Xsefokam: instructions for use. injections, ointment, tablets

What helps Ksefokam? Instructions for use

Anti-inflammatory and analgesic agents are injections and pills Xsefokam.

What helps this medicine? The drug is prescribed for relief of pain syndrome and symptomatic therapy of rheumatic diseases.

Medication Ksefokam instructions for use suggest using for spondylitis, gout, arthritis.

Composition and form of release

Produce white oblong tablets (4 mg dosage) with an engraved inscription LO4, White oblong tablets (8 mg dosage) with an engraved LO8 inscription.

Also, a lyophilizate is made to produce a solution that is a dense yellow mass. There are no other forms of the drug, be it cream ointment or gel.

Tablets Xefokam, from which it helps with pain, can include 4 or 8 mg lornoxicam. Auxiliary components are: povidone K25, magnesium stearate, cellulose, talc, croscarmellose sodium, lactose monohydrate, titanium dioxide, macrogol 6000, hypromellose.

One vial with lyophilizate contains 8 mg of lornoxicam and additional elements.

Pharmacological properties

In accordance with the instructions to Xefokam, this drug has an analgesic and anti-inflammatory effect. The anti-inflammatory effect of lornoxicam is due to the fact that this substance inhibits the activity of cyclooxygenase isoenzymes, thereby inhibiting the synthesis of prostaglandins.

It also suppresses the release of activated free radicals by leukocytes.

The analgesic effect of tablets and injections of Xsefokam, which increases the safety of its use, is not associated with drug effects.

After ingestion of Xsefokam tablets, the instruction for use reports this, the active substance is rapidly absorbed from the gastrointestinal tract and completely metabolized in the liver. The drug is excreted in the form of metabolites mostly with bile, in part with kidneys.

Injections, pills Xefokam: what helps the medicine

Indications for the use of tablets:

• short-term therapy of pain syndrome regardless of origin;
• rheumatic damage of the periarticular soft tissues;
• symptomatic treatment of rheumatic diseases;
• ankylosing spondylitis;
• osteoarthritis;
• articular syndrome with acute gout;
• rheumatoid arthritis.

What are the benefits of Xephocam injections? The preparation is administered in the form of injections for short-term treatment of acute pains of moderate, mild and moderately strong character.

Contraindications

Use of the drug Xefokam instruction prohibits when:

• heart failure;
• ulcerative colitis;
• ulcers of the stomach or duodenum in the acute stage;
• hemorrhagic stroke;
• disorders of blood clotting;
• kidney disease of severe form;
• hearing loss;
• bronchial asthma;
• dehydration, hypovolemia (decrease in blood volume);
• deficiency of glucose-6-phosphate dehydrogenase;
• significant violations of hepatic functions.

The use of Xsefokam is contraindicated in patients who have not reached the age of 18, pregnant women and patients breastfeeding.

Ksefokam preparation: instructions for use

How to drink tablets - dosage

The medicine is taken orally before meals, with 100 ml of water.

With a moderately severe pain syndrome, the drug is taken at a dose of 8-16 mg per day, divided by 2-3 doses. The maximum daily dose is 16 mg.

For rheumatic diseases of an inflammatory-degenerative nature, 12 mg is recommended as the initial dose. The usual daily dose is 8-16 mg.

The exact choice of the dose is performed by the doctor based on the patient's condition, and the duration of treatment depends on the clinic and the course of the illness.

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With lesions of the digestive system, people with impaired renal or liver function, elderly patients or after volume operations - the maximum daily dose is set at the rate of 12 mg of the drug per day, divided by 3 reception.

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To reduce the likelihood of adverse events, the minimum effective dose size should be given by the least short course.

Prisms for Xefokam: instructions for use

Injections are used only parenterally.

In the treatment of pain after surgery, Xephocam injections are given intravenously or intramuscularly, in the treatment of acute lumbago or ishalgia - only intramuscularly.

The initial dose of injection can be 8 or 16 mg. With a weak analgesic effect after the administration of 8 mg of the agent, it is permissible to additionally introduce one more such dose.

Drug injections, used as maintenance therapy, are given at a dose of 8 mg twice daily. The maximum daily dosage is 16 mg.

The solution for parenteral administration is prepared before use, for which the contents of the vial are dissolved in 2 ml of water for injection. Then the needle is replaced. Intramuscular injections are done only with a long needle.

The drug solution prepared in this manner is administered intramuscularly or intravenously. Duration of injection with the intravenous method should be more than 15 seconds, with intramuscular - more than 5 seconds.

