Which drug is better: Corinfar or Kapoten

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From this article you will learn about Corinfar or Kapoten - which is better for treating a number of cardiac diseases. Is it always possible to replace one drug with another, and who decides this question. Pathological conditions, in which one means helps and no other is prescribed. Consolidated comparative tables.

Contents of the article:

  • Indications for use of both
  • Mechanisms of action of Corinfar and Kapoten
  • Side effects of
  • When it is not possible to prescribe medications
  • Summary: in what situations which drug is better

Corinfar is the trade name of the active substance Nifedipine. The form of release - tablets. It blocks slow calcium channels in the muscle cells of the heart and the walls of the vessels, having an effect with increasing blood pressure and angina pectoris.

Kapoten is a pharmacological preparation, the main component of which is Captopril. It is released in tablets. It blocks the angiotensin-converting enzyme, has a therapeutic effect in hypertension, cardiac muscle disruption, renal pathology on the background of diabetes mellitus.

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It's impossible to say unequivocally that one drug is better than another. Despite the overall effect in the action on blood pressure, it is realized in different ways. In deciding whether to prescribe a specific medication,

  • takes into account the patient's individual reaction to the drug - Corinth is the one that helps the better, and the other - Kapoten;
  • the need for a combination with other drugs - consider the frequency of admission and the combined effect;
  • the presence of complications of hypertension( myocardial infarction, chronic myocardial insufficiency) or concomitant somatic pathology( diabetes, angina pectoris).

Both drugs have good tolerability and high efficiency. The final decision on the appointment of any of these drugs is taken by the therapist or cardiologist, taking into account the specific clinical situation and the individual characteristics of the patient.

Corinfar and Kapoten are medicines that can not be used without medical advice.

Next we will compare these drugs in detail.

Indications for the assignment of both agents

Pathological process or disease Kapoten Corinfar
Hypertonic disease + +
Stenocardia and / or variant - +

( in combination with other drugs)

Chronic heart failure +

in combination with other drugs)

-
Left ventricular failure after infarction + -
Kidney failure( nephropathy) in the background of type 1 diabetes + -

Mechanism of action of Corinfar and Kapoten

have effects Capoten Corinfar
relaxes the walls of blood vessels + +
relaxes the walls of the veins + -
decreases blood pressure + +
decreases the pressure in the pulmonary arteries and right heart + -
Decreases selectionof aldosterone by the adrenal glands + -
Increased blood flow in the heart arteries and areas with blood flow disorders - +
Restores heart rate - +

(effect low)

Renal blood flow strengthening - +
Ischemia of the myocardium

Time intervals of action

Intervals Kapoten Corinfar
Effects of the drug after ingestion 30 min - 1 hour 20-40 min
Effect duration 4-6hours 4-6 hours
Generation of drug resistance - 2-3 months of continuous admission
Medication regimen 2-3 times per day 2-3 times daily

Side effects of

preparations
organ system or type reaction Side effects descending frequency of occurrence
Capoten Corinfar
Cardiovascular arrhythmias

Angina

significant pressure reduction

Hot flashes

Cardiogenic shock

Cardiac

arrhythmias

Edema

Marked reduction in pressure

Hot flashes

Fainting

Myocardial infarction

Nervous system Drowsiness

Dizziness

Insomnia

Depression

Trembling limbs( tremors)

impaired blood flow in

brain confusion

sensitivity Violation

Headache

Dizziness

Drowsiness

Fatigue

Tremor

gait disturbance

Dysphagia

sensitivity Violation

Depression

Respiratory Dry cough

Dyspnea

Narrowingbronchi( bronchospasm)

Rhinitis

Pulmonary edema

Bronchospasm

Pulmonary edema

Skin, its elements, allergic rhinitisshares Itching

rash

prolapse

hair Angioedema

Itching

rash

Dermatitis

Anaphylactic reactions

hematopoiesis Reducing the number of individual blood cells, or all at once

Lymphadenopathy

Reducing the number of individual blood cells, or all at once
immune systemAutoimmune diseases -
Digestive system Nausea

Vomiting

Abdominal pain

Gastritis

Chair disorder( constipation, diarrhea)

Dry mouth

Ulcers in the oral cavity

Liver inflammation

Nausea

Constipation disorder

Increased gas generation

Dryness of the mouth

Thickening of the gums

Liver inflammation

Musculoskeletal system Muscle achesor joints Muscle or joint pain

Joint edema

Convulsions

Urinary system Renal impairment

Increased or decreased urine output

Pain with urination

Renal impairment

Increased urine output

Reproductive system Impotence

Increased mammary glands in men

Increased mammary glands in men

Breast discharges from

Heart rhythm disorders by type of atrial fibrillation

When medication

can not be administered
Contra Capoten Corinfar
Any allergic reaction to the drug in the past + +
Severe impairment of renal function + Precautions
Severe liver failure + Precautions
Sustained high potassium level + -
stenosis of renalarteries, transplanted or single kidney + -
Lactose intolerance, its deficiency + -
Pregnancy + First trimester
Feedof breast + +
age of 18 + +
Low blood pressure of any origin + +
insufficient work heart - +
Acute myocardial - +
aortic stenosis - +

Conclusion

General Drug Quality:

  1. High efficiency with first use.
  2. Fast effect after resorption under the tongue( used to relieve the hypertensive crisis).
  3. Good tolerability( side effects occur infrequently).
Negative qualities of Kapoten Negative qualities of Corinphar
Dry cough - a frequent side effect Narrow range of indications for use of
No extended dosage forms - for necessary therapeutic effect, reception up to 3 times per day is necessary Rapid development of body resistance( tolerance)
In general, morecontraindications and side effects of

Despite the listed disadvantages of each of the drugs, it can not be unequivocally said that one of them is better than the other- everything is decided by the specific clinical situation, the features of the disease and the general condition of the patient.