Stresam is a drug from a group of tranquilizers.
The medication is prescribed in order to eliminate anxiety, internal tension, sleep disturbances, increased irritability and other psychoemotional disorders.
Stresam is a "daytime" tranquilizer, which does not provoke excessive drowsiness due to the fact that the acting component does not exert a depressing effect on the psychomotor reactions of the patient's body.
Does not cause withdrawal or addiction.
Clinical and pharmacological group
Anxiolytic (tranquilizer).
Terms of sale from pharmacies
Can buyby prescription.
Price
How much does Strezam cost in pharmacies? The average price is at the level of400 rubles.
Composition and form of release
The drug Stresam is available in the form of gelatin capsules for ingestion in blisters for 12 and 20 pieces of 2-3 blisters in a cardboard bundle. The box contains an instruction with a detailed description of the preparation.
Each capsule contains 50 mg of the active active ingredient Etiphoksin hydrochloride, as well as a number of auxiliary components: microcrystalline cellulose, magnesium stearate, talc, titanium dioxide, lactose monohydrate.
pharmachologic effect
Stresam is a tranquilizer (anxiolytic) that reduces severity or suppresses anxiety, anxiety, fear, emotional stress.
The active substance of the drug - etifoksin, refers to benzoxazine derivatives, has an autonomous regulating action. Anxiolytic activity of the drug is caused by a direct and indirect effect on GABA (gamma-aminobutylic acid) -A receptors, which improves GABAergic transfer of the pulse to the central nervous system.
Direct effects on GABA-A receptors are achieved by allosteric modulation (etifoxine mainly binds to beta2 or beta3 receptor subunits).
The indirect effect of the drug is due to an increase in the synthesis of neurosteroids, for example, allopregnanolone, which is also a positive modulator of GABA-A receptor.
Indications for use
Indications for the use of Stresam are:
- anxiety states;
- fears;
- internal stress;
- increased irritability;
- mood disorders, provoked by somatic diseases, including cardiovascular origin.
Contraindications
The use of the drug is contraindicated if the patient's sensitivity to the main or auxiliary components is increased drug, children and adolescents under the age of 18, pregnant and breast-feeding women, as well as with the following diseases and conditions:
- myasthenia gravis;
- shock states;
- impaired renal and hepatic function;
- congenital galactosemia;
- deficiency of lactose;
- syndrome of malabsorption of glucose or galactose.
Intended use for pregnancy and lactation
Clinical trials regarding the safety of the drug Stresam for pregnant women and fetuses has not been carried out, therefore capsules to future mothers can be appoint only if there are serious indications and in the event that the intended benefit to the mother exceeds the possible harm to the child.
Women who undergo treatment with the drug should be carefully protected and prevent pregnancy, in case the conception does occur, the treatment should be stopped immediately and consulted by the doctor.
The active active substance of the drug is excreted in breast milk, so if necessary, capsules Stress nursing mother should decide on the completion of lactation and the transfer of the child to artificial nutrition.
Dosage and route of administration
As indicated in the instructions for use, Stresam is applied orally (by mouth), with a small amount of water. The dose of medication is determined by the attending physician individually, depending on the patient's condition.
- Usually assigned to 1 pc. 3 times a day or 2 pcs. 2 times a day. The maximum daily dose is 150-200 mg.
The duration of therapy ranges from several days to 4-6 weeks (depending on the patient's condition).
Side effect
The drug Stresam, as a rule, is well tolerated by patients, but in individuals with increased individual sensitivity, the following side effects may develop:
- nervous system: rarely - a slight drowsiness (appears in the first days of treatment and disappears on their own for further therapy);
- genitals and mammary glands: frequency unknown - metrorrhagia in patients taking oral contraceptives;
- skin and subcutaneous tissue: rarely - skin itching, maculopapular rashes, face swelling, erythema multiforme;
- digestive system: frequency unknown - lymphocytic colitis;
- liver and biliary tract: frequency unknown - cytolytic hepatitis, hepatitis;
- allergic reactions: very rarely - angioedema, nettle rash; frequency unknown - leukocytoclastic vasculitis, anaphylactic shock, Stevens-Johnson syndrome, DRESS syndrome (drug-induced hypersensitivity syndrome with eosinophilia)
Overdose
Symptoms of overdose are lethargy, excessive drowsiness. Treatment is symptomatic, showing gastric lavage. A specific antidote to Stresa is absent.
special instructions
Before starting treatment, read the special instructions:
- Do not exceed the dose prescribed by your doctor.
- Do not combine the drug with alcoholic beverages.
- If you miss a dose of Stresama, do not double the dose at the next dose.
- Due to the presence of lactose in the composition of the drug, the drug can not be used for galactosemia, malabsorption of galactose and glucose, as well as for lactase deficiency.
Interaction with other drugs
Joint reception of Stresema and drugs that depress the central nervous system (including hypnotics, neuroleptics, barbiturates, antihistamines and opioid analgesics), leads to potentiation of the action of these drugs.
With simultaneous application with ethanol, Stresam increases its effect on the body.
Reviews
We offer you to read reviews of people who used the drug Stresam:
- Marina. A good preparation of cumulative effect (not an ambulance), removes anxiety, but not immediately, there is no addiction, you can drink for a long time. For neglected cases.
- Alla. I'm 72.. In life there were so many experiences. Now everything is fine, but past experiences are crushed like a stone. For the last 7 months she suffered from arrhythmia (heart rate misses). She is a bedridden patient. It was treated at cardiologists, has replaced 4 doctors. The psychotherapist has appointed or nominated to drink in the afternoon 2 times "Strezam", for the night 1/2 atarax. With a view of economy and fear of superfluous chemistry has decided to drink only atarax for the night. Improvements did not notice. When it became very bad, there was no choice left-either life or the liver. Chose life. After the first tablet the omissions ceased. Now I'm afraid to stop drinking. I go without stops, I work at the dacha. I would drink all my life, but you can not. I'm afraid of the day when the course ends. Be all well, take care of yourself and your loved ones.
- Maksim. This tranquilizer drank after a heavy divorce, there were insomnia, could not calm down, tremor of hands, panic attacks. Better became days through ten after the beginning of reception, drank on two tablets twice a day. The first time I had to give up driving (according to the doctor's advice), was a little sluggish, I wanted to sleep more than usual. In two weeks everything was normal. He is pleased with the treatment.
Analyzing the doctors' reviews about Stresa, we can conclude that this drug should pay special attention to people who have sedatives cause severe drowsiness.
This drug does not cause this side effect, but, nevertheless, doctors advise to observe when driving a car during the treatment of maximum vigilance, and from the management of complex mechanisms and completely abandoned. Also, doctors do not recommend the use of this sedative for the treatment of anxiety-phobic disorders in children and adolescents who have not yet reached the age of 18.
Analogues
The main analogues of the drug Stresam are tablets Trankvilar (Trancvilar) and Oxylidinum (Oxylidinum). Popular anxiolytics are also Meprobamat, Temazepam and Amizylum.
Before buying an analogue, consult your doctor.
Shelf life and storage conditions
Stresam is recommended to store at room temperatures, in places inaccessible to children! Shelf life is 3 years.
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