Side effects

In the reviews of Xefokam indicate that the drug can cause:

• palpitation;
• dry mouth;
• bleeding disorders;
• edema;
• shortness of breath;
• increased blood pressure;
• stomatitis;
• sweating;
• rash;
• exfoliative dermatitis;
• excitement;
• sleep disorders;
• bronchospasm;
• allergic rhinitis
• headache;
• dizziness;
• noise in ears;
• chills;
• drowsiness;
• impaired vision and hearing;
• fluctuations in body weight.

The use of the drug can also be accompanied by dyspepsia, including flatulence, pain in the abdomen, nausea, vomiting, peptic ulcers, rectal and intestinal bleeding, changes in kidney function, anorexia.

Drug Interactions

With the simultaneous use of the drug Xefokam with cimetidine, the concentration of lornoxicam in plasma increases. Interaction with ranitidine and antacids was not revealed.

With the simultaneous use of the drug Xefokam with anticoagulants or aggregation inhibitors platelets may increase bleeding time and increase the risk of bleeding (necessary control of MHO). Simultaneous use with fenprokumonom reduces its effectiveness.

With the simultaneous use of non-steroidal anti-inflammatory drugs (NSAIDs) and heparin in combination with spinal / epidural anesthesia, the risk of spinal or epidural hematoma.

With the simultaneous use of Xefokam, the hypotensive effect of beta-adrenoblockers and ACE inhibitors decreases.

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Reduces diuretic effect and hypotensive effect of diuretics. Reduces renal clearance of digoxin.

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At simultaneous application with antibiotics of group of quinolones the risk of development of a convulsive syndrome increases.

When used simultaneously with other NSAIDs or glucocorticosteroids (GCS), the risk of bleeding from the gastrointestinal tract increases. Xefokam increases the concentration of methotrexate in the serum.

When used simultaneously with selective serotonin reuptake inhibitors (eg, citalopram, fluoxetine, paroxetine, sertraline), the risk of bleeding from the gastrointestinal tract increases.

Together with cefamandole, cefoperazone, cefotetan, valproic acid increases the risk of bleeding. With simultaneous application with tacrolimus, the risk of nephrotoxicity increases.

special instructions

In the case of hypertension or anemia, it is necessary to weigh the possible risks and benefits before applying Xefokam. therapy, since it is possible to develop gastrointestinal bleeding, peptic ulcers, diabetes mellitus with impaired function kidney.

If long-term treatment with this drug is necessary, it should be borne in mind that the healing of ulcers of peptic character slows down when lornoxicam is taken. In case of bleeding, it is necessary to stop taking this medication and apply adequate therapy.

Patients with pathologies of the gastrointestinal tract with the taking of Xephocam tablets and other medicinal forms of the drug need medical supervision. With hypovolemia, the use of medication is possible only accompanied by adequate hydration because of the high risk of reducing renal perfusion.

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In case of symptoms of neuropathy, the drug should be discontinued because of the threat of developing papillary necrosis and acute renal failure.

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Patients over 65 years of age, patients with hypertension, obesity, with diuretics, nephrotoxic drugs need to monitor the function of the kidneys and blood pressure throughout the course of treatment Xefokam.

If it is necessary to take the drug for a long time, it is recommended to periodically perform a clinical analysis of blood, kidney and liver samples.

In reviews of Xefokam indicate that the drug reduces concentration of attention, so during treatment, it is necessary refrain from performing work that requires increased attention and speed of psychomotor reactions, as well as from admission alcohol.

This drug is not recommended for use with hereditary intolerance to galactose, lactase deficiency, or impaired glucose-galactose absorption. In addition, lornoxicam should not be used in women during pregnancy planning.

Medication analogues Xefokam

The same active substance contains an analogue of Xefokam Rapid.

Analogues have a similar effect:

• Meloksikam.
• Remoxicam.
• Lem.
• Matarin.
• Medsikam.
• Tenoktil.
• Melbek forte.
• Melbeck.
• Tobitil.
• Movalis.
• Mesipol.
• Revmadore.
• Aktameloks.
• Meloksam.
• Sanik.
• Meloflex.
• Forte chondroxide.
• Hotemin.
• Exen Sanovel.
• Meloflam.
• The pyroxyl.
• Mixol Ah.
• Meloks.
• Kalmopyrol.
• Tenikam.
• Amelotex.
• Arthrosan.
• Feldoral.
• Vero Piroxicam.
• The Texman.
• Bee-ksikam.
• Matarin plus.
• Mirlocks.
• Tilcotyl.
• Pirokam.
• Movix.
• Piroxicam.
• Velden.
• Finalgel.
• Movasin.

