What helps the Ascofen-P tablets? Instructions and references

Ascofen is a combined analgesic antipretics.

Due to the components included in its composition has anti-inflammatory, analgesic and psycho-stimulating effect.

On this page you will find all information about Ascomen-P: full instructions for use with this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Ascofen-P. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

An analgesic-antipyretics of a combined composition.

Conditions of leave from pharmacies

Available without a prescription.

Price list

How much does Ascofen-P cost? The average price in pharmacies is at the level of45 rubles.

Form of issue and composition

Ascofen-P is available in tablets, each containing:

Aspirin (acetylsalicylic acid): acting on prostaglandins - active substances that increase sensitivity receptors, it anesthetizes, lowers the temperature and has an anti-inflammatory effect. The drug prevents thrombosis, "dilutes" the blood. The content of aspirin in 1 tablet of ascophene is 200 mg.
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Caffeine (40 mg in 1 tablet). Strengthens the analgesic effect of the first two drugs; stimulates the respiratory and vasomotor centers of the brain, contributing to the increase of the physical and mental activity of man. Expands the blood vessels, prevents the gluing of platelets in the blood.
Paracetamol. It also has antipyretic and analgesic effects; is particularly effective in combination with acetylsalicylic acid. The quantitative content of ascophene is the same, and the total dosage of the two drugs in the complex does not exceed the dose shown for monotherapy.

Pharmacological effect

Acetylsalicylic acid inhibits the biosynthesis of mediators of pain and inflammation - prostaglandins, thanks to which reduces puffiness and severity of pain syndrome in diseases of inflammatory genesis. This substance is able to slow platelet aggregation, which reduces the risk of thrombosis, but increases the likelihood of bleeding.

Caffeine has psychostimulating and vasodilating properties. This component normalizes the tone of the cerebral vessels, speeds up blood flow, reduces the feeling of physical and mental fatigue and excites the respiratory center. The substance enhances the effect of the remaining ingredients.

Analgesic and antipyretic properties of acetylsalicylic acid enhances phenocetin. The paracetamol present in Ascofen-P indiscriminately blocks the enzyme cyclooxygenase, which reduces the production of prostaglandins. It also directly affects the hypothalamic center of thermoregulation. Its advantage over phenocetin is that methhemoglobin is not formed in the metabolic process.

Indications for use

What helps Ascofen in the form of tablets? The drug is recommended for:

arthralgia;
neuralgia;
pain in rheumatism;
painful menstruation;
headache;
toothache;
myalgia of different etiology;
fever that accompanies influenza and ARVI.

The medical preparation Ascofen-P acts like classical Aspirin, provides a moderate analgesic effect, stabilizes the temperature regime.

Contraindications

The use of Ascophen-II is contraindicated in the following conditions:

Hypoprothrombinemia;
Avitaminosis K;
Hemophilia;
Hypersensitivity to the components of the drug, including - "aspirin" asthma;
Ulcerous lesions of the digestive tract;
Gastrointestinal bleeding;
Hemorrhagic diathesis;
Renal failure;
Deficiency of glucose-6-phosphate dehydrogenase;
Glaucoma;
Sleep disturbances;
Pregnancy and lactation;
Severe arterial hypertension;
Cardiac ischemia;
Children up to 15 years.

Ascofen-P should be used with caution in liver diseases and gout.

Application in pregnancy and lactation

Admission Ascofen during pregnancy, especially in I and III trimesters, is strictly prohibited. In case of emergency, let us take a single dose of Ascofen during pregnancy in the second trimester. According to researchers, the use of the drug in early pregnancy often causes malformations of the fetus, namely, such pathologies as cleft lip or wolf mouth, which is characterized by cleavage of the upper palate.

Use of Ascofen in pregnancy for more than 25 weeks can lead to a weakening of labor. Just as Ascofen adversely affects the child, provoking the closure of the venous duct, which contributes to the development of hyperplasia of the pulmonary arteries and hypertension of blood vessels in the circulatory system.

