Goldline and Goldline Plus: user's guide and feedback

Goldline Capsules have the main distinguishing ability - an effective effect on the body and individual processes aimed at weight loss.

It's not for nothing that the drug is prescribed to people who are obese, when diets and restrictions do not bring results. The active component included in the composition works successfully with the correct reception. The specialist in the design develops a scheme of application and dosage, taking into account individual characteristics. Positive feedback allows you to see the effectiveness of the drug in the fight against excess kilograms.

On this page you will find all information about Goldline: full instructions for use on this medication medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Goldline. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

The drug for the treatment of obesity central action.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Goldline cost? The average price of diet pills in Russian pharmacies:

• from 1000 rubles. for capsules 10 mg № 30;
• from 1560 rubles. for capsules 10 mg №60;
• from 1450 rubles. for capsules 15 mg № 30;
• from 2300 rubles. for capsules 15 mg №60;
• from 2950 rubles. for capsules 15 mg №90.

If you want without a prescription, you can order them online. In large cities (for example, in Krasnoyarsk, Moscow or Yekaterinburg) online pharmacies offer to buy Goldline with home delivery.

Form of issue and composition

The drug Goldline is available in the form of capsules for oral administration (ingestion). They have a solid consistency, white color and blue lid. Inside of them is a white powder.

• The capsule contains the main active substance of the drug - sibutramine hydrochloride monohydrate in a concentration of 10 mg.

It also includes auxiliary components, which include:

1. Titanium dioxide.
2. The quinoline dye is yellow.
3. Gelatin.
4. Sodium lauryl sulfate.
5. Silica.
6. Lactose.
7. Microcrystalline cellulose.
8. Magnesium stearate.
9. Dye sunset sunset yellow.
10. The dye fuchsin is acidic (D & amp; 33) and the dye is a brilliant blue in the capsule capsule.

Goldline capsules are packaged in a blister for 10 pieces. Cardboard pack contains 3 blisters with capsules (30 capsules) and instruction on the use of the drug.

Pharmacological effect

Goldline Plus action is due to the components included in it. Sibutramine is a prodrug that in the body turns into metabolites - primary and secondary amines, which both realize therapeutic action - block the re-acquisition of neurotransmitters - serotonin, norepinephrine, dopamine - in synaptic slits. Due to this, the sense of satiety is prolonged, the feeling of hunger decreases and the heat production is increased.

Clinical studies have shown that reducing hunger and prolonging the feeling of satiety leads to a decrease in the amount of food consumed by 20%, caloric intake by 25%. Due to the increase in heat production, an additional 100 kcal is burned per day. Against the background of taking Goldline Plus, in addition to weight loss, there is a rise in blood levels of lipoproteins density (HDL), lowering of low-density lipoproteins (LDL), total cholesterol, triglycerides and urinary acid.

Microcrystalline cellulose (MCC) is an enterosorbent, possesses nonspecific detoxification and sorbent effects, binds and removes from the body various microorganisms, the products of their vital activity, allergens, xenobiotics, toxins of endogenous and exogenous nature.

Indications for use

According to the instructions, Goldline is used for alimentary obesity with a body mass index of about 30 kg per 1 m2 or 27 kg per 1 m2, which is combined with dyslipoproteinemia or diabetes mellitus of the second type.

Contraindications

The drug is not prescribed for children under 18 years of age and for patients over 65 years of age. The use of Goldline is contraindicated in case of hypersensitivity to the components that make up its composition, and also in the following cases:

1. Severe dysfunction of the liver or kidney;
2. Cerebrovascular diseases;
3. Pheochromocytoma;
4. Arrhythmias;
5. Mental diseases;
6. The use of other drugs that have an effect on the central nervous system;
7. Ischemic heart disease;
8. Established alcohol, drug or pharmacological dependence;
9. Benign prostatic hyperplasia;
10. Congenital heart disease;
11. Closed-angle glaucoma;
12. Pregnancy and during the period of breastfeeding;
13. Syndrome Gilles de la Tourette;
14. Presence of organic causes of obesity;
15. Simultaneous administration of MAO inhibitors or their use within 14 days prior to the appointment of Goldline;
16. The use of other drugs of central action to reduce body weight;
17. Uncontrolled hypertension;
18. Serious eating disorders.

With caution Goldline is prescribed to patients with arterial hypertension, chronic insufficiency blood circulation, arrhythmia, motor and verbal tics in anamnesis, coronary artery disease and cholelithiasis.

Application in pregnancy and lactation

Since to date there is not a sufficiently convincing number of studies in safety of sibutramine on the fetus, this drug should not be used when pregnancy.

Do not take Goldline during breastfeeding.

Women of childbearing age should take contraceptives while taking Goldline.

Instructions for use

The instructions for use indicate that Goldline is prescribed by mouth 1 time / day. The dose is set individually, depending on the tolerability and clinical effectiveness.

• An initial dose of 10 mg is recommended, with a poor tolerance of 5 mg.

Capsules should be taken in the morning without chewing and drinking with a sufficient amount of liquid (a glass of water). The drug can be taken as an empty stomach or combined with a meal. If within 4 weeks from the beginning of treatment there is no reduction in body weight by 5% or more, the dose increases to 15 mg / day.

Treatment by Goldline should not last more than 3 months in patients who do not respond well enough to therapy, i.e. who during the 3 months of treatment can not achieve a 5% reduction in body weight from the baseline level. Treatment should not be continued if, in further therapy, after the body weight reduction is achieved, the patient again adds 3 kg or more in the body mass. The duration of treatment should not exceed 2 years, since there is no data on efficacy and safety for a longer period of sibutramine intake.