Price

Tablets Ksefokam buy in Moscow can be for 195, injections - for 700 rubles. The price of the drug in Kiev and Ukrainian cities is 56 hryvnia.

In Minsk, pharmacies offer to buy a remedy for 7-16 bel. rubles.

In Kazakhstan, it costs 3870 tenge (Xefokam 8 mg (lornoxicam) No. 5 injection for NYCOMED AUSTRIA, GmbH (Austria)).

Reviews

Patients about Xefokam injections say, as well as about tablets. They highly appreciate their analgesic effect.

However, the drug is quite toxic and can cause severe damage to the liver, kidneys and stomach, which is confirmed by the reviews doctors and patients, therefore it is unsuitable for systematic use in order to relieve the chronic pain syndrome.

"I did not notice any side effects from Xefokam."

"Until now, only Celebrex can be compared to Xephocamus (with a lot of serious side effects and a more delayed onset of relief)."

"Action is likely to all be absolutely individual. My pain relieves hours by 7-8. But, it seems to me, the first five days of the injections removed the pain longer. "

"Xefokam, unlike other painkillers, does not reduce the sensitivity of the nerves locally, but it stops the flow of signals about pain in the brain. Then it was an absolutely innovative method. Due to what the pain relieves the drug much more reliably. "

"Always as soon as teeth or gums begin to hurt (they are very sensitive and often inflamed) - I drink it, it helps to wait until the doctor visits. In addition, it has anti-inflammatory properties, which is also very important. I drink one tablet, I have enough. "

"It can be safely drunk with alcohol intoxications of degrees of low and medium. When severe it is not particularly recommended, but if necessary, you can also take it. This is the difference between many drugs. "

"Somehow my wrist hurt, it's just terrible, the pain and symptoms were like with arthritis (I have a tendency, because on this arm the joint is slightly deformed). I was saved only by xeafokam, although I did not drink it at once, for some reason I was careful. And after taking it almost immediately everything went away. "

A source: http://remedy.ucoz.ru/index/ksefokam_ot_chego_pomogaet_instrukcija_po_primeneniju_cena_otzyvy_analogi/0-502

Injections Xsefokam: instructions for use, indications, the price of ampoules, reviews and analogues

Very often acute osteochondrosis, especially in the lower back or neck, causes so intense pain that it is almost impossible to eliminate them with the help of ointments or tablets. Then doctors prescribe injections, which are much more effective to relieve inflammation and pain.

But it should be borne in mind that anti-osteochondrosis treatment involves the whole complex therapeutic measures such as NSAIDs, vitamin B preparations, physiotherapeutic procedures and etc.

Often to relieve exacerbation, Xefokam injections are used. These injections belong to the group of non-steroidal anti-inflammatory drugs, contribute to the rapid removal of pain syndrome.

Therapeutic effect of Xefokama pricks

Thanks to the analgesic and anti-inflammatory effect, Xefokam injections are successfully used to eliminate pain in osteochondrosis and rheumatic pathologies.

After the administration of the drug, its active components begin to suppress the formation of prostaglandins.

These are fat-like substances that play a leading role in various inflammatory processes.

Enzyme substance cyclooxygenase helps to be produced from arachidonic acid by special bioactive compounds called prostaglandins.

These prostaglandins belong to the mediators of inflammation, in other words, they activate and then support the development of all possible inflammatory phenomena.

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When the isoenzymes of cyclooxygenase are blocked, the production and formation of prostaglandins cease. As a result, the pathological inflammatory process gradually stops and disappears.

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It should be noted that unlike analgesics of narcotic groups, Xefokam injections do not have an opioid-like effect on the central nervous system,the drug does not lead to the formation of dependence and habituation, does not affect respiratory functions and does not provoke constipation.

Composition of solution

The injections are manufactured in the form of a lyophilizate, intended for the preparation of an injection solution.

A lyophilizate is first called frozen, and then dried in a vacuum preparation.

The active substance of Xsefokam injections is Lornoxicam.

Auxiliary components: trometamol, mannitol, etc.

