From this article you will learn: what therapeutic effects venotonics have in varicose veins, the indications for their use. What drugs are most effective, and whether it is possible with their help to completely solve the problem of varicose veins.
Contents of the article:
- The description of the venotonics, how they work
- The main indications for the use of
- The names and characteristics of the most effective drugs
- Contraindications and side effects of
- What effect to expect from treatment with phlebotonics
Venotonics( phlebotonics) is a group of medicines whose effect is directed tostrengthening of venous vessels and improvement of blood circulation in them. Such therapeutic effects make these drugs one of the main components of complex treatment for patients with varicose veins and chronic venous insufficiency of the lower extremities.
They can not completely cure this pathology, but you can reduce the severity of symptoms and prevent the occurrence of more severe manifestations. Modern venotonics are practically harmless to the body and well tolerated by all patients.
Veins of the lower extremities are basic, but not the only vessels affected by phlebotonia. They also strengthen the venous plexus of the pelvis and rectum, which allows them to be used for the treatment of pelvic varicose veins and hemorrhoids. Other forms of varicose veins( esophagus and testicle) can not be treated with venotonic drugs.
The appointment of drugs in the treatment of leg and pelvis varicose, choice of dose and control of the effectiveness of the doctors engaged in vascular surgeons and general surgeons. Treatment of enlarged hemorrhoidal veins with venotonicks is prescribed by proctologists and general surgeons.
Description of venotonics, how they function
The venotonics restore the broken structure and strengthen the weakened walls and valves of the veins. Venonizing drugs improve the outflow of blood and lymph from the lower limbs and reduce stagnation in the venous and lymphatic vessels. They eliminate the phenomena of lymphovenous insufficiency, which underlies trophic disorders and destruction of the tissues of the lower limbs.
Mechanisms of action of phlebotonics are as follows:
- Direct restoration, strengthening, increase of the tone of the walls and valves of veins, which narrows them in the area of varicose dilated areas.
- Reduction of the inflammatory process in the walls of venous vessels, which prevents destructive changes in them.
- Reduces the viscosity of venous blood, which prevents the formation of thrombi in the lumen of the veins.
- Normalization of the tone of the capillaries and the smallest lymphatic ducts, which improves the blood supply of tissues and reduces their edema.
Modern venotonics have therapeutic effects not only on the veins, but also on the vessels of the microcirculatory channel( capillaries and lymphatic ducts) in the region of the lower limbs. They do not strengthen the arteries of the legs and do not affect the blood circulation in them.
The main indications for the use of
Venotonics are indicated for the treatment and prevention of such diseases and conditions:
- Varicose disease of the lower extremities: dilated veins, spider veins, large varicose nodules.
- Thrombophlebitis of superficial and deep veins on the legs.
- Postthrombophlebitic syndrome.
- Chronic venous insufficiency of the lower extremities, regardless of the severity and cause of the occurrence( heaviness and swelling of the legs, brown and cyanotic spots, redness and long-lasting wounds on the skin of the lower legs).
- Lymphostasis - lymphatic stasis( pronounced edema of the legs and feet), caused by the defeat of deep veins and lymph vessels after acute purulent inflammatory processes( erysipelatous inflammation, fasciitis).
Thrombophlebitis - venous inflammation with thrombus formation Names and characteristics of the most effective
preparations All venotonic drugs are available in tablets and forms for topical application to the varicose veins area. The general classification of the most effective modern drugs is given in the table.
| flebotonikov Groups and active substances | Names tablets and capsules | Names ointments and gels |
|---|---|---|
| Flavonoids containing diosmin, hesperidin | Detraleks, Phlebodia, Venodiol, Diovenor | There |
| Rutazoidy troxerutin | Troxevasin, Anavenol, Venoruton, Troxerutin | Troxevasin, Venoruton |
| Derived escin from horse chestnut | Drops Escuzan, Escudite | Venitane, Esquevene |
| Plant and Combination Products | Cyclone-3 fort( vitamin C, needle extract, hesperidin) | Cyclo-3 Cream |
| Ginkor Fort( Ginkgo biloba, troxerutin, heptaminol) | Ginkor gel |
According to multicenter studies, the most effective venotonic with leg varicose are preparations containing diosmin( Detralex, Flebodia, Venodiol).But which of these medicines is the most effective, can not be unequivocally stated. The choice of the drug depends on the experience and beliefs of the doctor, and the result of treatment - on the individual characteristics of the patient and the pathology, about which he is appointed. No less important point is that the medicine should be quality, not counterfeit, really released by the original firm.
Detralex
One of the most frequently prescribed venotonics is detralex. The popularity of the drug is explained by several points:
- Long-term existence in the pharmaceutical market.