It is also worth remembering that Goldline treatment should be carried out in combination with diet and exercise under the supervision of a doctor who has practical experience in the treatment of obesity.

Side effects

The cardiovascular system can react to the drug with the following undesirable reactions:

• Tachycardia;
• Exacerbation of hemorrhoids;
• Symptoms of vasodilation, including skin flushing;
• Palpitation;
• Increase in blood pressure and heart rate.

From the central nervous system, Goldline sometimes causes the following side effects:

• Insomnia;
• Paresthesia;
• Dizziness;
• Headache;
• Feeling anxious.

On the part of the digestive system, the use of Goldline can cause the following side effects:

• Loss of appetite;
• Change of taste;
• Dry mouth;
• Nausea;
• Constipation.

In some cases, Goldline may cause the following adverse reactions:

• Hemorrhages in the skin;
• Thrombocytopenia;
• Drowsiness;
• Anxiety;
• Nervousness;
• Convulsions;
• Rhinitis;
• Grippopodobny syndrome;
• Paradoxical increase in appetite;
• Dysmenorrhea;
• Abdominal pain;
• Back pain;
• Edema;
• Bleeding;
• Acute interstitial nephritis;
• Itching itch;
• Thirst;
• Emotional lability;
• Irritability;
• Depression;
• Transient increase in hepatic enzyme activity in the blood.

In general, the side effects of taking Goldline are observed during the first month of admission, they are of a non-severe nature, do not require pharmacological correction, and go through the month on their own.

Overdose

In reviews about Goldlayne it is reported that with an overdose of medicament may occur dizziness, headaches, increased blood pressure, tachycardia. Treatment is symptomatic.

special instructions

The application is possible only in those cases when all other measures aimed at lowering the body weight are ineffective. Treatment should be carried out under the supervision of a doctor who has experience in correcting obesity in the framework of complex therapy (diet, changing eating habits and lifestyle, increasing physical activity). The period of admission in a dose of 15 mg should be limited in time.

Drug Interactions

1. Do not combine Goldline with other drugs that increase serotonin levels in the blood.
2. Metabolism of sibutramine can accelerate the antibiotics of the macrolide group, rifampicin, phenytoin, carbamazepine, phenobarbital and dexamethasone.
3. Plasma concentrations of sibutramine metabolites increase with the action of inhibitors of microsomal oxidation, which is accompanied by an increase in heart rate and a clinically insignificant increase in the QT interval.
4. The drug does not affect the effectiveness of oral contraceptives.
5. With simultaneous reception of Goldline with ephedrine, phenylpropanolamine, pseudoephedrine and combined means for treating colds containing these substances, there is a risk of increased blood pressure pressure.
6. When used simultaneously with selective serotonin reuptake inhibitors, some drugs for treatment of migraine, as well as opioid analgesics and antitussives can develop serotonin syndrome.
7. Ethanol does not affect the effectiveness of the drug, but it is not at all combined with the dietary measures recommended for the administration of sibutramine.

Reviews

We picked up some reviews of losing weight (with a photo before and after) about the Goldline drug:

1. Alina. I used to take Goldline, now switched to Goldline PLUS, the composition has changed a little, but the active substance and principle action is the same, the result is, for 2 months dropped 7 kg, although the dry mouth was the first month, but now all excellent!
2. Olga. She drank a month and the doctor canceled because of the deterioration of well-being. He said that you can try again in a month. I can say one thing, after a week of eating, the appetite dropped sharply. I got a small portion of it. I try to restrain the growing feeling of hunger, but I understand that the effect was achieved thanks to the action of sibutramine.
3. Eugene. As I drank goldlite, I had a pobochka-heart beat heartbeat. Has grown thin. But with discomfort. Then she concluded that it could be combined with smoking and coffee. Now she quit smoking. I decided to take the gold line again.) And everything is different, Roma like thirst is all normal. To eat does not want to be absolutely. But I keep the PP, with the necessary portions. Thus I develop a habit. And then I'll throw Gold Line. I'll start to eat and pipets-do not take long ...
4. Miroslava. How many read bad reviews about sibutramine. I did not think that I would decide on his reception. The doctor prescribed and said that before the radical measures this is the only option. I tried and do not repent. I want to spend time with my grandson, and not in hospital queues. After 5 months it became easier by 23 kg. Now you can run and play ball. During the reception, she did not observe any side effects. I recommend!
5. Svetlana. I am satisfied with the results of taking the drug. I bought the medicine through an online pharmacy, without a prescription, at my own risk. I was helped, but there were side effects: sleep disturbance, thirst and dryness was felt. On account of losing weight: weighed 85 kg, threw off 5 kg. This is my first month of admission, I will continue the course. Has got packing for 3 months, the appetite was gone completely. I take vitamins.

Doctors in the reviews of Goldline tablets write thatsibutramineIs a potent substance that can be dispensed in pharmacies solely on prescription. It has a lot of contraindications and often provokes side effects. Thus, to take a drug for weight loss, they recommend only after consulting a specialist and a thorough assessment of the state of health.

Often among the reviews about Goldline there are also reviews about Goldline Light. Unlike Goldline - this is not a medicine, but a dietary supplement. As noted women and girls taking the drug, the effect of its use is noticeable only if a low-calorie diet is observed and a sufficient level of physical activity is provided.

Analogues

Sibutramine is also the main active ingredient in such known drugs as:

• Lindax;
• Meridia;
• Reduxin.

Before using analogues, consult your doctor.

Storage conditions and shelf life

According to the instruction, Goldline is recommended to store in a dark and dry place out of reach of children, at a temperature not exceeding 25 ° C.

The shelf life of the capsules is 2 years.

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