioedema, which are related to anaphylactic-type reactions and are characterized by rapid or rapid flow. Therefore, when developing them, you urgently need to seek medical help from a medical institution.

Lazolvan for lactation and pregnancy

The intake of this lazolvana during pregnancy is contraindicated in the first three months of pregnancy and is not recommended to pregnant women in the second and third trimester of pregnancy and during the period lactation, as there is always the risk of adverse effects of the drug on the embryo in the early stages or on the developing fetus in the later stages pregnancy. However, lazolvan is a medicinal preparation that is a stimulator of perinatal lung development by increasing synthesis, stimulation secretion and blocking of disintegration of surfactant in case of threat of premature birth or fetal hypotrophy for stimulation of prenatal maturation lungs.

Also, when breastfeeding the baby, the use of lazolvan is not recommended.

Lazolvan for children

Lazolvan is today considered to be one of the most safe and effective drugs for children, which is used from a very early age and has virtually no adverse reactions. For very young children, a convenient infant formula of lazolvan in syrup is used, which is distinguished by a pleasant taste and safety, since it contains no sugar and alcohol. Older children can use pastilles and a solution of lazolvan, as well as syrup with a higher concentration of active substance in the composition.

The distinctive features of this drug for children is that it is able to exert as a mucoregulatory, and mucolytic effect on the mucous membrane of the lower respiratory tract, which contributes to the dilution of viscous stagnant phlegm. As a mucoregulator, lazolvan activates the cilia of the ciliated epithelium and this speeds up and improves the sputum evacuation.
Lazolvan - a drug that actively affects the consistency of sputum, while regulating the ratio of its constituent components, in As a result, the viscosity of the sputum decreases and leads to an improvement in its withdrawal and removal from the respiratory tract of the child, which leads to a decrease cough.

In bronchial diseases, very thick and viscous sputum is often produced, and this fact often complicates the purification of the respiratory system in bronchitis, pneumonia, cystic fibrosis, bronchial asthma and bronchoectatic disease, and lazolvan - dilutes sputum and promotes its fastest withdrawal, and its effect begins in thirty minutes. In addition, lazolvan activates the production of surfactant, which facilitates the removal of mucus from the surface of the bronchi, providing a motor function of the bronchi. Also, this drug has a weak anti-inflammatory effect, reducing the inflammatory response in the tissues of the lower respiratory tract, and has antioxidant qualities. Under the influence of the falcon, more immunoglobulins are produced and this increases the activity of local immunity in the bronchi and lung alveoli.

Lazolvan is also used in pediatrics for the comprehensive treatment of respiratory infections: measles, rubella, mumps, scarlet fever or chickenpox with their complicated course and development of bronchitis in the child or pneumonia.

In pediatric practice, it is used as a syrup, solution for ingestion and inhalation.

A syrup containing 15 milligrams of ambroxol in 5 ml is dosed: toddlers up to two years - twice a day by half-hour a spoonful of syrup, half a spoonful, which corresponds to ml, children from two to six years - three times a day by half a spoon (, ml). And children over twelve years - three times a day for 5 ml, which is one teaspoon.

Syrup lazolvana, which contains 30 milligrams of ambroxol in 5 ml in childhood is used only for children over the age of twelve - 5 ml, which is one teaspoon three times a day. And to children from six to twelve years old - one, one ml, which corresponds to a half-spoonful two to three times a day.

A solution of lazolvan in pediatrics is dosed in drops - children over six years old - 50 drops of solution or 2 milliliters of solution, two to three times daily. Young children between the ages of two and six years -25 drops or 1 milliliter of solution three times a day, and toddlers to two years old - 25 drops or 1 milliliter of solution, twice a day.

Or in the form of inhalation with the help of any inhaler, besides having evaporating properties - steam inhalers.

Practical application of an indigestion for treatment of cough

Lazolvan is a medicinal product, which is an excellent development of the pharmacological company Boehringer Ingenheim, and today it is considered very effective and a popular drug that is widely used in medical practice: pediatrics, therapy and to a lesser extent in otolaryngology, as a drug for cough treatment in children and adults.

Lazolvan in its antitussive effect has excellent efficacy, diluting the mucous secret of the trachea, bronchi, alveoli and thick mucus accumulating in the nasopharynx. This excellent effect occurs due to a change in the structure of the mucopurulent or mucous secretions. The peculiarity of lazolvan is their ability to dilute sputum, do not increase its quantity in lumen of the bronchi or trachea and the absence of negative effects, in contrast to expectorant drugs means.

Lazolvan is widely used in pediatric and therapeutic practices for the treatment of cough that causes inflammatory diseases predominantly in the lower respiratory tract - laryngotracheitis, tracheitis, bronchitis, and pneumonia.