Indications for the use of injections

Xefokam injections are recommended for use in the following cases:

• Necessity of immediate relief of the pain syndrome caused by the operation;
• With systemic lupus erythematosus;
• Cupping of ischialgic, myalgic, head, dental, migraine painful attacks;
• Elimination of pain during exacerbation of osteochondrosis, arthralgia;
• Soreness with extensive burns;
• Symptomatic treatment of osteoarthritis, rheumatoid, psoriatic or infectious arthritis, exacerbation of gout, bursitis of different localization, etc.

Contraindications

According to the instructions, Xefokam's injections can not be categorically done in the following cases:

1. With myocardial insufficiency;
2. Pronounced abnormalities of hepatic or renal activity;
3. If you suspect or have hemorrhagic stroke;
4. The presence of hypersensitivity to aspirin or anti-inflammatory nonsteroidal drugs such as Indomethacin or Ibuprofen;
5. An aggravated gastrointestinal ulcer;
6. With bronchial asthma;
7. When intolerant to Lornoxicam and other components of the drug;
8. With auditory disorders;
9. The presence of blood flow disorders or diathesis of hemorrhagic nature;
10. With dehydration or reduced blood volume;
11. Presence of ulcerative nonspecific colitis;
12. Up to 18 years;
13. Pregnancy, lactation.

Side effects

In some patients, injections may result in adverse reactions. The manufacturer in the instruction indicates such effects:

• A state of drowsiness or arousal;
• Auditory disorders such as extraneous noise or hearing loss;
• Dizziness and headaches, sometimes migraine;
• Depressive states;
• Sleep disorders, hallucinogenic manifestations;
• Neuropathy (pathology of nerves, causing motor disorders), dysarthria (inarticulate speech);
• Viral meningitis or syncopal conditions (short-term loss of consciousness with a simultaneous decrease in muscle tone).

In addition to the above, there may be reactions that affect the digestive system and GIT. They can appear:

• Emetic urges and nausea;
• Gastric pain;
• Diarrhea;
• Inflammatory lesions of the oral, esophageal and gastric mucosa;
• Bloating;
• Ulceration or bleeding of gastrointestinal organs;
• Failures in the work of the liver;
• Inflammatory processes in the pancreas;
• Difficulties in swallowing;
• Digestive disorders;
• Inflammatory lesions in the large intestine, etc.

In addition, sometimes patients noted the occurrence of certain disorders in the hematopoietic, cardiovascular, respiratory, musculoskeletal, urinary and other systems. There may be allergic symptoms, general malaise, redness and some soreness at the injection site, etc.

Instructions for the use of injections

Injection must be performed in a jet, in other words, insert a needle into the muscle and release the injection solution with a jet. In flasks of brown glass lyophilizate is placed. From it, a solution is prepared for intramuscular injection. The solution must be prepared immediately before the injection.

Although the instruction warns that, if necessary, it is allowed to store the ready-made injection solution for a day in the refrigerator (do not freeze!). After a day, the solution loses its suitability and is simply discarded.

The decision is made by the doctor.The injections can be done intravenously or intramuscularly.

Initially, inject a double dose of the drug (16 mg). This is done to quickly and reliably eliminate the pain syndrome.

The maximum possible daily dose is 16 mg (2 flacons).

For elderly patients (over 65 years), patients after surgery and persons weighing less than 50 kg, it is recommended to reduce the dosage in half.

In other words, the initial shock dose for such patients is 1 vial (8 mg), and maintenance treatment is administered at a dosage of 4 mg twice a day.

The course of Xefokam therapy should be short-lived. After the pain symptomatology is eliminated, the administration of the drug by injection should be discontinued. If necessary, the patient is given Xefokama tablets.

Than to develop a medicine Xefokam?

Powder Xefokama must be diluted with special water. One bottle of powder requires 2 ml of liquid. Often, water comes in a package with bottles of powder, but if it is not provided, then it is purchased separately at pharmacies.

This fluid is considered the most optimal for dilution of injection solutions, it is distilled and deionized.Therefore, the injection solution diluted with such a liquid will be the most effective, and the risk of developing adverse reactions is minimal.

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To prepare the solution, water from the ampoule is drawn into the syringe, then poured into the lyophilizate. Be sure to shake the bottle gently to allow the powder to completely dissolve. The prepared solution is yellow, it looks transparent and does not have any inclusions.

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If the injection water was not at hand, and the injection should be done, you can dilute the powder with sterile saline, lidocaine or novocaine.

Overdose

Exceeding the dosage of the drug provokes a vivid and intense manifestation of adverse reactions.

