Itomed: instructions for use

Itomed has the ability to positively affect the tone and motility of the gastrointestinal tract.

The main active ingredient is hydrochlorideptopride. It is a dopamine receptor antagonist and is able to inhibit acetylcholinesterase, in addition it suppresses the destruction of acetylcholine. This leads to increased motor function of the intestine.

On this page you will find all information about Itomed: full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Itomed. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

A drug that improves the tone and motility of the digestive tract. Stimulator of the release of acetylcholine.

Conditions of leave from pharmacies

Available without a prescription.

Price list

How much is Itomed? The average price in pharmacies is at the level of400 rubles.

Form of issue and composition

Composition per 1 tablet

1. Active substance: Teopride hydrochloride - 50.00 mg
2. Excipients: lactose monohydrate core - 74.68 mg, corn pregelatinized corn starch - , 0 mg, croscarmellose sodium - 1.80 mg, silicon dioxide colloid - 1.00 mg, magnesium stearate - 2.52 mg; core mass - 135.00 mg shell of opadrai 85F18422 white - 3.00 mg (polyvinyl alcohol, partially hydrolyzed - , 00 mg, titanium dioxide - , 50 mg, macrogol 4000 - , 06 mg, talc - , 44 mg).

The drug is available in the form of white round tablets, packed in blisters of 7 - 14 pieces.

Pharmacological effect

Tablets of Itomed increase the tone and motility of the gastrointestinal tract, stimulating the release of acetylcholine.

The drug has an antiemetic property, which is provided by the interaction of D 2 -receptors. The suppression of the emetic reflex occurs due to the formation of apomorphine and the activation of gastric motility. The drug has an effect on the upper sections of the gastrointestinal tract, accelerates its release. After taking the drug, the active substance is completely absorbed into the total blood flow from the upper gastrointestinal tract and its distribution in the tissues.

The metabolism of the active substance occurs in the liver, and the withdrawal of the products of disintegration occurs in the urine.

Indications for use

Indications for receiving Itomed may be the following deviations diagnosed by a specialist:

• heartburn;
• indications for gastralgia (intense pain in the stomach);
• a feeling of nausea and vomiting;
• general worsening of the condition against pain in the stomach and intestines;
• flatulence;
• anorexia.

Contraindications

Most pharmacy products have their own list of restrictions to admission. Among the absolute and relative contraindications to proketinics of "Itomed" in the attached instruction are indicated the following:

• congenital insufficiency of lactose;
• the moment of intrauterine development of the fetus;
• different etiology of bleeding of their GIT structures;
• mechanical form of obstruction;
• perforation of intestinal loops;
• children's category of patients;
• individual hypersensitivity to the active or auxiliary components of the drug "Itomed", from which these tablets can cause allergies.

With extreme caution, the drug is recommended for the elderly, as well as people with reduced activity of the liver structures, as well as kidneys.

Application in pregnancy and lactation

Is it possible to use "Itomed" (tablets) during the gestation? Instructions for use, reviews, descriptions of this medication state that itprioprida hydrochloride is contraindicated in pregnancy.

One can not help saying that when taking this drug in therapeutic dosages, its active substance is insignificant, but still penetrates into the mother's milk. That is why after the appointment of this drug should stop lactation.

Instructions for use

In the instructions for use, it is indicated that the Itomed tablets are taken orally, before meals.

• Recommended dosing: 1 pc. 3 times a day, the maximum daily dose - 150 mg (3 tablets).
• Elderly patients should be reduced in dose.

If you skip the next dose in the future, the tablets should be taken at regular intervals, avoiding the use of a double dose to compensate for the missed dose.

Side effects

From the central nervous system:

• tremor (trembling of hands);
• headaches of varying intensity;
• dizziness;
• sleep disorders;
• outbursts of irritability.

Side effects in the digestive system include:

• nausea;
• pain in epigastrium;
• stool disorders;
• increased salivation;
• jaundice (skin coloring in yellow due to increased bilirubin concentration in the blood).

From the hematopoietic system:

• leucopenia - a decrease in the number of leukocytes;
• thrombocytopenia - a decrease in the number of platelets.

Possible allergic reactions:

• angioedema;
• hives;
• anaphylactic shock.

From the endocrine system:

• hyperprolactinemia - increasing the amount of prolactin (a substance synthesized by the pituitary);
• gynecomastia - an increase in the size of the mammary glands in men.

The occurrence of at least one of the side effects listed above should be the reason for the immediate discontinuation of the drug and consultation with the attending physician.

Overdose

In the event that the patient has taken an increased dose of medication, then he is washed with the stomach, and also performs symptomatic therapy.

special instructions

Manifestation of symptoms of gynecomastia and galactorrhea requires immediate interruption or complete cessation of treatment.

During the treatment of primary biliary cirrhosis, transient decompensation of liver cirrhosis, which disappears on its own after the drug is discontinued, is possible.

Drug Interactions

1. M-holinoblokatory reduces the effectiveness of tared.
2. Anti-ulcer drugs such as cimetidine, ranitidine, terrenone and cetraxate do not affect the prokinetic efficacy of taupeep.
3. No interaction was found with the simultaneous administration of tesentrop with warfarin, diazepam, diclofenac, ticlopidine, nifedipine, and nicardipine.
4. Metabolic interaction at the level of isoenzymes of the CYP450 system is not expected, since the metabolism of ittopride occurs mainly through flavin monooxygenase.
5. The cholinergic effect of ittopride may be enhanced by the simultaneous use of m-cholinomimetics, as well as cholinesterase inhibitors.
6. Itoprids strengthens the motility of the stomach, which can affect the absorption of drugs when administered together. Particular care should be taken when taking drugs with a narrow therapeutic index, drugs with prolonged release of the active substance or preparations with an enteric coating.

Reviews

We picked up some feedback from people about the preparation of Itomed:

1. Nastya. Itomed. This word I learned when a doctor diagnosed anorexia. Previously, I was diagnosed with only relatives! Therefore, I was scared, it seemed to me that everything was in order! I urgently bought the drug, I started it! In large quantities! So the result is obvious))) My weight has increased by almost 10 kilograms!
2. Oksana. Sometimes there is bloating, and somehow I was advised by "Itomed", and frankly, he helped me very quickly, after a short time the swelling passed, and my stomach normalized its work. This drug is good for heartburn and for a long time could not find a drug that will help with heartburn, very famous and untwisted "Rennie" did not help me, and this drug is enough for one tablet, and the heartburn was taken off like a hand. Of course, the price policy is not very acceptable, I wanted it to be more accessible.
3. Victoria. The doctor diagnosed me with anorexia and appointed Ithomed. The drug was purchased at the pharmacy. The price is quite acceptable. The effect of the medicine proved: I managed to gain almost 10 kilograms. We must strictly follow the instructions. No side effects were observed.

At the forums devoted to the discussion of effective drugs that have the ability to adjust the activity of the intestine, the feedback of people who have completed the course of taking Prokinetics by Itomed is ambiguous. Most of them are positive - the drug has successfully coped with the task - a sense of discomfort, nausea completely eliminated. The medicine coped with gastralgia and lack of appetite. Other reviews indicate that a pronounced positive effect was not observed - dyspepsia persisted.

Analogues

Structural analogs for the active substance:

• Ganaton;
• Itopra.

Before using analogues, consult your doctor.

Storage conditions and shelf life

The shelf life of the Itomed tablets is 3 years. They should be stored in a dry, protected from light and out of reach of children at an air temperature ranging from +15 to +25 ° C.

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