Eye drops Betofan: indications and application features

Glaucoma is a serious eye disease, the consequences of which can be irreversible and dangerous. There are many medicines designed to treat this ailment. One such medication is Betofan eye drops. The medicine is referred to as beta-blockers due to the mechanism of action. In this article, we will take a closer look at the preparation of Betofan, reveal the features of its use, point out the side effects and contraindications.

Description of the preparation

Betofan refers to antiglaucoma drugs.These eye drops reduce intraocular pressure by suppressing the production of intraocular fluid. The action of the drug is directed to beta-1 receptors, which it selectively blocks. A medicinal solution in the form of eye drops is produced.

Eye drops Betofft contain in its composition betaxolol hydrochloride (5 mg / ml).The solution is usually colorless, sometimes light yellow or brown. Among the auxiliary components, the medicine contains:

• Sodium chloride;
• Dodecahydrate sodium hydrophosphate;
• Purified water;
• Monohydrate sodium dihydrogen phosphate;
• Benzalkonium chloride;
• Dihydrate edetate disodium.

Flasks-droppers are made of a special polymer and contain 5 ml of drug solution.

Pharmacological action and group

The action of Betofan is mainly aimed at reducing intraocular pressure. The main component of the drug betaxolol is a selective blocker of beta 1 receptors.

In the case of local use, Betofanum leads to normalization of pressure inside the eye, regardless of the initial level (elevated, normal).The effect occurs in half an hour and is associated with a decrease in the production of intraocular moisture. The maximum decrease in pressure is observed after 2 hours after the administration of the drug. The effect of the drug is maintained for 12 hours.

The main component of the drug betaxolol, unlike other beta-blockers, does not reduce the level of perfusion pressure in the optic nerve, does not provoke a spasm of accommodation and miosis.

Indications and contraindications for use

The preparation of Betofanum is prescribed to patients with such disorders as:

• Increased intraocular pressure;
• Closed-angle glaucoma(as an additional treatment after receiving miotikov);
• Chronic form of open-angle glaucoma.

Contraindications

Betofan is contraindicated in the following cases:

• If there is a violation of the rhythm of the heart (sinus bradycardia, SSSU, AV blockade of 2 or 3 degrees);
• Patients with increased sensitivity to the content of the drug;
• In childhood (up to 18 years).

Caution should be given to the preparation of Betofan in patients with such pathologies as:

• Thyrotoxicosis;
• Raynaud's syndrome;
• Diabetes;
• Bronchial asthma;
• Theosromocyte;
• Obstructive bronchitis;
• Heart failure.

Do not prescribe Betofan to children under 18 years of age due to the lack of convincing data on its safety.

Application during pregnancy

The period of childbearing is especially important for any girl, so the taking of any medicines is allowed only in extreme cases. The same applies to the preparation Betofan.

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During pregnancy, use of these eye drops is not recommended.However, if there is a special need, Betofan is allowed for use by pregnant women, but under the strict supervision of an ophthalmologist.It is desirable that the future mother in this period was in the hospital; in this case, the doctor can monitor the effect of the drug on the nascent organism.

During breastfeeding from taking the medicine, Betofan must be abandoned. This is due to the fact that the active substance has the ability to penetrate the mother's milk into the baby's body.

Dosing and Administration

The eye solution of Betofan is instilled in 1-2 drops in the area of ​​the conjunctival sac in the morning and in the evening. It should be remembered that not always the expected effect of the drug comes at once, therefore it is necessary to measure intraocular pressure during the first month of treatment.If the background of monotherapy reduces the value of intraocular pressure fails, then apply additional medication as prescribed by the doctor.

Recommendations for use

To avoid complications during the use of the drug, the following recommendations should be adhered to:

• The solution of Betofan contains benzalkonium chloride in its composition, which is a preservative and can accumulate in soft contact lenses, damaging the eye tissues.Therefore, before instillation of the solution, the lens should be removed. You can not wear them again for more than 20 minutes.
• To ensure that the solution is always kept sterile, do not touch the surface of the eye when digging.
• Before surgery with the use of general anesthesia, the solution of Betofan to the patient is gradually canceled.
• Patients in whom the administration of Betofan solution causes a temporary decrease in visual acuity should not be immediately followed by instillation behind the wheel or working with potentially dangerous mechanisms.
• The drug solution Betofan is stored in a dry, dark place (away from children) at a temperature of up to 25 ° C.
• Shelf life of eye drops Betofan - 3 years. In the opened vial, the solution can be stored for up to 4 weeks.

We also recommend that you read the instructions for eye drops Ganfort.

Interaction with other drugs

If the patient takes several medicines, then he needs to be aware of the possibility of combining certain drugs. It should be borne in mind that:

• With the simultaneous use of preparations of Betofan and Adrenaline, mydriasis may occur.
• In a combination of drugs, depleting supplies of catecholamines (reserpine), possible lowering of blood pressure, bradycardia.
• In complex therapy with systemic beta-blockers, the risk of side effects increases due to the overall effect.
• Solution Betoftan is able to enhance the effect of psychotropic drugs, muscle relaxants, hypoglycemic drugs.
• When administered, the drug can enter the systemic circulation and give the same side effects as with parenteral administration of beta-blockers.
• Betofanum has minimal effect on blood pressure and vascular system.However, care should be taken when prescribing it to hypertensive patients and patients with heart failure. Treatment should be stopped when the first signs of decompensation of the cardiovascular system appear.
• With the simultaneous use of a solution of Betofan and sympathomimetics, there is a more pronounced vasoconstrictor effect of the latter.
• If it is necessary to combine the solution of Betofan with other ophthalmic preparations, it is recommended to observe the interval between their administration up to 10 minutes.

Possible complications caused by the drug

Judging by the reviews, the preparation Betofan rarely gives side effects. However, in some patients, there are:

• Local reactions:temporary discomfort in the eyes after instillation, lacrimation; very rarely - a decrease in the sensitivity of the cornea, redness of the eye, keratitis, photophobia, blurred vision, pruritus, allergic reactions, dry eyes, allergic.
• From the side of the central nervous system: dizziness, nausea, drowsiness, insomnia, headache, depression.
• From the cardiovascular system: bradycardia, cardiac conduction disorder and heart failure.
• From the respiratory system:respiratory insufficiency, bronchospasm, bronchial asthma.

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Systemic side effects are rare.

If eye contact is excessive, rinse eyes with warm water.

Among the analogs of the preparation Betofan, one can distinguish such drugs as:

• Betak;
• Betaxolol;
• Betoptik;
• Betalmik EU;
• Lokren;
• Xoneuf;
• Optibetol.

Which of these drugs to choose when increasing intraocular pressure, only the ophthalmologist decides (but not the pharmacist!).

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conclusions

Betofan is an effective medicinal product prescribed for glaucoma. Reviews about the drug are mostly positive. In addition, these eye drops are characterized by low cost, which is also an important indicator for the patient.

Among the negative moments, users notice frequent side effects, as well as many contraindications.

Read also about the preparations of Digitalpharm and Emoxipine.