The patient has such symptoms:

• Violations of motor coordination;
• Nausea and vomiting;
• Dizziness with loss of consciousness;
• Convulsions;
• Coma;
• Renal and hepatic insufficiency;
• Blood flow disorders.

Interaction

Xefokam injection is not recommended to be performed simultaneously with antithrombotic, hypoglycemic, diuretic, antihypertensive drugs, as well as NSAIDs, antidepressants and so on. The possibility of comprehensive treatment should consult a doctor.

The price of ampoules

The average price in pharmacies in the country and in Moscow for bottles Ksefokam No. 5 for 8 mg + solvent for lyophilizate - 694-768₽.

Analogues

Analogues of injections Xefokam are the means of NSAIDs of the group, characterized by pronounced anti-inflammatory and analgesic action:

• Amelotex;
• Bee-ksikam;
• Liberalum;
• Melbeck, Melbeck-Forte;
• Meloflex Rompharm;
• Mesipol;
• Movalis;
• Movasin;
• Teskamen and others.

Reviews

The drug has a lot of pobochek, so the patient's comments about him developed ambiguous.

In all cases, the injections showed efficacy, but the presence of adverse reactions caused a lot of negativity on the part of consumers.

In order not to be among the disappointed, do not do self-assignment, it is better to consult a specialist beforehand.

Anna:

Tatyana:

A source: http://OsteoHondroza.net/medikamenty/inektsii/ukoly-ksefokam.html

What helps "Xephokam". Instructions for use

Effective pharmacological means to help cope with the severe pain syndrome - injections and pills "Xefokam."

What helps the medicine? Excellent in the symptomatic therapy of various pathologies of rheumatoid nature drug "Xefokam."

The instructions for use indicate that he is a representative of a subgroup of non-steroidal anti-inflammatory drugs, a subclass of oxycomas.

In what form is it produced

In the pharmacy network, the drug "Xefokam which helps with pain syndrome, is presented in several forms:

• protected by a special film of tablets - 4 mg and 8 mg, in a package of cardboard 10 pcs .;
• lyophilizate for further solution preparation - parenteral route of drug administration, in a consumer package of 5 pcs.

However, the form of the ointment or gel of the agent is not available. The optimal way of medication administration is determined by a specialist - based on the diagnosed pathology of the patient and his general health status.

Active and auxiliary components

According to the instructions attached to each pack with the drug "Xefokam 1 tablet of the drug may contain the active ingredient Lornoxicam in a volume of 4 mg or 8 mg. It is his inherent pronounced anti-inflammatory and analgesic effect on the human body.

From auxiliary substances are indicated:

• for the injection form - edetate disodium and trometamol with mannitol;
• for the form of tablets - magnesium stearate and povidone K25, as well as sodium croscarmellose and cellulose, lactose monohydrate.

Their main purpose is to maintain and enhance the medicinal properties of the basic substance.

Available pharmacological actions

Since the drug is a vivid representative of a subgroup of non-steroidal anti-inflammatory drugs, it has their basic pharmacological mechanisms of action on the human body.

There is a pronounced analgesic, as well as anti-inflammatory effect. This activity of Lornoxicam is due to its ability to actively inhibit the activity of cyclooxygenase isoenzymes. Against this background oppression of prostaglandins.

It also suppresses the release into the bloodstream of free radicals.

From the instructions to the drug "Xefokam" it follows that there is no effect on opioid receptors in the neural structures of the brain.

There is also no effect of rapid addiction, as well as dependence on the drug.

After entering the body, the active substance of the drug is rapidly absorbed in the upper gastrointestinal tract. The processes of metabolism occur in hepatocytes. Excretion of metabolites occurs with bile, and only partially with urine.

Injections, pills "Xefokam what helps and when appoint

The main direction of the drug "Xefokam" can be found in detail from the instructions attached to the package with medication.

Tablets should be taken in the following cases:

• short course in severe pain, regardless of its origin;
• symptomatic therapy for rheumatoid pathologies - for example, ankylosing spondylitis, gouty articular syndrome, rheumatoid arthritis of the joint and soft tissues.

What helps "Xefokam" in the injections? The injection form of the medication, as a rule, is used to stop the intense pain syndrome. It is not advisable to use them for a long time.

