Amizon tablets: instructions for use

Amizon is an antiviral, antipyretic and anti-inflammatory drug that suppresses influenza A viruses.

It effectively inhibits the activity of influenza viruses and other agents of acute respiratory infections due to direct (inhibitory) effect on the penetration of viruses through cell membranes.

On this page you will find all information about Amyzon: the full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Amizon. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Amizon cost? The average price in pharmacies is at the level of400 rubles.

Form of issue and composition

The tablets covered with a film membrane of yellow or yellow-green color, round, biconcave; presence of minor impregnations is allowed on the surface.

1 tablet contains:

• Enisamia iodide 250 mg
• Excipients: lactose monohydrate (200) - 11 mg, microcrystalline cellulose 101 - 21 mg, povidone K17 - 9 mg, croscarmellose sodium - 6 mg, calcium stearate - 3 mg, Opadry II 85F Clear - 10 mg (polyethylene glycol - 1.5 mg, polysorbate 80 - 0.3 mg, polyvinyl alcohol - 5.2 mg, talc - 3 mg).

In addition, Amizon is produced for children in the form of tablets of 0.125 g, which are prescribed to children aged 6 to 12 years. There is also a preparation for children in the form of a syrup (Amyzonchik), which is intended for children from 3 years old for the treatment of acute respiratory infections and influenza.

Pharmacological effect

Amizon is a derivative of isonicotinic acid, belongs to the group of non-narcotic analgesics, it has anti-inflammatory, antipyretic, analgesic effect and immunomodulating interferonogenic effect.

1. The antipyretic properties of Amizon are due to the effect on the thermoregulatory centers of the intermediate brain. The analgesic effect of Amizon occurs through the reticular formation of the brainstem.
2. The effect of Amizon as an immunomodulator is manifested by an increase in humoral (an increase in antibody titer and endogenous interferon in blood plasma by 3-4 times), cellular (stimulation functional activity of T-lymphocytes and macrophages) of immunity, as well as in the effect on factors of natural anti-infective resistance (lysozyme level). The drug is an active oral inducer of endogenous interferon.
3. Anti-inflammatory effect is the result of stabilization of cell and lysosomal membranes, inhibition of basophil degranulation, antioxidant action, normalization of the level of prostaglandins, cyclic nucleotides and energy metabolism in the inflammatory focus, as well as weakening of vascular responses.

Amizon has no hemo- and nephrotoxic properties, it does not adversely affect the blood picture, bone marrow hematopoiesis and the mucous membrane of the gastrointestinal tract. The drug does not have a local irritant effect, allergic properties, embryotoxic, mutagenic and teratogenic effects.

Indications for use

Assign the drug "Amizon" (the instruction details the use of the drug) for the treatment, as well as the prevention of such ailments:

• influenza and other viral respiratory diseases;
• measles, chickenpox, rubella, scarlet fever, parotitis infection;
• pneumonia (bacterial and viral origin);
• Infectious mononucleosis;
• angina;
• skin-joint erisipeloid;
• felinosis ("cat scratch").

Drug use is indicated for nonspecific urgent prevention of mumps infection, scarlet fever, hepatitis (type A, E) and mixed infections.

Contraindications

Amizon should not be taken in the following situations:

• in the presence of hypersensitivity to the substances that make up the drug, especially to iodine;
• pregnancy and lactation;
• at lesions of a liver / kidneys of the serious form;
• under the age of 18 years.

Application in pregnancy and lactation

Instructions for use Amizon

The instructions for use indicate that Amizon is taken orally after a meal, without chewing.

The maximum single dose is 1 g, the daily dose is 2 g. If there are no other recommendations, for a medicinal purpose, adults are usually prescribed 0.25-0.5 g (1-2 tablets) 2-4 times a day, up to 2 g per day for 5-7 days; children from 6 to 12 years are prescribed 0.125 g (½ tablets) 2 to 3 times a day for 5-7 days.

For the prevention of influenza and SARS, Amizone is recommended to take in the following dosages:

• adults - 1 tablet a day for 3-5 days, then - 1 tablet 1 time in 2 - 3 days (for 2-3 weeks);
• children from 6 to 12 years - ½ tablet every other day for 3 weeks;
• children from 12 to 16 years - 1 tablet every other day for 2-3 weeks.

When meningoencephalitis - 0.25 g 3 times a day for 10 days. In complex therapy of viral hepatitis - 0.25 g 3 times a day for the first 5 days of the disease.

In complex therapy of pneumonia - 0.25 g 3 times a day for 10-15 days. With pain syndromes apply 0.25-0.5 g 3-4 times a day for 7-14 days.

Side effects

In the given therapeutic dosages, the drug shows good tolerability, does not show nephrotoxic, allergic, embryotoxic, mutagenic, hepatotoxic properties. Individual patients may note the presence of mild edema of the mucous membranes and a feeling of bitterness. Such phenomena do not require special measures or the withdrawal of Amizon.

Overdose

In case of an overdose, the side effects of the drug are increased. In this case, it is recommended to wash the stomach. Additionally, symptomatic therapy is used.

special instructions

Amizon tablets are well tolerated. Before using them, you should always read the instructions. It is important to pay attention to a number of special instructions:

• Pregnant women in the first trimester use of the drug is prohibited. During the second and third trimester, the taking of tablets is possible only for the intended purpose and under the supervision of the doctor.
• Children under the age of 6 years Amizon in the form of tablets does not apply.
• Tablets Amizon strengthen the effect of antibiotics when they are used together.
• For better therapeutic results, Amisone tablets should be used together with vitamin C or multivitamin preparations.
• Receiving tablets Amizon does not affect the concentration of attention and the speed of psychomotor reactions.

In pharmacies, Amizon is dispensed without a prescription. In case of any doubts or questions about the drug, it is advisable to consult a doctor.

When Amizon is taken, the effect of immunomodulating, antibacterial, and antitoxic agents is greatly enhanced. Optimal and expedient, from the therapeutic point of view, is the combination of Amizon with high doses of vitamins, in particular, ascorbic acid.

Justified is a complex therapy, in which Amizon is combined with interferon. In this case, children are recommended to assign an anti-influenza, as well as normal human leukocyte interferon, and to adult patients - human recombinant genetic engineering.

Reviews

Numerous reviews about Amizon are quite contradictory. Many patients consider it a very effective antiviral drug, but some users note uselessness tablets and their lack of positive effect on the body and the state of the immune system after the course of treatment. At the same time, most doctors say that enisamium iodide has both curative and preventive effects.

According to some reviews, the drug helps to prevent infection with the flu and ARVI diseases during the epidemic. In this case, there are references to the side effects of the drug, for example, the appearance of bitterness in the mouth.

Analogues

Different reasons can underlie the need to replace a remedy with another. The question arises: does the drug "Amizon" have analogues? And what? As with any drug, there are analogues for this drug. But remember that a doctor should replace and prescribe medicine. Self-medication does not always lead to the expected effect.

So, the main analogs of the drug "Amizon" are:

• "Enisamium iodide".
• "Flavozid."
• Mangoherpine.
• "Altabor".
• "Engistol".

Before using analogues, consult your doctor.

Storage conditions and shelf life

Store Amizon in a dark place at a temperature not exceeding 25 ° C.

Shelf life is 3 years.

Effective and inexpensive cough syrups for children and adults.

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