From this article you will learn: what is the action of magnesia under pressure, which way of its application is preferred to date( oral, through a dropper, intramuscularly).Indications, contraindications, undesirable consequences of such treatment.
Contents of the article:
- The effect of magnesia at
- pressure Indications for magnesium sulfate at
- pressure Possible side effects of
- Contraindications to the use of magnesium
- What can not be combined with magnesium sulfate
- Which method of use is better at high pressure
Magnesium sulfate solution( in common parlance - magnesium)- one of the high-speed drugs used in the hypertensive crisis to lower blood pressure( abbreviated BP) and withdrawal of concomitant symptoms. With a sharp rise in blood pressure, this medicine helps to reduce it quickly, significantly reducing the risk of life-threatening consequences - acute heart failure, heart attack or stroke.
Today, intravenous fluid administration of magnesia is preferred as a rapid reaction preparation. In / in-drip solution is already injected into the hospital. The intramuscular route is considered obsolete, it is rarely used when the patient has bad veins. This is associated with several factors:
- Intramuscular injections of magnesia are very painful.
- To obtain an antihypertensive effect, it is necessary to administer 15-20 ml of the solution, which is quite a lot for the intravenous injection.
- At the injection site often appears a hematoma( bruise, painful tightening of inflammatory tissues) and even an abscess( purulent inflammation of the tissue with the formation of a cavity with pus).
Because of this, it is not recommended to inject intramuscularly by itself. They are prescribed by a cardiologist, a therapist, less often a rheumatologist.
Magnesium sulfate is a symptomatic agent. Despite the considerable relief of complaints accompanying a sharp jump in pressure, he does not treat hypertension, does not eliminate the cause of its occurrence. Therefore, magnesium is not used as a permanent drug for treatment. In the therapeutic or cardiological department of the hospital, he can be appointed by the doctor in / in-drip to stabilize blood pressure, make up for magnesium deficiency, and eliminate arrhythmias.
Magnesia action at
pressure The magnesium sulfate solution has a diuretic, anticonvulsant, soothing, vasodilating action. Depending on the dose of administration, a sedative, hypnotic or even narcotic effect can be achieved. This is possible due to the fact that the active substance of the drug inhibits neuromuscular transmission.
Click on the picture to enlarge Care must be taken, use the medicine only as directed by the doctor and in the strictly recommended dosage. A significant excess of the dose can lead to a number of serious consequences, the most terrible of which is the cardiac arrest due to the suppression of the function of respiration.
In a hypertensive crisis, intramuscular or intravenous administration of 25% magnesia solution leads to the following positive effects:
- coronary artery enlargement by removing spasm of their walls;
- eliminating smooth muscle spasms;
- increased urinary and feces excretion;
- reduction of neural excitation or overexertion;
- normalization of the heart rate;
- elimination of toxic substances from the body.
If you need to provide emergency help, the solution is often injected / in-jet, but slowly at a rate of 1 ml per minute. The therapeutic effect occurs after 15-20 minutes, after the / m introduction - after 55-60 minutes, lasts up to 4 hours.
Indications for the use of magnesium sulfate under pressure
What are the symptoms of magnesia on intravenous administration? Typically, ambulance staff practices IV injection of the following conditions associated with hypertensive crisis:
- pulmonary edema;
- of ventricular arrhythmia, detected during the removal of an emergency ECG;
- muscle cramps;
- neurological symptoms that increase the risk of stroke;
- catecholamine crisis - a sharp increase in blood pressure with autonomic and metabolic disorders in the form of profuse sweating, tremors, disturbances of the heart rhythm, etc.;
- of renal failure;
- Eclampsia of pregnancy with convulsive syndrome - the most severe form of toxicosis.
The latter condition is dangerous for both the future mother and the baby, since it can lead to fetal death, pulmonary edema, premature placental abruption, and a stroke in a pregnant woman. It flows with a loss of consciousness, seizures, even a coma is possible. High risk of miscarriage or premature birth due to hypertension of the uterus. Magnesium sulfate helps to remove muscle and vascular spasm, relax the uterus, lower blood pressure, preventing serious consequences.
Possible side effects when using magnesium sulfate
If a solution enters the adipose tissue with the introduction of an intramuscular injection, an abscess can form, so it is important to inject the medicine strictly into the muscle of the upper outer square of the buttock. Other undesirable consequences are possible with the use of magnesia:
- Weakness.
- Severe sleepiness, deep sleep.
- Dizziness.
- Slow speech. Reddening of the skin of the face.
- Sensation of heat in the area of the chest, head.
- Thirst.
- Diarrhea.
- Doubling in the eyes.
- Nausea, vomiting.
- Spastic abdominal pain.
- Inhibition of breathing with the appearance of dyspnea.
- Allergic reactions.
It should be noted that magnesium sulfate is a mediocre drug that can be used without the control and prescription of a doctor. If the patient has heart or respiratory disease, magnesium can trigger respiratory failure, cardiac arrest and death. Severe soothing effect when the dose is exceeded leads to a condition similar to anesthesia. In some people, instead of a sedative effect, the drug causes hyperactivity, anxiety.
Contraindications to the use of magnesium
- Allergy or hypersensitivity to the active substance.
- Hypotension - low blood pressure.
- Atrioventricular blockade is a partial cessation or obstruction of the passage of an electrical impulse between the ventricles and atria. Because of this, the heart rhythm is broken, various arrhythmias develop with hemodynamic disturbances.
- Renal failure.
- Bradycardia is a rare pulse.
- Before delivery to avoid termination of labor.
- Myasthenia gravis is a disease manifested by muscle weakness.
- Increased level of magnesium in the blood.
- Intestinal obstruction.
- Dehydration of the body( due to diuretic effect).
- Symptoms of appendicitis.
- Bleeding from the rectum.
Use with caution in women during pregnancy and lactation, in patients with respiratory system diseases and heart pathologies.
What can not be combined with magnesium sulfate
Magnesia is incompatible with:
- alcohol;
- with calcium preparations;
- with barium salts;
- clindamycin phosphate;
- carbonates;
- tartrates;
- with salicylates;
- procaine;
- hydrocortisone succinate and some other substances.
When the compounds are combined from the list above with magnesia, a precipitate forms.
With simultaneous reception with anticonvulsant, antiparkinsonian, hypnotic or psychotropic agents, magnesium strengthens their effect. The likelihood of respiratory depression increases when combined with narcotic analgesics, barbiturates, hypotensive drugs. Nifedipine and muscle relaxants enhance the ability of magnesium to provoke neuromuscular blockade.
The action of magnesium weakens the introduction of intravenous potassium salts, so they are used as an antidote for overdose, and ciprofloxacin reduces its absorption( absorption).
Which way is better to apply magnesia at pressure
Magnesium sulfate for lowering blood pressure is better to inject intravenously-drip or jet, and not intramuscularly.
Gradual intravenous infusion - the most optimal way of magnesia therapy Oral reception with hypertensive crisis does not justify itself. The diluted magnesia powder, drunk inside, gives choleretic, laxative, spasmolytic effect. This method is used to eliminate stagnation of bile, purify the intestines, eliminate toxins and poisons, relieve spasm and pain in the abdomen.
The best solution of magnesium sulphate is administered through a dropper. A slow, gradual increase in the concentration of the drug in the blood gives the desired therapeutic effect without the development of unwanted side-effects. Doctors of ambulance often practice IV injection of the drug, but clearly control its speed, and also focus on the emerging sensations in the patient.