Existing contraindications

Like any medicine, "Xefokam the instruction for use reports this, it has a certain list of absolute and relative contraindications:

• available in the anamnesis information about allergic reactions to other NSAIDs;
• existing bleeding disorders;
• period of exacerbation of ulcerative pathology of the upper or lower gastrointestinal tract;
• decompensated condition in the kidneys, liver;
• individual hyperreaction to active and auxiliary components of the medicine "Xefokam from which tablets or injections can cause allergies;
• formed dehydration or hypovolemia;
• hyperkalemia.

The instructions also indicate pathological conditions that are not compatible with taking Xefakam:

• suffered strokes of hemorrhagic form;
• bronchial asthma, especially aspirin type;
• deficiency of glucose-6-phosphate dehydrogenase;
• hearing loss;
• severe condition of insufficiency in the cardiovascular system;
• children and adolescence;
• period of gestation of the baby and its subsequent lactation.

Particular care should be taken when using the medication in patients aged 65-75 years, as well as having a tendency to abuse tobacco and alcohol products.

The drug "Xefokam instructions for use

Pills

The manufacturer in the instructions for the tablets "Xefokam" indicates the oral route of ingestion. It is recommended before meals, accompanied by a moderate amount of water.

If a person has a moderate pain syndrome, the medicine is recommended to take 1-2 pills. per day, reception can be carried out in several stages. The maximum dose for a day is up to 16 mg.

With the available pathologies of the rheumatic origin, with the inflammatory-degenerative variant of the flow, the starting dose is 8-12 mg, then the daily dose reaches 8-16 mg.

The optimal dose is selected only by a specialist - based on the diagnosed disease, the severity of the symptoms, as well as the age category of the person and his general state of health.

With the existing relative contraindications - in the disorder of kidney, liver structures, elderly age, conditions after surgery, the average daily dose is determined individually. Typically, it is 12 mg in three divided doses.

In order to reduce the risk of the formation of undesirable manifestations from the medication, experts recommend the minimum dose size of the medication that provides the desired curative effect, minimum course.

"Xefokam" injections: instructions for use

Lyophilizate for further preparation of the solution is recommended for use with an intensive pain syndrome, a short course. The solution can be administered not only intravenously, but also intramuscularly.

The starting dose of the drug may be 8 mg and 16 mg. With a slight anesthetic effect from the 8 mg administered, it is permissible to administer as much of the same drug solution.

In order to carry out maintenance therapy, an expert can recommend the administration of 8 mg of the agent twice a day. The maximum dose per day is 16 mg.

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Injections are always recommended for the minimum duration of the course, with the lowest dose that can have the desired effect. A solution for the parenteral route of administration is prepared immediately prior to administration.

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The contents of the vial are previously dissolved in two milliliters of water for injection. After replacing the needle, the device is dialed into the syringe and the insertion procedure is performed.

Intramuscular injection is performed only with a long needle - to achieve maximum depth of injection. If the medication is delivered intravenously, the duration of the procedure should be at least 15-20 seconds, with intramuscular - about 5-7 seconds.

Undesirable effects

In most cases, the drug "Xefokam" side reactions does not cause and is well tolerated by patients. Seldom there can be various undesirable effects:

• propensity to depressive states;
• leukopenia;
• increased bleeding parameters;
• hemorrhagic variant of rashes;
• thrombocytopenia;
• pharyngitis;
• individual hypersensitivity;
• anorexia;
• sleep disorder;
• confusion of consciousness;
• increased nervousness;
• persistent pain impulses in the head;
• different intensity of dizziness;
• increased drowsiness;
• paresthesia;
• disorders of taste;
• the appearance of a tremor;
• migraine attacks;
• conjunctivitis;
• decreased vision;
• noise in the head or ears;
• tachycardia and various manifestations of heart failure;
• tides;
• arterial hypertension;
• increasing shortness of breath;
• cough and bronchospasm;
• gastralgia,
• dyspeptic disorders;
• ulcerative defects of mucous membranes of different localization;
• glossitis;
• aphthous variant of stomatitis;
• myalgia and arthralgia;
• dysuria;
• hyperemia and tenderness at the injection site.

After drug withdrawal, all of the above negative actions, as a rule, are eliminated on their own.

