Wifeon Candles: user's guide and feedback

Candles Viferon is a powerful immunostimulating agent with a pronounced antiviral effect.

On this page you will find all information about Viferon: full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Viferon suppositories. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Interferon. Immunomodulating drug with antiviral effect.

Conditions of leave from pharmacies

Released without a doctor's prescription.

Price list

How much are Viferon suppositories? Consider the average prices for candles with different doses.

• For 500 000 IU: the price is 500 000 for 10 pieces - 380-400 rubles, you can buy the product in any pharmacy, the recipe from the specialist will not be required.
• For candles 150 000 IU: the cost is 150 000 for 10 pieces - 150 rubles. This is the smallest dosage of the drug, used for children of the youngest age.
• For the preparation 1 000 000 IU: 1 000 000 for 10 pieces - 540 rubles. This is the strongest dosage, used strictly in acute and dangerous processes by older children and adults.

On the average,that for 1 piece 150 - 15 rubles, candles 500 - 40 rubles, candles , 00 - 54 rubles.

Form of issue and composition

If you need to buy Viferon candles, instructions for use are in each carton. Inside the cardboard box there are 10 candles in a special PVC blister pack. They are made in the form of a torpedo, which is easy to inject into the body. Sometimes a suppository may have a non-uniform color.

• Suppositories are issued with a different dosage of the active substance interferon alfa-2b human recombinant. Its quantity in 1 unit of medicine is written on the package.
• The basis of the candles is cocoa butter and confectionery fat, which help them keep the shape, providing the necessary density. The list of excipients is given in the instructions. They enhance the effect of the drug, performing the functions that they are assigned by pharmacists.

Suppositories Viferon are produced with different contents of active substance, while in children, candles 150000ME and 500000ME are used. In adults, candles are used with a dosage of 10, 00 IU and 30, 00 IU. In addition to candles, Viferon is also produced in such forms as gel and ointment.

Pharmacological effect

Viferon is a preparation of human recombinant interferon alfa-2b (which has an antiviral, immunomodulating and antiproliferative effect. Under the influence of interferon, the activity of natural killers, T-helpers, cytotoxic T-lymphocytes, phagocytic activity, intensity of differentiation of B-lymphocytes, expression of MHC antigens of type I and II.

The drug also directly inhibits the replication and transcription of viruses, chlamydia. Damage to cell membranes, observed during the development of the infectious process, is the reason for reducing the antiviral activity of interferon. Tocopherol acetate and ascorbic acid, which are part of the drug Viferon, are membrane-stabilizing components, antioxidants, in combination with which the antiviral activity of recombinant interferon alpha-2b increases by 10-14 times. In addition, the immunomodulatory effect of interferon on T and B lymphocytes is increased, the content of immunoglobulin E is normalized, there are no side effects effects (fever, fever, influenza-like phenomena) that occur with the parenteral administration of interferon preparations.

It was found that when Viferon is used for 2 years, no antibodies are formed that neutralize the antiviral activity of recombinant interferon alfa-2b. The use of the drug Viferon can significantly reduce the course doses and the duration of treatment courses with antibiotics, hormones and cytostatics. Features of the administration of the dosage form ensure a prolonged circulation in the blood of interferon alfa-2b.

Indications for use

Candles are intended for use in the case of diseases caused by bacteria. And also with:

• ARVI;
• inflammation of the lungs;
• influenza;
• sepsis;
• Candidiasis;
• mycoplasmosis;
• intrauterine infections;
• meningitis.

In complex treatment, Viferon is prescribed for hepatitis type B, C, D, as well as for hepatitis of a viral origin with simultaneous course of cirrhosis of the liver.

Contraindications

Producer indicated in the instruction among possible contraindications only individual intolerance of substances that make up the drug. It should be noted that preparations based on interferon from foreign pharmaceutical companies have a wide range of contraindications, such as inadequate kidney and liver function, vascular and heart disease, and thyroid problems.

People with these diseases should always consult with a doctor about the possibility of treatment with the drug Viferon without harm to health. It is possible that the doctor will prescribe another remedy for the treatment of influenza. The same applies to the therapy of acute viral infections in pregnant and lactating women who need to be very careful about the choice of medication so as not to harm the child.

Application in pregnancy and lactation

Candles Viferon during breastfeeding may be used to treat bacterial, infectious diseases. Dosage remains the same as for an adult.

Pregnant for a period not earlier than 2 weeks, it is permitted to use suppositories with any content of interferon. Up to 14 days, the use of the drug is not allowed due to the lack of sufficient research.

