Fibrinogen is elevated in pregnancy - is it worth to be afraid and why?

Each pregnant woman during the period of bearing a baby gives a sufficiently large number of tests that help the doctor in assessing both the health of the future mother and the condition of the fetus.

One important indicator is the serum fibrinogen level. This analysis is carried out only three times during the entire period of pregnancy. With available deviations, the doctor may prescribe additional studies.


  • 1 What is
  • 2 Pregnancy rate in the first, second and third trimester
  • 3 Increase in the normal level and its causes
  • 4 Danger and effect on the cardiovascular system
  • 5 Tactics of treatment: how to reduce the content of

What is this

Fibrinogen - protein,which produces the liver .It is a precursor to the synthesis of fibrin, a substance that forms a clot when blood coagulates.

The importance of this indicator is that, with deviations from the normal level, there can be both fetal growth retardation and problems in the maternal body.

In the process of childbirth, there is a lot of blood loss, and this important protein helps to avoid profuse bleeding .That's why a woman is prescribed a coagulogram and, if necessary, a hemostasiogram, with which other parameters of the serum are determined.

Pregnancy rate in the first, second and third trimester

Normal levels in expectant mothers differ from those of women who do not bear a child, and also vary depending on the term.

If in nonpregnant patients is an average of 3 g / l of , then in future mothers, the fibrinogen levels for pregnancy in trimester are as follows:

  • 1 trimester - 2.98 g / l;
  • 2nd trimester - 3.1 g / l;
  • 3 trimester - 6 g / l.

Usually, the analysis is taken from the vein. Do not forget that this procedure is always performed on an empty stomach , and it is also recommended to exclude physical activity, to avoid stressful situations.

The first time a coagulogram is performed immediately after the future mother is registered, the second time at 22 weeks, the third - 34-36 weeks. Sometimes a doctor prescribes conducting such an analysis before the birth.

Increase in the normal level and its causes

Exceeding the rate of fibrinogen during pregnancy shows that the in a woman has thick blood .The danger of this phenomenon is that blood vessels can form clots. This applies to the vascular system of the placenta, which can lead to inadequate nutrition of the fetus and a delay in its development. The child may develop signs of hypoxia.

If fibrinogen is elevated in pregnancy, most likely, is the result of :

  • of inflammatory processes caused by infections;
  • decreased thyroid function;
  • tissue necrosis;
  • development of neoplasms;
  • pneumonia;
  • infarction;

In some cases, the elevated concentration of this indicator of may be an individual feature of the organism, and may also be the result of prolonged intake of estrogen-based hormones before pregnancy.

In some cases, the excess of the value is possible after operations of , which were carried out relatively recently, by burns.

Sometimes an increase can be observed with an incorrect preparation for the study. As already mentioned above, the level of coagulation can be affected by stress and overstrain, fatty foods taken on the eve, an incorrect water regime.

Danger and impact on the cardiovascular system

Despite the various causes of increased fibrinogen in pregnant women, too much blood leads to the same effects, affecting both the health of the woman herself and the prenatal state of the child.

Blood thickening can lead to:

  • development of thrombosis and thrombophlebitis;
  • placental detachment in the early stages, and as a consequence, to miscarriage;
  • of a frozen pregnancy;
  • for premature delivery;
  • to the occurrence of gestosis;
  • obstruction of the umbilical cord and fetal death.
Occurrence of thrombosis is the most severe consequence and can lead to fatal outcome of the mother and fetus.

Tactics of treatment: how to reduce the content of

If a deviation from the norm is detected, the doctor will prescribe additional tests to determine the cause of high fibrinogen levels during pregnancy. Treatment is mandatory. Specialist prescribes both vitamin therapy and serum-mediated medications. In some cases, injections of drugs are carried out in the abdomen.

Also reducing the serum density can help adjust the diet.

For this( in the absence of allergic reactions), it is recommended that future mothers use beetroot, sea kale, grapefruit, pomegranate, broth of cranberries, green tea, grape juice, sunflower seeds, red pepper, tomatoes, cucumbers daily. You can also prepare a decoction of chestnut, infusion of the root of the peony.

If a pregnant woman has serious bleeding disorders, the is referred to a woman under supervision of and delivered to specialized perinatal centers where the expectant mother is prepared for obstetric care and, if necessary, for surgery.

Subject to all prescriptions of specialists, the risk of complications in the mother and child caused by increased blood clotting is significantly reduced.

The level of this protein in the blood in pregnant women is always increased compared to the indices of women who do not bear the child .But if the fibrinogen during pregnancy is significantly higher than normal - this is a dangerous signal that requires timely treatment. Absence of therapy and non-observance by the future mother of all prescriptions of the doctor can lead to a delay in fetal development, miscarriage, and also death of the most pregnant woman.