Furagin - instructions for use for children and adults, indications, composition, form and price

Composition and Form of Release

Furagin( Furagin) is represented by a tablet format. There are no other forms of release of the remedy. Its composition:

Description	Round yellow-orange tablets
Concentration of furazidine, mg per pcs.	50
Auxiliary components	Polysorbate, cellactose( a mixture of lactose monohydrate and microcrystalline cellulose), magnesium stearate, potato starch, potassium carbonate, hydrogen molecules
Packaging	10 pcs.in pack, packs of 1 or 3 packs with instructions for use

Pharmacological properties

The active component of the medicament belongs to the group of nitrofurans that inhibit the respiratory chain and the Krebs cycle( tricarboxylic acids), leading to the inhibition of other biochemical processes occurring in microorganisms. The drug is active against streptococci, staphylococci, Escherichia coli, shigella, proteus, Klebsiella, enterobacteria, pathogens of salmonella and lambliz.

Depending on the concentration, furazidine has bacteriostatic or bactericidal effects. Due to this, the patient's well-being is improved even before the growth of the microflora is suppressed. The effect of the drug leads to activation of immunity, increase of the complement titer, ability of leukocytes to phagocytose pathogens. Therapeutic doses of the agent stimulate leukopoiesis. To fazrazanu slowly develops resistance. After taking the tablets, the active ingredient is absorbed in the small intestine due to passive diffusion.

Absorption of material from the distal part of the small intestine is greater than absorption from the proximal and medial segments by 2 and 4 times. From the large intestine, nitrofurans are absorbed slowly. Furazidine reaches the maximum concentration in the blood after 3-8 hours, in urine is detected after 3.5 hours after ingestion. The active component is evenly distributed in the body, its concentration is higher in lymph, bile, cerebrospinal fluid, serum, saliva. In the blood and tissues, the level of furazidine is low, because it is quickly excreted in the urine.

Metabolism is subject to less than 10% of the dose of the drug, 85% of it is excreted by the kidney. If the level of the active ingredient in the urine is low, the secretion and filtration process prevails, reabsorption increases at high concentrations, secretion decreases. Furazadin belongs to weak acids, therefore in acid urine it does not dissociate, it is intensively reabsorbed. With alkaline urine, its excretion increases. The intensity of the metabolism of the drug increases with a decrease in excretory renal function.

Furagin - an antibiotic or not

Often patients are wondering whether Furagin is an antibiotic. It has antibacterial and antimicrobial properties, is part of the group of nitrofurans, affects different strains of microorganisms. In comparison with other systemic antibiotics, it does not affect blood flow, but immediately enters the urinary system, providing an antiseptic effect. For this reason, the drug is not a systemic antibiotic, it can be included in a group of antibacterial drugs of local action. It manifests itself as an excellent antiseptic.

Indications for use Furagina

Use the drug for oral or topical( external) use. Indications, according to the instructions, are:

• urogenital infections( urethritis, acute cystitis, pyelonephritis);
• gynecological diseases;
• skin infection, soft tissue;
• severe infected burns;
• prostatitis;
• inflammation of the urethra;
• prevention of infection with urological operations, catheterization, cystoscopy;
• Infectious-inflammatory diseases of the pharynx, oral cavity, wounds.

How to take Furagin

Tablets are taken orally. Adults are given 50-100 mg three times a day, children older than three years - 25-50 mg three times a day. But not more than 5 mg / kg of body weight. The course of treatment is 7-10 days, if necessary, repeated after 10-15 days. According to the instructions, to prevent infection, 50 mg is taken once a half hour before the operation or procedure of the study.

External tablets can be used 2-3 times per day for washing the wound or wetting the dressing. After dissolving the dose in a glass of warm water, you can rinse the resulting solution with the oral cavity and pharynx for infectious diseases. Repeat the procedure 2-3 times per day. When taking oral tablets recommended compliance with the protein diet.

Special instructions

Instruction for use Furagina advises to observe the rules specified in the section of special instructions. These include:

1. To prevent the development of neuritis, the administration of B vitamins is prescribed.
2. With the development of negative reactions, intoxication, the taking of the drug is canceled.
3. Seldom, but you can meet in pharmacies napkins soaked in furazidine. They have a good hemostatic effect, protect the wounds from infection, accelerate the healing process. Napkins are used to treat burns, stop bleeding, prevent inflammation, treatment of pressure sores, trophic ulcers.

Furagin from the group of nitrofurans can be used in veterinary medicine for the treatment of domestic animals. It helps with diseases caused by bacteria, viruses, leptospira, trypanosomes, bartonella, coccidia, histomones. The drug is effective against streptococcal, staphylococcal septicemia, dyspepsia, protozoal enterocolitis, gastroenteritis, fodder toxic infections.

They treat swine erysipelas, dysentery, colisalmonellosis, pyogenic and gas infections, swelling diseases of pigs, surgical, ophthalmic and obstetric diseases. The drug is prescribed if the pathogens of the disease are resistant to antibiotics, sulfonamides. For birds, Furagin can be used for salmonellosis, uracil diathesis, streptococcosis, mycoplasmosis, staphylococcal infection, anaerobic diarrhea, pullorose, trypanosomiasis, colitispticemia, colibacteriosis.