It is prescribed for inflammatory diseases of the lower respiratory tract of infectious and inflammatory genesis, which are accompanied by a pronounced moist cough - acute and chronic tracheobronchitis, chronic nasopharyngitis, laryngitis and laryngotracheitis, acute pneumonia, acute, chronic and obstructive bronchitis.

Lazolvan is also used in the treatment of prolonged inflammatory processes of the respiratory tract, in this case it is the drug of choice for all COPD in the elderly, due to its high efficiency and safety, as well as minimal adverse reactions and a diverse form release.

This drug is very effective in the schemes of complex therapy for bronchial asthma with difficulty in withdrawing sputum, in cystic fibrosis of the lungs, as well as during the sanation of the bronchial tree in the preoperative period and after the operative interference.

Lazolvan is used in otolaryngology for the treatment of acute and chronic inflammatory processes of the paranasal sinuses and the nasal cavity - sinusitis and rhinitis, in which stagnant viscous mucus stagnates and stimulates mucociliary transport.

There are forms of mucus in ampoules for injection. Parenterally, it is administered intramuscularly, subcutaneously or intravenously. This form of the drug is used only for inpatient treatment of patients with pneumonia, complicated bronchitis or severe combined pathology of the bronchopulmonary system. In such cases, the combined use of lazolvana and antibacterial drugs is practiced, which causes a more active therapeutic effect of antibiotics, potentiating their effect. A good effect results in the use of lazolvana in conjunction with mucolytic agents of plant origin - breast-feeding.

In clinical use, the drug has excellent tolerability, even with its long-term use at any age.

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Lazolvan for children

Lazolvan for children is an effective modern cough medicine. This drug has an expectorant effect, dilutes sputum and accelerates its excretion from the lungs and bronchi, softens the cough. Instructions for use asserts that lazolvan can be used from birth. It is used for acute and chronic bronchitis, pneumonia, bronchial asthma, cystic fibrosis, as well as for any infection of the lower respiratory tract of unspecified origin accompanied by a cough.

For treatment in childhood, different dosage forms of this drug are used: tablets, solution for ingestion and inhalation, syrup, and also injection. It is necessary to strictly observe the dosage of the medicine in order to prevent the development of side effects.

There is also a spray in the nose called "Lazolvan Reno". It does not refer to expectorant drugs, but is a vasoconstrictor for the treatment of the common cold. It is produced by the same manufacturer as the usual lazolvan. Lazolvan Reno is contraindicated in patients younger than 6 years. Take it with nasal congestion and runny nose for 1 injection in each nostril up to 4 times a day.

Pills

One tablet of mucus contains 30 mg of active substance - ambroxol. Tablets are white or yellowish in color, flat. They have a separation strip, which allows you to divide the tablet in half to get a dose of 15 mg. After taking the pill, the highest concentration of medication in the tissues is recorded after 2 hours.

Lazolvan tablets prescribed for patients older than 6 years. This is mainly due to the existence of more convenient dosage forms for children. Patients from 6 to 12 years should take half the tablets 2-3 times a day for no more than 5 consecutive days. For adolescents aged 12 years, the recommended dosage is 1 tablet 3 times a day for 2-3 days, then half the tablet 3 times a day for 2-3 more days.

Frozen tablets should be taken after eating, squeezed with a sufficient amount of liquid (water, tea, juice) - not less than 100 ml. Receiving a liquid will help form a liquid sputum, prevent dry mouth.

Solution for ingestion and inhalation

Such a solution contains, mg of ambroxol in 1 ml. It can be used for oral administration since birth.

Children from birth to 2 years are prescribed 1 ml (25 drops of solution) 2 times a day. If the age of the baby is from 2 to 6 years, he can take 1 ml (25 drops) 3 times a day. Patients from 6 to 12 years are given 2 ml (50 drops) 3 times a day, and from 12 years - an "adult" dosage of 4 ml 3 times a day.

The same solution can be used for inhalation. The inhalation route of drug administration is an effective and safe way of treating cough. You need to know that such a solution must be taken with a nebulizer. The steam procedure above the saucepan will be ineffective in this case.

Inhalation through the nebulizer allows the medicine to quickly get on the inflamed mucous membrane and begin to act immediately in the center of the disease. This reduces the risk of side effects.

For the procedure, 2-4 ml of physiological saline is poured into the nebulizer chamber and the required amount of the drug is added. Treatment should be done in a calm environment for 3 minutes. For children, you can purchase a special children's nebulizer in the form of a toy (for example, a locomotive). When bronchial asthma is recommended before inhalation with lazolvanom apply bronchodilator.

