Trimedate

Trimedat is a medicament of Russian manufacture - the company of Valenta Farma.

The drug contains an active ingredient called trimebutine maleate, which regulates intestinal peristalsis. The drug is intended for restoration of the digestive tract, facilitating the process of emptying the intestine. It has a strong antispasmodic effect.

The efficacy of trimmedate has been demonstrated in a number of randomized trials. For example, in the treatment of irritable bowel syndrome, it was about 83%, which allows considering this drug as a universal regulator of the motor function of the gastrointestinal tract.

Clinical and pharmacological group

An agent regulating the peristalsis of the gastrointestinal tract. It is believed that the effect of trimebutin is due to the effect on the opioid receptors of the gastrointestinal tract.

Terms of sale from pharmacies

Can buywithout a doctor's prescription.

Price

How much does Trimedate cost in pharmacies? The average price is at the level of240 rubles.

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Composition and form of release

Manufacturers produce the drug in the form of tablets containing 100 or 200 mg of the active ingredient trimebutin. In the secondary packaging (carton) there are contour cells and an abstract. Tablets are provided with risks for convenient dosing. As ingredients in the composition of the dosage form are:

colloidal silicon dioxide;
corn starch;
milk sugar;
magnesium stearate;
talc.

With the help of auxiliary components, a tablet is formed and the necessary absorption of the active substance by the gastric walls is ensured.

pharmachologic effect

Trimedate regulates the motor function of the gastrointestinal tract, as well as its visceral sensitivity by relaxing and contracting the smooth musculature of the intestine. The drug helps faster and easier to empty the intestines by easing the pressure of the esophageal sphincter. This helps to restore the physiological activity of the musculature of the intestine.

The use of Trimedate allows timely response of the smooth muscles of the large intestine to food that is difficult to digest. Rapid and productive absorption of the drug allows him to effectively impact the entire length of the digestive tract.

The maximum concentration is achieved 2 hours after the application of the drug. Metabolized Trimedate in the liver, and is excreted in the urine in the form of unchanged metabolites.

Indications for use

What helps? Trimedate is used in the following situations:

Dyspeptic disorders and their manifestations in the form of nausea and vomiting.
Gastroesophageal reflux disease.
Complex preparation for endoscopic or roentgenological examination of the stomach and intestines.
Various gastroduodenal disorders: pain in the stomach and intestines, digestive disorders, feeling of stomach overflow.
Irritable bowel syndrome, manifested by pain in the abdomen, intestinal spasms, stool disorders, constipation and diarrhea.
Dyspeptic diseases and disorders in children are caused by a violation of normal motor activity of the stomach and intestines.

Contraindications

The only absolute medical contraindications for the use of the Trimedat tablets are individual intolerance of the active or auxiliary substances of the drug, as well as the patient's age is less than 3 years. Before using the drug, medical contraindications should be excluded.

Intended use for pregnancy and lactation

In the course of experimental studies on animals, Trimedata had no negative effects on the fetus and course of pregnancy. However, similar tests for understandable ethical reasons were not performed in pregnant women, so there is no precise data on the safety of the drug. This is why it is not recommended to take Trimedate during the first trimester of pregnancy (from the beginning to the end of the 13th week). And in Trimester II and III Trimedat can only be taken if the potential benefit exceeds all possible risks.

Since it is not known whether Trimedate penetrates into female milk, it is recommended that the drug be withdrawn throughout the entire breastfeeding period of the baby. If it is necessary to take Trimedat for health reasons, then the child should be weaned and transferred to artificial mixtures.

Dosage and route of administration

As indicated in the instructions for use of the tablet, trimedate should be swallowed whole and washed down with a significant amount of water. Adults and children over the age of twelve, trimedate is administered orally 100-200 mg three times a day. To prevent the relapse of irritable bowel syndrome after the course of therapy, during remission, should continue taking medication at a therapeutic dose of 300 mg per day for twelve weeks.

Children aged five to twelve years are prescribed 50 mg of the drug three times a day, children aged three to five years - 25 mg of the drug three times a day.

According to the instructions, the use of Trimedate in the form of a suspension is assigned according to the following scheme:

children under half a year - half a teaspoon two or three times a day;
children from six months to a year - one teaspoon twice a day;
from one to five years - one teaspoon three times a day;
children older than five years - two teaspoons three times a day;
adults - two tablespoons three times a day.

Side effects

Trimedate can cause the following side effects in children and adults:

Dizziness;
Headache;
Anxiety;
Skin rash;
Dry mouth;
Unpleasant taste in mouth;
Diarrhea;
Nausea;
Constipation;
Drowsiness;
Fatigue;
Retention of urine;
Violations of the menstrual cycle;
Painful increase in the volume of mammary glands.

Overdose

To date, in clinical practice cases of overdose of the tablets Trimedat were not registered.

special instructions

Do not exceed the dose. To get rid of some pathological conditions requires a fairly long treatment, which includes and supportive therapy. Trimedate refers to non-prescription drugs, so it can be the drug that will be in the home medicine chest and used by all family members.

Trimedate does not weaken the central nervous system, so it does not exclude the possibility of driving a vehicle and other mechanisms.

Interaction with other drugs

The use of zotepin may lead to an extension of the anticholinergic effect. An increase in the duration of action of d-tubocurarine was recorded.

Reviews

We offer you to get acquainted with the opinions of people who used the drug Trimedat:

Svetlana. Good tablets. Their friend advised me. I began to complain to her of the heaviness, the pain in my stomach after eating. So now if such discomfort appears, then immediately begin to take Trimedat. TTT bloating and pain pass, even belching, if present, stops.
Alexey. I suffer from a chronic gastritis for ten years already. Most drugs and treatment methods not only did not eliminate the problem, but do not even always eliminate stomach pain. Taking Trimedat, I almost forget about pain. It is a pity that you can use it only with long interruptions.
Anna. The doctor prescribed these pills for me after the gastrointestinal and gastrointestinal tract. I complained of nausea after eating, heaviness in the stomach and discomfort. I took them a little over two weeks half an hour before meals 3 times a day. They helped me - nausea began to disappear and well-being improved.

The doctors' comments about Trimedat are overwhelmingly positive, which is due to several factors. The fact is that doctors form their opinion on the drug, based on the following characteristics:

What percentage of patients and with what severity of the course of the disease receives a good therapeutic effect of the drug;
What percentage of patients is well suited to the drug, that is, does not cause severe and painful side effects;
What percentage of patients can afford to use the drug for financial opportunities.

Doctors consider the drug to be good and, accordingly, respond positively to it, if it is sufficiently universal. A drug is considered to be universal, which is well tolerated and gives a good therapeutic effect in most patients, including number in the severe course of the disease, as well as not too expensive, so that almost everyone can afford it. For all these parameters, Trimedate fits into the universal drug, and, therefore, is good in the opinion of doctors. That is why most of the reviews about it from the doctors are positive.

Analogues

Synonyms of Trimedate are drugs that also contain trimebutin as an active ingredient. On the domestic pharmaceutical market, there are the following drugs-synonyms of Trimedat: