Eye drops Nepafenac (Nefepak): instructions for use

Nepafenacum (Nepafenacum) is a drug used in ophthalmology for pain relief, swelling, as well as as an anti-inflammatory agent (fights inflammatory pathogens processes). This drug has a property important in the treatment of cataracts: it does not affect the level of intraocular pressure. Drops are both medicinal and preventive.

Description of the preparation

The active substance of the drug is napafenac, which looks like a yellowish crystalline powder.Eye drops Nepafenac is a sterile suspension of light yellow or light orange color.
One milliliter of solution contains:

• The main substance (napafenac) is 1 mg.
• Excipients: sodium chloride, benzalkonium chloride, tyloxapol, carbomer 974P, mannitol, hydrochloric acid, disodium edetate, water.

Eye drops Nepafenac are produced in polyethylene bottles of medium density of 5 ml, which have a built-in dropper. The vials are placed in cardboard boxes with a detailed instruction on the use of the drug.

Rules for the storage of eye drops Nepafenac:

• The drug should be stored at a temperature of 2 ° C to 30 ° C.
• It is important to place the medicine package in a place inaccessible to children.
• The period of storage of eye drops Nepafenac is two years.
• After opening the bottle, it is allowed to use the drug for no longer than four weeks.
• Do not apply to treat drops after the expiry date printed on the package.

Rules for the use of the drug:

• The medicine is instilled (one drop) with a conjunctivitis bag three times a day;
• Before using drops, the vial of the medicine must be shaken;
• The drug is not intended for injection.A solution of napafenac involves only local application;
• After the procedure, it is important to close the lid of the vial-dropper tightly;
• In the process of "instillation" it is necessary to ensure that the eyedropper does not touch the eye. This will avoid contamination of the vulnerable eye by an available infection;
• After using drops, avoid exposure to the open sun;
• During the treatment with drops of Nepafenac, contact lenses should be avoided;
• Nepaphenac is not applied simultaneously with other eye drops.If it is necessary to use several types of drops, it is important to observe a time interval between instillations of at least 5 minutes.

The use of nepafenac can cause temporary visual impairment.

Visual disorders should be the reason for refusing to drive vehicles.

Drops for the eyes Nepafenac produces the company Alcon Laboratories (Belgium).

Pharmacological action and group

Eye drops Nepafenac belong to the pharmacological group: ophthalmic agents, acetic acid derivatives and related compounds. The drug has analgesic and anti-inflammatory effect, practically does not affect the intraocular pressure.

The active substance contained in the drops is not an active dosage form. After penetrating the eyeball tissue, nepafenac is converted into amfenac, which has a high affinity for the serum albumin of human blood.Amphenac is an active form that inhibits cyclooxygenase (an enzyme that relieves the symptoms of pain and inflammation) and prevents excessive synthesis of prostaglandins (physiologically active substances that increase the sensitivity of a number of receptors to mediators of pain).

The result of the action of amfenac is the reduction of the pain reaction and the reduction of signs of inflammation in the region of the affected eye.

Indications and contraindications in use

Drops for eyes Nepafenac are appointed by an ophthalmologist under the following problem states:

• Pain and inflammation that occurs after surgery to remove cataracts;
• The drug is prescribed for both treatment and for prophylactic purposes;
• The risk of developing macular edema in patients with diabetes after surgery(removal of cataracts);
• The drug is not prescribed in the case of a number of pathological conditions:
• Individual intolerance to all components of the drug for all types of non-steroidal anti-inflammatory drugs;
• Diagnosed bronchial asthma;
• Past cases of acute rhinitis or urticaria after the use of non-steroidal anti-inflammatory drugs.

The doctor appoints Nepafenac with certain precautions to patients who have problems in the system of hemostasis and people receiving drugs that prolong the time of blood clotting.

.

What to do if there are red spots under the eyes and scaly

Inflammation of the upper eyelid - modern approaches to treatment are presented in this article.

Treatment of adenoviral conjunctivitis http://eyesdocs.ru/zabolevaniya/konyunktivit/adenovirusniy.html

.

In pregnancy

Laboratory studies conducted on animals have revealed the possibility of toxic action of the substance on the maternal organism. Also, the drug is presumably capable of inducing premature closure of the botulinum duct. Therefore, taking nepafenac during pregnancy is not recommended.His appointment is possible only in those cases when the potential need for the use of the drug for the mother is higher than the risk of development of undesirable consequences for the child.

It is also necessary to be cautious in prescribing the drug during lactation.

To small children

It is unacceptable to use drops for the eyes of Nepafenac for the treatment of children under the age of ten.

Possible complications caused by the drug

In the case of the use of drops for the eyes of Nepafenac, a number of undesirable or painful effects may occur:

• Headache, dizziness, nausea, vomiting;
• Pain or discomfort in the eye area;
• Corneal opacity;
• Sensation of dryness or itching, sensation of foreign body in the eye area;
• Crusts on the eyelids;
• Lachrymation;
• Keratitis;
• Irit;
• Choroidal effusion;
• Defects of the epithelium;
• Conjunctival hyperemia;
• Dermatolachalysis;
• Sinusitis;
• Increased blood pressure;
• Decreased visual acuity in the future.

.

Eye drops Methyl ethylpyridinol

Treatment for meibomite of the lower eyelid is described in this article.

What is macular degeneration of the retina http://eyesdocs.ru/zabolevaniya/makulodistrofiya/setchatki-glaza-lechenie-s-pomoshhyu-narodnyx-sredstv.html

.

Some kinds of undesirable sensations and painful manifestations can be the natural consequences of surgical intervention. In some patients, bleeding time may increase due to the effect of the drug on platelet aggregation. Nepafenac can also cause a delay in wound healing.

The risk of development of such consequences of the use of drops is high in patients with diabetes mellitus.

Eye drops on the basis of the active substance napafenac is not recommended for use in parallel with prostaglandin analogues.

Overdosage was not observed either in the case of topical application, or with accidental ingestion.

Video

conclusions

Nepaphenac eye drops are used to treat pain and prevent the development of inflammation after a cataract surgery. The drug "struggles" with microorganisms that provoke inflammatory processes in the affected area of ​​the eye, reduces the edema that develops after the operation, acts as an analgesic.

However, a significant drawback of Nepafenac is the huge number of different side effects.
An important condition for the use of the drug is a thorough examination of the patient before the appointment. The attending physician should regularly monitor the patient and follow all the features of the recovery process after the operation.