Children under 3 years of inhalation through a nebulizer can be held if a small patient is able to breathe properly with this procedure. Usually they are prescribed for children over 3 years old. At the age of 6 years, 2 ml of lazolvan solution are used per 1 inhalation 1 time per day; from 6 to 12 years, you can use 3 ml of the drug 1 or 2 times a day. Teenagers from 12 years of age are usually prescribed 3 ml 2 times a day.

For inhalations through the nebulizer, you can not use a syrup or solution for injection. Such procedures are conducted daily for 4-5 days.

Syrup

Syrup lazolvan - the most popular form of medicine for cough in children.He is prescribed to patients older than 1 year. There is a special "Children's" lazolvan in a dosage of 15 mg in 5 ml (3 mg / ml) with raspberry flavor. A common syrup is also available in a dosage of 30 mg in 5 ml (6 mg / ml) with apricot flavor. He is usually assigned to older children.

Take medicine after eating, squeezed it with a sufficient amount of liquid (water, juice, milk, tea, compote, etc.). The dosages given below correspond to children's syrup (15 mg in 5 ml). Babies from year to 2 years give on, ml on reception 2 times a day. A patient aged 2 to 6 years gets, ml, at the reception 3 times a day. A child from 6 to 12 years can give 5 ml per reception 3 times a day, and from 12 years - 10 ml per reception 3 times a day.

The kit includes a measuring cup, with which it is convenient to dose the medicine.

Injection

Lazolvan for injection can be used in children from birth in the presence of severe lung diseases. In particular, it is prescribed for premature infants to accelerate the maturation of lung tissue in them and to adapt to air as soon as possible. Of course, in this case, the drug is recommended only by a doctor and is administered under strict control of the child's condition.

Dosage for intravenous administration in infants is 10-30 mg per 1 g of body weight per day. At the age of 2 years, appoint, mg of the drug 2 times a day. At the age of 2 to 5 years, the administration of, mg, 3 times a day is possible. A child of 5 years is prescribed 15 mg (1 ampoule solution) 3 times a day, most often intramuscularly.

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Lazolvan for inhalations: instructions for use of the drug

Among the antitussive agents widely used in diseases of the respiratory tract, Lazolvan for inhalation belongs. Getting on the mucous membranes of the bronchi, the drug stimulates the activity of serous cells. The main purpose of inhalation with lazolvanom - the elimination of cough, as a sign of catarrhal, viral or infectious diseases.This drug does not belong to the group of mucolytics, it is endowed with a pronounced secretotomotor, secretolitic and expectorant properties.

Pharmacological properties

In the instruction of an indigestion for inhalations it is indicated that with the regular conduct of a therapeutic procedure an unpleasant symptom of the disease is completely eliminated. This treatment is especially effective in the autumn-spring period, if it is carried out at the initial stage of the disease development.

In case of infection in the upper parts of the respiratory system, dense viscous mucus begins to form in the bronchi, which complicates the process of breathing. If you know how to do inhalation with lazolvanom, you can get rid of bouts of cough in a few days. Carrying out the procedure contributes to the removal of harmful metabolic products - metabolites from the body, thereby speeding up the recovery. Under the influence of Lazolvan, pathogenic microorganisms are destroyed, which also poison the patient's weakened body.

The drug Lazolvan has an internationally patented name Ambroxol.The active substance of the drug - ambroxol, significantly increases the resistance of the respiratory system to infections that have penetrated the body. Also, ambroxol causes the production of surfactant - a substance washing the bronchi and lungs from the inside, by this action cleaning the mucous tissues.

After the penetration of the falcon in the bronchi, the cilia of the epithelium begin to move forward towards the exit from the bronchial tree, thus promoting the excretion of sputum. 2 ml of the mortar solution for inhalation contains 15 mg of ambroxol. As auxiliary substances in the manufacturing process of this pharmacological product, other components are also used. In parallel with carrying out inhalations, patients may be prescribed Lazolvan cough syrup. A syrup is a seemingly transparent, thick liquid, colorless or almost colorless. In the instructions for Lazolvan cough syrup, the mucolytic properties of the drug are described, with a pronounced expectorant effect.

Application features

The instructions for the use of Lazolvan for inhalations indicate that the recommended frequency of adult therapy and children aged after six years make daily 1-2 sessions, with a calculation of 2-3 ml of the drug per procedure. Following the instructions of the children's Lazolvan for inhalations, small patients in the treatment of cough should be treated once or twice a day, using no more than 2 ml of solution.

Experts say that absorption is the absorption of the active substances of the drug by the body, extremely high, that's why in the near future you can see positive changes in well-being patient.The maximum effect of lazolvan inhalations for children and adults is achieved already after 3 hours from the moment of penetration of the medicine into the bronchi. The medicine quickly spreads through the respiratory tract, its greatest concentration occurs in the lungs, and therefore there is a pronounced therapeutic effect after such procedures. The time of removal of the active substance from the blood plasma is from 7 to 12 hours. The drug is excreted from the body through the kidneys.

