Which drug is better: Corinfar or Kapoten

From this article you will learn about Corinfar or Kapoten - which is better for treating a number of cardiac diseases. Is it always possible to replace one drug with another, and who decides this question. Pathological conditions, in which one means helps and no other is prescribed. Consolidated comparative tables.

Contents of the article:

• Indications for use of both
• Mechanisms of action of Corinfar and Kapoten
• Side effects of
• When it is not possible to prescribe medications
• Summary: in what situations which drug is better

Corinfar is the trade name of the active substance Nifedipine. The form of release - tablets. It blocks slow calcium channels in the muscle cells of the heart and the walls of the vessels, having an effect with increasing blood pressure and angina pectoris.

Kapoten is a pharmacological preparation, the main component of which is Captopril. It is released in tablets. It blocks the angiotensin-converting enzyme, has a therapeutic effect in hypertension, cardiac muscle disruption, renal pathology on the background of diabetes mellitus.

It's impossible to say unequivocally that one drug is better than another. Despite the overall effect in the action on blood pressure, it is realized in different ways. In deciding whether to prescribe a specific medication,

• takes into account the patient's individual reaction to the drug - Corinth is the one that helps the better, and the other - Kapoten;
• the need for a combination with other drugs - consider the frequency of admission and the combined effect;
• the presence of complications of hypertension( myocardial infarction, chronic myocardial insufficiency) or concomitant somatic pathology( diabetes, angina pectoris).

Both drugs have good tolerability and high efficiency. The final decision on the appointment of any of these drugs is taken by the therapist or cardiologist, taking into account the specific clinical situation and the individual characteristics of the patient.

Corinfar and Kapoten are medicines that can not be used without medical advice.

Next we will compare these drugs in detail.

Indications for the assignment of both agents

Pathological process or disease	Kapoten	Corinfar
Hypertonic disease	+	+
Stenocardia and / or variant	-	+ ( in combination with other drugs)
Chronic heart failure	+ in combination with other drugs)	-
Left ventricular failure after infarction	+	-
Kidney failure( nephropathy) in the background of type 1 diabetes	+	-

Mechanism of action of Corinfar and Kapoten

have effects	Capoten	Corinfar
relaxes the walls of blood vessels	+	+
relaxes the walls of the veins	+	-
decreases blood pressure	+	+
decreases the pressure in the pulmonary arteries and right heart	+	-
Decreases selectionof aldosterone by the adrenal glands	+	-
Increased blood flow in the heart arteries and areas with blood flow disorders	-	+
Restores heart rate	-	+ (effect low)
Renal blood flow strengthening	-	+

Ischemia of the myocardium

Time intervals of action

Intervals	Kapoten	Corinfar
Effects of the drug after ingestion	30 min - 1 hour	20-40 min
Effect duration	4-6hours	4-6 hours
Generation of drug resistance	-	2-3 months of continuous admission
Medication regimen	2-3 times per day	2-3 times daily

Side effects of

preparations

organ system or type	reaction Side effects descending frequency of occurrence
Capoten	Corinfar
Cardiovascular	arrhythmias Angina significant pressure reduction Hot flashes Cardiogenic shock Cardiac	arrhythmias Edema Marked reduction in pressure Hot flashes Fainting Myocardial infarction
Nervous system	Drowsiness Dizziness Insomnia Depression Trembling limbs( tremors) impaired blood flow in brain confusion sensitivity Violation	Headache Dizziness Drowsiness Fatigue Tremor gait disturbance Dysphagia sensitivity Violation Depression
Respiratory	Dry cough Dyspnea Narrowingbronchi( bronchospasm) Rhinitis Pulmonary edema	Bronchospasm Pulmonary edema
Skin, its elements, allergic rhinitisshares	Itching rash prolapse hair Angioedema	Itching rash Dermatitis Anaphylactic reactions
hematopoiesis	Reducing the number of individual blood cells, or all at once Lymphadenopathy	Reducing the number of individual blood cells, or all at once
immune	systemAutoimmune diseases	-
Digestive system	Nausea Vomiting Abdominal pain Gastritis Chair disorder( constipation, diarrhea) Dry mouth Ulcers in the oral cavity Liver inflammation	Nausea Constipation disorder Increased gas generation Dryness of the mouth Thickening of the gums Liver inflammation
Musculoskeletal system	Muscle achesor joints	Muscle or joint pain Joint edema Convulsions
Urinary system	Renal impairment Increased or decreased urine output Pain with urination	Renal impairment Increased urine output
Reproductive system	Impotence Increased mammary glands in men	Increased mammary glands in men Breast discharges from

Heart rhythm disorders by type of atrial fibrillation

When medication

can not be administered

Contra	Capoten	Corinfar
Any allergic reaction to the drug in the past	+	+
Severe impairment of renal function	+	Precautions
Severe liver failure	+	Precautions
Sustained high potassium level	+	-
stenosis of renalarteries, transplanted or single kidney	+	-
Lactose intolerance, its deficiency	+	-
Pregnancy	+	First trimester
Feedof breast	+	+
age of 18	+	+
Low blood pressure of any origin	+	+
insufficient work	heart -	+
Acute myocardial	-	+
aortic stenosis	-	+

Conclusion

General Drug Quality:

Negative qualities of Kapoten	Negative qualities of Corinphar
Dry cough - a frequent side effect	Narrow range of indications for use of
No extended dosage forms - for necessary therapeutic effect, reception up to 3 times per day is necessary	Rapid development of body resistance( tolerance)
In general, morecontraindications and side effects of

Despite the listed disadvantages of each of the drugs, it can not be unequivocally said that one of them is better than the other- everything is decided by the specific clinical situation, the features of the disease and the general condition of the patient.