Analogues of the drug "Xefokam"

Substitution of the drug can serve as analogs:

1. Meloks.
2. "The Sanicants."
3. "Melbeck".
4. The Tenikam.
5. "Velden."
6. Aktameloks.
7. "Medsikam".
8. "Remoxicam".
9. "Tilkotil."
10. Tobitil.
11. «Kalmopyrol».
12. "Meloksam."
13. "Movalis".
14. "Movix".
15. "Mesipol".
16. "Finalgel".
17. MIRLOX.
18. "Meloksikam".
19. "Pirokam".
20. The Texamen.
21. "Amelotex."
22. "Meloflex".
23. "Matarin".
24. "Piroxicam".
25. "Matarin plus".
26. Feldoral.
27. "Hotemin".
28. "Exen Sanovel."
29. "Tenoktil."
30. "Melbek forte."
31. "Movsisin".
32. "Vero Piroxicam".
33. "Meloflam".
34. "Arthrosan".
35. "Pyroxyfer."
36. "Revmadore."
37. Bee-ksikam.
38. "Forte Hydroxide".
39. "Lem".
40. "MIXOL OD".

The structure is analogous to "Xefokam Rapid."

Price

Tablets "Ksefokam" in Moscow and Russian regions can be bought for 200 rubles, for the injections will have to give 750 rubles. The price of the drug in Kiev reaches 60 hryvnia. In Minsk, the means are being implemented for -16 bel. in Kazakhstan - for 3900 tenge.

Reviews

At the forums devoted to the discussion of the drug "Xefokam most of the reviews are positive. People emphasize the rapid onset of anesthetic, as well as anti-inflammatory effect, both from taking injections and pills to "Xefokam".

However, a toxic effect can come from the medicine - a special danger to the structures of the liver and kidneys. Therefore, only a specialist should recommend to take the medicine, after preliminary careful assessment of the patient's general health.

Medical staff also indicate the unfitness of the drug for systemic use - it is recommended only for a short course, with the aim of eliminating the pain syndrome.

A source: http://OtchegoPomogaet.ru/ksefokam-instrukciya-po-primeneniyu.html

Xefokam: instructions for use

The drug Xefokam belongs to the group of NSAIDs and is widely used in different directions of medicine to relieve pain, inflammation, hyperemia and hyperthermia.

Form of release and composition of the medicinal product

Xephocam is available in the form of lyophysiata for the preparation of a solution for further injection. The medicine is packed in glass dark bottles complete with a solvent in plastic pallets for 1, 5 and 10 bottles in a cardboard box with the attached instruction.

The contents of the vial is a dense mass with a yellowish hue, the main active ingredient of which is Lornoxicam, in one vial 8 mg of the active ingredient. A 2 ml ampoule with water for injection is applied to the preparation, which is used as a solvent.

pharmachologic effect

The drug belongs to the group of non-steroidal anti-inflammatory drugs. The therapeutic effect of lyophysiate is the rapid elimination of pain and inflammation.

The mechanism of action of the active component of the drug is to suppress the synthesis of prostaglandins - substances that are responsible for the progression of the inflammatory process in the body.

Analgesic effect is not associated with oppression of the central nervous system like opioid analgesics, does not affect respiratory function, respiratory rate and heart beats per minute when administered orally in therapeutic doses.

Indications for use of the medicine

Xephocam injections are prescribed for patients to relieve pain syndrome of varying intensity and origin:

• Headache;
• Toothache;
• Pain in the joints;
• Muscle pain caused by trauma or inflammation;
• Migraine;
• Severe menstrual pain.

Contraindications

Before starting therapy, the patient should read the attached instructions in detail, as Xsefokam has a number of the following contraindications:

• Bronchial asthma, bronchial obstruction and history of apnea;
• Polyps of the nasal cavity;
• Individual intolerance of drugs from the group of non-steroid drugs, allergic reactions in the history;
• Severe thrombocytopenia;
• Hereditary predisposition to bleeding, especially in patients at risk - peptic ulcer, hemophilia, weak blood vessels, poor blood coagulation;
• The rehabilitation period of the patient after the surgical aortocoronary bypass surgery;
• Erosive gastritis;
• Hemorrhagic vasculitis;
• recently suffered hemorrhagic stroke;
• aspirin ulcer in anamnesis;
• decompensated chronic heart failure;
• severe hepatic insufficiency or liver disease, accompanied by a violation of the function of the organ;
• renal failure with signs of hyperkalemia, capercalcemia;
• dehydration of the body with obvious signs of disturbance of the water-salt balance;
• pregnancy and lactation;
• age to 18 years due to lack of clinical experience;

The relative contraindications (when the drug can be used with caution) are:

• presence of Helicobacter pylori bacteria in the body;
• cardiac ischemia;
• arterial hypertension;
• diabetes;
• smoking patient;
• alcoholism;
• severe mental illness;
• moderate renal insufficiency;
• the age of the patient is more than 60 years.