Doctors say that Lazolvan is effective in such diseases of the respiratory tract as:

• all forms of bronchitis;
• obstructive pulmonary disease;
• pneumonia;
• bronchial asthma.

How to carry out the procedure correctly

Do not use Lazolvan solution for coughing for inhalation in its pure form: it must be diluted half with physiological saline. To avoid irritation of the respiratory tract, it is preliminary necessary to slightly preheat the medicine intended for the therapeutic procedure.

To conduct inhalations, as a rule, use a special apparatus - a nebulizer. It can be ultrasonic, compression or mixed type. The most modern version of such a device is a device called a mesh-nebulizer. The procedure is carried out using a mask.

When dry cough lazolvan for inhalation is recommended to use, discovering the first signs of the disease. The procedure allows dry cough from unproductive to translate into productive.

Side effects and contraindications

Before you start taking Lazolvan, you should read the absolute contraindications:

• hypersensitivity;
• the first trimester of pregnancy;
• the period of breastfeeding;
• renal or hepatic insufficiency.

The drug is well tolerated by all patients - both children and adults. In people prone to allergic manifestations, there may be side effects in the form of skin rashes, hives, angioedema, allergic contact dermatitis. There are very rare cases when patients experienced an extremely serious condition - anaphylactic shock. With prolonged use of a solution or drops for Lazolvan inhalations, as well as in cases of an overdose of the patient's preparation, heartburn, gastralgia, nausea and vomiting may be disturbing.

It is not recommended to take Lazolvan concomitantly with other antitussive medications, since such a combination can make it difficult to sputter away from cough. Lazolvan is strictly forbidden to take in the first trimester of pregnancy, in the second and third sometimes it is allowed cough treatment with ambroxol, but only if the possible risk to the mother's health exceeds the risk to the fetus child.

The drug is allowed to be taken as an OTC product. With the proper use of Lazolvan as an antitussive, the process of recovery is accelerated, which reduces the risk of complications.

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Lazolvan (child syrup) medicine: instructions for use

An excellent expectorant, effectively diluting sputum, is the drug "Lazolvan". Children's syrup instructions for use describe how a drug that has a fruity aroma.

In addition to this form, they produce tablets, a solution for inhalation and intravenous injections. Syrup of mute is viscous, with a yellowish tinge or colorless. The medicine can be taken to children at any age, including newborns and premature babies. The syrup is produced in dark vials, in which, in addition to the active ingredient Ambroxol hydrochloride, there are auxiliary substances: menthol, HEC, sorbitol and glycerol, water rectified, flavors (raspberry, orange or apricot), benzoic and tartaric acids, propylene glycol. They release varieties of syrup with 15 or 30 mg of the active ingredient.

Pharmacological properties

The drug "Lazolvan" (children's syrup) describes the use instructions as an effective medicine that promotes the release of pulmonary enzymes that dilute sputum. The agent increases the activity of the cilia of the lungs, promotes rapid excretion and ejection of sputum. The drug increases the reproduction of pulmonary surfactant, which does not allow the disintegration of pulmonary alveoli, accelerates the formation of sputum in dry lungs. The syrup is quickly absorbed and begins to act in half an hour.

Its effect lasts for half a day. The medicine is concentrated in the lung tissue, processing takes place in the liver, and is excreted in the urine.

Indications for use

Means "Lazolvan" (children's syrup) instruction for use recommends taking infectious inflammatory pathologies. It is used for bronchitis and pneumonia, obstructive chronic ailments of the lungs (COPD, bronchopulmonary dysplasia, asthma), which are accompanied by sputum discharge and a violation of its viscosity.

Medication "Lazolvan" (children's syrup): instructions for use

The drug is prescribed to children up to two years for half a teaspoon twice a day. Babies under 6 years old receive the same amount of money three times. Children under 12 years are recommended to take 1 hour. spoon three times a day, after 12 used for 2 hours. spoons.

Medication should be consumed along with cough suppressants. Syrup improves penetration into the lungs and the effectiveness of antibiotics.

Children's syrup "Lazolvan reviews, contraindications and side effects

It is forbidden to give medicine to children with allergies to citrus and atopic diathesis. Parents' comments indicate that the medicine is well tolerated by the kids, and negative reactions are observed in rare cases. Children's cough syrup "Lazolvan" in children with heightened sensitivity can cause vomiting, heartburn, nausea, allergic reactions. Overdose cases are not known. During the treatment, single cases of severe anaphylactic-type reactions were recorded, but their relationship with the use of syrup was not established.

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