In chickens, medication treats enterohepatitis, coccidiosis, leptospirosis, inflammation of the ovaries, oviduct. The medicine is given to animals after feeding by a course of 7-10 days, then a ten-day break is done. The dose is calculated as 5 mg per kg of body weight. The intake of nitrofurans increases immunity, improves the properties of blood serum for binding complement, adsorption and absorption capacity of liver and spleen. Use of the drug does not form post-vaccination immunity.

In pregnancy

Use Furagin for cystitis or other diseases during pregnancy or lactation( breastfeeding) is prohibited. This is due to the ability to influence the representatives of the nitrofuran group on the development of the child. Furazadine penetrates into breast milk, so it can lead to negative reactions when a newborn or fetus enters the body.

Furagin for children

According to the instructions, Furagin for children with caution is prescribed at the age of up to three years and is contraindicated up to a month. After that, the remedy can be used for diseases that can not be treated with antibiotics. The drug is not addictive, it fits well with other medicines, is well tolerated, can be used for preventive purposes. For children, the daily dosage will be 5-7 mg per kg of body weight. If the baby is less than a year, the tablets are ground into powder, mixed with milk. With prolonged treatment, the dosage is reduced to 1-2 mg per kg of body weight.

Drug Interaction

The drug instructions describe the drug interaction. This combination:

1. Simultaneous reception of furazidine with chloramphenicol, ristomycin, sulfonamides leads to a risk of oppression of hematopoiesis. Combinations are prohibited.
2. In parallel with nitrofurans, it is contraindicated taking drugs acidifying urine, which include calcium chloride, ascorbic acid.
3. Supplements of nalididic acid and drugs that increase the level of uric acid, reduce the effectiveness of the drug, increase the concentration of the active component in the plasma.
4. Medications that reduce the acidity of gastric juice, based on tri-xylene magnesium, reduce the absorption of the agent in the digestive tract.

Furagin and alcohol

During treatment with Furagin, you should refrain from drinking alcohol, because this leads to the development of side effects or strengthens them. If you take alcohol along with the medicine, develop fever, nausea, headache, pain in the heart, palpitations. The patient experiences increased anxiety, his blood pressure drops.

Side effects of

Taking tablets can lead to the development of side effects. The instruction distinguishes the following:

• liver dysfunction, nausea, loss of appetite, vomiting;
• polyneuritis, headache, dizziness;
• disorder of stool, abdominal pain;
• allergy, rash;
• vision impairment;
• drowsiness, malaise;
• chills, fever;
• multiple lesions of peripheral nerves.

Overdose

Symptoms of an overdose of Furagin, according to the instructions, are worsening of mood, inflammation of peripheral nerves, psychosis, angioedema, bronchospasm, urticaria, nausea. The liver is damaged, allergic reactions occur. Treatment consists of gastric lavage, hemodialysis, the appointment of symptomatic therapy.

Contraindications

The drug is used with caution in children under 3 years of age, with a deficiency of glucose-6-phosphate dehydrogenase. Instructions for use highlight contraindications:

• chronic renal failure;
• pregnancy, breast-feeding;
• age to the year;
• hypersensitivity to the components of the formulation or other nitrofurans, allergy to constituents.

Terms of Sale and Storage

Furagin is a prescription drug that should be stored at room temperature for 4 years.

Analogues

Furagin does not have many substitutes. These include those that exhibit the same therapeutic effect or contain the same active substance. Analogs of the drug:

• Furasol is an antimicrobial powder for topical use, contains furazidine;
• Furamag is an antimicrobial capsule based on furazidine, used to treat gynecological and genito-urinary infections.

Price Furagina

Depending on the number of tablets in the package, the manufacturer's mark-ups differ in the price of Furagin. In Moscow, it is sold through pharmacies or the Internet. Price:

Number of tablets in a pack, pcs.	Manufacturer	Internet price tag, rubles	Pharmacy price, rubles
30	Olainfarm, Latvia	250	275
Severnaya Zvezda, Russia	252	279
Obolensky pharmaceutical company, Russia	280	300
10	140	150
Aktifur capsules 50 mg 30 pcs	430	450

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Reviews

Maria, 45 years old

Last month I got sicka cystitis - somewhere caught a cold and has picked up an infection. The doctor prescribed Furagin's pills, said that this is an unusual antibiotic, which is practically safe for the body. I appreciated the effect of the medication - for a week the signs of the disease passed, and I did not notice the side effects. An excellent product, I recommend.

Vasily, 39 years old

After the operation on the bladder, I had trouble urinating. The doctor prescribed the medicine Furagin, which I took according to the instructions. Tablets are well tolerated, do not cause nausea and do not give the liver a burden, like other antibiotics. For 10 days of reception the urination was adjusted, I am glad to such effect.

Lily, 41 year

The drug Furagin was given to me before I had a cystoscopy. I was afraid of the operation, but it was successful. As the doctor said, taking pills reduced the likelihood of secondary infection of the urinary tract and prevented the development of pathologies. He said that if I get cystitis, then the pills will come in handy. They did not give side effects.