Traicor

Trakor is a lipid-lowering drug that is used for dyslipidemia, and is also used in diabetes mellitus if diet therapy and physical exercise are ineffective.

It is manufactured in France, where the drug is sold in the form of tablets. The action of the drug is due to the main component, which is fenofibrate. The drug lowers the level of fibrinogen and the content of atherogenic cholesterol fractions in the blood (VLDL LDL), enhancing the excretion of uric acid.

In the field of modern medicine, Traykor is widely used to combat hyperlipidemia and hypercholesterolemia. The drug gives a good effect in the treatment of patients suffering from diabetes, if diet therapy and other therapeutic techniques have not produced the proper result.

Clinical and pharmacological group

A hypolipidemic agent from the group of fibroic acid derivatives.

Terms of sale from pharmacies

Can buyby prescription.

Price

How much does Trakor cost in pharmacies? The average price is at the level of900 rubles.

Composition and form of release

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Trakor is available in the form of oblong tablets, which are covered with a thin film shell of light white color. The tablets are labeled with inscriptions. On one side number 145 is indicated, on the second side is the logo "FOURNIER".

Tablets are given in a dosage of 145 mg. In the package can be from 10 to 300 pieces. There is also a form of release with a dosage of 160 mg of the active substance. In one package can contain from 10 to 100 pieces. In one cardboard box, in which the drug is released, there are 3 blisters with tablets and instructions.

In the composition of the drug the main active substance ismicronized fenofibrate.

pharmachologic effect

The drug contains fenofibrate. This substance belongs to the group of fibrates, it has hypolipidemic action. The agent activates PPAR-alpha, thereby enhancing lipolysis, stimulating the synthesis of apoproteins of types AI, AII, inhibiting the production of apo-protein CIII.

The substance causes a decrease in the plasma concentration of atherogenic lipoproteins by enhancing their excretion. When the drug is treated with a decrease in the levels of total cholesterol, triglycerides, a reduction in extravascular deposits of cholesterol. Fenofibrate lowers the level of fibrinogen, C-reactive protein, prevents platelet aggregation associated with epinephrine, arachidonic acid and adenosine diphosphate. In addition, the drug has a uricosuric effect.

Indications for use

Find out what helps this tool, you can by studying the instructions and indications for its purpose.

Apply it recommended for violations such as:

hypercholesterolemia;
hypertriglyceridemia;
hyperlipoproteinemia.

With such diseases, Trakor is used if non-drug methods of treatment do not bring results. Also, a doctor can prescribe this drug to overcome other diseases as part of complex therapy, if such actions are appropriate.

Contraindications

Absolute:

severe renal failure (with creatinine clearance <20ml / min);
severe hepatic insufficiency, including cirrhosis of the liver;
diseases of the gallbladder;
lactation period;
age to 18 years;
individual intolerance to the components of the drug;
Congenital fructoemia, insufficiency of sugarase / isomaltase (for tablets of 145 mg);
Congenital insufficiency of lactase, galactosemia, impaired absorption of glucose and galactose;
a history of allergic reactions to peanuts, soy lecithin, peanut oil or related products;
weighed anamnesis on photosensitivity / phototoxicity during therapy with ketoprofen or fibrates.

Relative (diseases / conditions, in the presence of which the appointment of Tracor requires caution):

hypothyroidism;
elderly age;
pregnancy;
renal or hepatic insufficiency;
a history of hereditary muscle diseases;
excessive use of alcohol;
Combined therapy with oral anticoagulants, inhibitors of HMG-CoA reductase

Intended use for pregnancy and lactation

The experience of using Tracor in pregnant women is very limited. During the experimental studies in laboratory pregnant female rats there was no embryotoxic or teratogenic effect for the fetus. Despite this information, you can use Trakor tablets to treat future mothers only if the expected benefit for the mother exceeds possible risks to the fetus.

During breastfeeding the drug is not prescribed to nursing mothers, as active substances of tablets can be excreted with milk and enter the baby. If necessary, the drug should decide whether to stop lactation.

Dosage and route of administration

As indicated in the instructions for use, the medication is taken orally, with a glass of water, without chewing, wholly. Tablets Trakor 145 mg can be taken regardless of food intake at any time of the day, 160 mg - preferably with meals.