Pregnant and lactating mothers should not prescribe themselves treatment with Viferon. Only a doctor based on the characteristics of the course of pregnancy, determines: the rate of the drug per day, the dose and duration of admission.

Instructions for use

The instructions for use indicate that Viferon in the form of candles is used rectally.

Acute respiratory viral infections, including influenza, incl. complicated by bacterial infection, pneumonia (bacterial, viral, chlamydial) in children and adults as part of complex therapy:

1. Preterm infants with gestational ages less than 34 weeks are prescribed Viferon 15, 00 IU at 1 suppository 3 times / day 8 hours daily for 5 days. According to clinical indications, therapy can be continued. The break between the courses is 5 days.
2. Children under 7 years, incl. newborn and premature with a gestational age of more than 34 weeks, appoint Viferon 15, 00 IU at 1 suppository 2 times / day after 12 hours daily for 5 days. According to clinical indications, therapy can be continued. The break between the courses is 5 days.
3. The recommended dose for adults, including pregnant women and children over 7 years of age, is Viferon 50, 00 IU per 1 suppository 2 times / day after 12 hours daily for 5 days. According to clinical indications, therapy can be continued.

Infectious and inflammatory diseases of newborn children, incl. preterm, such as meningitis (bacterial, viral), sepsis, intrauterine infection (chlamydia, herpes, cytomegalovirus infection, enterovirus infection, candidiasis, including visceral, mycoplasmosis) as part of complex therapy:

1. Recommended dose for newborns, incl. premature with a gestational age of more than 34 weeks, - Viferon 150 000 IU daily for 1 suppository 2 times / day after 12 hours. The course of treatment is 5 days.
2. Preterm infants with gestational ages less than 34 weeks are prescribed Viferon 15, 00 IU daily for 1 suppository 3 times / day after 8 hours. The course of treatment is 5 days.
3. The recommended number of courses for various infectious and inflammatory diseases: sepsis - 2-3 courses, meningitis - 1-2 courses, herpetic infection - 2 courses, enterovirus infection - 1-2 courses, cytomegalovirus infection -2-3 courses, mycoplasmosis, candidiasis, incl. visceral - 2-3 courses. The break between the courses is 5 days. According to clinical indications, therapy can be continued.

Chronic viral hepatitis B, C, D in children and adults as part of complex therapy, incl. combined with the application of plasmapheresis and hemosorption in chronic viral hepatitis of severe activity complicated by cirrhosis of the liver:

1. The recommended adult dose is Viferon , 0, 00 IU for 1 suppository 2 times / day after 12 hours daily for 10 days, then three times a week every other day for 6-12 months. The duration of treatment is determined by clinical efficacy and laboratory performance.
2. Children under the age of 6 months are recommended 300 000-500 000 ME / day; at the age of 6 to 12 months - 500 000 ME / day.
3. Children aged 1 to 7 years are recommended 3 000 000 ME per 1 m2 body surface area / day.
4. Children over 7 years are recommended 5 000 000 ME per 1 m2 body surface area / day.
5. The drug is used 2 times / day at 12 h the first 10 days daily, then - three times a week every other day for 6-12 months. The duration of treatment is determined by clinical efficacy and laboratory parameters.
6. Calculation of the daily dose of the drug for each patient is made by multiplying the dose recommended for a given age by the surface area body, calculated from a nomogram to calculate the surface area of ​​the body in height and mass according to Garford, Terry and Rourke. Calculation of a single dose is carried out by dividing the calculated daily dose by 2 administrations, the resulting value is rounded to a higher dosage of the suppository.
7. In chronic viral hepatitis of marked activity and cirrhosis of the liver before the conduct of plasmapheresis and / or hemosorption, children under the age of 7 years Viferon 150 000 ME, for children over the age of 7 years - Viferon 500 000 ME per 1 suppository 2 times / day after 12 hours daily for 14 days.

Primary or recurrent herpetic infection of the skin and mucous membranes, localized form, mild and moderate-to-moderate course, incl. urogenital form in adults, including pregnant women:

1. The recommended adult dose is Viferon 1 000 000 IU at 1 suppository 2 times / day after 12 hours daily for 10 days or more with a recurrent infection. According to clinical indications, therapy can be continued. It is recommended to start treatment immediately with the appearance of the first signs of skin and mucous membrane damage (itching, burning, redness). In the treatment of recurrent herpes it is desirable to begin treatment in the prodromal period or at the very beginning of the manifestation of signs of relapse.
2. Pregnant women with the second trimester of pregnancy (starting from the 14th week of gestation) appoint Viferon 500 000 ME per 1 suppository 2 times / day after 12 hours daily for 10 days, then 1 suppository 2 times / day after 12 hours every fourth day for 10 days. Then every 4 weeks before delivery - Viferon 150 000 ME per 1 suppository 2 times / day after 12 hours daily for 5 days. If necessary, it is indicated before delivery (from the 38th week of gestation) of Viferon 500 000 ME per 1 suppository 2 times / day after 12 hours daily for 10 days.