- Positive feedback from patients regarding efficacy and good tolerability.
- The presence of not only diosmin, but also hesperidin, which enhances its effect.
- The rapid onset of the therapeutic effect, which is most often noted by patients with varicose legs of 1-2 degrees and acute hemorrhoids, especially when taking a shock dose of the drug.
- Relatively affordable price.
Additional features Detralex - the need for double intake per day and large sizes of tablets, which makes it difficult to drink them in some patients.
Flebodia
The main competitor of Detralex is the preparation Flebodia. Its popularity is due to such features:
- Contains only diosmin, but at the highest dose compared with other flavonoids.
- The effect is gradual, but lasting, which is best for patients with chronic stable course of venous pathology of the lower extremities and hemorrhoids.
- The active substance is released from the intestine during the day, which allows taking the drug once a day.
Despite the relatively high price of Flebodia is one of the favorite phlebotonics drugs both among specialists and among patients.
Troxevasin and Escuzan
Virtually identical venotonic agents - derivatives of routine( Troxevasin) and escin of horse chestnut( Escuzan).Although there is nothing in common between these preparations, they are united by such features:
- a slow onset and short duration of the therapeutic effect;
- two or three times a day;
- moderately strong strengthening effect on the venous wall;
- no positive effect on capillaries and microcirculation;
- is the largest application experience( decades);
- availability due to the low price.
The most important advantage of Troxevasin and preparations based on horse chestnut is the presence of both tableted and ointment-gel forms( Troxevasin, Venitan).This allows you to strengthen the effect of the active substance due to the general effect on the venous wall through the blood and local strengthening by applying to the skin of the legs.
Cyclo-3 Fort
Another venotonic, which is worth a separate stay - the drug Cyclo-3 fort. The components that make up it( a small dose of hesperidinum, needles and vitamin C) provide a really good strengthening effect on the venous wall, capillaries and lymphatic ducts. Cyclo-3 fort is slightly weaker than Detralex and Flebodia, but stronger than Troxevasin and Escuzana.
The most important advantage of the drug Cyclo-3 fort is the possibility of using in leg varicose for any period of pregnancy. It can also be used to treat exacerbations of hemorrhoids in pregnant women.
Contraindications and side effects of
In general, all venotonicks are equally well tolerated by patients and rarely cause side effects. If they arise, they are rather related not to the harmful properties of the drug, but to the individual intolerance of its components. It can be:
- Allergic reactions in the form of skin rash and itching, exacerbation of chronic dermatological problems.
- Nausea, vomiting, abdominal pain and other manifestations of irritant effects on the mucous membranes of the stomach and intestines.
- Headache and dizziness.
Therefore, the absolute contraindication for venotonics treatment is one thing - any side effects or poor tolerance of a particular drug. In this case, the agent can be replaced with an analog with an identical or other active substance. In the presence of problems with the gastrointestinal tract, liver and kidneys, venotonics are not contraindicated, but the need and specific features of the use must necessarily be decided by the attending physician.
Side effects of phlebotonics According to generally accepted recommendations, it is better to abstain from using venotonics during pregnancy. Although no harmful effects on the fetal organism have been recorded in the studies, no special indication is given. The most suitable preparation is Cyclo-3 fort, which is characterized by an optimal ratio of potential benefit and harm.
What effect to expect from treatment with phlebotonics
It is impossible to cure of leg varicose with the help of venotonic alone. These drugs, although important, but not the only component of treatment. This means that by themselves they can not completely solve the problems with the veins of the legs. They reduce the severity and speed of progression of pathological changes.
How effective are the venotonics in varicose veins, depends on the degree of expansion and the condition of the veins and the severity of the manifestations of lymphovenous insufficiency of the legs. The weaker the venous wall, and the more it is expanded - the less possibility to restore its structure. Irreversible skin changes in the form of trophic disorders and ulcers, lymphostasis, venous eczema can not be completely eliminated.
Varicose veins and grade 1 venous insufficiency can be almost completely eliminated by venotonicks in combination with the recommendations for a lifestyle and elastic compression of the legs in 80-90%.At 2 degrees the effectiveness of such therapy is not more than 50-60%, with the third - 30-40%, which indicates the inevitability of the operation.
The main rule of venotonic treatment is the systematic intake of courses lasting from one to 2-3 months 2-3 times a year. Venotonizing drugs will not have a full effect if taken only a few days. Any varicose veins is a chronic disease, therefore, course therapy with venotonicks should be carried out throughout life. The solution of the questions concerning the choice and dose of the drug, frequency and duration of admission is better entrusted to the specialist!
