Diabetes MTB (60 mg): instructions for use

Diabetes MB is a drug designed to treat type 2 diabetes.

The active substance of the drug is gliclazide, stimulating beta cells of the pancreas in order that they produce more insulin, this causes a decrease in blood sugar. MB designation of modified release tablets. Gliklazid is a sulfonylurea derivative. Of the tablets, gliclazide is released within 24 hours in uniform proportions, which is a plus in the treatment of diabetes.

On this page you will find all information about Diabetes MV: the full instructions for use for this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Diabetes MV. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Oral hypoglycemic drug.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Diabetes MW cost? The average price in pharmacies is at the level of350 rubles.

Form of issue and composition

"Diabeton" is produced in the following forms:

• Tablets 80 mg.
• Modified-release tablets Diabetes MW 60 mg.

The active substance of the drug is gliclazide - 80 mg (60 mg). The composition includes auxiliary substances: maltodextrin, magnesium stearate, hypromellose 100 cP, lactose monohydrate, colloidal silicon dioxide anhydrous.

Pharmacological effect

The active component of Diabeton (gliclazide) exerts a pronounced hypoglycemic effect, effectively reducing the concentration of glucose in the blood and stimulating the secretion of insulin by the β cells of the islets of Langerhans.

Diabetes on the background of type 2 diabetes mellitus in response to the intake of glucose contributes to the restoration of the early peak of insulin secretion and simultaneously enhances the second phase of its secretion. In addition, Diabeton, according to instructions, reduces the risk of developing thrombosis of small vessels, affecting the mechanisms that are the main factors in the development of complications of diabetes.

Indications for use

According to the instruction, Diabeton is appointed:

1. In the treatment of type 2 diabetes mellitus on the background of insufficient effectiveness from physical exertion and diet therapy;
2. To prevent complications of diabetes mellitus - reduce the risk of stroke, retinopathy, nephropathy and myocardial infarction.

Contraindications

This medication can only be used as directed by the doctor after a thorough examination and determination of the type of diabetes mellitus. Diabetes MV tablets have the following limitations and contraindications:

1. Type 1 diabetes mellitus;
2. Age is less than 18 years;
3. Ketoacidosis against diabetes mellitus;
4. Lactase insufficiency or galactosemia;
5. The period of pregnancy and breastfeeding;
6. Severe renal or hepatic insufficiency;
7. Individual intolerance to the components of the drug;
8. Diabetic coma in the patient - the introduction of this drug can only aggravate the patient's condition.

With particular caution, the drug Diabetes MV is prescribed to patients with a deviation in the work of the heart, hypothyroidism, chronic alcoholism, against the background of glucocorticosteroid therapy, elderly patients.

Application in pregnancy and lactation

Diabetes MW at any dose during pregnancy is prohibited, as are other oral medications for diabetes. Instead, they prescribe insulin preparations. It is advisable to switch to insulin in the planning period. If the pregnancy occurred during the admission of Diabetes, the pill should be urgently canceled.

Studies of the penetration of glyclazide into breast milk and through it into the body of the child was not carried out, therefore, during the period of breastfeeding, Diabeton is not prescribed.

Instructions for use

The instructions for use indicate that Diabetes MB is intended only for the treatment of adults. The recommended dose of the drug should be taken orally, 1 time / day, preferably during breakfast.

• The daily dose is 30-120 mg (1 / 2-2 tab.) In 1 dose. It is recommended to swallow a pill or half of the whole tablet without chewing or grinding.

If you skip one or more doses of the drug, you can not take a higher dose to the next dose, the missed dose should be taken the next day. As with other hypoglycemic drugs, the dose of the drug in each case must be selected individually, depending on the concentration of blood glucose and HbA1c.

• The initial recommended dose for adults (including for elderly patients ≥65 years) is 30 mg (1/2 table) / day.

In case of adequate control, the drug in this dose can be used for maintenance therapy. With inadequate glycemic control, the daily dose of the drug can be sequentially increased to 60 mg, 90 mg or 120 mg. Increase in the dose is possible not earlier than after 1 month of therapy with the drug at a previously prescribed dose. Exception is made by patients, in whom the blood glucose concentration did not decrease after 2 weeks of therapy. In such cases, the dose of the drug may be increased 2 weeks after the start of the treatment.

• The maximum recommended daily dose of the drug is 120 mg.

One tablet of the drug Diabetes MB tablets with a modified release of 60 mg is equivalent to 2 tablets. drug Diabetes MB tablets with a modified release of 30 mg. The presence of a notch on the tablets of 60 mg allows you to divide the pill and take the daily dose as 30 mg (1/2 table. 60 mg), and if necessary 90 mg (1 tab. 60 mg and 1/2 tab. 60 mg).