Traykor is prescribed for 1 tablet a day.

Transition without dose adjustment is possible:

1 capsule Lipantil 200 M or 1 tablet of Tracor 160 mg: for 1 tablet of Tracor 145 mg;
1 capsule Lipantil 200 M: 1 tablet of Tracor 160 mg.

Older patients do not need a dose adjustment.

With renal failure, the drug is prescribed in a reduced dose.

Therapy should be carried out for a long time with the simultaneous observance of the diet.

Side effects

When using Tracor, side effects may occur. If their intensity is significant, they must refuse treatment with this drug.

The main side effects of the drug are:

myositis;
urticaria;
pancreatitis;
itching;
nausea;
headache;
muscle spasms;
increase in the number of leukocytes;
increased gassing;
diarrhea;
abdominal pain;
skin rashes;
the formation of gallstones;
alopecia;
decreased sexual activity.

If necessary, they should be removed by a doctor. Specific antidote does not exist, so patients are offered symptomatic therapy.

Overdose

Episodes of an overdose by Tracor are not described at this time. Antidote to the drug is unknown. In case of suspicion of a possible overdose, treatment should be prescribed corresponding to the reported negative symptoms. Conducting hemodialysis will not be effective.

special instructions

Prior to the appointment of Tracor, appropriate treatment is required to eliminate the cause of secondary hypercholesterolemia. In particular, it refers to such diseases / conditions as dysproteinemia, uncontrolled type 2 diabetes mellitus, nephrotic syndrome, hypothyroidism, obstructive liver disease, alcoholism, the consequences of drug therapy.

The attending physician should periodically evaluate the effectiveness of the therapy. The criterion for this assessment is the serum lipid content (including total cholesterol, triglycerides and LDL). In the absence of the effect of treatment after a few months (usually after 3 months) of taking Tracor tablets, the question of the desirability of its further application and the possibility of alternative therapy should be reconsidered.

There is information about the occurrence of pancreatitis. Possible reasons for its development are the lack of efficiency of Tracor in severe hypertriglyceridemia, the direct effect of the drug, and secondary phenomena that are associated with the formation of sediment or the presence of stones in the gallbladder against the background of obstruction of the common bile duct.

There are cases of toxic effects of Tracor on muscle tissue, including very rare cases of rhabdomyolysis. The frequency of this disorder increases with a history of hypoalbuminemia and renal insufficiency. The possibility of complications increases in cases of renal failure and hypoalbuminemia.

If the increase in creatinine concentration is more than 50% of the upper limit of the norm, the therapy is suspended. In the first 3 months of use, it is recommended to determine the concentration of creatinine.

Interaction with other drugs

When used simultaneously with cyclosporine, kidney function may worsen and the concentration of cyclosporine in the blood plasma increase.

With the simultaneous use of hypoglycemic agents with derivatives of sulfonylureas, there are reports of increased hypoglycemic effects.

With the simultaneous use of indirect anticoagulants (including acenocoumarol, warfarin), their effects are intensified. It is believed that fibrates increase the affinity of anticoagulants to the corresponding receptors or, possibly, disrupt their metabolism.

Traikor - reviews

Reviews about Traykor 145 mg and 160 mg are few and ambiguous.

Some doctors will successfully apply it to normalize the lipid profile of their patients, observe high efficiency of this drug and are completely satisfied with the results of therapy with its use. Other specialists refer to the action of Tracor with caution and note that possible side effects drug (formation of stones, rhabdomyolysis, photosensitivity) prevail over its potential effects.

In any case, the appointment of medicinal remedies similar to Tracor remains at the doctor's discretion and in the absence of contraindications to their use or risk factors for the negative consequences of such treatment is likely to lead to the expected positive result.

Analogues

Structural analogs for the active substance:

Grofibrate;
Lipantil 200 M;
Fenofibrate;
Excl.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

Trakor must be stored in the manufacturer's packaging. The permissible storage temperature is 25 degrees.

The shelf life of the drug depends on the concentration of the active substance in the preparation. When the tablets are purchased at a dosage of 145 mg, their shelf life may reach 3 years. When using tablets at a dosage of 160 mg, the shelf life is reduced by one year and is 2 years.