Method of application and daily dosage of the drug

The drug Xefokam is intended only for injection intramuscularly or in a vein. After the operations, with a severe pain syndrome in the lumbar region, the drug is administered between the vertebrae in the lumbar region.

The initial daily dose of the drug is 1 bottle, previously diluted with water for injection. The injection is done once a day.

The maximum daily dose of the drug should not exceed 16 mg, that is 2 injections. When intramuscular introduction should keep the needle at a right angle and insert it deep into the muscle.

The solution is administered slowly, which reduces the likelihood of side effects.

Use in pregnancy and lactation

Injuries to Xefokam are forbidden to use in women during pregnancy, as this can lead to the development of intrauterine pathologies on the part of the kidneys, the brain and the systemic hematopoiesis of the fetus.

When planning pregnancy during the period of therapy with the drug should be effectively protected, and after the drug is canceled, take a break in planning for at least 3 months.

Active ingredient of the drug Xefokam can be excreted in breast milk, therefore use of this product is incompatible with lactation. If therapy is necessary for a woman, it is recommended to stop breastfeeding the baby and transfer it to milk formula nutrition.

Adverse Events

Against the background of using a drug from a group of nonsteroidal anti-inflammatory drugs, side effects most often develop from the gastrointestinal tract. These include:

• nausea, vomiting;
• increased salivation;
• pain in the stomach;
• exacerbation of chronic diseases of the digestive canal;
• lack of appetite;
• diarrhea;
• enlargement of the liver and suppression of its function;
• risk of developing gastrointestinal bleeding.

Less common are other side effects: thrombocytopenia, skin rash, dizziness, changes in blood pressure, tremor of limbs, bronchospasm. At the injection site, local side reactions may develop - redness, swelling, tenderness of the puncture site

In very rare cases, it is possible to develop angioedema and signs of anaphylaxis.

Overdose

If the dose prescribed by the doctor is met, signs of a lyophysiate overdose are rarely seen.

Most often, they develop with drug abuse and prolonged use of the drug.

When developing the first signs of an overdose or accidentally administering a large dose, the patient's medicine is sent under the supervision of a doctor and, if necessary, symptomatically treated.

Interaction with other medicinal products

With the simultaneous administration of Xefokam with cimetidine, the concentration of the main the active ingredient of lyophosphate in the blood plasma, which increases the risk of developing the above-mentioned phenomena.

It is not recommended to combine the drug with anticoagulants or antiaggregants, as this can lead to severe hemorrhagic complications.

With the simultaneous use of the drug with heparin during epidural anesthesia, the patient is at increased risk of developing a massive hematoma at the site of the injection.

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Xefokam reduces the therapeutic effect of beta-adrenoblockers and diuretics, and also reduces renal clearance of Digoxin.

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When the drug is combined with antibiotics from the quinolone group, the patient develops a risk of developing convulsive seizures. With the simultaneous use of glucocorticosteroids against the background of Xefokam treatment, the risk of bleeding increases.

special instructions

Patients with peptic ulcer or erosive gastritis in the history of treatment with Xefokam should be carried out with extreme caution. If there is a suspected bleeding, the therapy is immediately stopped.

Under the influence of the drug, platelet aggregation is inhibited, which can lead to an increase in the time of blood coagulation.

Patients who are to undergo surgery should be sure to warn the doctor about the therapy with this remedy, and the doctor in turn should strictly control the patient's condition during the operation, keeping medicines at the ready stop bleeding (aminocaproic acid, eg).

During treatment, patients should not drink alcohol and manage mechanisms that require increased concentration.

Analogues of the drug Xefokam

According to their therapeutic effect with the drug Xefokam similar means:

• Xefokam Rapid Tablets;
• Nurofen tablets;
• Ibuprofen tablets;
• Acetylsalicylic acid.

Before replacing the drug with one of these analogs, the patient should consult a doctor, since the listed products have different active ingredients and dosage.

Leave and storage conditions

Liofi Asia can be purchased at pharmacies on prescription. Vials with the drug should be stored in the refrigerator away from children.

Before each injection, it is necessary to prepare a fresh solution, making sure that the contents of the vial are evenly dissolved, and that the syringe is free from suspensions and flakes.

Shelf life of the drug is 2 years, provided that the storage rules were strictly observed.

Xefokam Price

The average cost of lysofiata Ksefokam in Moscow pharmacies is 192 rubles.

A source: http://bezboleznej.ru/ksefokam