If it is necessary to use the drug during lactation, breastfeeding should be stopped. Acetylsalicylic acid is excreted in breast milk, which increases the risk of bleeding in the child due to a violation of the function of platelets.

Instructions for use

The instructions for use indicate that take Ascopen-P inside after eating 1-2 tablets 2-3 times / day.

The maximum daily dose is 6 tablets.
The interval between doses of the drug should be at least 4 hours.
To reduce the irritant effect on the gastrointestinal tract, the drug should be taken after meals, washed down with water, milk, alkaline mineral water.

If there is a violation of the kidney or liver function, the break between doses is not less than 6 hours.

The drug should not be taken more than 5 days with an appointment as an anesthetic and more than 3 days as an antipyretic. Other doses and regimens are prescribed by the doctor.

Side effects

The administration of the drug can promote the development of such undesirable side effects: erosive-ulcerative lesions of the gastrointestinal tract, vomiting, tachycardia, increased blood pressure, bronchospasm, allergic manifestations.

Prolonged taking of tablets can provoke the development of dizziness, headache, blurred vision, tinnitus, bleeding gums, nosebleeds.

Overdose

Overdosing with Ascophen-P is manifested by pain in the stomach, hearing / vision impairment and digestive disorders. If the dosage of this drug has been exceeded significantly, a coma is possible.

In case of poisoning of the body with this drug, it is necessary to immediately wash the stomach and conduct symptomatic therapy.

special instructions

Aspirin has a teratogenic effect, when applied in the first trimester, it results in the cleavage of the upper the third, to the closure of the arterial duct in the fetus and the inhibition of labor. Acetylsalicylic acid is excreted in breast milk and disrupts platelet function, thereby increasing the risk the occurrence of bleeding in a child, and therefore Askofen-P is forbidden to take during breastfeeding.

The drug enhances the effect of steroid hormones, indirect anticoagulants, heparin, reserpine, hypoglycemic drugs, reduces effectiveness antihypertensive medications, furosemide, spironolactone and antidotal agents that promote the excretion of uric acid.
With prolonged use of Ascophen-II, it is necessary to monitor the peripheral blood picture and the functional state of the liver.
With the simultaneous use of Ascophene-P with ethanol, the risk of developing gastrointestinal bleeding and hepatotoxic effects, therefore during the period of treatment should refrain from drinking alcohol-containing beverages.
If the patient who receives Ascofen-P is undergoing surgery, he must warn the doctor about it, as acetylsalicylic acid slows down the process of blood coagulation.
Children under 15 years are contraindicated in all drugs containing acetylsalicylic acid, since in the case of a viral infection, it can cause the development of Reye's syndrome - a dangerous condition accompanied by prolonged vomiting, metabolic acidosis, hyperpyrexia, acute encephalopathy, an increase in the liver and a violation of its function.

The risk of side effects of Ascophen-P increases with simultaneous use with other anti-inflammatory drugs and methotrexate.

Drug Interactions

Ascofen-P reduces the therapeutic effect of indirect coagulants, reserpine, heparin, hypoglycemic drugs, steroid hormones, spironolactone, furosemide, antihypertensive, anti-arthritis agents that promote the excretion of uric acid.

Ascofen-P increases the toxic effect of SCS, sulfonylurea derivatives, methotrexate, non-narcotic analgesics and non-steroidal anti-inflammatory drugs.

It is not recommended to combine the drug with barbiturates, antiepileptic drugs, zidovudine, rifampicin and alcohol.

Paracetamol is able to enhance the effect of anticoagulants.

Reviews

According to numerous reviews, Ascofen is cheap, but at the same time an effective drug that helps in the fight against pain and temperature. Many indicate that even with prolonged use of the drug, its effectiveness is not reduced, but specify that it must be taken periodically.

Experts who also discuss the drug, note that its anti-inflammatory, analgesic and antipyretic abilities are equivalent. Similarly, doctors at various forums advise not to make premature conclusions about the side effect of the drug.