Side effects

The most dangerous side effect is reduced blood sugar, hypoglycemia. Her symptoms are: headache, fatigue, irritability, nightmares, palpitations. In severe cases, the patient may lose consciousness.

Diabetone CF causes severe hypoglycemia less often than other drugs - sulfonylureas. Other side effects - abdominal pain, nausea, vomiting, diarrhea, constipation, rash, skin itches, increased activity of liver enzymes (AST, ALT, APF). At the beginning of Diabeton's admission, there may be temporary visual impairment - due to the fact that sugar is quickly reduced in the blood. Hepatitis and jaundice are also possible, but rarely.

Unfavorable changes in the composition of the blood are extremely rare.

Overdose

When an overdose of sulfonylurea derivatives may develop hypoglycemia. Sugar in the blood will fall below the norm, and this is dangerous. Light hypoglycemia can be stopped on its own, and in severe cases, urgent medical attention is required.

special instructions

After a long period of treatment, the effectiveness of Diabetes MW can be reduced. This may be due to the progression of the disease or a decrease in the therapeutic response to the drug - secondary drug resistance. Before diagnosing this disorder, it is necessary to assess the adequacy of dose selection and patient compliance with the prescribed diet.

During the therapy, hypoglycemia may develop, and in some cases, prolonged / severe form, which requires hospitalization and intravenous dextrose administration for several days. To avoid the development of hypoglycemia requires a thorough individual selection of drugs and dosage regimen.

The likelihood of developing hypoglycemia increases in the following cases:

• kidney failure;
• severe hepatic impairment;
• Diabetes MV overdose;
• combined use with certain medicines;
• an imbalance between the amount of carbohydrates taken and physical activity;
• missing meals, irregular / inadequate nutrition, changing diets and fasting;
• refusal / inability of the patient to control his condition and follow the prescriptions of the doctor (in particular, this applies to elderly patients);
• Some endocrine disorders (thyroid disease, adrenal and pituitary insufficiency).

Weakening of glycemic control during the intake of Diabetes MF is possible with fever, trauma, infectious diseases or large surgical interventions. In these cases, it may be necessary to cancel the drug and prescribe insulin therapy.

Drug Interactions

Many drugs increase the risk of hypoglycemia if taken with Diabetes. This should be taken into account by the doctor, prescribing the combined treatment of diabetes with acarbose, metformin, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, GLP-1 agonists, and insulin.

The effect of Diabetone MB increases drugs from hypertension - beta-blockers and ACE inhibitors, as well as fluconazole, histamine H2 blockers, MAO inhibitors, sulfonamides, clarithromycin. Other drugs can weaken the action of Gliclazide. Read the official instructions for use.

Tell your doctor about all medicines, dietary supplements and herbs that you take before you are prescribed a pill from diabetes. Understand how to control sugar in the blood. Know what to do if it rises or falls too low.

Reviews

We picked up some of the people's opinions about the drug Diabetes MV:

1. Sasha. Diabetes was discovered by chance, blood tests were performed, and there was glucose on an empty stomach - 13, and there were no special symptoms, I lived as usual. I immediately wanted insulin, I refused. Began to drink Siofor and Diabeton. Sugar in the first days fell to 9, and then very slowly, a whole month crawled down. Now 6, maximum 8.
2. Valentine. Today I got 60. Recommendation on recipe 1/2 twice a day. I read prem 1 time in the morning. What to do? Constantly different doctors and each one is oppressed. It is difficult to enter one. Previous Gliadab Mw with metmorphine 850 (2-time-metmorphine) reduced the SC to 3.75. After 2 hours less than 5. Here and replaced. Why not reduce the dose of metformin? I was already living peacefully.
3. Lera. The year Metlformin drank, dropped 15 kg during this time, another 10 extra left. The doctor transferred me to Diabetes in a minimum dose of 30 mg. At first I was even glad, I drink only 1 time and sugar reduces well. And then I realized that every skipping meal or a small portion leads to a drop in sugar. As a result, my weight loss stopped, and already 2 kg scored. At my own peril and risk, I returned to Metformin, I will build further.

According to reviews, Diabeton MB is an effective drug that helps reduce sugar levels. The development of side effects is reported only in rare cases. Of the deficiencies usually indicate a sufficiently high cost of the drug.

Analogues

Analogues of the drug Diabetes MW are the following:

• Glioadab tablets;
• Glidiab MB;
• Diabetes FM;
• Gliklazid MB.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Keep the drug in a dry, dark, cool place, away from children. The shelf life is indicated on the package, it is recommended to discard the drug at its expiration.

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