Infectious and inflammatory diseases of the urogenital tract (chlamydia, cytomegalovirus infection, ureaplasmosis, trichomoniasis, gardnerellez, papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis) in adults, including pregnant women as part of complex therapy:

1. The recommended adult dose is Viferon 50, 00 IU at 1 suppository 2 times / day after 12 hours daily for 5-10 days. According to clinical indications, therapy can be continued.
2. Pregnant women with the second trimester of pregnancy (starting from the 14th week of gestation) appoint Viferon 500 000 ME per 1 suppository 2 times / day after 12 hours daily for 10 days, then 1 suppository 2 times / day after 12 hours every fourth day for 10 days. Then every 4 weeks before delivery - Viferon 150 000 ME per 1 suppository 2 times / day after 12 hours daily for 5 days. If necessary, prescribe before delivery (from the 38th week of gestation) Viferon 500000 ME per 1 suppository 2 times / day after 12 hours daily for 10 days.

It is worth knowing that 1 suppository contains, as an active substance, interferon alpha-2b human recombinant in these dosages (15, 00 IU, 50, 00 IU, , 0, 00 IU, , 0, 00 IU).

Side effects

Viferon in the form of an ointment in most cases is well tolerated. Side effects when applied to the nasal mucosa usually have a transient and weak character and disappear on their own after the drug is discontinued.

In extremely rare cases, when using the gel in patients with hypersensitivity, local allergic reactions may develop. When they appear, the treatment is stopped.

In the application of suppositories Viferon in some cases, the development of allergic reactions (itching, skin rashes) is possible. These phenomena are reversible and disappear after 72 hours after discontinuation of therapy.

special instructions

Viferon in the form of suppositories for pregnant women can be used starting from the 14th week of pregnancy.

Drug Interactions

Viferon is well combined with all drugs used in the treatment of viral and other diseases (chemotherapy, antibiotics, glucocorticosteroids).

Reviews

We picked up some reviews of people about the candles Viferon:

1. Sasha. The child was not even a year old when he fell ill. I had to call a doctor who diagnosed ARVI. According to his appointment, they bought Viferon candles. The child had neither a cough nor a cold. Only high temperature disturbed us. The course of treatment was 5 days. In the morning and evening, one candle was inserted. As a result, one package was enough for the entire period of therapy. The candles are injected rectally, but the child did not resist. During treatment, I noticed that a rash appeared on the baby's skin, I was afraid that it was an allergic reaction, but soon everything went away. I can say that the drug helped: the temperature dropped to normal on the third day of treatment.
2. Olga. My children never liked to take powdered medicines for colds. Somehow got with the junior to the doctor with complicated bacterial infections, and we were recommended by Intel-P. There were no candles in the pharmacy, I bought Viferon - I liked the instructions for use. Since then, I use Viferon for the prevention of sores, ARI. Is it an antibiotic or not? I do not know.
3. Julia. In the reviews I read that with mycoplasmosis, a recurrent herpetic infection is prescribed Viferon. The drug is active against infections, bacteria, has no side effects, cheap at a price. I also want to try. I hope that the reviews will not fail. I bought the gel at a price of 160 rubles, tomorrow I'll start applying.
4. Timur. An excellent product. Often we take for our little daughter. It helps a lot - a child rarely gets sick more than 4-5 days. Pick up a pill or syrup, which she agrees to drink, is not always possible. With candles everything is much simpler. The only thing that I do not like is difficult to take with you on the road, since candles should be stored at a temperature of no higher than 10 degrees.

Analogues

With the appointment of Viferon, many patients are interested in cheaper analogs that can replace the drug. Among the analogues of Viferon, the following are the most popular medicines:

• Anaferon
• Genferon
• Kipferon
• Grippferon
• Laferon

Before using analogues, consult your doctor.

Storage conditions and shelf life

Keep candles away from children at a temperature of no more than 10 degrees (preferably in the refrigerator) in the original packaging. Shelf life is 2 years from the date of manufacture. At the end of the expiration date, the drug should be discarded.

How to choose probiotics for the intestine: a list of drugs.

Effective and inexpensive cough syrups for children and adults.

Modern non-steroidal anti-inflammatory drugs.

Review of tablets from the increased pressure of the new generation.

Antiviral drugs are inexpensive and effective.